Research Explorer

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Researcher

Kodi Ravichandran

Publications & Research Data

Awards & Distinctions

46 Results

2025

Apoptotic cells are not all created equal

Amanda O. WongKodi Ravichandran

Editorial material

CORESH : a gene signature-based search engine for public gene expression datasets

Vladimir SukhovAigul NugmanovaYury VorontsovParul MehrotraMaksim KleverovKodi RavichandranMaxim ArtyomovAlexey Sergushichev

A1 Journal Article in NUCLEIC ACIDS RESEARCH

For better or worse : the impact of necrotic cell death modalities

Peter VandenabeeleMarcus ConradAdam Wahida

Bookchapter in Apoptosis and other forms of cell death in the regulation of inflammation in health and disease

Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair

Federico Francesco De PontiAnna BujkoZhuangzhuang LiuPaul CollinsSara SchuermansChristian MaueröderSeraja AmstelveenTinne ThonéLiesbet MartensJohn McKendrick et al.

A1 Journal Article in IMMUNITY

2024

CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+T cells in diabetic autoimmunity

Neetu SrivastavaHao HuOrion J. PetersonAnthony N. VomundMarta StremskaMohammad ZamanShilpi GiriTiandao LiCheryl F. LichtiPavel N. Zakharov et al.

A1 Journal Article in IMMUNITY

Metabolite-based inter-kingdom communication controls intestinal tissue recovery following chemotherapeutic injury

Christopher AndersonLaura BoeckaertsPriscilla ChinJavier BurgoaWei XieAmanda GonçalvesGillian BlanckeSam BensonSebastian RogattiMariska S. Simpson et al.

A1 Journal Article in CELL HOST & MICROBE

No need to 'sugar coat' : removing glycocalyx on apoptotic blebs promotes phagocytosis

Shannon M. KelleyKodi Ravichandran

Editorial material

Oxylipins and metabolites from pyroptotic cells act as promoters of tissue repair

Parul MehrotraSophia MaschalidiLaura BoeckaertsChristian MaueröderRochelle TixeiraJonathan PinneyJavier BurgoaVladimir SukhovYunus IncikChristopher Anderson et al.

A1 Journal Article in NATURE

Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release

Turan TufanGamze ComertpayAmbra VillaniGeoffrey M. NelsonMarina TerekhovaShannon KelleyPavel ZakharovRochelle M. EllisonOleg ShpynovMichael Raymond et al.

A1 Journal Article in NATURE

Targeting efferocytosis in inflammaging

Ivan K. H. PoonKodi Ravichandran

A1 Journal Article in ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY

TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice

Mario Ruiz PérezChristian MaueröderWolf SteelsBruno VerstraetenSahine LameireWei XieLaura WyckaertJelle HuysentruytTatyana DivertRia Roelandt et al.

A1 Journal Article in CELLULAR & MOLECULAR IMMUNOLOGY

2023

Autophagy critically controls skin inflammation and apoptosis-induced stem cell activation

Lisette Van HoveAnnagiada TonioloMohammad GhiaslooKim LecomteFleur BooneMaarten CiersKris RaaijmakersNiels VandammeJana RoelsSophia Maschalidi et al.

A1 Journal Article in AUTOPHAGY

Defining solute carrier transporter signatures of murine immune cell subsets

Tania Love AaesJavier BurgoaKodi Ravichandran

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

LXR signaling controls homeostatic dendritic cell maturation

Victor BosteelsSandra MaréchalClint De NolfSofie RennenJonathan MaelfaitSimon TavernierJessica VettersEvelien Van De VeldeFarzaneh FayazpourKim Deswarte et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection

Lien VerboomChristopher AndersonMaude JansIoanna PettaGillian BlanckeArne MartensMozes SzeTino HochepiedKodi RavichandranLars Vereecke et al.

A1 Journal Article in CELL DEATH & DISEASE

Phagocytic clearance of dying cells and its implications

Kodi Ravichandran

Editorial material

Phagocytosis in the retina promotes local insulin production in the eye

J. Iker EtchegarayShannon KelleyKristen PenberthyLaura KarvelyteYosuke NagasakaSofia GasperinoSoumen PaulVikram SeshadriMichael RaymondAna Royo Marco et al.

