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Researcher
Leen Seys
Profile
Projects
Publications
Activities
Awards & Distinctions
18
Results
2024
Role of glycosylation in the immunogenicity of the nematode specific activation-associated secreted proteins (ASPs) and its implication in vaccine efficacy
Laurens Zwanenburg
Peter Geldhof
Leen Seys
Dissertation
2024
2023
Plant-based production of a protective vaccine antigen against the bovine parasitic nematode Ostertagia ostertagi
Laurens Zwanenburg
Jimmy Borloo
Bregt Decorte
Myrna J. M. Bunte
Sanaz Mokhtari
Sonia Serna
Niels-C. Reichardt
Leen Seys
Angela van Diepen
Arjen Schots
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2023
2022
TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C
Levi Hoste
Lisa Roels
Leslie Naesens
Victor Bosteels
Stijn Vanhee
Sam Dupont
Cedric Bosteels
Robin Browaeys
Niels Vandamme
Kevin Verstaen
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2022
2021
ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation
Richard de Reuver
Evelien Dierick
Bartosz Wiernicki
Katrien Staes
Leen Seys
Ellen De Meester
Tuur Muyldermans
Alexander Botzki
Bart Lambrecht
Filip Van Nieuwerburgh
et al.
A1
Journal Article
in
CELL REPORTS
2021
Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID) : a factorial, randomised, controlled trial
Jozefien Declercq
Karel Van Damme
Elisabeth De Leeuw
Bastiaan Maes
Cedric Bosteels
Simon Tavernier
Stefanie De Buyser
Roos Colman
Maya Hites
Gil Verschelden
et al.
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2021
2018
Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD
Elise De Smet
Leen Seys
Fien Verhamme
Bart M Vanaudenaerde
Guy Brusselle
Colin D Bingle
Ken Bracke
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
2018
DPP4, the Middle East respiratory syndrome coronavirus receptor, is upregulated in lungs of smokers and chronic obstructive pulmonary disease patients
Leen Seys
W Widagdo
Fien Verhamme
Alex Kleinjan
Wim Janssens
Guy Joos
Ken Bracke
Bart L Haagmans
Guy Brusselle
A1
Journal Article
in
CLINICAL INFECTIOUS DISEASES
2018
2017
Dysregulation of type 2 innate lymphoid cells and TH2 cells impairs pollutant-induced allergic airway responses
Katrien De Grove
Sharen Provoost
Rudi W Hendriks
Andrew NJ McKenzie
Leen Seys
Smitha Kumar
Tania Maes
Guy Brusselle
Guy Joos
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2017
Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure
Fien Verhamme
Leen Seys
Elise De Smet
Sharen Provoost
W Janssens
Dirk Elewaut
Guy Joos
Guy Brusselle
Ken Bracke
A1
Journal Article
in
MUCOSAL IMMUNOLOGY
2017
Epidemiology and impact of chronic bronchitis in chronic obstructive pulmonary disease
Lies Lahousse
Leen Seys
Guy Joos
Oscar H Franco
Bruno H Stricker
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2017
MicroRNA profiling reveals a role for microRNA-218-5p in the pathogenesis of chronic obstructive pulmonary disease
Griet Conickx
Pieter Mestdagh
Francisco Avila Cobos
Fien Verhamme
Tania Maes
Bart M Vanaudenaerde
Leen Seys
Lies Lahousse
Richard Y Kim
Alan C Hsu
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2017
The role of dicer in alveolar macrophages and dendritic cells in smoke-induced inflammation
Elise De Smet
Pieter Mestdagh
S Provoost
Leen Seys
Guy Joos
Karim Vermaelen
Guy Brusselle
Ken Bracke
C3
Conference
2017
2016
B cells in chronic obstructive pulmonary disease : moving to center stage
Francesca Polverino
Leen Seys
Ken Bracke
Caroline A Owen
A1
Journal Article
in
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
2016
Epidemiology of chronic bronchitis in chronic obstructive pulmonary disease (COPD)
Leen Seys
Lies Lahousse
Guy Joos
A Hofman
B Stricker
Guy Brusselle
C3
Conference
2016
Mucosal immunity in COPD : from mucociliary dysfunction to lymphoid follicles
Leen Seys
Guy Brusselle
Ken Bracke
Dissertation
2016
2015
Airway surface dehydration aggravates cigarette smoke-induced hallmarks of COPD in mice
Leen Seys
Fien Verhamme
Lisa Dupont
Elke Desauter
Julia Duerr
Ayca Seyhan Agircan
Griet Conickx
Guy Joos
Guy Brusselle
Marcus A Mall
et al.
A1
Journal Article
in
PLOS ONE
2015
Role of B cell-activating factor in chronic obstructive pulmonary disease
Leen Seys
Fien Verhamme
Anja Schinwald
Hamida Hammad
Danen Mootoosamy Cunoosamy
Claudie Bantsimba-Malanda
Alan Sabirsh
Eileen McCall
Liz Flavell
Ronald Herbst
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2015
2013
Role of CXCL13 in cigarette smoke-induced lymphoid follicle formation and chronic obstructive pulmonary disease
Ken Bracke
Fien Verhamme
Leen Seys
Claudie Bantsimba-Malanda
Danen Mootoosamy Cunoosamy
Ronald Herbst
Hamida Hammad
Bart Lambrecht
Guy Joos
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2013