Research Explorer

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Researcher

Lies Lahousse

Publications & Research Data

Awards & Distinctions

251 Results

2025

Association of timely spirometry with lower all-cause mortality

Valerie DehondtDelphine VauterinEric DeromLies Lahousse

A1 Journal Article in CHEST

Cardiovascular safety of biologic therapies in patients with severe asthma : a nationwide cohort study in Belgium

Frauke Van VaerenberghDelphine VauterinMaxim GrymonprezLowie VanfleterenGuy BrusselleLies Lahousse

A1 Journal Article in LANCET REGIONAL HEALTH-EUROPE

Diabetes and cardiovascular mortality among restrictive and preserved ratio impaired spirometry phenotypes

Editorial material

Exploring the impact of aging on lower urinary tract symptoms : a longitudinal observational cohort study

Mauro Van den EndeGeorge Bou KheirKarel EveraertLies LahousseMarthe De BoevreFrançois Hervé

Impact of respiratory and cardiovascular drug exposure on lung function trajectories

Xander BertelsDelphine VauterinSebastian RiemannFrauke Van VaerenberghKristiaan ProesmansAndré G. UitterlindenM. Arfan IkramGuy BrusselleBruno H. StrickerLies Lahousse

A1 Journal Article in ANNALS OF THE AMERICAN THORACIC SOCIETY

Minimal adherence threshold to non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation to reduce the risk of thromboembolism and death : a nationwide cohort study

Maxim GrymonprezStephane SteurbautAndreas CapiauDelphine VauterinFrauke Van VaerenberghEls MehuysKoen BousseryTine De BackerLies Lahousse

A1 Journal Article in CARDIOVASCULAR DRUGS AND THERAPY

Ocean for health : a transdisciplinary framework to accelerate research on ocean–human health connections

Gert EveraertRaf AertsJan BourgoisAnn BuysseAdrian CovaciMaarten De RijckeEveline DiopereAlexander HooybergCarl LachatLies Lahousse et al.

A1 Journal Article in ENVIRONMENTAL SCIENCE & TECHNOLOGY

Pharmacodynamic drug-drug interactions and bleeding outcomes in patients with atrial fibrillation using non-vitamin K antagonist oral anticoagulants : a nationwide cohort study

Maxim GrymonprezAndreas CapiauStephane SteurbautKoen BousseryEls MehuysAnnemie SomersMirko PetrovicTine De BackerLies Lahousse

A1 Journal Article in CARDIOVASCULAR DRUGS AND THERAPY

Predictors of mortality and hospitalised exacerbations in obstructive airway diseases

Delphine VauterinFrauke Van VaerenberghMaxim GrymonprezGuy JoosLies Lahousse

A1 Journal Article in ERJ OPEN RESEARCH

Statins lower outpatient and hospitalised exacerbation risk beyond exacerbation history

Sam BeckxFrauke Van VaerenberghDelphine VauterinLies Lahousse

2024

A brief motivational interview for smoking cessation by Belgian community pharmacists

Delphine VauterinEline TommeleinLies Lahousse

A2 Journal Article in PHARMACY PRACTICE-GRANADA

All-cause mortality of Staging of Airflow Obstruction by Ratio-categorized patients with Chronic Obstructive Pulmonary Disease among the general population

Xander BertelsSebastian RiemannDelphine VauterinLies LahousseGuy Brusselle

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Asthma exacerbations and eosinophilia in the UK Biobank : a genome-wide association study

Ahmed Edris MohamedKirsten VoorhiesSharon M. LutzCarlos IribarrenIan HallAnn Chen WuMartin TobinKatherine FawcettLies Lahousse

A1 Journal Article in ERJ OPEN RESEARCH

Clinical recommendations for polygenic risk score-enhanced breast cancer screening : Can.Heal project

A. TahaJ. Matt McCraryJ. van RooijLies LahousseF. PaolettiE. PascucciM. VahtR. PastorinoA. M. PezzulloS. Boccia

Clinical relevance of lung function trajectory clusters in middle-aged and older adults

Xander BertelsJames C. RossRosa FanerMichael H. ChoM. Arfan IkramGuy BrusselleLies Lahousse

A1 Journal Article in ERJ OPEN RESEARCH

Current pharmacotherapy of COPD

Maarten van den BergeBianca BeghéLies LahousseSami O. SimonsLowie VanfleterenLeonardo Fabbri

Bookchapter in COPD in the 21st Century

Descriptive analysis on disproportionate medication errors and associated patient characteristics in the Food and Drug Administration's Adverse Event Reporting System

Victor PeraFrauke Van VaerenberghJan A. KorsErik M. van MulligenRowan ParryMarcel de WildeLies LahousseJohan van Der LeiPeter R. RijnbeekKatia Verhamme

A1 Journal Article in PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Detection and management of clinically relevant drug-drug interactions with direct oral anticoagulants : an intervention study in community pharmacies

Andreas CapiauEls MehuysMaxim GrymonprezInge Van TongelenThierry ChristiaensEline TommeleinGeneviève PhilippeLies LahousseTine De BackerKoen Boussery

A1 Journal Article in THROMBOSIS RESEARCH

Development of a frailty screening tool using electronic community pharmacy records

Marie CarreinEls MehuysLies LahousseMirko PetrovicEllen Van LeeuwenInge Van TongelenEline TommeleinKoen Boussery

A1 Journal Article in DRUGS & AGING

DNA methylation sites associated with rate of COPD exacerbations

Leila KarimiLies LahousseIvana ProkićPooja MandaviyaGuy G. BrusselleBruno H. StrickerKatia M. C. VerhammeNajaf Amin

Effect of pharmacotherapy on lung function trajectories in the general population

Lies LahousseXander BertelsG. G. BrusselleB. Stricker

Exploring the genetics of airflow limitation in lung function across the lifespan : a polygenic risk score study

Natalia Hernandez-PachecoAnna KilanowskiAshish KumarJohn A. CurtinNúria OlveraSara KressXander BertelsLies LahousseLaxmi BhattaRaquel Granell et al.

A1 Journal Article in ECLINICALMEDICINE

Genome-wide association study of preserved ratio impaired spirometry (PRISm)

Daniel H. HigbeeAlvin LirioFergus HamiltonRaquel GranellAnnah B. WyssStephanie J. LondonTraci M. BartzSina A. GharibMichael H. ChoEmily Wan et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Healthy Lungs For Life for Schools (HLFL4S)-expanding in Italy the pilot of an early life intervention to prevent lung disease in adulthood (a CADSET pilot project)

Paola PierucciLuigia Simona MininniEster PutignanoHans IntveenRaul ToranRobab Breyer-KohansalRosa FanerValentina Agnese FerraroAndreja SajnicMaribel Casas et al.

Het belang van de oceaan voor onze gezondheid : rapport van de Ostend Working Group on Ocean and Human Health

Gert EveraertRaf AertsJan BourgoisAnn BuysseAdrian CovaciMaarten De RijckeEveline DiopereAlexander HooybergCarl LachatLies Lahousse et al.

Het belang van frailty bij volwassenen met longziekten

A4 Journal Article in BLOEDVATEN HART LONGEN

Impact of frailty on the effectiveness and safety of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation : a nationwide cohort study

Maxim GrymonprezMirko PetrovicTine De BackerStephane SteurbautLies Lahousse

A1 Journal Article in EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES

Implementing primary care concepts in higher education : a mixed method study in Flanders (Belgium)

Lotte VannesteSam PlessSandra MartinEmily VerteRoy RemmenPauline BoeckxstaensPeter PypeReini HaveralsDagje BoeykensDominique Van de Velde et al.

A1 Journal Article in BMC PRIMARY CARE

Knowing me, knowing you-lessons learned from three European studies on European medicines agency's risk communication

Ella van VlietAnna Birna AlmasdottirShahab AbtahiChristos KontogiorgisElita PoplavskaMitja KosInes Ribeiro-VazJuan ErvitiLies LahousseTeresa Leonardo Alves

Lung-function trajectories : relevance and implementation in clinical practice

Erik MelénRosa FanerJames P. AllinsonDinh BuiAndrew BushAdnan CustovicJudith Garcia-AymerichStefano GuerraRobab Breyer-KohansalJenny Hallberg et al.

