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Researcher
Lien Lippens
Profile
Projects
Publications
Activities
Awards & Distinctions
27
Results
2024
Identification and validation of extracellular vesicle reference genes for the normalization of RT‐qPCR data
Cláudio Pinheiro
Niké Guilbert
Lien Lippens
Quentin Roux
Robin Boiy
Suzanne Fischer
Sofie Van Dorpe
Bram De Craene
Geert Berx
Tom Boterberg
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2024
2023
Extracellular vesicle analysis
An Hendrix
Lien Lippens
Cláudio Pinheiro
Clotilde Théry
Lorena Martin-Jaular
Jan Lötvall
Cecilia Lässer
Andrew F. Hill
Kenneth W. Witwer
A2
Journal Article
in
NATURE REVIEWS METHODS PRIMERS
2023
Integrating automated liquid handling in the separation workflow of extracellular vesicles enhances specificity and reproducibility
Sofie Van Dorpe
Lien Lippens
Robin Boiy
Cláudio Pinheiro
Glenn Vergauwen
Pekka Rappu
Ilkka Miinalainen
Philippe Tummers
Hannelore Denys
Olivier De Wever
et al.
A1
Journal Article
in
JOURNAL OF NANOBIOTECHNOLOGY
2023
Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma : results of the phase II PRIMMO study
Emiel De Jaeghere
Sandra Tuyaerts
An M. T. Van Nuffel
Ann Belmans
Kris Bogaerts
Regina Baiden-Amissah
Lien Lippens
Peter Vuylsteke
Stéphanie Henry
Xuan Bich Trinh
et al.
A1
Journal Article
in
CANCER IMMUNOLOGY IMMUNOTHERAPY
2023
2022
Association of cell death markers with tumor immune cell infiltrates after chemo-radiation in cervical cancer
Teodora-Eugenia Oltean
Lien Lippens
Kelly Lemeire
Caroline De Tender
Marnik Vuylsteke
Hannelore Denys
Katrien Vandecasteele
Peter Vandenabeele
Sandy Adjemian Catani
A1
Journal Article
in
FRONTIERS IN ONCOLOGY
2022
Biomarkers in gynecological cancer : the potential of tumor infiltrating immune cells and circulating extracellular vesicles
Lien Lippens
Hannelore Denys
An Hendrix
Katrien Vandecasteele
Dissertation
2022
2021
Automated liquid handling for highly specific and reproducible density‐based separation of extracellular vesicles from human body fluids
Sofie Van Dorpe
Lien Lippens
Robin Boiy
Hannelore Denys
Olivier De Wever
An Hendrix
C3
Conference
2021
Pembrolizumab, SBRT, and immunomodulation for recurrent and/or refractory cervical or endometrial carcinoma
Emiel De Jaeghere
Sandra Tuyaerts
Ann M.T. Van Nuffel
Lien Lippens
An Hendrix
P. Vuylsteke
S. Henry
X.B. Trinh
P.A. Van Dam
S. Aspeslagh
et al.
C3
Conference
2021
Recombinant extracellular vesicles as biological reference material for method development, data normalization and assessment of (pre-)analytical variables
Edward Geeurickx
Lien Lippens
Pekka Rappu
Bruno De Geest
Olivier De Wever
An Hendrix
A1
Journal Article
in
NATURE PROTOCOLS
2021
2020
Immunologic impact of chemoradiation in cervical cancer and how immune cell infiltration could lead towards personalized treatment
Lien Lippens
Mieke Van Bockstal
Emiel De Jaeghere
Philippe Tummers
Amin Makar
Sofie De Geyter
Koen Van de Vijver
An Hendrix
Katrien Vandecasteele
Hannelore Denys
A1
Journal Article
in
International Journal of Cancer
2020
Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction
Joeri Tulkens
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Bert Dhondt
Lien Lippens
Marie-Angélique De Scheerder
Ilkka Miinalainen
Pekka Rappu
Bruno De Geest
et al.
A1
Journal Article
in
GUT
2020
Splenic 18F-FDG uptake on baseline PET/CT is associated with oncological outcomes and tumor immune state in uterine cervical cancer
Emiel De Jaeghere
Frederiek Laloo
Lien Lippens
Mieke Van Bockstal
Kathia De Man
Eline Naert
Jo Van Dorpe
Koen Van de Vijver
Philippe Tummers
Amin Makar
et al.
