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Researcher
Koen Beerens
Profile
Projects
Publications
Activities
40
Results
2022
Metabolism and health effects of rare sugars in a CACO-2/HepG2 coculture model
Amar Daniël Emanuel Van Laar
Charlotte Grootaert
Filip Van Nieuwerburgh
Dieter Deforce
Tom Desmet
Koen Beerens
John Van Camp
A1
Journal Article
in
NUTRIENTS
2022
Sweet biotechnology : enzymatic production and digestibility screening of novel kojibiose and nigerose analogues
Shari Dhaene
Amar Daniël Emanuel Van Laar
Marc De Doncker
Emma De Beul
Koen Beerens
Charlotte Grootaert
Jurgen Caroen
Johan Van der Eycken
John Van Camp
Tom Desmet
A1
Journal Article
in
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
2022
2021
Defined synthesis of cellotriose by cellobiose phosphorylase mutant
Zorica Ubiparip
David Sáez
Koen Beerens
Tom Desmet
C3
Conference
2021
Discovery of a novel GDP-glucose 4-epimerase in archaea reveals an uncommon promiscuity
Carlos Alvarez Quispe
Matthieu Da Costa
Koen Beerens
Tom Desmet
C3
Conference
2021
Engineering of a thermostable biocatalyst for the synthesis of 2-O-glucosylglycerol
Jorick Franceus
Zorica Ubiparip
Koen Beerens
Tom Desmet
A1
Journal Article
in
CHEMBIOCHEM
2021
Engineering of cellobiose phosphorylase for the synthesis of prebiotic cellotriose
Zorica Ubiparip
David Sáez Moreno
Koen Beerens
Tom Desmet
C3
Conference
2021
Expanding the enzyme repertoire for sugar nucleotide epimerization : the CDP-tyvelose 2-epimerase from Thermodesulfatator atlanticus for glucose/mannose interconversion
Christian Rapp
Stevie Van Overtveldt
Koen Beerens
Hansjörg Weber
Tom Desmet
Bernd Nidetzky
A1
Journal Article
in
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
2021
Exploration of GH94 sequence space for enzyme discovery reveals a novel glucosylgalactose phosphorylase specificity
Marc De Doncker
Chloé De Graeve
Jorick Franceus
Koen Beerens
Vladimír Křen
Helena Pelantová
Ronny Vercauteren
Tom Desmet
A1
Journal Article
in
CHEMBIOCHEM
2021
Kojibiose and trehalose long-term supplementation reveals significant metabolic differences and disaccharide dependent microbial community shift in a human gastrointestinal model
Stanley Omondi Onyango
Koen Beerens
Xinlin Jiao
Tom Desmet
Tom Van de Wiele
C3
Conference
2021
Stereo-electronic control of reaction selectivity in short-chain dehydrogenases : decarboxylation, epimerization, and dehydration
Annika J.E. Borg
Koen Beerens
Martin Pfeiffer
Tom Desmet
Bernd Nidetzky
A1
Journal Article
in
CURRENT OPINION IN CHEMICAL BIOLOGY
2021
Structure-function relationships in NDP-sugar active SDR enzymes : fingerprints for functional annotation and enzyme engineering
Koen Beerens
C3
Conference
2021
Structure-function relationships in NDP-sugar active SDR enzymes : fingerprints for functional annotation and enzyme engineering
Matthieu Da Costa
Ophelia Gevaert
Stevie Van Overtveldt
Joanna Lange
Henk-Jan Joosten
Tom Desmet
Koen Beerens
A1
Journal Article
in
BIOTECHNOLOGY ADVANCES
2021
Towards sustainable production of defined oligosaccharides : enzymatic synthesis of high purity cellotriose
Zorica Ubiparip
David Sáez Moreno
Koen Beerens
Tom Desmet
C3
Conference
2021
β-Glucan phosphorylases in carbohydrate synthesis
Zorica Ubiparip
Marc De Doncker
Koen Beerens
Jorick Franceus
Tom Desmet
A1
Journal Article
in
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
2021
2020
Determinants of the nucleotide specificity in the carbohydrate epimerase family 1
Stevie Van Overtveldt
Matthieu Da Costa
Ophelia Gevaert
Henk-Jan Joosten
Koen Beerens
Tom Desmet
A1
Journal Article
in
BIOTECHNOLOGY JOURNAL
2020
Engineering of cellobiose phosphorylase for the defined synthesis of cellotriose
Zorica Ubiparip
David Sáez Moreno
Koen Beerens
Tom Desmet
A1
Journal Article
in
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
2020
Fermentation of rare sugar kojibiose by the oral bacteria is slow yet bacteria specific
Stanley Omondi Onyango
Nele De Clercq
Koen Beerens
Tom Desmet
Tom Van de Wiele
C3
Conference
2020
GDP-altrose as novel product of GDP-mannose 3,5-epimerase : revisiting its reaction mechanism
Ophelia Gevaert
Stevie Van Overtveldt
Matthieu Da Costa
Koen Beerens
Tom Desmet
A1
Journal Article
in
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
2020
Novel insights into the existence of the putative UDP-glucuronate 5-epimerase specificity
Ophelia Gevaert
Stevie Van Overtveldt
Matthieu Da Costa
Koen Beerens
Tom Desmet
A1
Journal Article
in
CATALYSTS
2020
Oral microbiota display profound differential metabolic kinetics and community shifts upon incubation with sucrose, trehalose, kojibiose, and xylitol
Stanley Omondi Onyango
Nele De Clercq
Koen Beerens
John Van Camp
Tom Desmet
Tom Van de Wiele
A1
Journal Article
in
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
2020
