Research Explorer

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Researcher

Lien Dossche

112 Results

2023

First line therapy simple and extended approach /– overview + discussion/ Conclusion Case studies on enuresis

Johan Vande WalleLien Dossche

2022

Acute severe oligohydramnios in a female fetus with bilateral UPJ obstruction : a case report

Lien DosscheEvelien SnauwaertAgnieszka Prytula-EbelsJo DehoorneAnn RaesNOORTJE VAN OOSTRUMCaroline JamaerErik Van LaeckeAnne-Françoise SpinoitJohan Vande Walle

An unusual genetic diagnosis in a child presenting with end-stage renal disease

Evelien SnauwaertJo DehoorneAmélie DendoovenLien DosscheAgnieszka Prytula-EbelsAnn RaesTim VandammeJohan Vande Walle

Chronic after acute tubulo-interstitial nephritis (TIN) in a paediatric inflammatory bowel disease patient

Marieke VerhaegheJohan Vande WalleAnn RaesEvelien SnauwaertLien DosscheAmélie DendoovenAgnieszka Prytula-Ebels

Circadian rhythm of urinary water and solute excretion in children with enuresis

Sevasti KaramariaVincent DelensLien DosscheAnn RaesEvelien SnauwaertJohan Vande Walle

Circadian rhythm of water and solute excretion in nocturnal enuresis

Sevasti KaramariaLien DosscheVincent DelensEva DegraeuweAnn RaesReiner MauelCAROLINE VANDE WALLEKarel EveraertJohan Vande Walle

A1 Journal Article in PEDIATRIC NEPHROLOGY

Congenital nephrotic syndrome : a case of an unusual favorable disease course

Eline HermansJohan Vande WalleAgnieszka Prytula-EbelsJo DehoorneEvelien SnauwaertLien DosscheAnn Raes

Johan Vande WalleElke GasthuysLien Dossche

Enuresis and CAKUT

Johan Vande WalleLien DosscheSevasti Karamaria

From a harmless IV catheter to limb necrosis : a thromboembolic complication in an infant with nephrotic syndrome

Eline HermansJohan Vande WalleAgnieszka Prytula-EbelsJo DehoorneEvelyn DhontEvelien SnauwaertLien DosscheAnn Raes

Impact of new versus old International Children's Continence Society standardization on the classification of treatment naïve enuresis children at screening : the value of voiding diaries and questionnaires

Sevasti KaramariaNadejda RanguelovPernille HansenVeerle De BoePieter VerleyenNathalie SegersJohan Vande WalleLien DosscheAn Bael

A1 Journal Article in FRONTIERS IN PEDIATRICS

Keynote lecture: enuresis : who does not follow the guidelines?

Johan Vande WalleCharlotte Van HerzeeleKarlien DhondtLien DosscheSevasti Karamaria

Nocturnal enuresis : an update

Johan Vande WalleLien DosscheSören RittigSevasti Karamaria

Nocturnal enuresis : non responders : how to optimize therapy in refractory cases

Johan Vande WalleLien DosscheElke Gasthuys

Non neurogenic bladder dysfunction

Johan Vande WallePiet HoebekeErik Van LaeckeLien DosscheCATHERINE RENSONSevasti Karamaria

Predicting antidiuretic response to desmopressin in nocturnal enuresis

Sevasti KaramariaLien DosscheAnn RaesEvelien SnauwaertJohan Vande Walle

The influence of salt sensitivity phenotype on sodium excretion and diuresis : a chrononutrition pilot study

Upeksha Sewwandi AlwisIrina VerbakelKim PauwaertJoris DelangheLien DosscheJohn Van CampSaskia RoggemanKarel Everaert

A1 Journal Article in INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

The majority of MNE as well as NMNE patients have a therapeutic window for desmopressin therapy

Sevasti KaramariaLien DosscheAnn RaesEvelien SnauwaertJohan Vande Walle

The majority of MNE as well as NMNE patients have a therapeutic window for desmopressin therapy

Sevasti KaramariaLien DosscheAnn RaesEvelien SnauwaertJohan Vande Walle

Therapeutic window for desmopressin in noctunal enuresis

Sevasti KaramariaLien DosscheAnn RaesEvelien SnauwaertJohan Vande Walle

Unexpected acute severe oligohydramnios in a case of congenital bilateral UPJ–obstruction

Lien DosscheEvelien SnauwaertAgnieszka Prytula-EbelsJo DehoorneAnn RaesLieselot PeremansNOORTJE VAN OOSTRUMCaroline JamaerErik Van LaeckeAnne-Françoise Spinoit et al.