A1 Journal Article in LANCET

Medication adherence to inhalation therapy and the risk of COPD exacerbations : a systematic review with meta-analysis

Delphine VauterinFrauke Van VaerenberghMaxim GrymonprezAnna VanoverscheldeLies Lahousse

A1 Journal Article in BMJ OPEN RESPIRATORY RESEARCH

Overweight and dysanapsis in childhood asthma

Editorial material

Pharmacogenetic effects on clusters of lung function decline

Lies LahousseXander BertelsAndré UitterlindenGuy BrusselleBruno Stricker

Potentially inappropriate prescribing in multimorbid and polymedicated older adults with AF : a systematic review and meta-analysis

Cheïma AmrouchDelphine VauterinSouad AmrouchMaxim GrymonprezLu DaiCecilia DamianoAmaia Calderón-LarrañagaLies LahousseDirk De BacquerGregory Y. H. Lip et al.

A1 Journal Article in DRUGS & AGING

Respiratory epidemiology in the advancement of precision medicine

Xander BertelsLies LahousseGuy Brusselle

Rhinitis control and medication use in a real-world sample of patients with persistent rhinitis or rhinosinusitis : a community pharmacy study

Sophie ScheireSophie GermonpréEls MehuysInge Van TongelenAn De SutterStephane SteurbautThierry Van HeesSophie DemarcheLies LahoussePhilippe Gevaert et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

The AGE-RAGE axis associates with chronic pulmonary diseases and smoking in the Rotterdam study

Tianqi LuLies LahousseSara WijnantJinluan ChenGuy BrusselleMandy van HoekM. Carola Zillikens

A1 Journal Article in RESPIRATORY RESEARCH

The impact of polypharmacy on the effectiveness and safety of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation

Maxim GrymonprezMirko PetrovicTine De BackerStephane SteurbautLies Lahousse

A1 Journal Article in THROMBOSIS AND HAEMOSTASIS

Understanding the aetiology of lung function impairment : the crucial role of age of onset

Xander BertelsLies Lahousse

Editorial material

2023

Advanced glycation end products (AGEs) in relation to COPD and lung function : the Rotterdam Study

Tianqi LuLies LahousseSara WijnantJinluan ChenGuy BrusselleMandy Van HoekM. Carola Zillikens

Association of a polygenic risk score for chronic obstructive pulmonary disease with lung function across the lifespan

Natalia Hernandez-PachecoAnna KilanowskiAshish KumarJohn A. CurtinNuria OlveraSara KressXander BertelsLies LahousseLaxmi BhattaRaquel Granell et al.

Barriers and facilitators for adherence to direct oral anticoagulants in patients with atrial fibrillation : a qualitative approach

Andreas CapiauMaxim GrymonprezSophie ScheireYenna FauteLies LahousseEls MehuysTine De BackerKoen Boussery

A1 Journal Article in THROMBOSIS RESEARCH

Building an understanding of goal-oriented care through the experiences of people living with chronic conditions

Dagje BoeykensLara DecosterDorine LenoirAn De SutterReini HaveralsLies LahoussePeter PypeDominique Van de VeldePauline BoeckxstaensPatricia De Vriendt

A1 Journal Article in PATIENT EDUCATION AND COUNSELING

Clinical outcomes in patients with atrial fibrillation and a history of falls using non-vitamin K antagonist oral anticoagulants : a nationwide cohort study

Maxim GrymonprezMirko PetrovicTine De BackerStephane SteurbautLies Lahousse

A2 Journal Article in IJC HEART & VASCULATURE

Comparing the risk of dementia in subjects with atrial fibrillation using non-vitamin K antagonist oral anticoagulants versus vitamin K antagonists : a Belgian nationwide cohort study

Maxim GrymonprezMirko PetrovicTine De BackerM Arfan IkramStephane SteurbautLies Lahousse

A1 Journal Article in AGE AND AGEING

COPD and multimorbidity : recognising and addressing a syndemic occurrence

Leonardo M. FabbriBartolome R. CelliAlvar AgustiGerard J. CrinerMark T. DransfieldMiguel DivoJamuna K. KrishnanLies LahousseMaria Montes de OcaSundeep S. Salvi et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Digitale transformatie, big data en kunstmatige intelligentie

Marc AcheroyLuc BonteRose BruffaertsHugo De ManErol GelenbeLies LahousseBenoit MacqHendrik Van BrusselValentin Van Den BalckJoos Vandewalle et al.

Bookchapter in Betrokken op de samenleving : de academies en de uitdagingen van een complexe wereld

Do the lockdown-imposed changes in a wastewater treatment plant catchment's socio-demographics impact longitudinal temporal trends in psychoactive pharmaceutical use?

Tim BoogaertsMaarten QuireynsHans De LoofXander BertelsNatan Van WichelenBram PussigJan SaevelsLies LahoussePauline BonmariageWouter Hamelinck et al.

A1 Journal Article in SCIENCE OF THE TOTAL ENVIRONMENT

European Respiratory Society statement on frailty in adults with chronic lung disease

Christian R. OsadnikLisa J. BrightonChris BurtinMatteo CesariLies LahousseWill D. C. ManAlessandra MarengoniAndreja SajnicJonathan P. SingerLies ter Beek et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Factors influencing the choice of and adherence to oral anticoagulants in patients with atrial fibrillation: a Belgian nationwide cohort study

Maxim GrymonprezTine De BackerAndreas CapiauDelphine VauterinEls MehuysKoen BousseryStephane SteurbautLies Lahousse

Frailty transitions in older persons with lung function impairment : a population-based study

Sara WijnantElizabeth BenzAnnemarie I LuikFernando RivadeneiraTrudy VoortmanGuy BrusselleLies Lahousse

A1 Journal Article in JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

General health and working conditions of Flemish primary care professionals

Veerle BuffelMuhammed Mustafa SirimsiPatricia De VriendtDominique Van de VeldeLies Lahousse

A1 Journal Article in BMC PRIMARY CARE

How do people living with chronic conditions and their informal caregivers experience primary care? A phenomenological‐hermeneutical study

Dagje BoeykensMuhammed Mustafa SirimsiLotte TimmermansMaja Lopez HartmannSibyl AnthierensHans De LoofKristel De VliegherVeerle FoulonIne HuybrechtsLies Lahousse et al.

A1 Journal Article in JOURNAL OF CLINICAL NURSING

Impact of P-glycoprotein and CYP3A4-interacting drugs on clinical outcomes in patients with atrial fibrillation using non-vitamin K antagonist oral anticoagulants : a nationwide cohort study

Maxim GrymonprezLaura CarnoyAndreas CapiauKoen BousseryEls MehuysTine L. De BackerStephane SteurbautLies Lahousse

A1 Journal Article in EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY

Impact of triple therapy on mortality in COPD

Thibaud SoumagneMaeva ZysmanDilek KaradoganLies LahousseAlexander G. Mathioudakis

A2 Journal Article in BREATHE

In-hospital antibiotic use for severe chronic obstructive pulmonary disease exacerbations : a retrospective observational study

Anna VanoverscheldeChloë Van HoeyFranky BuyleNadia Den BlauwenPieter DepuydtEva Van BraeckelLies Lahousse

A1 Journal Article in BMC PULMONARY MEDICINE

Long-term comparative effectiveness and safety of dabigatran, rivaroxaban, apixaban and edoxaban in patients with atrial fibrillation : a nationwide cohort study

Maxim GrymonprezTine De BackerXander BertelsStephane SteurbautLies Lahousse

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Methods to assess COPD medications adherence in healthcare databases : a systematic review

Delphine VauterinFrauke Van VaerenberghAnna VanoverscheldeJennifer K. QuintKatia VerhammeLies Lahousse

A1 Journal Article in EUROPEAN RESPIRATORY REVIEW

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Nick ShrineAbril G. IzquierdoJing ChenRichard PackerRobert J. HallAnna L. GuyattChiara BatiniRebecca J. ThompsonChandan PavuluriVidhi Malik et al.

A1 Journal Article in NATURE GENETICS

Non-vitamin K antagonist oral anticoagulants (NOACs) versus warfarin in patients with atrial fibrillation using P-gp and/or CYP450-interacting drugs : a systematic review and meta-analysis

Maxim GrymonprezKevin VansprangheStephane SteurbautTine De BackerLies Lahousse

A1 Journal Article in CARDIOVASCULAR DRUGS AND THERAPY

Novel genetic variants associated with inhaled corticosteroid treatment response in older adults with asthma

Alberta L. WangLies LahousseAmber DahlinAhmed Edris MohamedMichael McGeachieSharon M. LutzJoanne E. SordilloGuy BrusselleJessica Lasky-SuScott T. Weiss et al.

