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Researcher
Laurens Lambrechts
Profile
Projects
Publications
Activities
Awards & Distinctions
27
Results
2024
Development of a novel assay to characterize the HIV-1 reservoir using long-read sequencing
Laurens Lambrechts
Linos Vandekerckhove
Wim Van Criekinge
Dissertation
2024
2023
HIV-PULSE : a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization
Laurens Lambrechts
Noah Bonine
Rita Verstraeten
Marion Pardons
Ytse Noppe
Sofie Rutsaert
Filip Van Nieuwerburgh
Wim Van Criekinge
Basiel Cole
Linos Vandekerckhove
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2023
HIV-PULSE : a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization
Laurens Lambrechts
Noah Bonine
Rita Verstraeten
Marion Pardons
Ytse Noppe
Sofie Rutsaert
Filip Van Nieuwerburgh
Wim Van Criekinge
Basiel Cole
Linos Vandekerckhove
Preprint
2023
In-depth assessment of the HIV-1 viral reservoir in early treated individuals
Tine Struyve
Marion Pardons
Liesbet Termote
Jozefien De Clercq
Laurens Lambrechts
Jerel Vega
Daniel Boden
Mathias Lichterfeld
Sofie Rutsaert
Linos Vandekerckhove
C3
Conference
2023
Linking inducible HIV-1 reservoir to rebound after treatment interruption
Laurens Lambrechts
Ytse Noppe
Marion Pardons
Basiel Cole
Sofie Rutsaert
Stéphane De Wit
Guido Vanham
Eric Florence
Linos Vandekerckhove
C3
Conference
2023
Optimization of a long-read sequencing assay for near full-length HIV-1 proviral genome characterization
Sofie De Braekeleer
Laurens Lambrechts
Sofie Rutsaert
Linos Vandekerckhove
C3
Conference
2023
Optimization of a long-read sequencing assay for near full-length HIV-1 proviral genome characterization to enhance read accuracy
Sofie De Braekeleer
Laurens Lambrechts
Sofie Rutsaert
Linos Vandekerckhove
C3
Conference
2023
Potent latency reversal by Tat RNA-containing nanoparticle enables multi-omic analysis of the HIV-1 reservoir
Marion Pardons
Basiel Cole
Laurens Lambrechts
Willem van Snippenberg
Sofie Rutsaert
Ytse Noppe
Nele De Langhe
Annemieke Dhondt
Jerel Vega
Filmon Eyassu
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2023
The Rainbow 5-plex digital PCR assay improves quantification of the viral reservoir resulting in a better understanding of the HIV-1 proviral landscape
Mareva Delporte
Laurens Lambrechts
Marion Pardons
Sofie De Braekeleer
Evy Blomme
Sofie Rutsaert
Wim Trypsteen
Linos Vandekerckhove
C3
Conference
2023
Unraveling ongoing inflammation after early ART by in-depth analysis of lymph nodes
Jozefien De Clercq
Kathleen Busman-Sahay
Laurens Lambrechts
Sofie Rutsaert
Sol Taylor-Brill
Stephen Bondoc
Marie-Angélique De Scheerder
Jacob Estes
Sarah Gerlo
Linos Vandekerckhove
C3
Conference
2023
2022
Characterization of the HIV-1 viral reservoir in subtype B early treated individuals
Tine Struyve
Marion Pardons
Liesbet Termote
Jozefien De Clercq
Laurens Lambrechts
Jerel Vega
Daniel Boden
Mathias Lichterfeld
Sofie Rutsaert
Linos Vandekerckhove
C3
Conference
2022
Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruption
Basiel Cole
Laurens Lambrechts
Zoe Boyer
Ytse Noppe
Marie-Angélique De Scheerder
John-Sebastian Eden
Bram Vrancken
Timothy E. Schlub
Sherry McLaughlin
Lisa M. Frenkel
et al.
