Research Explorer

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Researcher

Lara Derycke

Publications & Research Data

Awards & Distinctions

67 Results

2026

Mechanisms and kinetics of wound healing in chronic rhinosinusitis patients after complete sinus surgery and its improvement by doxycycline therapy

Elke VandewalleEls De SchryverLien CalusManon BlauwblommePauline JanssenEllen KetelaereSharon Van NevelAnne-Sophie EeckelsNatalie De RuyckGabriële Holtappels et al.

A1 Journal Article in INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY

2025

Nasal mucosal brushings could be used to define the endotype in nasal inflammatory diseases

Elke VandewalleGabriële HoltappelsNatalie De RuyckLara DeryckeManon BlauwblommeEllen KetelaereAnne-Sophie EeckelsThibaut Van ZeleStijn VanheePhilippe Gevaert

Real-life effectiveness of mepolizumab and omalizumab in sever uncontrolled chronic rhinosinusitis with nasal polyps : a prospective study

Manon BlauwblommePhilippe GevaertGuy BrusselleGeert De VosAnne-Sophie EeckelsStijn VanheeElke VandewalleGabriële HoltappelsNatalie De RuyckEllen Ketelaere et al.

2024

Case report : dual monoclonal antibody therapy in chronic rhinosinusitis with nasal polyps and severe eosinophilic asthma : a proteome analysis

Manon BlauwblommePhilippe GevaertSharon Van NevelSebastian RiemannElke VandewalleGabriële HoltappelsNatalie De RuyckLara DeryckeAnne-Sophie EeckelsStijn Vanhee et al.

A2 Journal Article in FRONTIERS IN ALLERGY

2023

Olfaction in nasal polyp patients after Reboot surgery : an endotype-based prospective study

Sara Costa GomesTim DelemarreGabriële HoltappelsThibaut Van ZeleLara DeryckeEllen BonneAnne-Sophie EeckelsNan ZhangRichard Louis VoegelsClaus Bachert

A1 Journal Article in EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

2020

Functional characterization of the first missense variant in CEP78, a founder allele associated with cone‐rod dystrophy, hearing loss and reduced male fertility

Giulia AscariFrank PeelmanPietro FarinelliToon RosseelNina LambrechtsKirsten A. WunderlichMatias WagnerKonstantinos NikopoulosPernille MartensIrina Balikova et al.

A1 Journal Article in HUMAN MUTATION

2019

Expansion of the role and functional characterization of a missense variant in CEP78 associated with cone-rod dystrophy and hearing loss

Giulia AscariFrank PeelmanPietro FarinelliToon RosseelNina LambrechtsIrina BalikovaLara DeryckeGabriële HoltappelsOlga KryskoThalia Van Laethem et al.

Immunologic mechanisms of a short-course of Lolium perenne peptide immunotherapy : a randomized, double-blind, placebo-controlled trial

Hanisah SharifIesha SinghLubna KouserRalph MösgesMarie-Alix BonnyAngeliki KaramaniRebecca V ParkinNicolas BovyUday KishoreAbigail Robb et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps

Y ZhangLara DeryckeGabriële HoltappelsXD WangL ZhangClaus BachertNan Zhang

A1 Journal Article in ALLERGY

2018

FcεRI expression and IgE binding by dendritic cells and basophils in allergic rhinitis and upon allergen immunotherapy

Margot BeringsPhilippe GevaertNatalie De RuyckLara DeryckeGabriële HoltappelsC PiletteClaus BachertBart LambrechtMelissa Dullaers

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

2017

Alcohol hyper-responsiveness in chronic rhinosinusitis with nasal polyps

Els De SchryverLara DeryckePaloma CampoEline GabrielsGuy JoosThibaut Van ZeleClaus BachertPeter W HellingsPhilippe Gevaert

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

IL-21 is increased in nasal polyposis and after stimulation with Staphylococcus aureus enterotoxin B

Lien CalusLara DeryckeMelissa DullaersThibaut Van ZeleNatalie De RuyckClaudina Perez NovoGabriële HoltappelsGeert De VosBart LambrechtClaus Bachert et al.

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Missense mutation in CEP78 in a family with cone-rod dystrophy, sensorineural hearing loss, obesity and subfertility

Giulia AscariStijn Van de SompeleLara DeryckeGabriële HoltappelsOlga KryskoJo Van DorpeDavid CreytensThalia Van LaethemIrina BalikovaJan Gerris et al.

Missense mutation in CEP78 in a family with cone-rod dystrophy, sensorineural hearing loss, obesity and subfertility.

