Research Explorer

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Researcher

Laura Kiekens

7 Results

2022

IRF2 is required for development and functional maturation of human NK cells

Eva PersynSigrid WahlenLaura KiekensWouter Van LoockeHannah SiweEls Van AmmelZenzi De VosFilip Van NieuwerburghTom TaghonBart VandekerckhovePieter Van VlierbergheGeorges Leclercq

U Journal Article in Frontiers in Immunology

T-BET and EOMES : the powerful pair in human NK cell differentiation and ILC3 plasticity

Laura KiekensGeorges Leclercq

T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells

Laura KiekensSigrid WahlenEva PersynZenzi De VosTom TaghonBart VandekerckhoveGeorges Leclercq

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

TXNIP promotes human NK cell development but is dispensable for NK cell functionality

Eva PersynSigrid WahlenLaura KiekensSylvie TaveirneWouter Van LoockeEls Van AmmelFilip Van NieuwerburghTom TaghonBart VandekerckhovePieter Van VlierbergheGeorges Leclercq

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

Sigrid WahlenFilip MatthijssensWouter Van LoockeSylvie TaveirneLaura KiekensEva PersynEls Van AmmelZenzi De VosStijn De MunterFilip Van NieuwerburghTom TaghonBart VandekerckhovePieter Van VlierbergheGeorges Leclercq

A1 Journal Article in ELIFE

2021

T-BET and EOMES accelerate and enhance functional differentiation of human natural killer cells

Laura KiekensWouter Van LoockeSylvie TaveirneSigrid WahlenEva PersynEls Van AmmelZenzi De VosFilip Van NieuwerburghTom TaghonPieter Van VlierbergheBart VandekerckhoveGeorges Leclercq

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2020

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

Sylvie TaveirneSigrid WahlenWouter Van LoockeLaura KiekensEva PersynEls Van AmmelKatrien De MulderJuliette RoelsLaurentijn TillemanFilip Van NieuwerburghTessa KerreTom TaghonPieter Van VlierbergheBart VandekerckhoveGeorges Leclercq

A1 Journal Article in BLOOD