A1 Journal Article in THORAX

Optimal adherence threshold to non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation to reduce the risk of thromboembolism and death

Maxim GrymonprezS. SteurbautAndreas CapiauDelphine VauterinFrauke Van VaerenberghEls MehuysKoen BousseryTine De BackerLies Lahousse

Oral corticosteroid use and sarcopenia-related traits in older people with chronic airway disease : a population-based study

Elizabeth BenzLies LahousseJohnmary Tochukwu ArinzeSara WijnantMaria de RidderFernando RivadeneiraGuy BrusselleBruno H. Stricker

A1 Journal Article in ERJ OPEN RESEARCH

Pharmacological treatment of patients with respiratory diseases : exploring opportunities for clinical pharmaceutical interventions

Anna VanoverscheldeLies Lahousse

Phenotyping asthma with airflow obstruction in middle-aged and older adults : a CADSET clinical research collaboration

Xander BertelsAhmed Edris MohamedJudith Garcia-AymerichRosa FanerHowraman MeteranTorben SigsgaardPeter AlterClaus VogelmeierNuria OlveraNazanin Zounemat Kermani et al.

A1 Journal Article in BMJ OPEN RESPIRATORY RESEARCH

Predictors and associations of the persistent airflow limitation phenotype in asthma : a post-hoc analysis of the ATLANTIS study

Tessa M. KoleElise Vanden BergheMonica KraftJudith M. VonkMartijn C. NawijnSalman SiddiquiKai SunLeonardo M. FabbriKlaus F. RabeKian Fan Chung et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Rational oral anticoagulant use in patients with atrial fibrillation

Maxim GrymonprezLies LahousseStephane Steurbout

Smoking, blood DNA methylation sites and lung cancer risk

Arce Domingo-RellosoRoby JoehanesZulema Rodriguez-HernandezLies LahousseKarin HaackM. Daniele FallinMiguel Herreros-MartinezJason G. UmansLyle G. BestTianxiao Huan et al.

A1 Journal Article in ENVIRONMENTAL POLLUTION

Smoking-related dysregulation of plasma circulating microRNAs : the Rotterdam study

Irma KarabegovicSilvana C. E. MaasYu ShuaiM. Arfan IkramBruno StrickerJoachim AertsGuy BrusselleLies LahousseTrudy VoortmanMohsen Ghanbari

A1 Journal Article in HUMAN GENOMICS

The role of community pharmacists in primary and secondary prevention of skin cancer : an evaluation of a Flemish skin cancer prevention campaign

Kristiaan ProesmansFrauke Van VaerenberghLies Lahousse

A1 Journal Article in BMC PUBLIC HEALTH

Time series modelling for wastewater-based epidemiology of COVID-19 : a nationwide study in 40 wastewater treatment plants of Belgium, February 2021 to June 2022

Xander BertelsSven HanoteauxRaphael JanssensHadrien MalouxBavo VerhaegenPeter DelputteTim BoogaertsAlexander L.N. van NuijsDelphine BrognaCatherine Linard et al.

A1 Journal Article in SCIENCE OF THE TOTAL ENVIRONMENT

Trends in oral anticoagulant use in patients with atrial fibrillation in Belgium from 2013 to 2019 : a nationwide cohort study

Maxim GrymonprezTine De BackerAndreas CapiauDelphine VauterinEls MehuysKoen BousseryStephane SteurbautLies Lahousse

A1 Journal Article in BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Trends in outpatient azithromycin prescribing in respiratory diseases

Victor PeraHelen PanenMaria A. J. De RidderLies LahousseGuy BrussellePeter R. RijnbeekKatia Verhamme

What is frailty?

Lisa Jane BrightonSuzanne LareauMatthew MaddocksChristian OsadnikLies LahousseAnnemarie LeeJennifer AllisonJonathan SingerDmitry RozenbergWilliam D. C. Man et al.

Editorial material

Which COPD patients benefit from beta-blocker therapy?

Editorial material

Will the implementation process for goal-oriented primary care succeed? A qualitative study investigating five perceived attributes of goal-oriented care

Ine HuybrechtsAnja DeclercqEmily VertéPauline BoeckxstaensPeter RaeymaeckersSibyl AnthierensDominique Van de VeldeAn De SutterPatricia De VriendtLies Lahousse et al.

A1 Journal Article in SOCIAL SCIENCE & MEDICINE

2022

Adherence and persistence to oral anticoagulants in patients with atrial fibrillation : a Belgian nationwide cohort study

Maxim GrymonprezAndreas CapiauStephane SteurbautEls MehuysKoen BousseryTine De BackerLies Lahousse

A1 Journal Article in FRONTIERS IN CARDIOVASCULAR MEDICINE

Anti–interleukin-5 therapy is associated with attenuated lung function decline in severe eosinophilic asthma patients from the Belgian Severe Asthma Registry

Sophie GraffGuy BrusselleShane HanonCarine SohyLieven DupontRudy PecheAlain MichilsCharles PiletteGuy JoosLies Lahousse et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Changes in lung function in European adults born between 1884 and 1996 and implications for the diagnosis of lung disease : a cross-sectional analysis of ten population-based studies

James P AllinsonShoaib AfzalYunus ÇolakDebbie JarvisHelena BackmanMaarten van den BergeH Marike BoezenMarie-Kathrin BreyerRobab Breyer-KohansalGuy Brusselle et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Community pharmacist counseling improves adherence and asthma control : a nationwide study

Barbara PutmanLouise CouckeAnna VanoverscheldeEls MehuysLies Lahousse

A1 Journal Article in BMC HEALTH SERVICES RESEARCH

Effectiviteit en veiligheid van directe orale anticoagulantia bij patiënten met voorkamerfibrillatie

Andreas CapiauMaxim GrymonprezKoen BousseryLies LahousseTine De Backer

A2 Journal Article in TIJDSCHRIFT VOOR CARDIOLOGIE

Evaluating the impact of COVID-19 countermeasures on alcohol consumption through wastewater-based epidemiology : a case study in Belgium

Tim BoogaertsXander BertelsBram PussigMaarten QuireynsLouis ToeboschNatan Van WichelenCatalina DumitrascuCatherina MatheïLies LahousseBert Aertgeerts et al.

A1 Journal Article in ENVIRONMENT INTERNATIONAL

Factors influencing SARS-CoV-2 RNA concentrations in wastewater up to the sampling stage : a systematic review

Xander BertelsPhaedra DemeyerSiel Van den BogaertTim BoogaertsAlexander L.N. van NuijsPeter DelputteLies Lahousse

A1 Journal Article in SCIENCE OF THE TOTAL ENVIRONMENT

From theory to an understanding on how primary care providers and managers operationalize goal-oriented care in three international primary care settings

Dagje BoeykensPatricia De VriendtAn De SutterAgnes GrudniewiczLies LahoussePeter PypeCarolyn Steele GrayDominique Van de VeldePauline Boeckxstaens

Genetic associations and architecture of asthma-chronic obstructive pulmonary disease overlap

Catherine JohnAnna L. GuyattNick ShrineRichard PackerThorunn A. OlafsdottirJiangyuan LiuLystra P. HaydenSu H. ChuJukka T. KoskelaJian’an Luan et al.

A1 Journal Article in CHEST

Goal-oriented care : an understanding on how primary healthcare professionals operationalize goal-oriented care in three international settings (Ghent, Vermont, and Ottawa)

Dagje BoeykensPatricia De VriendtAn De SutterAgnes GrudniewizcLies LahoussePeter PypeCarolyn Steele GrayDominique Van de VeldePauline Boeckxstaens

Goal-oriented care : operationalizing the theoretical concept by insights of cases in Ghent, Vermont, and Ottawa

Dagje BoeykensPatricia De VriendtAnne De SutterAgnes GrudniewiczLies LahoussePeter PypeCarolyn Steele GrayDominique Van de VeldePauline Boeckxstaens

Goal-oriented care for patients with chronic conditions or multimorbidity in primary care : a scoping review and concept analysis

Dagje BoeykensPauline BoeckxstaensAn De SutterLies LahoussePeter PypePatricia De VriendtDominique Van de Velde

A1 Journal Article in PLOS ONE

Impact of P-glycoprotein and/or CYP3A4-interacting drugs on effectiveness and safety of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation : a meta-analysis

Maxim GrymonprezKevin VansprangheAndreas CapiauKoen BousseryStephane SteurbautLies Lahousse

A1 Journal Article in BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Lung function impairment in relation to cognition and vascular brain lesions : the Rotterdam Study

Tian XiaoSara WijnantIsabelle van der VelpenNatalie TerzikhanLies LahousseM. Kamran IkramMeike W VernooijGuy BrusselleM. Arfan Ikram

A1 Journal Article in JOURNAL OF NEUROLOGY

Non-vitamin K antagonist oral anticoagulants (NOACs) versus warfarin in patients with atrial fibrillation and (morbid) obesity or low body weight : a systematic review and meta-analysis

Maxim GrymonprezTine De BackerStephane SteurbautKoen BousseryLies Lahousse

A1 Journal Article in CARDIOVASCULAR DRUGS AND THERAPY

Optimization and application of a multiplex digital PCR assay for the detection of SARS-CoV-2 variants of concern in Belgian influent wastewater

Tim BoogaertsSiel Van den BogaertLaura A. E. Van PoelvoordeDiala El MasriNaomi De RoeckNancy H. C. RoosensMarie LesenfantsLies LahousseKoenraad Van HoordeAlexander L. N. van Nuijs et al.

