Research Explorer

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Researcher

Laura Van Moortel

Awards & Distinctions

12 Results

2025

Exploring protein conformations with limited proteolysis coupled to mass spectrometry

Chloé Van LeeneLaura Van MoortelKarolien De BosscherKris Gevaert

A1 Journal Article in TRENDS IN BIOCHEMICAL SCIENCES

Maximizing immunopeptidomics-based bacterial epitope discovery by multiple search engines and rescoring

Patrick WillemsFabien Henri TheryLaura Van MoortelMargaux De MeyerAn StaesAdillah GulLyudmila KovalchukeArthur DeclercqRobbe DevreeseRobbin Bouwmeester et al.

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

2024

Glucocorticoid receptor signaling : intricacies and therapeutic opportunities

Dorien ClarisseLaura Van MoortelChloé Van LeeneKris GevaertKarolien De Bosscher

A1 Journal Article in TRENDS IN BIOCHEMICAL SCIENCES

Immunopeptidomics mapping of Listeria monocytogenes T cell epitopes in mice

Adillah GulLecia L. PewePatrick WillemsRupert MayerFabien Henri TheryCaroline AsselmanIlke AernoutRein VerbekeDenzel EggermontLaura Van Moortel et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomics

Louis DelhayeGeorgios MoschonasDaria FijalkowskaAnnick VerheeDelphine De SutterTessa Van de SteeneMargaux De MeyerHanna GrzesikLaura Van MoortelKarolien De Bosscher et al.

A2 Journal Article in CELL REPORTS METHODS

Selective modulation of the human glucocorticoid receptor compromises GR chromatin occupancy and recruitment of p300/CBP and the Mediator complex

Laura Van MoortelAnnick VerheeJonathan ThommisRené HoutmanDiana MelchersLouis DelhayeChloé Van LeeneMadeleine HellemansKris GevaertSven Eyckerman et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

2023

The biologist’s guide to the glucocorticoid receptor’s structure

Nick DeploeyLaura Van MoortelInez RogatskyFrank PeelmanKarolien De Bosscher

A1 Journal Article in CELLS

The quest for improved ligands : a study of the functional plasticity of the glucocorticoid receptor

Laura Van MoortelKarolien De BosscherKris Gevaert

2022

Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets

Laura Van MoortelJonathan ThommisBrecht MaertensAn StaesDorien ClarisseDelphine De SutterClaude LibertOnno C. MeijerSven EyckermanKris Gevaert et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

2020

Improved glucocorticoid receptor ligands : fantastic beasts, but how to find them?

Laura Van MoortelKris GevaertKarolien De Bosscher

A1 Journal Article in FRONTIERS IN ENDOCRINOLOGY

2017

Compound A influences gene regulation of the dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment

Sofie DesmetNadia BougarneLaura Van MoortelLode De CauwerJonathan ThommisM VuylstekeDariusz RatmanR HoutmanJan TavernierKarolien De Bosscher

A1 Journal Article in SCIENTIFIC REPORTS

2016

Endothelial response to glucocorticoids in inflammatory diseases

Karolina A ZielińskaLaura Van MoortelGhislain OpdenakkerKarolien De BosscherPhilippe E Van den Steen

A1 Journal Article in FRONTIERS IN IMMUNOLOGY