Research Explorer

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Researcher

Laura Dhondt

Awards & Distinctions

15 Results

2022

Reliability of glomerular filtration rate estimating formulas compared to iohexol plasma clearance in critically ill children

Evelyn DhontCharlotte WindelsEvelien SnauwaertTatjana Van Der HeggenAnnik de JaegerLaura DhondtJoris DelangheSiska CroubelsJohan Vande WallePeter De Paepe et al.

A1 Journal Article in EUROPEAN JOURNAL OF PEDIATRICS

2021

The development of a juvenile porcine augmented renal clearance model through continuous infusion of lipopolysaccharides : an exploratory study

Laura DhondtSiska CroubelsRobin TemmermanPieter De CockEvelyne MeyerWim Van Den BroeckPeter De PaepeMathias Devreese

A1 Journal Article in FRONTIERS IN VETERINARY SCIENCE

Unraveling the contribution of fluid therapy to the development of augmented renal clearance in a piglet model

Laura DhondtSiska CroubelsPeter De PaepeKlara GoethalsPieter De CockMathias Devreese

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Volumetric absorptive microsampling as alternative sampling technique for renal function assessment in the paediatric population using iohexol

Laura DhondtSiska CroubelsPieter De CockEvelyn DhontSiegrid De BaerePeter De PaepeMathias Devreese

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

2020

Conventional pig as animal model for human renal drug excretion processes : unravelling the porcine renal function by use of a cocktail of exogenous markers

Laura DhondtSiska CroubelsPeter De PaepeSteven C. WallisSaurabh PandeyJason A. RobertsJeffrey LipmanPieter De CockMathias Devreese

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Grasping the phenomenon of augmented renal clearance in the critically ill using the conventional pig as juvenile animal model

Laura DhondtMathias DevreeseSiska CroubelsPeter De PaepePieter De Cock

Simultaneous measurement of glomerular filtration rate, effective renal plasma flow and tubular secretion in different poultry species by single intravenous bolus of iohexol and para-aminohippuric acid

Lenka StroobantSiska CroubelsLaura DhondtJoske MillecamSiegrid De BaereElke GasthuysJ MorrensGunther Antonissen

A1 Journal Article in ANIMALS

2019

Development and validation of an ultra-high performance liquid chromatography-tandem mass spectrometry method for the simultaneous determination of iohexol, p-aminohippuric acid and creatinine in porcine and broiler chicken plasma

Laura DhondtSiska CroubelsPieter De CockPeter De PaepeSiegrid De BaereMathias Devreese

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Piglets as animal model to assess the contribution of fluid therapy to the development of augmented renal clearance in children

Laura DhondtSiska CroubelsPeter De PaepePieter De CockMathias Devreese

Target attainment of amikacin therapy in critically ill children

Joery VerbruggenKamilya JakipbayevaEvelyn DhontLaura DhondtTatjana Van Der HeggenINGRID HERCKJohan Vande WallePeter De PaepePieter De Cock

The juvenile pig as animal model for unraveling renal drug elimination processes in children

Laura DhondtSiska CroubelsPeter De PaepePieter De CockMathias Devreese

2018

Simultaneous determination of creatinine, iohexol and p-aminohippuric acid in animal plasma by ultra-high-performance liquid chromatography-tandem mass spectrometry

Laura DhondtSiska CroubelsPieter De CockPeter De PaepeMathias Devreese

The development of a juvenile porcine augmented renal clearance model for paediatric drug research during sepsis : the effect of different continuously administered LPS doses on the renal function

Laura DhondtSiska CroubelsPieter De CockPeter De PaepeMathias Devreese

2017

Comparative population pharmacokinetics and absolute oral bioavailability of COX-2 selective inhibitors celecoxib, mavacoxib and meloxicam in cockatiels (Nymphicus hollandicus)

Laura DhondtMathias DevreeseSiska CroubelsSiegrid De BaereRoel HaesendonckTess GoessensRonette GehringPatrick De BackerGunther Antonissen

A1 Journal Article in SCIENTIFIC REPORTS

The use of population pharmacokinetics for pharmacokinetic studies in small and exotic avian species : the case of celecoxib, mavacoxib and meloxicam in cockatiels (Nymphicus hollandicus)

Laura DhondtMathias DevreeseSiska CroubelsSiegrid De BaereRoel HaesendonckTess GoessensRonette GehringPatrick De BackerGunther Antonissen