A1 Journal Article in VIRUSES-BASEL

Pharmacogenetics of inhaled corticosteroids and exacerbation risk in adults with asthma

Ahmed Edris MohamedEmmely de RoosMichael J. McGeachieKatia VerhammeGuy BrusselleKelan G. TantisiraCarlos IribarrenMeng LuAnn Chen WuBruno H. Stricker et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Precision medicine from a citizen perspective : a survey of public attitudes towards pharmacogenomics in Flanders

Ahmed Edris MohamedEvi CallierLies Lahousse

A1 Journal Article in BMC MEDICAL GENOMICS

Pulmonary function and blood DNA methylation a multiancestry epigenome-wide association meta-analysis

Mikyeong LeeTianxiao HuanDaniel L. McCartneyGeetha ChittoorMaaike de VriesLies LahousseJennifer N. NguyenJennifer A. BrodyJuan Castillo-FernandezNatalie Terzikhan et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sarcopenia, systemic immune-inflammation index and all-cause mortality in middle-aged and older people with COPD and asthma : a population-based study

Elizabeth BenzSara WijnantKaterina TrajanoskaJohnmary Tochukwu ArinzeEmmely de RoosMaria de RidderRoss WilliamsFrank van RooijKatia M. C. VerhammeM. Arfan Ikram et al.

A1 Journal Article in ERJ OPEN RESEARCH

SARS-CoV-2 surveillance in Belgian wastewaters

Raphael JanssensSven HanoteauxHadrien MalouxSofieke KlamerValeska LaisnezBavo VerhaegenCatherine LinardLies LahoussePeter DelputteMatthieu Terwagne et al.

A1 Journal Article in VIRUSES-BASEL

Serum immunoglobulins, pneumonia risk, and lung function in middle-aged and older individuals : a population-based cohort study

Samer R. KhanAnna VanoverscheldeLies LahousseRobin P. PeetersP. Martin van HagenGuy BrusselleLayal ChakerVirgil A. S. H. Dalm

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

The implementation of risk minimization measures to prevent teratogenic pregnancy outcomes related to oral retinoid and valproate use in Belgium

Xander BertelsEls MehuysKoen BousseryLies Lahousse

A1 Journal Article in ACTA CLINICA BELGICA

Validation of clinical COPD phenotypes for prognosis of long-term mortality in Swedish and Dutch cohorts

S. GagatekSara WijnantB. StallbergK. LisspersGuy BrusselleX. ZhouM. HasselgrenS. MontgomeryiJ. SundhjC. Janson et al.

A1 Journal Article in COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Worldwide trends in oral anticoagulant use in patients with atrial fibrillation from 2010 to 2018 : a systematic review and meta-analysis

Maxim GrymonprezCynthia SimoensStephane SteurbautTine De BackerLies Lahousse

A1 Journal Article in EUROPACE

2021

A roadmap towards precision medicine in asthma

Ahmed Edris MohamedLies Lahousse

A systematic analysis of protein-altering exonic variants in chronic obstructive pulmonary disease

Matthew MollVictoria E. JacksonBing YuMegan L. GroveStephanie J. LondonSina A. GharibTraci M. BartzColleen M. SitlaniJosee DupuisGeorge T. O'Connor et al.

A1 Journal Article in AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

An alternative approach for bioanalytical assay optimization for wastewater-based epidemiology of SARS-CoV-2

Tim BoogaertsLotte JacobsNaomi De RoeckSiel Van den BogaertBert AertgeertsLies LahousseAlexander L. N. van NuijsPeter Delputte

A1 Journal Article in SCIENCE OF THE TOTAL ENVIRONMENT

Appropriateness of direct oral anticoagulant dosing in patients with atrial fibrillation according to the drug labelling and the EHRA Practical Guide

Andreas CapiauTine De BackerMaxim GrymonprezLies LahousseInge Van TongelenEls MehuysKoen Boussery

A1 Journal Article in INTERNATIONAL JOURNAL OF CARDIOLOGY

Benefits of angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers on progression of emphysema and lung function decline

Xander BertelsLies Lahousse

Editorial material

Comparison of cerebral blood flow in subjects with and without chronic obstructive pulmonary disease from the population-based Rotterdam Study

Sara WijnantDaniel BosGuy BrusselleMaxim GrymonprezErnst RietzschelMeike W. VernooijNatalie TerzikhanLies Lahousse

A1 Journal Article in BMJ OPEN

Determinants of poor inhaler technique and poor therapy adherence in obstructive lung diseases : a cross-sectional study in community pharmacies

Anna VanoverscheldePaulien van der WelBarbara PutmanLies Lahousse

A1 Journal Article in BMJ OPEN RESPIRATORY RESEARCH

Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium

Merel JacobsLies LahousseHannelore Van EeckhoutteSara WijnantJoris DelangheGuy BrusselleKen Bracke

A1 Journal Article in ERJ OPEN RESEARCH

Effect of beta-blockers on the risk of COPD exacerbations according to indication of use : the Rotterdam Study

Leila KarimiLies LahoussePhebe De NockerBruno H. StrickerGuy BrusselleKatia Verhamme

A1 Journal Article in ERJ OPEN RESEARCH

Epigenome-wide association study on diffusing capacity of the lung

Natalie TerzikhanHanfei XuAhmed Edris MohamedKen BrackeFien VerhammeBruno H. C. StrickerJosée DupuisLies LahousseGeorge T. O'ConnorGuy Brusselle

A1 Journal Article in ERJ OPEN RESEARCH

Factors associated with treatment response to inhaled corticosteroids : insights from WTC-exposed and chronic users

Barbara PutmanLies LahousseMichael D. Weiden

Goal-oriented care : a concept analysis

Dagje BoeykensPauline BoeckxstaensAn De SutterLies LahoussePeter PypePatricia De VriendtDominique Van de Velde

Incidence and predictors of asthma exacerbations in middleaged and older adults : the Rotterdam Study

Emmely de RoosLies LahousseKatia VerhammeGert-Jan BraunstahlJohannes J. C. C. M. in 't VeenBruno H. StrickerGuy Brusselle

A1 Journal Article in ERJ OPEN RESEARCH

Lung function decline before and after treatment of World Trade Center associated obstructive airways disease with inhaled corticosteroids and long-acting beta agonists

David G. GoldfarbBarbara PutmanLies LahousseRachel Zeig-OwensBrandon M. VaethTheresa SchwartzCharles B. HallDavid J. PrezantMichael D. Weiden

A1 Journal Article in AMERICAN JOURNAL OF INDUSTRIAL MEDICINE

Lung function impairment and the risk of incident dementia : the Rotterdam study

Tian XiaoSara WijnantSilvan LicherNatalie TerzikhanLies LahousseM. Kamran IkramGuy BrusselleM. Arfan Ikram

A1 Journal Article in JOURNAL OF ALZHEIMERS DISEASE

Macrolide-associated ototoxicity : a cross-sectional and longitudinal study to assess the association of macrolide use with tinnitus and hearing loss

Anna VanoverscheldeBerthe C. OosterlooNelly F. LyM. Arfan IkramAndre GoedegebureBruno H. StrickerLies Lahousse

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Monoclonal antibodies in type 2 asthma : an updated network meta-analysis

Ahmed Edris MohamedLies Lahousse

A1 Journal Article in MINERVA MEDICA

Niet-vitamine K-antagonist orale anticoagulantia bij oudere patiënten met voorkamerfibrillatie

Maxim GrymonprezStephane SteurbautTine De BackerMirko PetrovicLies Lahousse

A2 Journal Article in TIJDSCHRIFT VOOR CARDIOLOGIE

Personalizing oral corticosteroid dose in severe COPD exacerbations

Editorial material

Pharmacogenetics in clinical practice : current level of knowledge among Flemish physicians and pharmacists

Ahmed Edris MohamedAnna VanoverscheldePranvera BushajFilip Van NieuwerburghLies Lahousse

A1 Journal Article in PHARMACOGENOMICS JOURNAL

Phenotyping adults with impaired pulmonary function in the era of precision medicine

Sara WijnantGuy BrusselleLies LahousseErnst Rietzschel

Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function

Tianzhong YangVictoria E. JacksonV Smith, AlbertHan ChenTraci M. BartzColleen M. SitlaniBruce M. PsatySina A. GharibGeorge T. O'ConnorJosee Dupuis et al.

