Research Explorer

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Researcher

Leen Paelinck

Publications & Research Data

Awards & Distinctions

58 Results

2025

Integrating genetic polymorphisms and clinical data to develop predictive models for skin toxicity in breast cancer radiation therapy

Ester Aguado-FlorVictoria M. ReyesVíctor NavarroMeritxell MollàMiguel E. Aguado-BarreraManuel AltabasDavid AzriaAdinda BatenCeline BourgierRenée Bultijnck et al.

A1 Journal Article in BREAST

2023

Dosimetric and hematologic implications of prostate-only versus whole pelvic radiotherapy : results of the multicentric phase 3 PROPER study

Valerie FonteyneWilleke DanckaertPiet OstCharlien BerghenKatrien VandecasteeleBen VannesteKato RansNick LiefhoogheSteven WallaertLeen Paelinck

A1 Journal Article in TECHNOLOGY IN CANCER RESEARCH & TREATMENT

2022

Accelerated radiotherapy in patients over sixty years old after mastectomy : acute and one-year physician-assessed toxicity and health-related quality of life

Vincent VakaetHans Van HulleViktor QuataertPieter DeseyneMax SchoepenLeen PaelinckGiselle PostAnnick Van GrevelingBruno SpeleersMarcus Mareel et al.

A2 Journal Article in BREAST DISEASE

Four irradiation and three positioning techniques for whole breast radiotherapy : is sophisticated always better?

Max SchoepenBruno SpeleersWilfried De NeveVincent VakaetPieter DeseyneLeen PaelinckAnnick Van GrevelingLiv VeldemanJan DetandWerner De Gersem

A1 Journal Article in JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS

International consensus guidelines for adjuvant radiation therapy for bladder cancer after radical cystectomy : update from an IBIS workgroup

Flor VerghotePaul SargosJohn P. ChristodouleasVedang MurthyBrian C. BaumannPiet DirixCharlien BerghenLeen PaelinckTom VercauterenValerie Fonteyne

A1 Journal Article in PRACTICAL RADIATION ONCOLOGY

Prone breast and lymph node irradiation in 5 or 15 fractions : a randomized 2 x 2 design comparing dosimetry, acute toxicity, and set-up errors

Vincent VakaetPieter DeseyneMax SchoepenMichael StouthandelGiselle PostBruno SpeleersAnnick Van GrevelingChristel MontenMarcus MareelHans Van Hulle et al.

A1 Journal Article in PRACTICAL RADIATION ONCOLOGY

Reproducibility of repeated breathhold and impact of breathhold failure in whole breast and regional nodal irradiation in prone crawl position

Pieter DeseyneBruno SpeleersLeen PaelinckWerner De GersemWilfried De NeveMax SchoepenAnnick Van GrevelingHans Van HulleVincent VakaetGiselle Post et al.

A1 Journal Article in SCIENTIFIC REPORTS

2021

5-year outcomes of a randomized trial comparing prone and supine whole breast irradiation in large-breasted women

Vincent VakaetHans Van HulleMarie VergotteMax SchoepenPieter DeseyneAnnick Van GrevelingGiselle PostBruno SpeleersLeen PaelinckChristel Monten et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Acute toxicity and health-related quality of life after accelerated whole breast irradiation in 5 fractions with simultaneous integrated boost

Hans Van HulleVincent VakaetChristel MontenPieter DeseyneMax SchoepenCato ColmanLeen PaelinckAnnick Van GrevelingGiselle PostBruno Speleers et al.

A1 Journal Article in BREAST

Effects of deep inspiration breath hold on prone photon or proton irradiation of breast and regional lymph nodes

Bruno SpeleersMax SchoepenFrancesca BelosiVincent VakaetWilfried De NevePieter DeseyneLeen PaelinckTom VercauterenMichael J. ParkesTony Lomax et al.

A1 Journal Article in SCIENTIFIC REPORTS

Radiotherapy for the vulvar region in frog-leg position : improving reproducibility and comfort.

Wendy De VosLUDWIG VAN DEN BERGHELeen PaelinckStefan VansteenkisteBrenda DepaepeSandra LauwersJulie MortierEmma De RijckeAxel Van DammeKatrien Vandecasteele

Two-year toxicity of simultaneous integrated boost in hypofractionated prone breast cancer irradiation : comparison with sequential boost in a randomized trial

Hans Van HulleEline DesaunoisVincent VakaetLeen PaelinckMax SchoepenGiselle PostANNICK VAN GREVELINGBruno SpeleersMarcus MareelWilfried De Neve et al.