2021

A kinetic-based protocol for acute hyperammonaemia in neonates using CarpeDiem and Fresenius 4008 machine

Evelien SnauwaertJONATHAN DE RUDDERPATRICK VERLOOAnn RaesJohan Vande WalleAgnieszka Prytula-EbelsLien DosscheJo DehoorneSunny Eloot

Characteristics of nycthemeral rhythm of urinary water and solute excretion in children with enuresis referred to a tertiary center

Sevasti KaramariaVincent DelensLien DosscheAnn RaesJohan Vande Walle

Characteristics of nycthemeral rhythm of urinary water and solute excretion in children with enuresis

Sevasti KaramariaVincent DelensLien DosscheAnn RaesJohan Vande Walle

Circadian rhythm of urinary water and sodium excretion in children with MNE and NMNE enuresis

Sevasti KaramariaVincent DelensLien DosscheAnn RaesJohan Vande Walle

Circadian rhythm of urinary water and sodium excretion in children with MNE and NMNE enuresis

Sevasti KaramariaVincent DelensLien DosscheAnn RaesJohan Vande Walle

Circadian rhythm of water diuresis and salt excretion in treatment naïve children with nocturnal polyuria and the influence on desmopressin response

Sevasti KaramariaLien DosscheAnn RaesREINER MAUELErik Van LaeckeCharlotte Van HerzeeleJohan Vande Walle

Clinical characteristics of Galloway-Mowat syndrome and mutations in the TPRKB gene

Lieselot PeremansBert CallewaertAnn RaesJohan Vande WalleJo DehoorneLien DosscheEvelien Snauwaertagnieszka Prytula

Desmopressin oral lyophilisate in young children : new insights in pharmacokinetics and pharmacodynamics

Lien DosscheRobin MicheletPauline De BruyneCharlotte Van HerzeeleElke GasthuysSøren RittigAn VermeulenJohan Vande Walle

A1 Journal Article in ARCHIVES OF DISEASE IN CHILDHOOD

Desmopressin resistant monosymptomatic nocturnal enuresis : new pathophysiological and pharmacological insights

A2 Journal Article in BELGIAN JOURNAL OF PAEDIATRICS

Focus op underactive bladder : een kindgerichte aanpak

Ann RaesErik Van LaeckeAnne-Françoise SpinoitBieke SamijnCATHERINE RENSONIngeborg DhondtLien DosscheJohan Vande Walle

Initial screening for bedwetting : the use of questionnaires and voiding diaries : first results from a National Belgian study

Sevasti KaramariaN RanguelovPernille HansenVeerle De BoePieter VerleyenJohan Vande WalleLien DosscheAn Bael

Initial screening for bedwetting : the use of questionnaires and voiding diaries : first results from a National Belgian study

Sevasti KaramariaNadejda RanguelovPernille HansenVierle De BoeP VerleyenJohan Vande WalleLien DosscheAn Bael

Kinetic modeling as guide for dialysis prescription in acute neonatal hyperammonaemia : an example using CarpeDiem and Fresenius 4008 machine

JONATHAN DE RUDDERPatrick VerlooAgnieszka Prytula-EbelsLien DosscheJo DehoorneJohan Vande WalleEvelyn DhontAnn RaesWim Van BiesenSunny Eloot

Mysterious diagnosis in a child with failure to thrive

Annelies MatthysLisa GheuensSevasti KaramariaAgnieszka Prytula-EbelsEvelien SnauwaertLien DosscheJohan Vande WalleJO DEHOORNEAnn Raes

Paediatrician in Training Discussion Panel 1 : the challenges of tele-paediatrics : a lockdown-inspired clinical grand round

