Research Explorer

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Researcher

Leander Huyghe

Awards & Distinctions

5 Results

2021

Selective IL-1 activity on CD8+ T cells empowers antitumor immunity and synergizes with neovasculature-targeted TNF for full tumor eradication

Bram Van Den EeckhoutLeander HuygheSandra Van LintElianne BurgStéphane PlaisanceFrank PeelmanAnje CauwelsGilles UzéNiko KleySarah Gerlo et al.

A1 Journal Article in JOURNAL FOR IMMUNOTHERAPY OF CANCER

2020

Safe eradication of large established tumors using neovasculature-targeted tumor necrosis factor-based therapies

Leander HuygheAlexander Van ParysAnje CauwelsSandra Van LintStijn De MunterJennyfer BultinckLennart ZabeauJeroen HostensAn GoethalsNele Vanderroost et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

2014

ARGX-110, a highly potent antibody targeting CD70, eliminates tumors via both enhanced ADCC and immune checkpoint blockade

Karen SilenceTorsten DreierMahan MoshirPeter UlrichtsSofie ME GabrielsMichael SaundersHarald WajantPeter BrouckaertLeander HuygheTim Van Hauwermeiren et al.

A1 Journal Article in MABS

Influence of cinaciguat on gastrointestinal motility in apo-sGC mice

Sarah CosynsLeander HuygheRobrecht ThoonenJohannes-Peter StaschPeter BrouckaertRomain Lefebvre

A1 Journal Article in NEUROGASTROENTEROLOGY AND MOTILITY

2008

Study of molecular and immunological factors that determine the sensitivity to the antitumor effect of Tumor Necrosis Factor

Leander HuygheP Brouckaert