Research Explorer

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Researcher

Lien Van den Bossche

Awards & Distinctions

9 Results

2018

Structural activation of pro-inflammatory human cytokine IL-23 by cognate IL-23 receptor enables recruitment of the shared receptor IL-12Rβ1

Yehudi BlochLaura BouchareychasRomain MerceronKatarzyna SkladanowskaLien Van den BosscheSammy DetrySrinath GovindarajanDirk ElewautFilomeen HaerynckMelissa Dullaers et al.

A1 Journal Article in IMMUNITY

2017

Bile acids as novel therapeutic agents for inflammatory bowel disease

Lien Van den BosscheDebby LaukensMartine De Vos

Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis

Sophie Van WeldenMartine De VosBen WielockxSimon TavernierMelissa DullaersSara NeytBenedicte DescampsLindsey DevisscherSarah DevrieseLien Van den Bossche et al.

A1 Journal Article in JOURNAL OF PATHOLOGY

Reduced mucosa-associated Butyricicoccus activity in patients with ulcerative colitis correlates with aberrant claudin-1 expression

Sarah DevrieseVenessa EeckhautAnnelies GeirnaertLien Van den BosschePieter HindryckxTom Van de WieleFilip Van ImmerseelRichard DucatelleMartine De VosDebby Laukens

A1 Journal Article in JOURNAL OF CROHNS & COLITIS

T84 monolayers are superior to Caco-2 as a model system of colonocytes

Sarah DevrieseLien Van den BosscheSophie Van WeldenTom HolvoetIris PinheiroPieter HindryckxMartine De VosDebby Laukens

A1 Journal Article in HISTOCHEMISTRY AND CELL BIOLOGY

Tauroursodeoxycholic acid protects bile acid homeostasis under inflammatory conditions and dampens Crohn’s disease-like ileitis

Lien Van den BosscheDaniel BorsboomSarah DevrieseSophie Van WeldenTom HolvoetLindsey DevisscherPieter HindryckxMartine De VosDebby Laukens

A1 Journal Article in LABORATORY INVESTIGATION

Treatment of intestinal fibrosis in experimental inflammatory bowel disease by the pleiotropic actions of a local Rho kinase inhibitor

Tom HolvoetSarah DevrieseKarolien CastermansSandro BolandDirk LeysenYves-Paul VandewynckelLindsey DevisscherLien Van den BosscheSophie Van WeldenMelissa Dullaers et al.

A1 Journal Article in GASTROENTEROLOGY

Ursodeoxycholic acid and its taurine/glycine conjugated species reduce colitogenic dysbiosis and equally suppress experimental colitis in mice

Lien Van den BosschePieter HindryckxLindsey DevisscherSarah DevrieseSophie Van WeldenTom HolvoetRamiro Vilchez VargasMarius VitalDietmar H PieperJulie Vandenbussche et al.

A1 Journal Article in APPLIED AND ENVIRONMENTAL MICROBIOLOGY

2014

Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death

Debby LaukensLindsey DevisscherLien Van den BosschePieter HindryckxRoosmarijn VandenbrouckeYves-Paul VandewynckelClaude CuvelierBrigitta BrinkmanClaude LibertPeter Vandenabeele et al.

A1 Journal Article in LABORATORY INVESTIGATION