Research Explorer

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Researcher

Laurens De Coen

Awards & Distinctions

21 Results

2020

A Vilsmeier chloroformylation by continuous flow chemistry

Manuel Carrera FernandezLaurens De CoenMichelle CoppensWim DermautChristian Stevens

A1 Journal Article in ORGANIC PROCESS RESEARCH & DEVELOPMENT

2019

Continuous-flow synthesis of phenothiazine antipsychotics : a feasibility study

Marine MovsisyanLaurens De CoenThomas HeugebaertArno VerleeBart RomanChristian Stevens

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis and preliminary biological evaluation of furo- and oxazolopyrimidines

Laurens De CoenChristian Stevens

2018

Green synthesis of highly functionalized octahydropyrrolo[3,4-c]pyrrole derivatives using subcritical water, and their anti(myco)bacterial and antifungal activity

Yahya NuralMuge GemiliErdal YabalakLaurens De CoenMahmut Ulger

A1 Journal Article in ARKIVOC

Synthesis and biological activity of oxazolopyrimidines

Laurens De CoenBart RomanMarine MovsisyanThomas HeugebaertChristian Stevens

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis, antimicrobial activity and acid dissociation constants of methyl 5,5-diphenyl-1-(thiazol-2-yl)pyrrolidine-2-carboxylate derivatives

Yahya NuralMuge GemiliMahmut UlgerHayati SariLaurens De CoenErtan Sahin

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

2017

A new class of bicyclic dicationic salts based on the 7-azoniabicyclo[2.2.1]heptane scaffold

Laurens De CoenBart RomanMarine MovsisyanBrecht D'hontNils De VosKristof Van HeckeChristian Stevens

A1 Journal Article in TETRAHEDRON LETTERS

Synthesis of 7-azoniabicyclo[2.2.1]heptane-based dicationic liquids

Laurens De CoenBart RomanBrecht D'hontNils De VosKristof Van HeckeChristian Stevens

2015

Microbial inhibition of oral epithelial wound recovery: potential role for quorum sensing molecules?

Tine De RyckEline VanlanckerCharlotte GrootaertBart RomanLaurens De CoenIsabel VandenbergheChristian StevensMarc BrackeTom Van de WieleBarbara Vanhoecke

A1 Journal Article in AMB EXPRESS

Straightforward synthesis of functionalized furo[3,4-d] pyrimidine-2,4-diones

Laurens De CoenMartyna JatczakKoen MuylaertSven MangelinckxChristian Stevens

A1 Journal Article in SYNTHESIS-STUTTGART

Synthetic entries to and biological activity of pyrrolopyrimidines

Laurens De CoenThomas HeugebaertDaniel Garcia JimenezChristian Stevens

A1 Journal Article in CHEMICAL REVIEWS

2014

Feruloyl benzotriazole and Weinreb amide as bioinspired building blocks: a reactivity study

Bart RomanJean-Christophe MonbaliuLaurens De CoenSigrid VerhasseltChristian Stevens

Feruloylbenzotriazole and Weinreb amide as bioinspired building blocks: a reactivity study towards O-, N-, S-, and C- nucleophiles

Bart RomanJean-Christophe MonbaliuLaurens De CoenSigrid VerhasseltBart SchuddinckEvelien Van HoeylandtChristian Stevens

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Straightforward entry to pyrido[2,3-d]pyrimidine-2,4(1H,3H)-diones and their ADME properties

Martyna JatczakKoen MuylaertLaurens De CoenJanneke KeeminkBenjamin WuytsPatrick AugustijnsChristian Stevens

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Straightforward synthesis of furo[3,4-d]pyrimidine-2,4-diones

Laurens De CoenMartyna JatczakKoen MuylaertSven MangelinckxChristian Stevens

Synthesis and early ADME evaluation of a novel scaffold, tetrahydro-6H-pyrido[3,2-b]azepin-6-one

Koen MuylaertMartyna JatczakBenjamin WuytsLaurens De CoenKristof Van HeckeHans LoonesJanneke KeeminkDaniel Garcia JimenezSven MangelinckxPieter Annaert et al.

A1 Journal Article in SYNLETT

The Cu(OTf)2 catalysed microwave assisted synthesis of a new scaffold, 7-aryl-7,8-dihydropyrido[4,3-c]pyridazin-5(6H)-one

Koen MuylaertSven MangelinckxMartyna JatczakLaurens De CoenKristof Van HeckeChristian Stevens

A1 Journal Article in ARKIVOC

2013

Design, synthesis and structure-activity relationships of some novel, highly potent anti-invasive (E)- and (Z)-stilbenes

Bart RomanLaurens De CoenSéverine MortierTine De RyckBarbara VanhoeckeAlan R KatritzkyMarc BrackeChristian Stevens

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Feruloyl benzotriazole and Weinreb amide as bioinspired building blocks: a reactivity study

Bart RomanJean-Christophe MonbaliuLaurens De CoenSigrid VerhasseltChristian Stevens

Straightforward microwave-assisted synthesis of 5,8-disubstituted 5,6,8,9-tetrahydro-4H,7H-2,5,6a,8,9a-pentaazaphenalene-1,3-diones

Daniel Garcia JimenezMartyna JatczakKoen MuylaertLaurens De CoenChristian Stevens

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

2012

Straightforward microwave-assisted synthesis of tricyclic 5,8-disubstituted-5,6,8,9-tetrahydro-4H,7H-2,5,6a,8,9a-pentaazaphenalene-1,3-dione

Daniel Garcia JimenezLaurens De CoenChristian Stevens