A1 Journal Article in SCIENTIFIC REPORTS

Sarcopenia in older people with chronic airway diseases : the Rotterdam study

Elizabeth BenzKaterina TrajanoskaJosje D. SchoufourLies LahousseEmmely de RoosNatalie TerzikhanCarolina Medina-GomezKatia VerhammeRoss WilliamsBruno H. Stricker et al.

A1 Journal Article in ERJ OPEN RESEARCH

Teratogeniciteit bij orale retinoïden en valproaat

Xander BertelsLies Lahousse

Article in a magazine

The ALPACA study : (in)appropriate LAMA prescribing in asthma : a cohort analysis

E. J. BaanC. E. HoeveM. De RidderL. DemoenLies LahousseGuy BrusselleKatia Verhamme

A1 Journal Article in PULMONARY PHARMACOLOGY & THERAPEUTICS

The impact of underweight and obesity on outcomes in anticoagulated patients with atrial fibrillation : a systematic review and meta‐analysis on the obesity paradox

Maxim GrymonprezAndreas CapiauTine De BackerStephane SteurbautKoen BousseryLies Lahousse

A1 Journal Article in CLINICAL CARDIOLOGY

The interaction of cognitive and brain reserve with frailty in the association with mortality : an observational cohort study

Jende L. ZijlmansSander LamballaisLies LahousseMeike VernooijM. Kamran IkramM. Arfan IkramI Luik, Annemarie

A1 Journal Article in LANCET HEALTHY LONGEVITY

Voorkamerfibrillatie en niet-vitamine K-antagonist orale anticoagulantia : van klinische studies tot gebruik in de dagelijkse praktijk

Andreas CapiauMaxim GrymonprezTine De BackerSofie GevaertKoen BousseryLies Lahousse

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

2020

A cross-omics integrative study of metabolic signatures of chronic obstructive pulmonary disease

Ivana ProkicLies LahousseMaaike de VriesJun LiuMarita KalaojaJudith M. VonkDiana van der PlaatCleo van DiemenAshley van der SpekAlexandra Zhernakova et al.

A1 Journal Article in BMC PULMONARY MEDICINE

A pragmatic randomized controlled trial to improve inhaler technique using mHealth

Anna VanoverscheldePaulien van der WelBarbara PutmanLies Lahousse

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Beliefs and preferences regarding biological treatments for severe asthma

Andras BikovIpek Kivilcim OguzulgenIlaria BaiardiniMarco ContoliAlexander EmelyanovOmar FassioJuan Carlos IvancevichIgor KaidashevKrzysztof KowalMarina Labor et al.

A1 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

Blood eosinophil level and lung function trajectories : cross-sectional and longitudinal studies in European cohorts

Ida MogensenJudith M. VonkSara WijnantXingwu ZhouH. Marike BoezenGuy BrusselleLies LahousseChrister JansonAndrei Malinovschi

A1 Journal Article in ERJ OPEN RESEARCH

Change in blood eosinophils following treatment with inhaled corticosteroids may predict long-term clinical response in COPD

Alexander G. MathioudakisAndras BikovPhilip FodenLies LahousseGuy BrusselleDave SinghJorgen Vestbo

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Chronic obstructive pulmonary disease and related phenotypes : polygenic risk scores in population-based and case-control cohorts

Matthew MollPhuwanat SakornsakolpatNick ShrineBrian D. HobbsDawn L. DeMeoCatherine JohnAnna L. GuyattMichael J. McGeachieSina A. GharibMa'en Obeidat et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Current developments and future directions in COPD

Alexander G. MathioudakisLowie E. G. W. VanfleterenLies LahousseAndrew HighamJames P. AllinsonCarolina GoteraDina ViscaDave SinghAntonio Spanevello

A1 Journal Article in EUROPEAN RESPIRATORY REVIEW

Dyspnea and inhaled corticosteroid and long-acting β-agonist therapy in an occupational cohort : a longitudinal study

Barbara PutmanLies LahousseAnkura SinghRachel Zeig-OwensCharles B. HallMelissa J. FazzariTheresa SchwartzMayris P. WebberHillel W. CohenDavid J. Prezant et al.

A1 Journal Article in ANNALS OF THE AMERICAN THORACIC SOCIETY

Effectiveness and safety of oral anticoagulants in older patients with atrial fibrillation : a systematic review and meta-analysis

Maxim GrymonprezStephane SteurbautTine De BackerMirko PetrovicLies Lahousse

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

ERS International Congress, Madrid, 2019 : highlights from the airway diseases, asthma and COPD assembly

Lies LahousseSara Cuevas-OcanaPauline FlajoletAlexander G. MathioudakisMelissa McDonnellThomas BahmerLena UllerFlorence SchleichSergio Dortas JuniorMarco Idzko et al.

A1 Journal Article in ERJ OPEN RESEARCH

Factors predicting treatment of World Trade Center-related lung injury : a longitudinal cohort study

Barbara PutmanLies LahousseDavid G. GoldfarbRachel Zeig-OwensTheresa SchwartzAnkura SinghBrandon VaethCharles B. HallElizabeth A. LancetMayris P. Webber et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH

Impact of a single non-sex-related stroke risk factor on atrial fibrillation and oral anticoagulant outcomes : a systematic review and meta-analysis

Maxim GrymonprezStephane SteurbautAn De SutterLies Lahousse

A2 Journal Article in OPEN HEART

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

Jun LiuLies LahousseMichel G NivardMariska BotLianmin ChenJan Bert van KlinkenCarisha S ThesingMarian BeekmanErik Ben van den AkkerRoderick C Slieker et al.

A1 Journal Article in NATURE MEDICINE

The global significance of PRISm : how data from low- and middle-income countries link physiology to inflammation

Sara WijnantLies LahousseGuy Brusselle

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

The obesity paradox in lung cancer : associations with body size versus body shape

F. H. ArdeschR. RuiterM. MulderLies LahousseB. H. C. StrickerJ. C. Kiefte-de Jong

A1 Journal Article in FRONTIERS IN ONCOLOGY

Trajectory and mortality of preserved ratio impaired spirometry : the Rotterdam Study

Sara WijnantEmmely de RoosMaryam KavousiBruno Hugo StrickerNatalie TerzikhanLies LahousseGuy Brusselle

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

2019

Adherence to controller therapy in chronic obstructive pulmonary disease : real life setting

Leila KarimiEsme J BaanTiana GeeraerdJohan Van der LeiBruno HC StrickerGuy BrusselleLies LahousseKatia M Verhamme

Adherence trajectories in asthmatic patients

Esme BaanLeila KarimiAstrid HeeremansGuy BrusselleMiriam SturkenboomHettie M JanssensLies LahousseJohan C de JongsteKatia Verhamme

Association of alcohol consumption with allergic disease and asthma : a multi-centre Mendelian randomization analysis

Tea SkaabyTuomas O. KilpelainenAmy E. TaylorYuvaraj MahendranAndrew WongTarunveer S. AhluwaliaLavinia PaternosterStella TrompetDavid J. StottClaudia Flexeder et al.

A1 Journal Article in ADDICTION

Atherosclerotic calcification in major vessel beds in chronic obstructive pulmonary disease : the Rotterdam Study

Lies LahousseDaniel BosSara WijnantMaryam KavousiBruno H. StrickerAad van der LugtMeike W. VernooijGuy Brusselle

A1 Journal Article in ATHEROSCLEROSIS

Beta(2)-adrenergic receptor (ADRB2) gene polymorphisms and risk of COPD exacerbations : the Rotterdam study

Leila KarimiLies LahousseMohsen GhanbariNatalie TerzikhanAndre G. UitterlindenJohan van der LeiGuy BrusselleBruno H. StrickerKatia Verhamme

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Chronic Airway Diseases Early Stratification (CADSET) : a new ERS clinical research collaboration

Alvar AgustiRosa FanerGavin DonaldsonElise HeuvelinRobab Breyer-KohansalErik MelenAnke H Maitland-van der ZeeJorgen VestboJames P AllinsonLowie EGW Vanfleteren et al.

