Research Explorer

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Researcher

Koen Breyne

Awards & Distinctions

30 Results

2023

Priming of the murine mammary gland with Staphylococcus chromogenes IM reduces bacterial growth of Streptococcus uberis : a proof-of-concept study

Niels Vander ElstJulie BellemansJonas SteenbruggeChloë GeeromsKoen BreyneSofie PiepersBruno Toledo SilvaFernando Nogueira De SouzaFreddy HaesebrouckSarne De Vliegher et al.

A1 Journal Article in VETERINARY RESEARCH

2020

Enterobactin deficiency in a coliform mastitis isolate decreases its fitness in a murine model : a preliminary host-pathogen interaction study

Niels Vander ElstKoen BreyneJonas SteenbruggeAmanda Jane GibsonDavid George Emslie SmithPierre GermonDirk WerlingEvelyne Meyer

A1 Journal Article in FRONTIERS IN VETERINARY SCIENCE

2018

Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer

Jonas SteenbruggeKoen BreyneKristel DemeyereOlivier De WeverNiek SandersWim Van Den BroeckCecile ColpaertPeter VermeulenSteven Van LaereEvelyne Meyer

A1 Journal Article in JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Immunomodulation of host chitinase 3-like 1 during a mammary pathogenic Escherichia coli infection

Koen BreyneJonas SteenbruggeKristel DemeyereChun Geun LeeJack A EliasWolfram PetzlDavid GE SmithPierre GermonEvelyne Meyer

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Staphylococcus aureus extracellular vesicles elicit an immunostimulatory response in vivo on the murine mammary gland

Natayme R. TartagliaKoen BreyneEvelyne MeyerChantal CautyJulien JardinDenis ChretienAurelien DupontKristel DemeyereNadia BerkovaVasco Azevedo et al.

A1 Journal Article in FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

2017

Efficacy and safety of a bovine-associated Staphylococcus aureus phage cocktail in a murine model of mastitis

Koen BreyneRyan W HonakerZachary HobbsManuela RichterMaciej ZaczekTaylor SpanglerJonas SteenbruggeRebecca LuAnika KinkhabwalaBruno Marchon et al.

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Preconditioning with lipopolysaccharide or lipoteichoic acid protects against Staphylococcus aureus mammary infection in mice

Koen BreyneJonas SteenbruggeKristel DemeyereTom Vanden BergheEvelyne Meyer

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

The crosstalk between macrophages and 4T1 mammary tumor cells promotes metastasis in a novel intraductal model for breast cancer

Jonas SteenbruggeKoen BreyneLore Vander PlanckenKristel DemeyereNiek SandersCecile ColpaertSteven Van LaereEvelyne Meyer

2016

Chitinase 3-like 1 as breast cancer metastasis biomarker for differential tumor progression in the intraductal versus the fat pad preclinical model

Jonas SteenbruggeKoen BreyneSofie DeniesMelissa DekimpeKristel DemeyereOlivier De WeverNiek SandersEvelyne Meyer

Comparison of the adipose and luminal mammary gland compartment as orthotopic inoculation sites in a 4T1-based immunocompetent preclinical model for triple-negative breast cancer

Jonas SteenbruggeKoen BreyneSofie DeniesMelissa DekimpeKristel DemeyereOlivier De WeverPeter VermeulenSteven Van LaereNiek SandersEvelyne Meyer

A1 Journal Article in JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Disruption of the sigS gene attenuates the local innate immune response to Staphylococcus aureus in a mouse mastitis model

Vincent PetonKoen BreyneLucie RaultKristel DemeyereNadia BerkovaEvelyne MeyerSergine EvenYves Le Loir

A1 Journal Article in VETERINARY MICROBIOLOGY

Don’t let the 'bad bugs' bite: hamamelitannin analogues as adjuvants for vancomycin in the treatment of MRSA biofilm infections

Arno VermoteGilles BrackmanMartijn RisseeuwKoen BreyneEvelyne MeyerP CosTom CoenyeSerge Van Calenbergh

Hamamelitannin analogues that modulate quorum sensing as potentiators of antibiotics against Staphylococcus aureus

Arno VermoteGilles BrackmanMartijn RisseeuwBieke VanhouttePaul CosKristof Van HeckeKoen BreyneEvelyne MeyerTom CoenyeSerge Van Calenbergh