Eline HermansBram MeertensDelfien BogaertLien DosscheLevi Hoste

The value of questionnaire and diary in 2020 following the new ICCS standardization papers in treatment naïve patients

Sevasti KaramariaNadejda RanguelovPernille HansenVierle De BoePieter VerleyenJohan Vande WalleLien DosscheAnn Bael

Towards an algorithm-based tailored treatment of acute neonatal hyperammonaemia : an example using CarpeDiem and Fresenius 4008 machine

Evelien SnauwaertJONATHAN DE RUDDERPATRICK VERLOOAgnieszka Prytula-EbelsLien DosscheJo DehoorneJohan Vande WalleEvelyn DhontAnn RaesWim Van Biesen et al.

l' Enurésie : comment gérer : L’arbre décisionnel

Johan Vande WalleLien DosscheAnn RaesAnne-Françoise Spinoit

2020

An integrated paediatric population PK/PD analysis of dDAVP : how do PK differences translate to clinical outcomes?

Robin MicheletLien DosscheCharlotte Van HerzeelePauline De BruyneElke GasthuysJan Van BocxlaerJohan Vande WalleAn Vermeulen

A1 Journal Article in CLINICAL PHARMACOKINETICS

Chronotherapie en bioritmes

Johan Vande WalleEvelien SnauwaertLien Dossche

Could evening dietary protein intake play a role in nocturnal polyuria?

Upeksha Sewwandi AlwisJoris DelangheLien DosscheJohan Vande WalleJohn Van CampThomas F. MonaghanSaskia RoggemanKarel Everaert

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Desmopressin resistant monosymptomatic nocturnal enuresis : new pathophysiological and pharmacological insights

Lien DosscheJohan Vande WalleSören RittigElke Gasthuys

Electrolytes in pediatrics : part 2

Johan Vande WalleLien Dossche

Enuresis : evaluation and treatment

Johan Vande WalleLien DosscheElke Gasthuys

Etiology and clinical features of enuresis

Johan Vande WalleLien DosscheSevasti Karamaria

Het goed gebruik van 24 h ABPM / chronotherapie : circadian rythms

Johan Vande WalleEvelien SnauwaertLien Dossche

Pediatric pharmacology of desmopressin in children with enuresis : a comprehensive review

Elke GasthuysLien DosscheRobin MicheletJens Peter NorgaardMathias DevreeseSiska CroubelsAn VermeulenJan Van BocxlaerJohan Vande Walle

A1 Journal Article in PEDIATRIC DRUGS

SafePedrug / BPCRN + Belgium pediatric clinical research network : the next step in pediatric drug research

Johan Vande WalleSevasti KaramariaLien DosscheLieve NuytinckLeen De Taeye

Some trainees are more equal than others : the paediatric residency payment gap, as illustrated in a cross-sectional study in Flanders

Levi HosteSiel DaelemansLien DosscheAnn De GuchtenaereAn Bael

A2 Journal Article in BELGIAN JOURNAL OF PAEDIATRICS

The long-term added value of voiding school for children with refractory non-neurogenic overactive bladder : an inpatient bladder rehabilitation program

Lien DosscheEvelien SnauwaertCATHERINE RENSONJOHAN VAN DAELEAnn RaesJo DehoorneSanne RoelsErik Van LaeckeCharlotte Van HerzeelePiet Hoebeke et al.

A1 Journal Article in JOURNAL OF PEDIATRIC UROLOGY

2019

SAFEPEDRUG : safer pediatric drugs for children: what have we learned?

Elke GasthuysJohan Vande WalleLien DosscheLieve NuytinckRobin MicheletAn VermeulenSevasti Karamaria

Transition to the adult care children with bladder and bowel problems

Johan Vande WalleLien DosscheKarel Everaert

2018

Claiming desmopressin therapeutic equivalence in children requires pediatric data : a population PKPD analysis

Robin MicheletLien DosscheCharlotte Van HerzeeleJan Van BocxlaerAn VermeulenJohan Vande Walle

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Decreased nocturnal sodium excretion in desmopressin responsive enuresis with nocturnal polyuria

Rik Van HooimissenLien DosscheREINER MAUELSevasti KaramariaCharlotte Van HerzeeleErik Van LaeckeAnn RaesJohan Vande Walle