Editorial material

Chronic obstructive pulmonary disease and the development of atrial fibrillation

Maxim GrymonprezVincent VakaetMaryam KavousiBruno H StrickerM Arfan IkramJan HeeringaOscar H FrancoGuy BrusselleLies Lahousse

A1 Journal Article in INTERNATIONAL JOURNAL OF CARDIOLOGY

DNA methylation is associated with lung function in never smokers

Maaike de VriesIvana NedeljkovicDiana A. van der PlaatAlexandra ZhernakovaLies LahousseGuy BrusselleNajaf AminCornelia M. van DuijnJudith M. VonkH. Marike Boezen

A1 Journal Article in RESPIRATORY RESEARCH

Endoscopic management of biliary leaks : a systematic review with meta-analysis

Kenny VlaemynckLies LahousseAude VanlanderHubert PiessevauxPieter Hindryckx

A1 Journal Article in ENDOSCOPY

Epigenetic targets for lung diseases

Editorial material

Epigenome-wide association studies in asthma : a systematic review

Ahmed Edris MohamedHerman T den DekkerErik MelénLies Lahousse

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

Phuwanat SakornsakolpatDmitry ProkopenkoMaxime LamontagneNicola F ReeveAnna L GuyattVictoria E JacksonNick ShrineDandi QiaoTraci M BartzDeog Kyeom Kim et al.

A1 Journal Article in NATURE GENETICS

Lifetime risk and multimorbidity of non-communicable diseases and disease-free life expectancy in the general population : a population-based cohort study

Silvan LicherAlis HeshmatollahKimberly D van der WillikBruno HCh StrickerRikje RuiterEmmely W de RoosLies LahoussePeter J KoudstaalAlbert HofmanLana Fani et al.

A1 Journal Article in PLOS MEDICINE

Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population

Diana A van der PlaatJudith M VonkLies LahousseKim de JongAlen FaizIvana NedeljkovicNajaf AminCleo C van DiemenGuy BrusselleYohan Bosse et al.

A1 Journal Article in BMC PULMONARY MEDICINE

Low serum IgA and airway injury in World Trade Center-exposed firefighters : a 17-year longitudinal study

Barbara PutmanLies LahousseRachel Zeig-OwensAnkura SinghCharles B HallYang LiuTheresa SchwartzDavid GoldfarbMayris P WebberDavid J Prezant et al.

A1 Journal Article in THORAX

Monoclonal antibodies in type 2 asthma : a systematic review and network meta-analysis

Ahmed Edris MohamedSilke De FeyterTania MaesGuy JoosLies Lahousse

A1 Journal Article in RESPIRATORY RESEARCH

Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course

Herman T den DekkerKimberley BurrowsJanine F FelixLucas A SalasIvana NedeljkovicJin YaoSheryl L Rifas-ShimanCarlos Ruiz-ArenasN AminMariona Bustamante et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression

Diana van Der PlaatJudith M VonkNatalie TerzikhanKim de JongMaaike de VriesSacha La Bastide-van GemertCleo C van DiemenLies LahousseGuy BrusselleIvana Nedeljkovic et al.

A1 Journal Article in HUMAN MOLECULAR GENETICS

Omega-3 fatty acids and genome-wide interaction analyses reveal DPP10-pulmonary function association

Jiayi XuNathan C GaddisTraci M BartzRuixue HouAni W ManichaikulNathan PankratzAlbert V SmithFangui SunNatalie TerzikhanChristina A Markunas et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Prevalence of asthma and COPD and blood eosinophil count in a middle-aged Belgian population

Sara WijnantLies LahousseMarc De BuyzereGuy BrusselleErnst Rietzschel

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Rhinitis medication use in patients with persistent rhinitis: Belgian cross-sectional study with historical control

Sophie ScheireS. GermonpreEls MehuysThierry ChristiaensAn De SutterInge Van TongelenS. DemarcheT. Van HeesLies LahoussePhilippe Gevaert et al.

Sarcopenia in COPD : a systematic review and meta-analysis

Elizabeth BenzKaterina TrajanoskaLies LahousseJosje D SchoufourNatalie TerzikhanEmmely de RoosGerdien B de JongeRoss WilliamsOscar H FrancoGuy Brusselle et al.

A1 Journal Article in EUROPEAN RESPIRATORY REVIEW

Sphincterotomy alone appears sufficient for the treatment of bile leaks : reply to Chandra et al.

Kenny VlaemynckLies LahousseAude VanlanderHubert PiessevauxPieter Hindryckx

A1 Journal Article in ENDOSCOPY

The association between dietary protein intake, energy intake and physical frailty : results from the Rotterdam Study

Josje D SchoufourOscar H FrancoJessica C Kiefte-de JongKaterina TrajanoskaBruno StrickerGuy BrusselleFernando RivadeneiraLies LahousseTrudy Voortman

A1 Journal Article in BRITISH JOURNAL OF NUTRITION

When the heart steals your breath away

Lies LahousseLowie E. G. W. Vanfleteren

Editorial material

2018

A genome-wide linkage study for chronic obstructive pulmonary disease in a Dutch genetic isolate identifies novel rare candidate variants

Ivana NedeljkovicNatalie TerzikhanJudith M VonkDiana A van der PlaatLies LahousseCleo C van DiemenBrian D HobbsDandi QiaoMichael H ChoGuy Brusselle et al.

A1 Journal Article in FRONTIERS IN GENETICS

Airways diseases : asthma, COPD and chronic cough highlights from the European Respiratory Society Annual Congress 2018

Huda BadriLies LahousseOmar S UsmaniAntonio Spanevello

Editorial material

Amazing pleiotropic effects of azithromycin

Editorial material

Asthma and its comorbidities in middle-aged and older adults : the Rotterdam study

Emmely de RoosLies LahousseKatia VerhammeGert-Jan BraunstahlM Arfan IkramJohannes CCM in't VeenBruno HCh StrickerGuy Brusselle

A1 Journal Article in RESPIRATORY MEDICINE

COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression

Ivana NedeljkovicLies LahousseElena Carnero-MontoroAlen FaizJudith M VonkKim de JongDiana A van der PlaatCleo C van DiemenMaarten van den BergeMa'en Obeidat et al.

A1 Journal Article in HUMAN MOLECULAR GENETICS

COPD is associated with an increased risk of peripheral artery disease and mortality

Natalie TerzikhanLies LahousseKatia VerhammeOscar H FrancoArfan M IkramBruno H StrickerGuy Brusselle

A2 Journal Article in ERJ OPEN RESEARCH

Genetic and non-genetic determinants and clinical consequences of impaired lung function

Natalie TerzikhanGuy BrusselleBH StrickerLies LahousseKatia Verhamme

Heritability and genome-wide association study of diffusing capacity of the lung

Natalie TerzikhanFangui SunFien VerhammeHieab HH AdamsDaan LothKen BrackeBruno HC StrickerLies LahousseJosée DupuisGuy Brusselle et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

LABA/LAMA fixed dose combination in chronic obstructive pulmonary disease : the impact on health-related quality of life

Marina LaborFulvio BraidoAndras BikovLies LahoussePaola RoglianiIlaria Baiardini

A1 Journal Article in RESPIRATION

Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function

Jiayi XuTraci M BartzGeetha ChittoorGudny EiriksdottirAni W ManichaikulFangui SunNatalie TerzikhanXia ZhouSarah L BoothGuy Brusselle et al.

A1 Journal Article in BRITISH JOURNAL OF NUTRITION

Meta-analysis of exome array data identifies six novel genetic loci for lung function

VE JacksonJC LatourelleLV WainAV SmithML GroveTM BartzM ObeidatMA ProvinceW GaoB Qaiser et al.

A2 Journal Article in WELLCOME OPEN RESEARCH

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Florence DemenaisPatricia Margaritte-JeanninKathleen C BarnesWilliam OC CooksonJanine AltmuellerWei AngR Graham BarrTerri H BeatyAllan B BeckerJohn Beilby et al.

A1 Journal Article in NATURE GENETICS

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

Annah B WyssTamar SoferMi Kyeong LeeNatalie TerzikhanJennifer N NguyenLies LahousseJeanne C LatourelleAlbert Vernon SmithTraci M BartzMary F Feitosa et al.

A1 Journal Article in NATURE COMMUNICATIONS

Physical activity and cause-specific mortality : the Rotterdam Study

Chantal M KoolhaasKlodian DhanaJosje D SchoufourLies LahousseFrank JA van RooijM Arfan IkramGuy BrusselleHenning TiemeierOscar H Franco

A1 Journal Article in INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Sarcopenia and its clinical correlates in the general population : the Rotterdam study

Katerina TrajanoskaJosje D SchoufourSirwan KL DarweeshElizabeth BenzCarolina Medina-GomezLouise JM AlferinkLies LahousseGuy BrusselleBruno StrickerSarwa Darwish Murad et al.

