Research Explorer

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Researcher

Kiran Toti

Awards & Distinctions

11 Results

2014

Synthesis and biological evaluation of 4'-hydroxymethyl deleted, transposed and modified nucleosides

Kiran TotiSerge Van Calenbergh

Synthesis and evaluation of N⁶-substituted apioadenosines as potential adenosine A₃ receptor modulators

Kiran TotiSteven M MossSilvia PaolettaZhan-Guo GaoKenneth A JacobsonSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of an apionucleoside family and discovery of a prodrug with anti-HIV activity

Kiran TotiMarco DerudasDavy SinnaeveFreya Van den BroeckLia MargamuljanaJosé MartinsPiet HerdewijnJan BalzariniChristopher McGuiganSerge Van Calenbergh

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

2013

Synthesis and evaluation of 5'-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors

Kiran TotiFrederick VerbekeMartijn RisseeuwVladimir FrecerHélène Munier-LehmannSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

2012

5,5'-Bis-substituted 2'-deoxyuridines as possible M. tuberculosis thymidylate kinase inhibitors

Kiran TotiFrederick VerbekeMartijn RisseeuwHélène Munier-LehmannSerge Van Calenbergh

Synthesis and biological evaluation of apionucleosides and their protides

Kiran TotiMarco DerudasDavy SinnaeveJosé MartinsChristopher McGuiganJan BalzariniKenneth A JacobsonSerge Van Calenbergh

2011

Dideoxyapiose nucleosides revisited : syntheses and protide derivatives

Kiran TotiJan BalzariniSerge Van Calenbergh

Synthesis and antiviral evaluation of α-L-2'-deoxythreofuranosyl nucleosides

Kiran TotiMarco DerudasChristopher McGuiganJan BalzariniSerge Van Calenbergh

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2010

L-2-deoxythreose nucleosides: synthesis and screening against viral strains

Kiran TotiJan BalzariniSerge Van Calenbergh

Synthesis of L-2-deoxythreose nucleosides as potential antiviral agents

Kiran TotiSerge Van Calenbergh

2009

Synthesis of L-2-deoxythreose nucleosides as potential antiviral agents

Kiran TotiSerge Van Calenbergh