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Researcher
Lien Verboom
Profile
Projects
Publications
Activities
Awards & Distinctions
6
Results
2023
Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion
Maria Giulia Doglio
Lien Verboom
Emily Ruilova Sosoranga
Ulrika Frising
Tomoko Asaoka
Yannick Gansemans
Filip Van Nieuwerburgh
Geert van Loo
Andy Wullaert
A1
Journal Article
in
SCIENCE IMMUNOLOGY
2023
OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection
Lien Verboom
Christopher Anderson
Maude Jans
Ioanna Petta
Gillian Blancke
Arne Martens
Mozes Sze
Tino Hochepied
Kodi Ravichandran
Lars Vereecke
et al.
A1
Journal Article
in
CELL DEATH & DISEASE
2023
Unravelling the role of OTULIN in liver and intestinal pathology
Lien Verboom
Geert van Loo
Dissertation
2023
2021
OTULIN in NF-κB signaling, cell death, and disease
Lien Verboom
Esther Hoste
Geert van Loo
A1
Journal Article
in
TRENDS IN IMMUNOLOGY
2021
OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity
Esther Hoste
Kim Lecomte
Karl Annusver
Niels Vandamme
Jana Roels
Sophia Maschalidi
Lien Verboom
Hanna-Kaisa Vikkula
Mozes Sze
Lisette Van Hove
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2021
2020
OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis
Lien Verboom
Arne Martens
Dario Priem
Esther Hoste
Mozes Sze
Hanna-Kaisa Vikkula
Lisette Van Hove
Sofie Voet
Jana Roels
Jonathan Maelfait
et al.
A1
Journal Article
in
CELL REPORTS
2020