Desmopressin what is new? : paediatric drug development : towards maturity

Elke GasthuysRobin MicheletLien DosscheJohan Vande Walle

Does one size of desmopressin oral lyophilisate formulation really fits them all? : exploring the need to perform pharmacokinetic- and pharmacodynamic trials in children

Lien DosscheRobin MicheletAnn RaesPauline De BruyneJohan Vande Walle

Ethical considerations of researchers conducting pediatric clinical drug trials : a qualitative survey in two Belgian university children's hospitals

Wannes Van HoofKevin MeestersLien DosscheDaphné ChristiaensPauline De BruyneJohan Vande Walle

A1 Journal Article in EUROPEAN JOURNAL OF PEDIATRICS

Evaluation of a standardized appraoch of desmopressin resistant polyuria in MNE

REINER MAUELVALERIE SCHAMPAnn RaesGREET PAUWELSAn-Sophie CornelisJoke YsenbaertMieke BouvryLien DosscheEvelien SnauwaertErik Van Laecke et al.

Evaluation of the subjective burden of alarm treatment in children with nocturnal enuresis

Leonie De GrootTessa Du FourAnn RaesCharlotte Van HerzeeleAnne-Françoise SpinoitSevasti KaramariaLien DosscheJohan Vande Walle

Is there a place for diet adjustment in standardurotherapy in enuresis

VALERIE VAN BOGAERTNATHALIE DE BRUIJNAnn RaesNathalie SegersLien DosscheAgnieszka Prytula-EbelsJohan Vande Walle

PK/PD studies in pigs leading to optimization of treatment dose in MNE?

Elke GasthuysLien DosscheSiska CroubelsPauline De BruyneMathias DevreeseAn VermeulenJohan Vande Walle

Paediatric departments need to improve residents' training in adolescent medicine and health : a position paper of the European Academy of Paediatrics

Pierre-Andre MichaudLenneke SchrierRobert Ross-RusselLaila van der HeijdenLien DosscheSian CopleyTommaso AlterioArtur MazurLukasz DembinskiAdamos Hadjipanayis et al.

A1 Journal Article in EUROPEAN JOURNAL OF PEDIATRICS

Pediatric drug development: towards maturity : desmopressin as a case

Elke GasthuysRobin MicheletLien DosschePauline De BruyneJohan Vande WalleAn VermeulenMathias DevreeseSiska Croubels

Socioeconomic factors in pathogenesis of enuresis

Britt WolfsCharlotte Van HerzeeleAnn RaesLien DosscheSevasti KaramariaTove Holm-LarsenJohan Vande Walle

Socioeconomic factors in pathogenesis of enuresis

Britt WolfsCharlotte Van HerzeeleAnn RaesLien DosscheSevasti KaramariaTove Holm-LarsenJohan Vande Walle

The choice between deceased- vs living-donor renal transplantation in children : analysis of data from a Belgian tertiary center

KATTY VAN CAUWENBERGHEAnn RaesLUTGARDE PAUWELSJo DehoorneLUC COLENBIECLEMENT DEQUIDTLien DosscheJohan Vande WalleAgnieszka Prytula-Ebels

A1 Journal Article in PEDIATRIC TRANSPLANTATION

The future paediatricians in Flanders

Anne RochtusLien DosscheThomas RensonKoen HuysentruytJulie WillekensAnn De GuchtenaerePhilippe Alliet

A2 Journal Article in BELGIAN JOURNAL OF PAEDIATRICS

Update on enuresis 2 : evaluation and management

Johan Vande WalleLien Dossche

Voiding school for children with refractory non-neurogenic overactive bladder : a 10-year retrospective study

Lien DosscheEvelien SnauwaertAnne-Françoise SpinoitCATHERINE RENSONJOHAN VAN DAELEAnn RaesJo DehoorneSanne RoelsPiet HoebekeErik Van Laecke et al.

2017

Een gemeenschappelijk centraal mechanisme voor bedplassen en psychologische problemen bij kinderen?

Charlotte Van HerzeeleLien DosscheKarlien DhondtJohan Vande Walle

A4 Journal Article in NEURONE (NEDERLANDSE ED.)

