Research Explorer

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Researcher

Leander Meuris

Publications & Research Data

Awards & Distinctions

33 Results

2025

A benchmark of DNA methylation deconvolution methods for tumoral fraction estimation using DecoNFlow

Edoardo GiuiliSofie Van de VeldeSam KintMaísa Renata Ferro Dos SantosLotte CornelliSofie RoelandtKathleen SchoofsRenske ImschootRuben Van PaemelLeander Meuris et al.

Collecting and analysing pig mucosal scraping samples for mass spectrometry-based proteomics : a study on factors causing variation in proteomic data

Hanne De RijckeAn StaesStefaan De SmetMarc HeyndrickxSam MilletLeander MeurisSimon DevosKris GevaertChristof Van Poucke

A1 Journal Article in JOURNAL OF PROTEOMICS

Design and evaluation of universal control antisense oligonucleotides across cellular models

Edith De BruyckerManon BouckaertEmma DelanoteLeander MeurisHanne LenaertsLode DenolfKatrien RemautAn StaesKris GevaertSteve Lefever et al.

Glycomics as prognostic biomarkers of hepatocellular carcinoma : a systematic review

Nicky SomersEmma ButayeLorenz GrossarNele PauwelsAnja GeertsSarah RaevensSander LefereLindsey DevisscherLeander MeurisNico Callewaert et al.

A1 Journal Article in ONCOLOGY LETTERS

Impact of IgG Fc glycosylation on disease dynamics in patients with primary Sjögren disease

Helena AchtenLeander MeurisLiselotte DerooMatthias JarlborgTine DecruyJoke DeprezEmilie DumasKristel De BoeckEva GenbruggeWouter Bauters et al.

A1 Journal Article in ARTHRITIS & RHEUMATOLOGY

Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of Pseudomonas aeruginosa in an organotypic 3-D lung epithelial cell model

Merel WautersLeander MeurisAurélie CrabbéXavier Saelens

Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of Pseudomonas aeruginosa in an organotypic 3D lung epithelial cell model

Merel WautersSara Van den BosscheLucia GrassiMariana Fernandes GonçalvesDelphi Van HaverSara DufourSimon DevosLeander MeurisFrancis ImpensXavier Saelens et al.

A1 Journal Article in VIRULENCE

2024

Advancing diagnosis and early risk assessment of preeclampsia through noninvasive cell-free DNA methylation profiling

Machteld BaetensBram Van GaeverStephanie DeblaereAndries De KokerLeander MeurisNico CallewaertSandra JanssensKristien RoelensEllen RoetsJo Van Dorpe et al.

A1 Journal Article in CLINICAL EPIGENETICS

Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge

M. N. PaschaMarlies BallegeerM. C. RoelofsLeander MeurisI. C. AlbulescuF. J. M. van KuppeveldD. L. HurdissB. J. BoschT. Zeev-Ben-MordehaiXavier Saelens et al.

A1 Journal Article in NPJ VACCINES

OPENPichia : licence-free Komagataella phaffii chassis strains and toolkit for protein expression

Katrien ClaesDries Van HerpeRobin VanlucheneCharlotte RoelsBerre Van MoerElise WyseureKristof VandewalleHannah EeckhautSemiramis YilmazSandrine Vanmarcke et al.

A1 Journal Article in NATURE MICROBIOLOGY

Pre-treatment serum N-glycans predict poor immunotherapy response and survival in hepatocellular carcinoma

Nicky SomersTheresa HoltmannFabian ArtusaEmma ButayeLorenz GrossarSarah RaevensAnja GeertsSander LefereLindsey DevisscherLeander Meuris et al.

Specific glycomic profiles can identify patients at risk of poor transplant-free survival in primary biliary cholangitis

Nicky SomersNikolaos GatselisMaria C. van HooffVasiliki LygouraEmma ButayeLorenz GrossarSarah RaevensAnja GeertsSander LefereLindsey Devisscher et al.

Systematic review : glycomics as diagnostic markers for hepatocellular carcinoma

Emma ButayeNicky SomersLorenz GrossarNele PauwelsSander LefereLindsey DevisscherSarah RaevensAnja GeertsLeander MeurisNico Callewaert et al.

A1 Journal Article in ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Therapy response monitoring in blood plasma from esophageal adenocarcinoma patients using cell-free DNA methylation profiling

Kathleen SchoofsMaísa Renata Ferro Dos SantosJilke De WildeSofie RoelandtSofie Van de VeldePhilippe DecruyenaereLeander MeurisOlivier ThasAnnouck PhilippronLieven Depypere et al.