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

2020

Crawl positioning improves set-up precision and patient comfort in prone whole breast irradiation

Pieter DeseyneBruno SpeleersWilfried De NeveBert BouteLeen PaelinckVincent VakaetHans Van HulleMax SchoepenMichael StouthandelAnnick Van Greveling et al.

A1 Journal Article in SCIENTIFIC REPORTS

Two-year toxicity of hypofractionated breast cancer radiotherapy in five fractions

Hans Van HulleVincent VakaetKathleen DeckmynChristel MontenLeen PaelinckANNICK VAN GREVELINGGiselle PostMax SchoepenArthur FonteyneBruno Speleers et al.

A1 Journal Article in ACTA ONCOLOGICA

2019

Accelerating adjuvant breast irradiation in women over 65 years : matched case analysis comparing a 5-fractions schedule with 15 fractions in early and locally advanced breast cancer

Hans Van HulleDieter NaudtsEllen DeschepperVincent VakaetLeen PaelinckGiselle PostANNICK VAN GREVELINGBruno SpeleersPieter DeseyneYolande Lievens et al.

A1 Journal Article in JOURNAL OF GERIATRIC ONCOLOGY

Comparison of supine or prone crawl photon or proton breast and regional lymph node radiation therapy including the internal mammary chain

Bruno SpeleersFrancesca M BelosiWerner De GersemPieter DeseyneLeen PaelinckAlessandra BolsiAntony J LomaxBert BouteANNICK VAN GREVELINGChristel Monten et al.

A1 Journal Article in SCIENTIFIC REPORTS

Longitudinal radiomics of cone-beam CT images from non-small cell lung cancer patients : evaluation of the added prognostic value for overall survival and locoregional recurrence

Janna E van TimmerenWouter van ElmptRalph TH LeijenaarBart ReymenRené MonshouwerJohan BussinkLeen PaelinckEvelien BogaertCarlos De WagterELHASEEN ELAMIN et al.

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

REQUITE: A prospective multicentre cohort study of patients undergoing radiotherapy for breast, lung or prostate cancer

Petra SeiboldAdam WebbMiguel E. Aguado-BarreraDavid AzriaCeline BourgierMuriel BrenguesErik BriersRenée BultijnckPatricia Calvo-CrespoAna Carballo et al.

A1 Journal Article in Radiotherapy and Oncology

2018

A new approach for modeling patient overall radiosensitivity and predicting multiple toxicity endpoints for breast cancer patients

Chamberlain MbahKim De RuyckSilke De SchrijverCharlotte De SutterKimberly SchiettecatteChristel MontenLeen PaelinckWilfried De NeveHubert ThierensCatharine West et al.

A1 Journal Article in ACTA ONCOLOGICA

2017

Adaptive radiotherapy for locally advanced non-small cell lung cancer : dosimetric gain and treatment outcome prediction

PATRICK BERKOVICLeen PaelinckAkos GulybanMarc Van EijkerenVeerle SurmontYolande LievensKatrien Vandecasteele

A1 Journal Article in ACTA ONCOLOGICA

Does an integrated boost increase acute toxicity in prone hypofractionated breast irradiation? : a randomized controlled trial

Leen PaelinckAkos GulybanFerenc LakosiTom VercauterenWerner De GersemBruno SpeleersChristel MontenTHOMAS MULLIEZPatrick BerkovicANNICK VAN GREVELING et al.

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Highly accelerated irradiation in 5 fractions (HAI-5) : feasibility in elderly women with early or locally advanced breast cancer

Christel MontenYolande LievensAna Maria Luiza OlteanuLeen PaelinckBruno SpeleersPieter DeseyneRudy Van den BroeckeWilfried De NeveLiv Veldeman

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Potential benefits of crawl position for prone radiation therapy in breast cancer

Bert BouteWilfried De NeveBruno SpeleersANNICK VAN GREVELINGChristel MontenTom Van HoofJoris Van de VeldeLeen PaelinckWerner De GersemTom Vercauteren et al.