Giulia AscariStijn Van de SompeleLara DeryckeGabriële HoltappelsOlga KryskoJo Van DorpeDavid CreytensThalia Van LaethemIrina BalikovaJan Gerris et al.

Probiotics-impregnated bedding covers for house dust mite allergic rhinitis : a pilot randomized clinical trial

Margot BeringsAnton JultHanne VermeulenNatalie De RuyckLara DeryckeH UcarP GhekiereR TemmermanJ EllisClaus Bachert et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Probiotics-impregnated bedding covers in house dust mite allergic rhinitis patients : a double-blind, randomised, placebo-controlled, crossover clinical trial

Margot BeringsAnton JultHans VermeulenNatalie De RuyckLara DeryckeH. UcarP. GhekiereR. TemmermanJ. EllisClaus Bachert et al.

Suppression of allergen-induced basophil activation upon treatment with subcutaneous house dust mite immunotherapy: a prospective study

Margot BeringsNatalie De RuyckLara DeryckeGabriële HoltappelsClaus BachertBart LambrechtMelissa DullaersPhilippe Gevaert

The effect of systemic treatments on periostin expression reflects their interference with the eosinophilic inflammation in chronic rhinosinusitis with nasal polyps

Emile De SchryverLara DeryckeLIEN CALUSGabriële HoltappelsPeter HellingsThibaut Van ZeleClaus BachertPhilippe Gevaert

A1 Journal Article in RHINOLOGY

2016

Local periostin in chronic rhinosinusitis with nasal polyps : comparison of different medical treatment options

Els De SchryverLien CalusLara DeryckeThibaut Van ZeleClaus BachertPhilippe Gevaert

Systemic expression of inflammatory mediators in patients with chronic rhinosinusitis and nasal polyps with and without Aspirin Exacerbated Respiratory Disease

Rogerio PezatoMonika Świerczyńska-KrępaEwa Niżankowska-MogilnickaGabriële HoltappelsNatalie De RuyckMarek SanakLara DeryckeKoen Van CrombruggenClaus BachertClaudina Perez Novo

A1 Journal Article in CYTOKINE

The quest for autoreactive antibodies in nasal polyps

Els De SchryverLien CalusHenryk BonteNatalie De RuyckHannah GouldErin DonovanDirk ElewautRudolf ValentaIrene MittermannJan Gutermuth et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The response to nasal allergen provocation with grass pollen is reduced in patients with chronic rhinosinusitis with nasal polyposis and grass sensitization

LIEN CALUSLIEN DEVUYSTThibaut Van ZeleNatalie De RuyckLara DeryckeClaus BachertPhilippe Gevaert

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

2015

Local immunoglobulin E in the nasal mucosa : clinical implications

Els De SchryverLIEN DEVUYSTLara DeryckeMelissa DullaersThibaut Van ZeleClaus BachertPhilippe Gevaert

A1 Journal Article in ALLERGY ASTHMA & IMMUNOLOGY RESEARCH

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in chronic rhinosinusitis with nasal polyps

Yu ZhangLara DeryckeLuo ZhangGabriële HoltappelsXiangdong WangNan ZhangClaus Bachert

Three dimensional computed tomographic analysis of sinonasal air volume as an objective outcome measure for chronic rhinosinusitis with nasal polyps

B PauwelsF FerreiraW VosC Van HolsbekeJ De BackerLara DeryckeClaus Bachert

2014

Mixed T helper cell signatures in chronic rhinosinusitis with and without polyps

Lara DeryckeStefanie EyerichKoen Van CrombruggenClaudina Perez NovoGabriële HoltappelsNatalie De RuyckPhilippe GevaertClaus Bachert

A1 Journal Article in PLOS ONE

The expression of dendritic cell subsets in severe chronic rhinosinusitis with nasal polyps is altered

Rogerio PezatoClaudina Perez NovoGabriële HoltappelsNatalie De RuyckKoen Van CrombruggenGeert De VosClaus BachertLara Derycke

A1 Journal Article in IMMUNOBIOLOGY

The HMI™ module: a new tool to study the host-microbiota interaction in the human gastrointestinal tract in vitro

Massimo MarzoratiBarbara VanhoeckeTine De RyckMehdi Sadaghian SadabadIris PinheiroSam PossemiersPieter Van den AbbeeleLara DeryckeMarc BrackeJan Pieters et al.

A1 Journal Article in BMC MICROBIOLOGY

2013

Forkhead box P3 in human airway regulatory T cells is regulated by suppressor of cytokine signaling

F LanNan ZhangJ ZhangOlga KryskoQ ZhangJ XianLara DeryckeY QiK LiS Liu et al.