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

Serum phosphate levels are related to all-cause, cardiovascular and COPD mortality in men

Natalia Campos-ObandoLies LahousseGuy BrusselleBruno H StrickerAlbert HofmanOscar H FrancoAndré G UitterlindenM Carola Zillikens

A1 Journal Article in EUROPEAN JOURNAL OF EPIDEMIOLOGY

Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics

Ivana NedeljkovicElena Carnero-MontoroLies LahousseDiana A van der PlaatKim de JongJudith M VonkCleo C van DiemenAlen FaizMaarten van den BergeMa'en Obeidat et al.

A1 Journal Article in EUROPEAN JOURNAL OF HUMAN GENETICS

2017

A genome-wide linkage study for COPD in a Dutch genetic isolate

Ivana NedeljkovicNatalie TerzikhanJudith M VonkDiana A van der PlaatLies LahousseCleo C van DiemenGuy BrusselleH Marike BoezenCornelia M van DuijnNajaf Amin

Adherence to the 2015 Dutch dietary guidelines and risk of non-communicable diseases and mortality in the Rotterdam study

Trudy VoortmanJessica C Kiefte-de JongM Arfan IkramBruno H StrickerFrank JA van RooijLies LahousseHenning TiemeierGuy BrusselleOscar H FrancoJosje D Schoufour

A1 Journal Article in EUROPEAN JOURNAL OF EPIDEMIOLOGY

Association between lutein intake and lung function in adults : the Rotterdam Study

Debora Melo van LentElisabeth TM LeermakersAlbert HofmanBruno H StrickerGuy BrusselleOscar H FrancoLies LahousseJessica C Kiefte-de Jong

A1 Journal Article in BRITISH JOURNAL OF NUTRITION

Development of a healthy aging score in the population-based Rotterdam study : evaluating age and sex differences

Loes JaspersJosje D SchoufourNicole S ErlerSirwan KL DarweeshMarileen LP PortegiesSanaz SedaghatLies LahousseGuy BrusselleBruno H StrickerHenning Tiemeier et al.

A1 Journal Article in JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION

Dietary mineral intake and lung cancer risk : the Rotterdam study

Taulant MukaBledar KrajaRikje RuiterLies LahousseCatherine E De KeyserAlbert HofmanOscar H FrancoGuy BrusselleBruno H StrickerJessica C Kiefte-de Jong

A1 Journal Article in EUROPEAN JOURNAL OF NUTRITION

Epidemiology and impact of chronic bronchitis in chronic obstructive pulmonary disease

Lies LahousseLeen SeysGuy JoosOscar H FrancoBruno H StrickerGuy Brusselle

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Genes and pathways underlying susceptibility to impaired lung function in the context of environmental tobacco smoke exposure

K de JongJM VonkM ImbodenLies LahousseA HofmanGuy BrusselleNM Probst-HenschDS PostmaHM Boezen

A1 Journal Article in RESPIRATORY RESEARCH

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

Brian D HobbsKim de JongMaxime LamontagneYohan BosseNick ShrineMaria Soler ArtigasLouise V WainIan P HallVictoria E JacksonAnnah B Wyss et al.

A1 Journal Article in NATURE GENETICS

Genome-wide association study on the FEV1/FVC ratio in never-smokers identifies HHIP and FAM13A

Diana A van der PlaatKim de JongLies LahousseAlen FaizJudith M VonkCleo C. van DiemenIvana NedeljkovicNajaf AminGuy BrusselleAlbert Hofman et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Increased risk of peripheral arterial disease in individuals with COPD

Natalie TerzikhanLies LahousseKatia VerhammeOscar FrancoGuy BrusselleBruno Stricker

MicroRNA profiling reveals a role for microRNA-218-5p in the pathogenesis of chronic obstructive pulmonary disease

Griet ConickxPieter MestdaghFrancisco Avila CobosFien VerhammeTania MaesBart M VanaudenaerdeLeen SeysLies LahousseRichard Y KimAlan C Hsu et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Prevalence of hypertension among elderly asthmatics : the Rotterdam Study

Emmely De RoosLies LahousseArfan IkramBruno StrickerGuy BrusselleKatia Verhamme

Pulmonary artery to aorta ratio and risk of all-cause mortality in the general population : the Rotterdam Study

Natalie TerzikhanDaniel BosLies LahousseLennard WolffKatia MC VerhammeMaarten JG LeeningJanine F FelixHenning GallHossein A GhofraniOscar H Franco et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Pulmonary function and diffusion capacity are associated with pulmonary arterial systolic pressure in the general population : the Rotterdam study

Daan W LothLies LahousseMaarten JG LeeningBouwe P KrijtheJanine F FelixHenning GallAlbert HofmanH Ardeschir GhofraniOscar H FrancoBruno H Stricker et al.

A1 Journal Article in RESPIRATORY MEDICINE

Sex-differences in mortality within the COPD chronic bronchitis phenotype

Lies LahousseLeen SeysGuy JoosOscar FrancoBruno StrickerGuy Brusselle

Sex-specific genetic risk factors for chronic obstructive pulmonary disease

Guy BrusselleLies Lahousse

Editorial material

2016

Application of a healthy ageing phenotype in the population-based Rotterdam study : a gender-based perspective

Loes JaspersJosje SchoufourNicole ErlerSirwan DarweeshMarileen PortegiesSanaz SedaghatLies LahousseBruno StrickerHenning TiemeierArfan Ikram et al.

Asthma inflammatory phenotypes show differential microRNA expression in sputum

Tania MaesFrancisco Avila CobosFlorence SchleichValentina SorbelloMonique HenketKatleen De PreterKen BrackeGriet ConickxClaire MesnilJo Vandesompele et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cardiac effects of current treatments of chronic obstructive pulmonary disease

Lies LahousseKatia VerhammeBruno H StrickerGuy Brusselle

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Cardiac impact of inhaled therapy in the largest randomised placebo-controlled trial in COPD history : have we reached the SUMMIT?

Stefan AndreasChrister JansonMaarten van den BergeLies Lahousse

A2 Journal Article in ERJ OPEN RESEARCH

Chronic obstructive pulmonary disease and sudden cardiac death: a systematic review

Marten E van den BergBruno H StrickerGuy BrusselleLies Lahousse

A1 Journal Article in TRENDS IN CARDIOVASCULAR MEDICINE

Chronic obstructive pulmonary disease and the risk of stroke: the Rotterdam study

Marileen L PortegiesLies LahousseGuy JoosAlbert HofmanPeter J KoustaalBruno H StrickerGuy BrusselleM Arfan Ikram

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comorbiditeiten bij COPD

A4 Journal Article in BLOEDVATEN HART LONGEN

Epidemiology of chronic bronchitis in chronic obstructive pulmonary disease (COPD)

Leen SeysLies LahousseGuy JoosA HofmanB StrickerGuy Brusselle

GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium

Amy M MatteiniToshiko TanakaDavid KarasikGil AtzmonWen-Chi ChouJohn D EicherAndrew D JohnsonAlice M ArnoldMichele L CallisayaGail Davies et al.

A1 Journal Article in AGING CELL

Meta-analysis of the association of serum vitamin D with pulmonary function

J XuTM BartzG ChittoorG EiriksdottirAC Frazier-WoodLies LahousseJ LatourelleAW ManichaikulF SunNatalie Terzikhan et al.

Microrna-218-5p is implicated in the pathogenesis of chronic obstructive pulmonary disease

Griet ConickxPieter MestdaghFrancisco Avila CobosFien VerhammeTania MaesBM VanaudenaerdeLies LahousseGuy JoosJo VandesompeleKen Bracke et al.

Prevalence and incidence of COPD in smokers and non-smokers: the Rotterdam study

Natalie TerzikhanKatia MC VerhammeAlbert HofmanBruno H StrickerGuy BrusselleLies Lahousse

A1 Journal Article in EUROPEAN JOURNAL OF EPIDEMIOLOGY

Risk of frailty in elderly with COPD : a population-based study

Lies LahousseGijsbertus ZiereVincentius JA VerlindenM Carola ZillikensAndré G UitterlindenFernando RivadeneiraHenning TiemeierGuy JoosAlbert HofmanM Arfan Ikram et al.

A1 Journal Article in JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Rol van microRNA in neutrofiel astma

Tania MaesFrancisco Avila CobosFlorence SchleichValentina SorbelloMonique HenketKatleen De PreterKen BrackeGriet ConickxClaire MesnilJo Vandesompele et al.