Synthesis, trehalase hydrolytic resistance and inhibition properties of 4-and 6-substituted trehalose derivatives
Shari Dhaene
Johan Van der Eycken
Koen Beerens
Jorick Franceus
Tom Desmet
Jurgen Caroen
A1
Journal Article
in
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2020
2019
Characterization of the first bacterial and thermostable GDP-mannose 3,5-epimerase
Ophelia Gevaert
Stevie Van Overtveldt
Koen Beerens
Tom Desmet
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2019
Discovery of novel cellodextrin phosphorylases : where bioinformatics meets biochemistry
Zorica Ubiparip
Jorick Franceus
Nídia Martins
Koen Beerens
Tom Desmet
C3
Conference
2019
Rational design of an improved transglucosylase for production of the rare sugar nigerose
Jorick Franceus
Shari Dhaene
Hannes Decadt
Judith Vandepitte
Jurgen Caroen
Johan Van der Eycken
Koen Beerens
Tom Desmet
A1
Journal Article
in
CHEMICAL COMMUNICATIONS
2019
2018
Converting galactose into the rare sugar talose with cellobiose 2-epimerase as biocatalyst
Stevie Van Overtveldt
Ophelia Gevaert
Martijn Cherlet
Koen Beerens
Tom Desmet
A1
Journal Article
in
MOLECULES
2018
Evolutionary analysis as a powerful complement to energy calculations for protein stabilization
Koen Beerens
Stanislav Mazurenko
Antonin Kunka
Sergio M. Marques
Niels Hansen
Milos Musil
Radka Chaloupkova
Jitka Waterman
Jan Brezovsky
David Bednar
Zbynek Prokop
Jiri Damborsky
A1
Journal Article
in
ACS CATALYSIS
2018
Molecular gating of an engineered enzyme captured in real time
Piia Kokkonen
Jan Sykora
Zbynek Prokop
Avisek Ghose
David Bednar
Mariana Amaro
Koen Beerens
Sarka Bidmanova
Michaela Slanska
Jan Brezovsky
Jiri Damborsky
Martin Hof
A1
Journal Article
in
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2018
Thermostable alpha-glucan phosphorylases : characteristics and industrial applications
Zorica Ubiparip
Koen Beerens
Jorick Franceus
Ronny Vercauteren
Tom Desmet
A1
Journal Article
in
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
2018
2017
Biocatalytic synthesis of the rare sugar kojibiose : process scale-up and application testing
Koen Beerens
Karel De Winter
Davy Van de Walle
Charlotte Grootaert
Senem Kamiloglu
Lisa Miclotte
Tom Van de Wiele
John Van Camp
Koen Dewettinck
Tom Desmet
A1
Journal Article
in
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
2017
Disulfide bridges as essential elements for the thermostability of lytic polysaccharide monooxygenase LPMO10C from Streptomyces coelicolor
Magali Tanghe
Barbara Danneels
Matthias Last
Koen Beerens
Ingeborg Stals
Tom Desmet
A1
Journal Article
in
PROTEIN ENGINEERING DESIGN & SELECTION
2017
Exploration of protein unfolding by modelling calorimetry data from reheating
Stanislav Mazurenko
Antonin Kunka
Koen Beerens
Christopher M. Johnson
Jiri Damborsky
Zbynek Prokop
A1
Journal Article
in
SCIENTIFIC REPORTS
2017
The 'epimerring' highlights the potential of carbohydrate epimerases for rare sugar production
Koen Beerens
Stevie Van Overtveldt
Tom Desmet
A1
Journal Article
in
BIOCATALYSIS AND BIOTRANSFORMATION
2017
2016
Stability analysis of a plant glycosyltransferase
Griet Dewitte
Koen Beerens
Margo Diricks
Tom Desmet
C3
Conference
2016
2015
A structural classification of carbohydrate epimerases : from mechanistic insights to practical applications
Stevie Van Overtveldt
Tom Verhaeghe
Henk-Jan Joosten
Tom van den Bergh
Koen Beerens
Tom Desmet
A1
Journal Article
in
BIOTECHNOLOGY ADVANCES
2015
FireProt : energy- and evolution-based computational design of thermostable multiple-point mutants
David Bednar
Koen Beerens
Eva Sebestova
Jaroslav Bendl
Sagar Khare
Radka Chaloupkova
Zbynek Prokop
Jan Brezovsky
David Baker
Jiri Damborsky
A1
Journal Article
in
PLOS COMPUTATIONAL BIOLOGY
2015
Site-specific analysis of protein hydration based on unnatural amino acid fluorescence
Mariana Amaro
Jan Brezovský
Silvia Kováčová
Jan Sýkora
David Bednář
Václav Němec
Veronika Lišková
Nagendra Prasad Kurumbang
Koen Beerens
Radka Chaloupková
Kamil Paruch
Martin Hof
Jiří Damborský
A1
Journal Article
in
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2015
UDP-hexose 4-epimerases: a view on structure, mechanism and substrate specificity
Koen Beerens
Wim Soetaert
Tom Desmet
A1
Journal Article
in
CARBOHYDRATE RESEARCH
2015
2013
Characterization and engineering of epimerases for the production of rare sugars
Koen Beerens
Wim Soetaert
Tom Desmet
Dissertation
2013
Characterization and mutational analysis of the UDP-Glc(NAc) 4-epimerase from Marinithermus hydrothermalis
Koen Beerens
Wim Soetaert
Tom Desmet
A1
Journal Article
in
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
2013
2012
Enzymes for the biocatalytic production of rare sugars
Koen Beerens
Tom Desmet
Wim Soetaert
A1
Journal Article
in
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
2012