A1 Journal Article in JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS

Tumor regression gradient predicts disease free survival

Patrick BerkovicLeen PaelinckKatrien VandecasteeleAkos GulybanCarlos De WagterBRUNO GODDEERISYolande Lievens

Whole breast and regional nodal irradiation in prone versus supine position in left sided breast cancer

Pieter DeseyneBruno SpeleersWilfried De NeveBert BouteLeen PaelinckTom Van HoofJoris Van de VeldeANNICK VAN GREVELINGChristel MontenGiselle Post et al.

A1 Journal Article in RADIATION ONCOLOGY

2016

Automated instead of manual planning for lung SBRT? A plan comparison based on dose-volume statistics

Barbara VanderstraetenBRUNO GODDEERISCRISTINA DERIEKatrien VandecasteeleMarc Van EijkerenLeen PaelinckCarlos De WagterYolande Lievens

The effect of the table top modeling on calculations and measurements for the Delta4 phantom

Leen PaelinckBarbara VanderstraetenRaju Prasad SrivastavaAna Maria Luiza OlteanuCarlos De Wagter

2015

Adaptive radiotherapy for locally advanced non-small cell lung cancer, can we predict when and for whom?

PATRICK BERKOVICLeen PaelinckYolande LievensAkos GulybanBRUNO GODDEERISCRISTINA DERIEVeerle SurmontWilfried De NeveKatrien Vandecasteele

A1 Journal Article in ACTA ONCOLOGICA

2013

Modeling the standard Elekta linear accelerator table top in a treatment planning system

Leen PaelinckBarbara VanderstraetenYolande LievensCarlos De Wagter

2012

Evaluation of a glassless photographic film scanner for high-gradient radiochromic film dosimetry

Annemieke De PuysseleyrRaju Prasad SrivastavaLeen PaelinckWilfried De NeveCarlos De Wagter

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

2009

Development of in vitro models for investigating spatially fractionated irradiation: physics and biological results

Stéphanie BlockhuysBarbara VanhoeckeLeen PaelinckMarc BrackeCarlos De Wagter

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Intensity-Modulated Arc Therapy with Simultaneous Integrated Boost in the Treatment of Primary Irresectable Cervical Cancer

Katrien VandecasteeleWilfried De NeveWerner De GersemLouke DelrueLeen PaelinckAmin MakarValérie FonteyneCarlos De WagterGeert VilleirsGert De Meerleer

A1 Journal Article in STRAHLENTHERAPIE UND ONKOLOGIE

The influence of small field sizes, penumbra, spot size and measurement depth on perturbation factors for microionization chambers

Frederik CropN ReynaertGEERT PITTOMVILSLeen PaelinckCarlos De WagterLuc VakaetHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

2008

Multi-dimensional dosimetric verification of stereotactic radiotherapy for uveal melanoma using radiochromic EBT film

Eva SturtewagenM FUSSLeen PaelinckCarlos De WagterD GEORG

A1 Journal Article in ZEITSCHRIFT FUR MEDIZINISCHE PHYSIK

On the calibration process of film dosimetry: OLS inverse regression versus WLS inverse prediction

Frederik CropBart Van RompayeLeen PaelinckLuc VakaetHubert ThierensCarlos De Wagter

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

2007

Monte Carlo modeling of the ModuLeaf miniature MLC for small field dosimetry and quality assurance of the clinical treatment planning system

Frederik CropNick ReynaertGEERT PITTOMVILSLeen PaelinckWerner De GersemCarlos De WagterLuc VakaetWilfried De NeveHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Precautions and strategies in using a commercial flatbed scanner for radiochromic film dosimetry

Leen PaelinckWilfried De NeveCarlos De Wagter

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Radiochromic EBT film dosimetry: Effect of film orientation and batch on the lateral correction of the scanner.

Leen PaelinckAN EBONGUEWilfried De NeveCarlos De Wagter

2006

2D-3D methods for clinical dose verification

Carlos De WagterLeen PaelinckYves De Deene

Accuracy of patient dose calculation for lung IMRT: A comparison of Monte Carlo, convolution/superposition, and pencil beam computations

Barbara VanderstraetenNick ReynaertLeen PaelinckIndira MadaniCarlos De WagterW GERSEMWilfried De NeveHubert Thierens

A1 Journal Article in MEDICAL PHYSICS

Accuracy of patient dose calculations for IMRT treatment of lung cancer

Barbara VanderstraetenNick ReynaertLeen PaelinckIndira MadaniWerner De GersemCarlos De WagterWilfried De NeveHubert Thierens