A1 Journal Article in SCIENTIFIC REPORTS

2023

Glycomics-based serum markers as reliable tool for assessment of viral response after treatment with direct-acting antiviral drugs in hepatitis C virus infection

Nicky SomersElisabeth VandekerckhoveAnja GeertsHelena DegrooteSander LefereLindsey DevisscherLeander MeurisNico CallewaertHans Van VlierbergheXavier Verhelst

A1 Journal Article in ACTA CLINICA BELGICA

N-glycosylation engineering in chimeric antigen receptor T cells enhances anti-tumor activity

Elien De BousserNele FestjensLeander MeurisEvelyn PletsAnnelies Van HeckeElise WyseureStijn De MunterBart VandekerckhoveNico Callewaert

2022

Glycomics-based serum marker as reliable tool for assessment of viral response after treatment with direct-acting antiviral drugs in hepatitis C virus infection

Nicky SomersElisabeth VandekerckhoveAnja GeertsHelena DegrooteSander LefereLindsey DevisscherLeander MeurisNico CallewaertHans Van VlierbergheXavier Verhelst

Pretransplant alterations in serum protein glycosylation are associated to risk of hcc recurrence after liver transplantation and provide a potential prognostic biomarker : a proof-of-concept study

Xavier VerhelstHeleen EngelsAllison GeertsAude VanlanderLuis Abreu De CarvalhoHelena DegrooteLeander MeurisFrederik BerrevoetNico CallewaertHans Van Vlierberghe

Pretransplant changes in serum protein glycosylation relate to risk of HCC recurrence after liver transplantation and provide a potential prognostic biomarker : a proof-of-concept study

Xavier VerhelstHeleen EngelsAnja GeertsAude VanlanderLuis Abreu De CarvalhoHelena DegrooteLeander MeurisFrederik BerrevoetNico CallewaertHans Van Vlierberghe

Validation of a glycomics-based test associated with risk of HCC development in cirrhosis

Xavier VerhelstLeander MeurisRoos ColmanAnnelies Van HeckeAnja GeertsNico CallewaertHans Van Vlierberghe

2021

Epidermal galactose spurs chytrid virulence and predicts amphibian colonization

Yu WangElin VerbruggheLeander MeurisKoen ChiersMoira KellyDiederik StrubbeNico CallewaertFrank PasmansAn Martel

A1 Journal Article in NATURE COMMUNICATIONS

Serum glycomics on postoperative day 7 are associated with graft loss within 3 months after liver transplantation regardless of early allograft dysfunction

Xavier VerhelstAnja GeertsRoos ColmanAude VanlanderHelena DegrooteLuis Abreu De CarvalhoLeander MeurisFrederik BerrevoetXavier RogiersNico Callewaert et al.

A1 Journal Article in TRANSPLANTATION

2020

Human T cell glycosylation and implications on immune therapy for cancer

Elien De BousserLeander MeurisNico CallewaertNele Festjens

A1 Journal Article in HUMAN VACCINES & IMMUNOTHERAPEUTICS

Serum IGG-undergalactosylation profiles reflect cumulative exposure to systemic inflammation in spondyloarthritis patients

Ann-Sophie De CraemerZ. LukasikLeander MeurisLiselotte DerooThomas RensonManouk de HoogePhilippe CarronAnnelies Van HeckeNico CallewaertFilip Van den Bosch et al.

Structure and assembly mechanism of the signaling complex mediated by human CSF-1 (vol 23, pg 1621, 2015)

Jan FélixSteven De MunckKenneth VerstraeteLeander MeurisNico CallewaertJonathan ElegheertSavvas Savvides

2019

Customized protein glycosylation to improve biopharmaceutical function and targeting

Linde Van LanduytChiara LonigroLeander MeurisNico Callewaert

A1 Journal Article in CURRENT OPINION IN BIOTECHNOLOGY

2018

Endoglycosidase S enables a highly simplified clinical chemistry procedure for direct assessment of serum IgG undergalactosylation in chronic inflammatory disease

Dieter VanderschaegheLeander MeurisTom RaesHendrik GrootaertAnnelies Van HeckeXavier VerhelstFrederique Van de VeldeBruno LapauwHans Van VlierbergheNico Callewaert

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Mechanical strain determines the site-specific direction of inflammation and tissue damage in arthritis

Isabelle CambréDjoere GaublommeArne BurssensPeggy JacquesDirk ElewautR LoriesG SchettG KolliasAmélie De MuynckLeander Meuris et al.

Mechanical strain determines the site-specific direction of inflammation and tissue damage in arthritis

Isabelle CambréDorien GaublommeArne BurssensPeggy JacquesLeander MeurisStijn LambrechtShea CarterAmélie De MuynckNico CallewaertGeorge Kollias et al.

Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis

Isabelle CambréDjoere GaublommeArne BurssensPeggy JacquesNadia SchryversAmélie De MuynckLeander MeurisStijn LambrechtShea CarterPieter De Bleser et al.

A1 Journal Article in NATURE COMMUNICATIONS

2015

Structure and assembly mechanism of the signaling complex mediated by human CSF-1

Jan FélixSteven De MunckKenneth VerstraeteLeander MeurisNico CallewaertJonathan ElegheertSavvas Savvides

A1 Journal Article in STRUCTURE

2014

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

Yao-Cheng LinMorgane BooneLeander MeurisIrma LemmensNadine Van RoyArne SoeteJoke ReumersMatthieu MoisseStéphane PlaisanceRadoje Drmanac et al.

A1 Journal Article in NATURE COMMUNICATIONS

GlycoDelete engineering of mammalian cells simplifies N-glycosylation of recombinant proteins

Leander MeurisFrancis SantensGreg ElsonNele FestjensMorgane BooneAnaëlle Dos SantosSimon DevosFrançois RousseauEvelyn PletsErica Houthuys et al.

A1 Journal Article in NATURE BIOTECHNOLOGY