A1
Journal Article
in
GYNECOLOGIC ONCOLOGY
2020
Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine
Bert Dhondt
Edward Geeurickx
Joeri Tulkens
Jan Van Deun
Glenn Vergauwen
Lien Lippens
Ilkka Miinalainen
Pekka Rappu
Jyrki Heino
Piet Ost
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2020
2019
Exploration of the urinary proteome in the search for new biomarkers for prostate cancer : a promising role for extracellular vesicles
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Lien Lippens
Joeri Tulkens
lkka Miinalainen
Pekka Rappu
Jyrki Heino Oulu, Finland
Piet Ost
et al.
C3
Conference
2019
Immunologic impact of chemoradiation in cervical cancer and how immune cell infiltration could lead towards personalized treatment
Lien Lippens
Mieke Van Bockstal
Emiel De Jaeghere
Philippe Tummers
Amin Makar
Sofie De Geyter
Koen Van de Vijver
An Hendrix
Katrien Vandecasteele
Hannelore Denys
C3
Conference
2019
PRIMMO study protocol : a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer
Sandra Tuyaerts
An MT Van Nuffel
Eline Naert
Peter A Van Dam
Peter Vuylsteke
Alex De Caluwé
Sandrine Aspeslagh
Piet Dirix
Lien Lippens
Emiel De Jaeghere
et al.
A1
Journal Article
in
BMC CANCER
2019
Splenic metabolic activity as biomarker in cervical cancer
Emiel De Jaeghere
Frederiek Laloo
Lien Lippens
Kathia De Man
Mieke Van Bockstal
Koen Van de Vijver
Philippe Tummers
Amin Makar
Pieter De Visschere
Olivier De Wever
et al.
C3
Conference
2019
The generation and use of recombinant extracellular vesicles as biological reference material
Edward Geeurickx
Joeri Tulkens
Bert Dhondt
Jan Van Deun
Lien Lippens
Glenn Vergauwen
Elisa Heyrman
Delphine De Sutter
Kris Gevaert
Francis Impens
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
2018
Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research
Edward Geeurickx
Elisa Heyrman
Jan Van Deun
Lien Lippens
Joeri Tulkens
Bert Dhondt
Glenn Vergauwen
Kris Gevaert
Francis Impens
Ilkka Miinalainen
et al.
C3
Conference
2018
Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research
Edward Geeurickx
Elisa Heyrman
Jan Van Deun
Lien Lippens
Joeri Tulkens
Bert Dhondt
Glenn Vergauwen
Kris Gevaert
Francis Impens
Ilkka Miinalainen
et al.
C3
Conference
2018
Repeatable, high-purity isolation of urinary extracellular vesicles for uro-oncological biomarker studies
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Joeri Tulkens
Lien Lippens
Ilkka Miinalainen
Pekka Rappu
Jyrki Heino
Nicolaas Lumen
et al.
C3
Conference
2018
Reproduceerbare isolatie van hoog-zuivere urinaire extracellulaire vesikels voor uro-oncologische biomerkerstudies
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Joeri Tulkens
Lien Lippens
Sarah Buelens
Elise De Bleser
Filip Poelaert
Tom Claeys
et al.
C3
Conference
2018
Reproducible high-purity isolation of urinary extracellular vesicles for uro-oncological biomarker studies
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Joeri Tulkens
Lien Lippens
Sarah Buelens
Elise De Bleser
Ilkka Miinalainen
Pekka Rappu
et al.
C3
Conference
2018
Reproducible isolation of high-purity urinary extracellular vesicles for uro-oncological biomarker studies
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Joeri Tulkens
Lien Lippens
Sarah Buelens
Elise De Bleser
Filip Poelaert
Tom Claeys
et al.
C3
Conference
2018
The small GTPase Rab27B stimulates secretion of a subpopulation of ARRDC1-positive small extracellular vesicles (SEV)
Lien Lippens
Robin Boiy
Bert Dhondt
Bruno De Geest
Katrien Vandecasteele
Hannelore Denys
Olivier De Wever
An Hendrix
C3
Conference
2018
2017
EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research
Jan Van Deun
Pieter Mestdagh
Patrizia Agostinis
Özden Akay
Sushma Anand
Jasper Anckaert
Zoraida Andreu Martinez
Tine Baetens
Els Beghein
Laurence Bertier
et al.
A1
Journal Article
in
NATURE METHODS
2017
Extracellular vesicles to diagnose and treat cancer
Joeri Tulkens
Lien Lippens
Glenn Vergauwen
Sarah Jeurissen
Bert Dhondt
Hannelore Denys
An Hendrix
A2
Journal Article
in
BELGIAN JOURNAL OF MEDICAL ONCOLOGY
2017