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Researcher
Leander Huyghe
Profile
Projects
Publications
Activities
Awards & Distinctions
6
Results
2024
High efficacy of huCD20-targeted AcTaferon in humanized patient derived xenograft models of aggressive B cell lymphoma
Willem Daneels
Alexander Van Parys
Leander Huyghe
Elke Rogge
Steffi De Rouck
Ruben Christiaen
Lennart Zabeau
Sylvie Taveirne
Jo Van Dorpe
Niko Kley
et al.
A1
Journal Article
in
EXPERIMENTAL HEMATOLOGY & ONCOLOGY
2024
2021
Selective IL-1 activity on CD8+ T cells empowers antitumor immunity and synergizes with neovasculature-targeted TNF for full tumor eradication
Bram Van Den Eeckhout
Leander Huyghe
Sandra Van Lint
Elianne Burg
Stéphane Plaisance
Frank Peelman
Anje Cauwels
Gilles Uzé
Niko Kley
Sarah Gerlo
et al.
A1
Journal Article
in
JOURNAL FOR IMMUNOTHERAPY OF CANCER
2021
2020
Safe eradication of large established tumors using neovasculature-targeted tumor necrosis factor-based therapies
Leander Huyghe
Alexander Van Parys
Anje Cauwels
Sandra Van Lint
Stijn De Munter
Jennyfer Bultinck
Lennart Zabeau
Jeroen Hostens
An Goethals
Nele Vanderroost
et al.
A1
Journal Article
in
EMBO MOLECULAR MEDICINE
2020
2014
ARGX-110, a highly potent antibody targeting CD70, eliminates tumors via both enhanced ADCC and immune checkpoint blockade
Karen Silence
Torsten Dreier
Mahan Moshir
Peter Ulrichts
Sofie ME Gabriels
Michael Saunders
Harald Wajant
Peter Brouckaert
Leander Huyghe
Tim Van Hauwermeiren
et al.
A1
Journal Article
in
MABS
2014
Influence of cinaciguat on gastrointestinal motility in apo-sGC mice
Sarah Cosyns
Leander Huyghe
Robrecht Thoonen
Johannes-Peter Stasch
Peter Brouckaert
Romain Lefebvre
A1
Journal Article
in
NEUROGASTROENTEROLOGY AND MOTILITY
2014
2008
Study of molecular and immunological factors that determine the sensitivity to the antitumor effect of Tumor Necrosis Factor
Leander Huyghe
P Brouckaert
Dissertation
2008