A4 Journal Article in BLOEDVATEN HART LONGEN

Serum phosphate is related to all-cause, cardiovascular and COPD mortality in men: the Rotterdam study

MC ZillikensN Campos-ObandoLies LahousseGuy BrusselleBH StrickerOH FrancoAG Uitterlinden

Targeted therapy for older patients with uncontrolled severe asthma: current and future prospects

Emmely de RoosJCCM in 't VeenG-J BraunstahlLies LahousseGuy Brusselle

A1 Journal Article in DRUGS & AGING

The well-known gene HHIP and novel gene MECR are implicated in small airway obstruction

Diana A van der PlaatKim de JongLies LahousseAlen FaizJudith M VonkCleo C van DiemenIvana NedeljkovicNajaf AminMa'en ObeidatCornelia M van Duijn et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Understanding age-related diseases : report of the 2015 Ageing Summit

Lies LahousseEmmanuel MoyseSlavica KranticGuy Brusselle

Editorial material

2015

Chronic obstructive pulmonary disease and cerebrovascular disease: a comprehensive review

Lies LahousseHenning TiemeierM Arfan IkramGuy Brusselle

A1 Journal Article in RESPIRATORY MEDICINE

Chronic obstructive pulmonary disease and sudden cardiac death: the Rotterdam study

Lies LahousseMaartje N NiemeijerMarten E van den BergPeter R RijnbeekGuy JoosAlbert HofmanOscar H FrancoJaap W DeckersMark EijgelsheimBruno H Stricker et al.

A1 Journal Article in EUROPEAN HEART JOURNAL

Current research in aging : a report from the 2015 Ageing Summit

Emmanuel MoyseLies LahousseSlavica Krantic

A2 Journal Article in NEURODEGENERATIVE DISEASE MANAGEMENT

Gait patterns in COPD : the Rotterdam Study

Lies LahousseVincentius JA VerlindenJos N van der GeestGuy JoosAlbert HofmanBruno HC StrickerGuy BrusselleM Arfan Ikram

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Identification of differentially expressed microRNAs in neutrophilic asthma

Tania MaesKatleen De PreterFN SchleichM HenketKen BrackeLies LahoussePieter MestdaghGuy JoosGuy BrusselleR Louis

Integrative pathway genomics of lung function and airflow obstruction

Sina A GharibDaan W LothMaría Soler ArtigasTimothy P BirklandJemma B WilkLouise V WainJennifer A BrodyMa'en ObeidatDana B HancockWenbo Tang et al.

A1 Journal Article in HUMAN MOLECULAR GENETICS

Macro- en micro-angiopathie bij COPD

A4 Journal Article in BLOEDVATEN HART LONGEN

Prevalence of pulmonary hypertension in the general population : the Rotterdam study

Eduardo M MoreiraHenning GallMaarten JG LeeningLies LahousseDaan W LothBouwe P KrijtheJessica C Kiefte-de JongGuy BrusselleAlbert HofmanBruno H Stricker et al.

A1 Journal Article in PLOS ONE

Targeted therapy with inhaled corticosteroids in COPD according to blood eosinophil counts

Guy BrusselleKen BrackeLies Lahousse

Editorial material

The Rotterdam study : why fall in COPD?

Lies LahousseVincentius JA VerlindenM Arfan IkramGuy Brusselle

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

2014

Adverse outcomes of frailty in the elderly: the Rotterdam study

Lies LahousseBastiaan MaesGijsbertus ZiereDaan W LothVincentius JA VerlindenM Carola ZillikensAndré G UitterlindenFernando RivadeneiraHenning TiemeierOscar H Franco et al.

A1 Journal Article in EUROPEAN JOURNAL OF EPIDEMIOLOGY

Bone mineral density and chronic lung disease mortality: the Rotterdam study

Natalia Campos-ObandoMartha C Castano-BetancourtLing OeiOscar H FrancoBruno HCh StrickerGuy BrusselleLies LahousseAlbert HofmanHenning TiemeierFernando Rivadeneira et al.

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cause-specific mortality in mild COPD : the Rotterdam study

Lies LahousseGuy JoosAlbert HofmanBruno StrickerGuy Brusselle

Common genes underlying asthma and COPD? : genome-wide analysis on the Dutch hypothesis

Joanna SmolonskaGerard H KoppelmanCisca WijmengaJudith M VonkPieter ZanenMarcel BruinenbergIvan CurjuricMedea ImbodenGian-Andri ThunLude Franke et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Epidemiology of comorbidities in chronic obstructive pulmonary disease

Lies LahousseGuy BrusselleBH Stricker

Genome-wide association analysis identifies six new loci associated with forced vital capacity

Daan W LothMaria Soler ArtigasSina A GharibLouise V WainNora FranceschiniBeate KochTess D PottingerAlbert Vernon SmithQing DuanChris Oldmeadow et al.

A1 Journal Article in NATURE GENETICS

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function

Wenbo TangMatthew KowgierDaan W LothMaría Soler ArtigasBonnie R JoubertEmily HodgeSina A GharibAlbert V SmithIngo RuczinskiVilmundur Gudnason et al.

A1 Journal Article in PLOS ONE

Susceptibility to chronic mucus hypersecretion, a genome wide association study

Akkelies E DijkstraJoanna SmolonskaMaarten van den BergeCiska WijmengaPieter ZanenMarjan A LuingeMathieu PlatteelJan-Willem LammersMagnus DahlbackKerrie Tosh et al.

A1 Journal Article in PLOS ONE

β-adrenoceptor blockers and pulmonary function in the general population: the Rotterdam Study

Daan W LothGuy BrusselleLies LahousseAlbert HofmanHubert GM LeufkensBruno H Stricker

A1 Journal Article in BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

2013

Chronic obstructive pulmonary disease (COPD) exacerbations and carotid artery plaques : the Rotterdam study

Lies LahousseQuirijn JA van den BouwhuijsenDaan W LothGuy JoosAlbert HofmanJacqueline CM WittemanAad van der LugtGuy BrusselleBruno C Stricker

Chronic obstructive pulmonary disease and cerebral microbleeds: the Rotterdam study

Lies LahousseMeike W VernooijSirwan KL DarweeshSaloua AkoudadDaan W LothGuy JoosAlbert HofmanBruno H StrickerM Arfan IkramGuy Brusselle

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Chronic obstructive pulmonary disease and lipid core carotid artery plaques in the elderly: the Rotterdam Study

Lies LahousseQuirijn JA van den BouwhuijsenDaan W LothGuy JoosAlbert HofmanJacqueline CM WittemanAad van der LugtGuy BrusselleBruno H Stricker

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Frailty affects quality of spirometry : the Rotterdam study

Lies LahousseDW LothVJA VerlindenG ZiereM ZillikensAG UitterlindenF RivadeneiraH TiemeierM IkramA Hofman et al.

Impact of frailty on interpretability of spirometry : the Rotterdam study

Lies LahousseBastiaan MaesDW LothVJA VerlindenG ZiereMC ZillikensA UitterlindenF RivadeneiraH TiemeierMA Ikram et al.

Normal spirometry values in healthy elderly: the Rotterdam Study

Daan Willem LothTill IttermannLies LahousseAlbert HofmanHubert Gerardus Maria LeufkensGuy BrusselleBruno Hugo Stricker

A1 Journal Article in EUROPEAN JOURNAL OF EPIDEMIOLOGY

Pulmonary function is associated with pulmonary artery systolic pressure in the general population : the Rotterdam study

Daan LothLies LahousseMaarten LeeningBouwe KrijtheJanine FelixHenning TiedeArdeschir GhofraniOscar FrancoBruno StrickerGuy Brusselle

Statins, systemic inflammation and risk of death in COPD: the Rotterdam Study

Lies LahousseDaan W LothGuy JoosAlbert HofmanHubert GM LeufkensGuy BrusselleBruno H Stricker

A1 Journal Article in PULMONARY PHARMACOLOGY & THERAPEUTICS

2012

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

Jemma B WilkNick RG ShrineLaura R LoehrJing Hua ZhaoAni ManichaikulLorna M LopezAlbert Vernon SmithSusan R HeckbertJoanna SmolonskaWenbo Tang et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

2011

Interleukin 6 (IL6) plasma levels, common variation In the IL6 gene and the risk of chronic obstructive pulmonary disease : a prospective population-based cohort study

Lies LahousseYANNICK VAN DURMEKMC VerhammeL StolkM EijgelsheimD LothAG UitterlindenM BretelerGuy JoosA Hofman et al.

Mendelian randomization study of interleukin-6 in chronic obstructive pulmonary disease

YANNICK VAN DURMELies LahousseKatia MC VerhammeLisette StolkMark EijgelsheimDaan W LothAndre G UitterlindenMonique MB BretelerGuy JoosAlbert Hofman et al.

A1 Journal Article in RESPIRATION