Factors influencing daytime and combined incontinence in children with cerebral palsy

Bieke SamijnLien DosscheChristine Van den BroeckJohan Vande WalleFrank PlasschaertErik Van Laecke

Factors influencing daytime or combined incontinence in children with cerebral palsy

Bieke SamijnLien DosscheChristine Van den BroeckJohan Vande WalleFrank PlasschaertErik Van Laecke

2016

Bioequivalence in adults does not mean bioequivalence in children

Lien DosscheRobin MicheletPauline De BruyneJan Van BocxlaerAn VermeulenJohan Vande Walle

Bioequivalence in adults is not always bioequivalence in children

Lien DosscheAnn RaesPauline De BruyneRobin MicheletAn VermeulenJan Van BocxlaerJohan Vande Walle

Bladder volume in screening battery for enuresis : how to evaluate?

Nathalie SegersC DebuschereW SophieD GuentherAnn RaesLien DosscheJohan Vande Walle

Bladder volume in screening battery of enuresis : how to evaluate?

Claire DebusschereSophie WoutersDelphine GuenterLien DosscheAnn RaesCharlotte Van HerzeeleJohan Vande Walle

Circadian rhythm of glomerular filtration and solute handling related to nocturnal enuresis

Lien DosscheAnn RaesPiet HoebekePauline De BruyneJohan Vande Walle

A1 Journal Article in JOURNAL OF UROLOGY

De urineproductie te hoog tijdens de nacht bij kinderen

Johan Vande WalleLien DosscheAnn Raes

Effect of food and pharmaceutical formulation on desmopressin pharmacokinetics in children

Robin MicheletLien DosschePauline De BruynePieter ColinKoen BousseryJohan Vande WalleJan Van BocxlaerAn Vermeulen

Effect of food and pharmaceutical formulation on desmopressin pharmacokinetics in children

Robin MicheletLien DosschePauline De BruynePieter ColinKoen BousseryJohan Vande WalleJan Van BocxlaerAn Vermeulen

Effects of food and pharmaceutical formulation on desmopressin pharmacokinetics in children

Robin MicheletLien DosschePauline De BruynePieter ColinKoen BousseryJohan Vande WalleJan Van BocxlaerAn Vermeulen

A1 Journal Article in CLINICAL PHARMACOKINETICS

How do researchers weigh ethical priciples in pediatric clinical trials?

Wannes Van HoofPauline De BruyneLien DosscheKevin MeestersSofie BekaertJohan Vande Walle

Influence of fluid intake on functional bladder volume and nighttime diuresis in nocturnal enuresis

Mieke BouvryAnn RaesLien DosscheN DebruijnN SeegersC VanherzeeleAgnieszka Prytula-EbelsJohan Vande Walle

Limited role for diet advice as first line urotherapy in schildren with primary enuresis

VALERIE VAN BOGAERTAnn RaesLien DosscheNathalie SegersNATHALIE DE BRUIJNAn Sophie CornelisANN DESLOOVERECharlotte Van HerzeeleJohan Vande Walle

Plasklas : en hoe moet het nu thuis? Psycho-educatie voor het kind en de ouders

Catherine Renson

Predictive parameters for desmopressin response in enuresis : a two-center study

Lien DosscheK KamperisCharlotte Van HerzeeleJohan Vande WalleS Rittig

Predictive value of urinary osmolality in the early morning for desmopressin response

Lien DosscheAnn RaesMieke BouvryNathalie SegersReiner MauelCharlotte Van HerzeeleJohan Vande Walle

Predictive value of urinary osmolality in the early morning for desmopressin response

Lien DosscheAnn RaesReiner MauelPauline De BruyneAnn Sophie CornelisJohan Vande Walle

Recurrent hematuria due to nutcracker syndrome : imaging techniques

Lien DosscheMARTINE BESOUWAnn Raes

Recurrent hematuria due to nutcrackers syndrome: imaging techniques

Lien DosscheAnn RaesMARTINE BESOUW

Recurrent hematuria due to the nutcracker syndrome : imaging techniques

Lien DosscheAnn RaesMARTINE BESOUW

Recurrent vomiting in a 12-year old boy with diagnostic suspicion of hyperoxaluria : a case report

Lien DosscheAnn RaesJohan Vande WalleKatrien Van RenterghemSaskia Vande Velde

Reintroduction of alarm therapy in children with refractory MNE

Lien DosscheD DemeesterL DeryckeS CelenJ ImschooCATHERINE RENSONAnn RaesPiet HoebekeErik Van LaeckeCharlotte Van Herzeele et al.