Comparison of dose-volume histograms of IMRT treatment plans for ethmoid sinus cancer computed by advanced treatment planning systems including Monte Carlo

Leen PaelinckBart De SmedtNick ReynaertMARC COGHEWerner De GersemCarlos De WagterBarbara VanderstraetenHubert ThierensWilfried De Neve

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

What precautions should we use with a flatbed scanner for radiochromic film dosimetry

Leen PaelinckCarlos De Wagter

2005

Comparison of build-up dose between Elekta and Varian linear accelerators for high-energy photon beams using radiochromic film and clinical implications for IMRT head and neck treatments

Leen PaelinckCarlos De WagterA VAN ESCHWIM DUTHOYT DEPUYDTWilfried De Neve

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Decoupling initial electron beam parameters for Monte Carlo photon beam modelling by removing beam-modifying filters from the beam path

Bart De SmedtNick ReynaertF FLACHETMARC COGHEMG THOMPSONLeen PaelinckGEERT PITTOMVILSCarlos De WagterWilfried De NeveHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Evaluation of the Sinmed Mastercouch (R) as replacement for a standard couch

Sofie GillisSamuel BralCarlos De WagterCRISTINA DERIELeen PaelinckK VAN VAERENBERGHMARC COGHEGert De MeerleerWilfried De Neve

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Experimental verification of lung dose with radiochromic film: comparison with Monte Carlo simulations and commercially available treatment planning systems

Leen PaelinckNick ReynaertHubert ThierensWilfried De NeveCarlos De Wagter

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

IMRT dose distributions for ethmoid sinus cancer calculated by five different treatment planning systems

Leen PaelinckBart De SmedtNick ReynaertMARC COGHEWerner De GersemCarlos De WagterBarbara VanderstraetenHubert ThierensWilfried De Neve

Optimization of the mean energy of the incident electron beam for MCTP by removing the beam-modifying filters from the linac head

Bart De SmedtNick ReynaertFemke FlachetMARC COGHELeen PaelinckGEERT PITTOMVILSJ SCHAUVLIEGECarlos De WagterWilfried De NeveHubert Thierens

The importance of accurate linear accelerator head modelling for IMRT Monte Carlo calculations

Nick ReynaertMARC COGHEBart De SmedtLeen PaelinckBarbara VanderstraetenWerner De GersemBART VAN DUYSECarlos De WagterWilfried De NeveHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

The magnetic resonance detected intraprostatic lesion in prostate cancer: planning and delivery of intensity-modulated radiotherapy

Gert De MeerleerGeert VilleirsS BRALLeen PaelinckWerner De GersemP DEKUYPERWilfried De Neve

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

The value of radiochromic film for IMRT verification in a head-and-neck phantom

Carlos De WagterLeen PaelinckSofie Gillis

2004

MCDE: a new Monte Carlo dose engine for IMRT

Nick ReynaertBart De SmedtMARC COGHELeen PaelinckBART VAN DUYSEWerner De GersemCarlos De WagterWilfried De NeveHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

2003

Application of monomer/polymer gel dosimetry to study the effects of tissue inhomogeneities on intensity-modulated radiation therapy (IMRT) dose distributions

Koen VergoteYves De DeeneF CLAUSWerner De GersemBART VAN DUYSELeen PaelinckEric AchtenWilfried De NeveC DE WAGER

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

The necessity of a divergent initial electron beam in the Monte-Carlo model of a linear accelerator

Bart De SmedtNick ReynaertMARC COGHELeen PaelinckB VAN DUYSSECarlos De WagterWilfried De NeveHubert Thierens

The value of radiochromic film dosimetry around air cavities: experimental results and Monte Carlo simulations

Leen PaelinckNick ReynaertHubert ThierensCarlos De WagterWilfried De Neve

The value of radiochromic film dosimetry around air cavities: experimental results and Monte Carlo simulations

Leen PaelinckNick ReynaertHubert ThierensCarlos De WagterWilfried De Neve

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

2002

Dosimetric verification as the ultimate QA test for the complete planning and delivery chain of IMRT.

Carlos De WagterK VERGOTEChantal MartensLeen PaelinckSofie GillisYves De DeeneWilfried De Neve

A4 Journal Article in Klinische Fysica