A1 Journal Article in NATURE METABOLISM

2022

Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration

Viviane TranSarah NahleAmelie RobertInes DesanlisRyan KilloranSophie EhresmannMarie-Pier ThibaultDavid BarfordKodi RavichandranMartin Sauvageau et al.

A1 Journal Article in NATURE COMMUNICATIONS

Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity

Bartosz WiernickiSophia MaschalidiJonathan PinneySandy Adjemian CataniTom Vanden BergheKodi RavichandranPeter Vandenabeele

A1 Journal Article in NATURE COMMUNICATIONS

Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation

Sho MoriokaDaiki KajiokaYusuke YamaokaRochelle M. EllisonTuran TufanInge L. WerkmanShinji TanakaBrady BarronSatoshi T. ItoSarah Kucenas et al.

A1 Journal Article in CELL

Clearing your mind : mechanisms of debris clearance after cell death during neural development

Kendra E. LiuMichael H. RaymondKodi RavichandranSarah Kucenas

A1 Journal Article in ANNUAL REVIEW OF NEUROSCIENCE

Drugging the efferocytosis process : concepts and opportunities

Parul MehrotraKodi Ravichandran

A1 Journal Article in NATURE REVIEWS DRUG DISCOVERY

Live cell tracking of macrophage efferocytosis during Drosophila embryo development in vivo

Michael H. RaymondAndrew J. DavidsonYi ShenDaniel R. TudorChristopher D. LucasSho MoriokaJustin S. A. PerryJulia KrapivkinaDavid PerraisLinus J. Schumacher et al.

A1 Journal Article in SCIENCE

Pannexin 1 drives efficient epithelial repair after tissue injury

Christopher D. LucasChristopher B. MedinaFinnius A. BrutonDavid A. DorwardMichael H. RaymondTuran TufanJ. Iker EtchegarayBrady BarronMagdalena E. M. OremekSanja Arandjelovic et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes

Sophia MaschalidiParul MehrotraBurcu Nur KeçeliHannah De CleeneKim LecomteRenée Van der CruyssenPauline JanssenJonathan PinneyGeert van LooDirk Elewaut et al.

A1 Journal Article in NATURE

2021

A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism

Leen CatrysseBastiaan MaesParul MehrotraArne MartensEsther HosteLiesbet MartensChristian MaueröderAnneleen RemmerieAnna BujkoKarolina Slowicka et al.

A1 Journal Article in CELL REPORTS

Efferocytosis by Paneth cells within the intestine

Laura S. ShankmanSamantha T. FleuryW. Britt EvansKristen K. PenberthySanja ArandjelovicRichard S. BlumbergHerve AgaisseKodi Ravichandran

A1 Journal Article in CURRENT BIOLOGY

ELMO1 signaling is a promoter of osteoclast function and bone loss

Sanja ArandjelovicJustin S. A. PerryMing ZhouAdam CeroiIgor SmirnovScott F. WalkLaura S. ShankmanIsabelle CambréSuna Onengut-GumuscuDirk Elewaut et al.

A1 Journal Article in NATURE COMMUNICATIONS

Microbes exploit death-induced nutrient release by gut epithelial cells

Christopher AndersonChristopher B. MedinaBrady J. BarronLaura KarvelyteTania Love AaesIrina LambertzJustin S. A. PerryParul MehrotraAmanda GonçalvesKelly Lemeire et al.

A1 Journal Article in NATURE

OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity

Esther HosteKim LecomteKarl AnnusverNiels VandammeJana RoelsSophia MaschalidiLien VerboomHanna-Kaisa VikkulaMozes SzeLisette Van Hove et al.

A1 Journal Article in NATURE COMMUNICATIONS

Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation

Christopher B. MedinaYu-Hsin ChiuMarta E. StremskaChristopher D. LucasIvan PoonKenneth S. TungMichael R. ElliottBimal DesaiUlrike M. LorenzDouglas A. Bayliss et al.