Forkhead box protein 3 in human nasal polyp regulatory T cells is regulated by the protein suppressor of cytokine signaling 3

Feng LanNan ZhangJie ZhangOlga KryskoQuanbo ZhangJunming XianLara DeryckeYanyu QiKai LiShixi Liu et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

2012

IL-17A as a regulator of neutrophil survival in nasal polyp disease of patients with and without cystic fibrosis

Lara DeryckeNan ZhangGabriële HoltappelsTINEKE DUTREClaus Bachert

A1 Journal Article in JOURNAL OF CYSTIC FIBROSIS

Local inflammation in chronic upper airway disease

LIEN CALUSThibaut Van ZeleLara DeryckeOlga KryskoTINEKE DUTREPeter TomassenMelissa DullaersClaus BachertPhilippe Gevaert

A1 Journal Article in CURRENT PHARMACEUTICAL DESIGN

N-Cadherin in neuroblastoma disease : expression and clinical significance

Tim LammensKatrien SwertsLara DeryckeANNEMIE DE CRAEMERSara De BrouwerKatleen De PreterNadine Van RoyJo VandesompeleFranki SpelemanJan Philippé et al.

A1 Journal Article in PLOS ONE

Persistent subretinal fluid after surgery for rhegmatogenous retinal detachment: hypothesis and review

Marc VeckeneerLara DeryckeEW LindstedtJ van MeursMaria CornelissenMarc BrackeElisabeth Van Aken

A1 Journal Article in GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

RAGE processing in chronic airway conditions: involvement of Staphylococcus aureus and ECP

Koen Van CrombruggenGabriële HoltappelsNatalie De RuyckLara DeryckePeter TomassenClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Role of imbalance of eicosanoid pathways and staphylococcal superantigens in chronic rhinosinusitis

Rogerio PezatoMonika Swierczyńska-KrępaEwa Niżankowska-MogilnickaLara DeryckeClaus BachertClaudina Perez Novo

A1 Journal Article in ALLERGY

2011

Alternatively activated macrophages and impaired phagocytosis of S-aureus in chronic rhinosinusitis

Olga KryskoGabriële HoltappelsNan ZhangMalgorzata KubicaKim DeswarteLara DeryckeSofie ClaeysHamida HammadGuy BrussellePeter Vandenabeele et al.

A1 Journal Article in ALLERGY

Capsaicin-induced vasodilatation in human nasal vasculature is mediated by modulation of cyclooxygenase-2 activity and abrogated by sulprostone

Koen Van CrombruggenLuc Van NassauwLara DeryckeJean-Piere TimmermansGabriële HoltappelsDavid HallClaus Bachert

A1 Journal Article in NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Production of monoclonal antibodies against hop-derived (Humulus lupulus L.) prenylflavonoids and the development of immunoassays

Ciska WynsLara DeryckeBram SoenenSelin BolcaDieter DeforceMarc BrackeArne Heyerick

A1 Journal Article in TALANTA

The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells

Lara DeryckeChristophe StoveAnne-Sophie Vercoutter-EdouartOlivier De WeverLaurent DolléNathalie ColpaertHerman DepypereJean-Claude MichalskiMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

2010

Different regulation of cigarette smoke induced inflammation in upper versus lower airways

Wouter HuvenneClaudina Perez NovoLara DeryckeNatalie De RuyckOlga KryskoTania MaesNele PauwelsLander RobaysKen BrackeGuy Joos et al.

A1 Journal Article in RESPIRATORY RESEARCH

Plasticity of the dendritic cells to activate T cells in chronic rhinosinusitis

Lara DeryckeClaus BachertGabriële Holtappels

A1 Journal Article in ALLERGY

Staphylococcus aureus and chronic airway disease

Lara DeryckeClaudina Perez NovoKoen Van CrombruggenMarie-Noëlle CorriveauClaus Bachert

A2 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

2009

Steroid effects on ZAP-70 and SYK in relation to apoptosis in poor prognosis chronic lymphocytic leukemia

Jerina BoelensSofie LustFEMKE VAN BOCKSTAELEMireille Van GeleAnn JanssensLara DeryckeBarbara VanhoeckeJan PhilippéMarc BrackeFritz Offner

A1 Journal Article in LEUKEMIA RESEARCH

TGF-beta signaling and collagen deposition in chronic rhinosinusitis

NICHOLAS VAN BRUAENELara DeryckeClaudina Perez NovoPhilippe GevaertGabriële HoltappelsNatalie De RuyckClaude CuvelierPaul Van CauwenbergeClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transthyretin levels in the vitreous correlate with change in visual acuity after vitrectomy

Elisabeth Van AkenEls De LetterM VeckeneerLara DeryckeT van EnschotI GeersS DelangheJoris Delanghe

A1 Journal Article in BRITISH JOURNAL OF OPHTHALMOLOGY

2008

Differential impact of TGF-β and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion

Hannelore DenysLara DeryckeAn HendrixWendy WestbroekAlexander GheldofKishan NarinePatrick PauwelsChristian GespachMarc BrackeOlivier De Wever

A1 Journal Article in CANCER LETTERS

Persistent foveal blebls: are they related to the Schwartz-Matsuo syndrome?

Marc VeckeneerElisabeth Van AkenMaria CornelissenLara Derycke

Plant polyphenolics as anti-invasive cancer agents

Marc BrackeBarbara VanhoeckeLara DeryckeSelin BolcaSam PossemiersArne HeyerickChristian StevensDenis De KeukeleireHerman DepypereWilly Verstraete et al.

A1 Journal Article in ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY

The microbial PhIP metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3 ',2 ': 4,5]imidazo[1,2-a]pyrimidin-5-ium chloride (PhIP-M1) induces DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells

Lynn VanhaeckeLara DeryckeF LE CURIEUXSofie LustD MARZINWilly VerstraeteMarc Bracke

A1 Journal Article in TOXICOLOGY LETTERS

2007

Cell motility and breast cancer metastasis.

Marc BrackeDaan De MaeseneerVeerle Van MarckLara DeryckeBarbara VanhoeckeOlivier De WeverHerman Depypere

Bookchapter in Metastasis of Breast Cancer.

Intestinal bacteria play a crucial role in the carcinogenic risk from 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

Lynn VanhaeckeMG KNIZELara DeryckeF LE CURIEUXmarc brackeWilly Verstraete

Soluble cadherins as cancer biomarkers

Olivier De WeverLara DeryckeAn HendrixGert De MeerleerF GODEAUHerman Depyperemarc bracke

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

2006

Non-enzymatic pharmacologic vitreolysis by beta-aminopropionitrile (BAPN)

Elisabeth Van AkenLara DeryckeHalima CharifTheo Luider

Soluble N-cadherin fragment promotes angiogenesis

Lara DeryckeL MORBIDELLIM ZICHEOlivier De Wevermarc brackeElisabeth Van Aken

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

Soluble N-cadherin in human biological fluids

Lara DeryckeOlivier De WeverVeronique StoveBarbara VanhoeckeJoris DelangheHerman Depyperemarc bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

The extracellular fragment of N-cahderin stimulates angiogenesis and migration and invasion of cells

Lara DeryckeElisabeth Van AkenMarc Bracke

The N-cadherin ectodomain: fate and finction outside the cancer cell

Lara DeryckeM Bracke

2005

Antiinvasive effect of xanthohumol, a prenylated chalcone present in hops (Humulus lupulus L.) and beer

Barbara VanhoeckeLara DeryckeV VAN MARCKHerman DepypereDenis De Keukeleiremarc bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Molecular targets of growth, differentiation, tissue integrity, and ectopic cell death in cancer cells

Lara DeryckeVeerle Van MarckHerman Depyperemarc bracke

A1 Journal Article in CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

2004

N-cadherin in the spotlight of cell-cell adhesion, differentiation, embryogenesis, invasion and signalling

Lara Deryckemarc bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

P-cadherin is up-regulated by the antiestrogen ICI 182,780 and promotes invasion of human breast cancer cells

Joana ParedesChristophe StoveVeronique StoveFernanda MilaneziVeerle Van MarckLara DeryckeMarcus MareelMarc BrackeFernando Schmitt

A1 Journal Article in CANCER RESEARCH

Soluble N-cadherin fragments: a new indicator of invasion. Vol. 59(2)

Lara DeryckeChristophe StoveMarieke GoossensVeerle Van MarckMarc Bracke

2003

New monoclonal antibodies for human N-cadherin.

Lara DeryckeChristophe StoveMarcus MareelMarc Bracke

Plasmin produces proangiogenic fragments

Elisabeth Van AkenMorbidelli LucaLara DeryckeZiche Marina

The heregulin/human epidermal growth factor receptor as a new growth factor system in melanoma with multiple ways of deregulation

Christophe StoveVeronique StoveLara DeryckeVeerle Van MarckMarcus Mareelmarc bracke

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

2001

An anti-invasive factor in the conditioned medium of a melanoma cell line: signaling via the ErbB receptors?

Christophe StoveTom BoterbergLara DeryckeD VANDEKERKHOVEMarcus MareelMarc Bracke