A1
Journal Article
in
CELL REPORTS
2022
Long-read sequencing assay allows accurate characterization of the HIV-1 reservoir
Laurens Lambrechts
Rita Verstraeten
Noah Bonine
Ytse Noppe
Sofie Rutsaert
Marion Pardons
Basiel Cole
Linos Vandekerckhove
C3
Conference
2022
Long-read sequencing assay allows accurate characterization of the HIV-1 reservoir
Laurens Lambrechts
Rita Verstraeten
Noah Bonine
Ytse Noppe
Sofie Rutsaert
Marion Pardons
Basiel Cole
Linos Vandekerckhove
C3
Conference
2022
Long-read sequencing assay allows accurate characterization of the HIV-1 reservoir
Laurens Lambrechts
Rita Verstraeten
Noah Bonine
Ytse Noppe
Marion Pardons
Basiel Cole
Linos Vandekerckhove
C3
Conference
2022
Two years of genomic surveillance in Belgium during the SARS-CoV-2 pandemic to attain country-wide coverage and monitor the introduction and spread of emerging variants
Lize Cuypers
Simon Dellicour
Samuel L. Hong
Barney I. Potter
Bruno Verhasselt
Nick Vereecke
Laurens Lambrechts
Keith Durkin
Vincent Bours
Sofieke Klamer
et al.
A1
Journal Article
in
VIRUSES-BASEL
2022
Unraveling persistent inflammation after very early ART through in-depth analysis of lymph nodes
Jozefien De Clercq
Kathleen Busman-Sahay
Laurens Lambrechts
Sofie Rutsaert
Stephen Bondoc
Sol Taylor-Brill
Marie-Angélique De Scheerder
Jacob Estes
Sarah Gerlo
Linos Vandekerckhove
C3
Conference
2022
2021
In-depth characterization of HIV-1 reservoirs reveals links to viral rebound during treatment interruption
Basiel Cole
Laurens Lambrechts
Zoe Boyer
Ytse Noppe
Marie-Angélique De Scheerder
John-Sebastian Eden
Bram Vrancken
Timothy Schlub
Sherry McLaughlin
Lisa M. Frenkel
et al.
Preprint
2021
In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of plasma viremia
Basiel Cole
Laurens Lambrechts
Pierre Gantner
Ytse Noppe
Noah Bonine
Wojciech Witkowski
Lennie Chen
Sarah Palmer
James I. Mullins
Nicolas Chomont
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2021
In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of residual viremia and rebound viruses
Basiel Cole
Laurens Lambrechts
Pierre Gantner
Ytse Noppe
Noah Bonine
Lennie Chen
Sarah Palmer
James Mullins
Nicolas Chomont
Marion Pardons
et al.
C3
Conference
2021
Organ-specific genome diversity of replication-competent SARS-CoV-2
Jolien Van Cleemput
Willem van Snippenberg
Laurens Lambrechts
Amélie Dendooven
Valentino D'Onofrio
Liesbeth Couck
Wim Trypsteen
Jan Vanrusselt
Sebastiaan Theuns
Nick Vereecke
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2021
PCIP-seq : simultaneous sequencing of integrated viral genomes and their insertion sites with long reads
Maria Artesi
Vincent Hahaut
Basiel Cole
Laurens Lambrechts
Fereshteh Ashrafi
Ambroise Marçais
Olivier Hermine
Philip Griebel
Natasa Arsic
Frank van der Meer
et al.
A1
Journal Article
in
GENOME BIOLOGY
2021
2020
Combined assays shed new light on HIV-1 proviral sequence and linked integration site
Basiel Cole
Laurens Lambrechts
Maria Artesi
Vincent Hahaut
Wojciech Witkowski
Ytse Noppe
Annemieke Dhondt
Keith Durkin
Anne Van den Broeke
Linos Vandekerckhove
C3
Conference
2020
Emerging PCR-based techniques to study HIV-1 reservoir persistence
Laurens Lambrechts
Basiel Cole
Sofie Rutsaert
Wim Trypsteen
Linos Vandekerckhove
A1
Journal Article
in
VIRUSES-BASEL
2020
Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020
Erik Alm
Eeva K Broberg
Thomas Connor
Emma B Hodcroft
Andrey B Komissarov
Sebastian Maurer-Stroh
Angeliki Melidou
Richard A Neher
Áine O’Toole
Dmitriy Pereyaslov
et al.
A1
Journal Article
in
EUROSURVEILLANCE
2020
The elusive source of HIV-1 rebound after treatment interruption
Laurens Lambrechts
Basiel Cole
Marie-Angélique De Scheerder
Zoe Boyer
Ytse Noppe
Katie Fisher
John-Sebastian Eden
Wim Van Criekinge
Lisa Frenkel
Sarah Palmer
et al.
C3
Conference
2020
2019
The potential of long-read sequencing by MinION in the setting of a diverse genetic background of HIV-1
Laurens Lambrechts
C3
Conference
2019