Standardized (ICCS) screening tool in diagnostic approach of nocturnal enuresis results in higher incidence of NMNE to MNE

Sophie WoutersClaire DebusschereDelphine GuenterLien DosscheAnn RaesJohan Vande Walle

The pathophysiology of monosymptomatic nocturnal enuresis with special emphasis on the circadian rhythm of renal physiology

Lien DosscheJohan Vande WalleCharlotte Van Herzeele

A1 Journal Article in EUROPEAN JOURNAL OF PEDIATRICS

Therapy-resistant enuresis in adolescents, when sport activity in the evening

Lien DosscheAnn RaesNathalie SegersMieke BouvryNATHALIE DE BRUIJNAn Sophie CornelisCharlotte Van HerzeeleJohan Vande Walle

Therapy-resistant enuresis in adolescents, when sporting in the evening

Lien DosscheMieke BouvryAnn Sophie CornelisNATHALIE DE BRUIJNAnn RaesJohan Vande Walle

Validation of 24 h urinary concentration prophyle against diary to identify characteristics of nocturnal polyuria

Delphine GuenterAnn RaesLien DosscheNathalie SegersCharlotte Van HerzeeleJohan Vande Walle

Zin of onzin van urotherapie bij enuresis

VALERIE VAN BOGAERTLien DosscheNathalie SegersCATHERINE RENSONCharlotte Van HerzeeleJohan Vande Walle

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

arts consultatie in de praktijk : workshop namiddag

NATHALIE DE BRUIJNJohan Vande Walle

arts consultatie in de praktijk : workshop voormiddag

NATHALIE DE BRUIJNJohan Vande Walle

plaswekker (dag/nacht) : neuromodulatie : namiddag

Catherine RensonJohan Vande Walle

plaswekker (dag/nacht) : neuromodulatie : voormiddag

Catherine RensonJohan Vande Walle

2015

Mogelijke valkuilen bij de interpretatie van de waterstofademtest bij kinderen

Lieve BoelLien DosscheSaskia Vande VeldeRuth De BruyneMyriam Van WinckelStephanie Van Biervliet

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Predictive value of urinary osmolality in the early morning for desmopressin response in enuresis

Lien DosscheNathalie DebruynAnn Sophie CornelisAnn RaesJohan Vande Walle

Reintroduction of alarm therapy in children with refractory MNE

Lien DosscheDorien DemeesterLore DeryckeJulie ImschootStefanie CeelenAnn RaesCharlotte Van HerzeeleJohan Vande Walle

2014

Neonatal cholestasis and vitamin K deficient bleeding diathesis as a clue for cystic fibrosis

Lien DosscheMyriam Van WinckelSaskia Vande VeldeRuth De BruyneStephanie Van Biervliet

2013

Circadian rhythm of glomerular filtration (GFR) rhythm and sodium-excretion in children with enuresis

Lien DosscheAnn RaesJo DehoorneReiner MauelJohan Vande Walle

2012

Circadian rhythm of glomerular filtration (GFR) rhythm and sodium-excretion in children with enuresis nocturnal

Lien DosscheAnn RaesPiet HoebekeErik Van LaeckeREINER MAUELAnn De GuchtenaereJohan Vande Walle

2010

Hypercalciuria is related to osmolar excretion in children with nocturnal enuresis

Ann RaesLien DosscheNele HertegonneLaure NuytemansPiet HoebekeErik Van LaeckeRaymond AMG DonckerwolckeJohan Vande Walle

A1 Journal Article in JOURNAL OF UROLOGY

2009

Hypercalciuria in children with nocturnal enuresis nocturna is related to increased osmotic diuresis

Laure NuytemansLien DosscheR MauelAnn RaesJohan Vande Walle