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The quorum sensing inhibitor hamamelitannin increases antibiotic susceptibility of Staphylococcus aureus biofilms by affecting peptidoglycan biosynthesis and eDNA release

Gilles BrackmanKoen BreyneRiet De RyckeArno VermoteFilip Van NieuwerburghEvelyne MeyerSerge Van CalenberghTom Coenye

A1 Journal Article in SCIENTIFIC REPORTS

2015

A pilot study using a mouse mastitis model to study differences between bovine associated coagulase-negative staphylococci

Koen BreyneSarne De VliegherAnneleen De VisscherSofie PiepersEvelyne Meyer

A1 Journal Article in JOURNAL OF DAIRY SCIENCE

Inflammatory signaling in a mouse mastitis model using bovine-associated bacterial isolates : a basis for novel curative and preventive strategies?

Koen BreyneEvelyne Meyer

Is intraductal inoculation of tumour cells a more relevant in vivo model for immune-competent breast cancer metastasis than the classical fat pad model?

Koen BreyneSofie DeniesJonas SteenbruggeMelissa DekimpeKristel DemeyereOlivier De WeverNiek SandersEvelyne Meyer

2014

Adaptation of an intraductal mouse mastitis model to study the effect of inflammation in breast cancer metastasis

Koen BreyneSofie DeniesDieter DemonNiek SandersEvelyne Meyer

Infection of the lactating mammary gland: current status on the molecular biology of mastitis

Koen BreyneEvelyne Meyer

Bookchapter in Mammary glands : anatomy, development and diseases

Non-classical ProIL-1beta activation during mammary gland infection is pathogen-dependent but caspase-1 independent

Koen BreyneSteven CoolDieter DemonKristel DemeyereTom VandenberghePeter VandenabeeleHarald CarlsenWim Van Den BroeckNiek SandersEvelyne Meyer

Non-classical ProIL-1beta activation during mammary gland infection is pathogen-dependent but caspase-1 independent

Koen BreyneSteven CoolDieter DemonKristel DemeyereTom VandenberghePeter VandenabeeleHarald CarlsenWim Van Den BroeckNiek SandersEvelyne Meyer

A1 Journal Article in PLOS ONE

Optimalization and characterization of a novel intraductal mouse mammary tumor model

Koen BreyneSofie DeniesDieter DemonNiek SandersEvelyne Meyer

2013

Comparison of in vivo optical systems for bioluminescence and fluorescence imaging

Steven CoolKoen BreyneEvelyne MeyerStefaan De SmedtNiek Sanders

A1 Journal Article in JOURNAL OF FLUORESCENCE

Escherichia coli induces bovine neutrophil cell death independent from caspase-3/-7/-1, but with phosphatidylserine exposure prior to membrane rupture

Kristel DemeyereQuinten RemijsenDieter DemonKoen BreyneSofie NotebaertFilip BoyenChristopher J GuérinPeter VandenabeeleEvelyne Meyer

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Short communication: Antimicrobial efficacy of intramammary treatment with a novel biphenomycin compound against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli-induced mouse mastitis

Dieter DemonKoen BreyneGuido SchifferEvelyne Meyer

A1 Journal Article in JOURNAL OF DAIRY SCIENCE

2012

Flow cytometric immunophenotyping of the bacterially infected murine mammary gland

Koen BreyneKristel DemeyereDieter DemonHoward KendrickWim Van Den BroeckMatthew SmalleyEvelyne Meyer

The intramammary efficacy of first generation cephalosporins against Staphylococcus aureus mastitis in mice

Dieter DemonCarolin LudwigKoen BreyneDavid GuédéJulia-Charlotte DönerRobrecht FroymanEvelyne Meyer

A1 Journal Article in VETERINARY MICROBIOLOGY

2011

Immunophenotyping of mammary gland cells in an acute mouse mastitis model

Koen BreyneDieter DemonKristel DemeyereEvelyne Meyer

The in vivo role of executioner caspase-3 and -7 in the Escherichia coli-infected mammary gland

Koen BreyneDieter DemonTom Vanden BerghePeter VandenabeeleEvelyne Meyer

2010

Role of caspase-7 during early involution of the Escherichia coli- or the Staphylococcus aureus-infected mammary gland

Koen BreyneDieter DemonTom Vanden BerghePeter VandenabeeleEvelyne Meyer