A1 Journal Article in IMMUNITY

Phagocytosis : sweet repulsions via the glycocalyx

Sophia MaschalidiKodi Ravichandran

Editorial material

Putting the brakes on phagocytosis : "don't-eat-me" signaling in physiology and disease

Shannon M. KelleyKodi Ravichandran

A1 Journal Article in EMBO REPORTS

The role of lipid peroxidation in cell death and adaptive immune system regulation

Bartosz WiernickiPeter VandenabeeleKodi RavichandranTom Vanden Berghe

2020

Astrocytic trans-differentiation completes a multicellular paracrine feedback loop required for medulloblastoma tumor growth

Maojin YaoP. Britten VenturaYing JiangFausto J. RodriguezLixin WangJustin S. A. PerryYibo YangKelsey WahlRowena B. CrittendenMariko L. Bennett et al.

A1 Journal Article in CELL

Metabolites released from apoptotic cells act as tissue messengers

Christopher B. MedinaParul MehrotraSanja ArandjelovicJustin S.A. PerryYizhan GuoSho MoriokaBrady BarronScott F. WalkBart GhesquiereUlrike Lorenz et al.

A1 Journal Article in NATURE

2019

A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis

Sanja ArandjelovicJustin SA PerryChristopher D. LucasKristen K PenberthyTae-Hyoun KimMing ZhouDorian A RosenTzu-Ying ChuangAlexandra M BettinaLaura S Shankman et al.

A1 Journal Article in NATURE IMMUNOLOGY

Epithelial HMGB1 delays skin wound healing and drives tumor initiation by priming neutrophils for NET formation

Esther HosteChristian MaueröderLisette Van HoveLeen CatrysseHanna-Kaisa VikkulaMozes SzeBastiaan MaesDyah KarjosukarsoLiesbet MartensAmanda Gonçalves et al.

A1 Journal Article in CELL REPORTS

Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway

Justin SA PerrySho MoriokaChristopher B MedinaJ Iker EtchegarayBrady BarronMichael H RaymondChristopher D LucasSuna Onengut-GumuscuEric DelpireKodi Ravichandran

A1 Journal Article in NATURE CELL BIOLOGY

Living on the edge : efferocytosis at the interface of homeostasis and pathology

Sho MoriokaChristian MaueröderKodi Ravichandran

A1 Journal Article in IMMUNITY

Phosphatidylserine on viable sperm and phagocytic machinery in oocytes regulate mammalian fertilization

Claudia M RivalWenhao XuLaura S ShankmanSho MoriokaSanja ArandjelovicChang Sup LeeKaren M WheelerRyan P SmithLisa B HaneyBrant E Isakson et al.

A1 Journal Article in NATURE COMMUNICATIONS

2018

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release

Sho MoriokaJustin SA PerryMichael H RaymondChristopher B MedinaYunlu ZhuLiyang ZhaoVlad SerbuleaSuna Onengut-GumuscuNorbert LeitingerSarah Kucenas et al.

A1 Journal Article in NATURE

Macrophages regulate the clearance of living cells by calreticulin

Dmitri KryskoKodi RavichandranPeter Vandenabeele

Editorial material

2017

Context-dependent compensation among phosphatidylserine-recognition receptors

Kristen K PenberthyClaudia RivalLaura S ShankmanMichael H RaymondJianye ZhangJustin SA PerryChang Sup LeeClaudia Z HanSuna Onengut-GumuscuKrzysztof Palczewski et al.

A1 Journal Article in SCIENTIFIC REPORTS

2016

Boosting apoptotic cell clearance by colonic epithelial cells attenuates inflammation in vivo

Chang Sup LeeKristen K PenberthyKaren M WheelerIgnacio J JuncadellaPeter VandenabeeleJeffrey J LysiakKodi Ravichandran

A1 Journal Article in IMMUNITY

2015

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

L GalluzziJM Bravo-San PedroI VitaleSA AaronsonJM AbramsD AdamES AlnemriL AltucciD AndrewsM Annicchiarico-Petruzzelli et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION