Research Explorer

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Researcher

Leander Van Neste

Awards & Distinctions

24 Results

2019

Evaluation of an epigenetic assay for predicting repeat prostate biopsy outcome in African American men

Robert L, Jr WaterhouseLeander Van NesteKelvin A MosesCarlton BarnswellJonathan L SilbersteinMark JalkutRonald TutroneJames SyloraRonald AngladeMyron Murdock et al.

A1 Journal Article in UROLOGY

2017

A four-gene promoter methylation marker panel consisting of GREM1, NEURL, LAD1, and NEFH predicts survival of clear cell renal cell cancer patients

Iris JH van VlodropSophie C JoostenTim De MeyerKim M SmitsLeander Van NesteVeerle MelotteMarcella MLL BaldewijnsLeo J SchoutenPiet A van den BrandtJana Jeschke et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

2014

Evaluation of different methods to assess homologous recombination status and sensitivity to PARP inhibitors in ovarian cancer

A MukhopadhyayM DixonE MulliganH SchuhwerkJ MurrayJ QuinnLeander Van NesteWim Van CriekingeN CurtinR Edmondson

2013

CD44 and OTP are strong prognostic markers for pulmonary carcinoids

Dorian RA SwartsMieke ER HenflingLeander Van NesteRobert Jan van SuylenAnne-Marie C DingemansWinand NM DinjensAnnick HaesevoetsMartina RudeliusErik ThunnissenMarco Volante et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

Clinical utility of an epigenetic assay to detect occult prostate cancer in histopathologically negative biopsies: results of the MATLOC study

Grant D StewartLeander Van NestePhilippe DelvennePaul DelréeAgnès DelgaS Alan McNeillMarie O'DonnellJames ClarkWim Van CriekingeJoseph Bigley et al.

A1 Journal Article in JOURNAL OF UROLOGY

2012

A tissue biopsy-based epigenetic multiplex PCR assay for prostate cancer detection

Leander Van NesteJoseph BigleyAdam TollGaëtan OttoJames ClarkPaul DelréeWim Van CriekingeJonathan I Epstein

A1 Journal Article in BMC UROLOGY

Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen

Jana JeschkeLeander Van NesteSabine C GlöcknerMashaal DhirMarilia Freitas CalmonValerie DeregowskiWim Van CriekingeIlse VlassenbroeckAlexander KochTimothy A Chan et al.

A1 Journal Article in EPIGENETICS

Genome‐wide RNA‐ and MBD‐sequencing in HCT116 and DKO cells as a global re‐expression model

Joachim De SchrijverGeert TrooskensLinda JW BoschPierre DehanBeatriz CarvalhoLeander Van NesteGerrit MeijerSteve BaylinWim Van Criekinge

The epigenetic promise for prostate cancer diagnosis.

Leander Van NesteJames G HermanGaëtan OttoJoseph W BigleyJonathan I EpsteinWim Van Criekinge

A1 Journal Article in PROSTATE

2010

Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells

Joyce E OhmPrashant MaliLeander Van NesteDavid M BermanLiang LiangKurinji PandiyanKimberley J BriggsWei ZhangPedram ArganiBrian Simons et al.

A1 Journal Article in CANCER RESEARCH

High content image cytometry in the context of subnuclear organization

Winnok De VosLeander Van NesteBirger DieriksGH JossPatric Van Oostveldt

A1 Journal Article in CYTOMETRY PART A

2009

Prognostic significance of Gremlin1 (GREM1) promoter CPG island hypermethylation in clear cell renal cell carcinoma

Iris JH van VlodropMarcella BaldewijnsKim SmitsLeo SchoutenLeander Van NesteWim Van CriekingeHein van PoppelEvelyne LerutNita AhujaJames Herman et al.

2008

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

L ChinM MeyersonK AldapeD BignerT MikkelsenS VandenBergA KahnR PennyML FergusonDS Gerhard et al.

A1 Journal Article in NATURE

Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis

TA CHANS GLOCKNERJM YIW CHENLeander Van NesteL COPEJG HERMANV VELCULESCUKE SCHUEBELN AHUJA et al.

A1 Journal Article in PLOS MEDICINE

Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells

KM MCGARVEYLeander Van NesteL COPEJE OHMJG HERMANNWim Van CriekingeKE SCHUEBELSB BAYLIN

A1 Journal Article in CANCER RESEARCH

Epigenetic inactivation of the canonical Wnt antagonist SRY-Box containing gene 17 in colorectal cancer

W ZHANGSC GLOCKNERMZ GUOEO MACHIDADH WANGH EASWARANLeander Van NesteJG HERMANKE SCHUEBELDN WATKINS et al.

A1 Journal Article in CANCER RESEARCH

In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia

K DE KEERSMAECKERI LAHORTIGAN MENTENSC FOLENSLeander Van NesteSofie BekaertP VANDENBERGHEMD ODEROP MARYNENJ COOLS

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

Methylation-induced silencing of TFPI-2 is an early-stage event in colorectal cancer

N AHUJAS GLOCKNERK SCHUEBELLeander Van NesteM VAN ENGELANDM DHIRK MCGARVEYS BAYLIN

Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3K4/K27 trimethylation

SD FOUSEY SHENM PELLEGRINIS COLEA MEISSNERLeander Van NesteR JAENISCHGP FAN

A1 Journal Article in CELL STEM CELL

Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25

M TESSEMAR WILLINKK DOYY YUW YUEO MACHIDAM BROCKLeander Van NesteCA STIDLEYSB BAYLIN et al.

A1 Journal Article in CANCER RESEARCH

PubMeth : a cancer methylation database combining text-mining and expert annotation

Maté OngenaertLeander Van NesteTim De MeyerGerben MenschaertSofie BekaertWim Van Criekinge

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Pubmeth: reviewed methylation database in cancer based on text-mining

Maté OngenaertLeander Van NesteTim De MeyerGerben MenschaertSofie BekaertWim Van Criekinge

2007

Comparing the DNA hypermethylome with gene mutations in human colorectal cancer

KE SCHUEBELW CHENL COPESC GLOCKNERH SUZUKIJM YITA CHANLeander Van NesteWim Van CriekingeS VAN DEN BOSCH et al.

A1 Journal Article in PLOS GENETICS

Relation between telomerase activity, hTERT and telomere length for intracranial tumours

Lode MaesLeander Van NesteK Van DammeJean-Pierre Kalala OkitoLeo De RidderSofie BekaertMaria Cornelissen

A1 Journal Article in ONCOLOGY REPORTS