Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Researcher

Kim De Ruyck

Awards & Distinctions

44 Results

2022

Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score

[missing] Minh-Phuong Huynh-LeRoshan KarunamuniChun Chieh FanLui AsonaWesley K. ThompsonMaria Elena MartinezRosalind A. EelesZsofia Kote-JaraiKenneth R. MuirArtitaya Lophatananon et al.

A1 Journal Article in PROSTATE CANCER AND PROSTATIC DISEASES

Use of angiotensin converting enzyme inhibitors is associated with reduced risk of late bladder toxicity following radiotherapy for prostate cancer

Sarah L. KernsAshley Amidon MorlangSharon M. LeeDerick R. PetersonBrian MarplesHong ZhangKevin BylundDoug RosenzweigWilliam HallKim De Ruyck et al.

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

2021

A SARS-CoV-2 sequence submission tool for the European Nucleotide Archive

Miguel RoncoroniBert DroesbekeIgnacio EguinoaKim De RuyckFlora D'AnnaDilmurat YusufBjörn GrüningRolf BackofenFrederik Coppens

A1 Journal Article in BIOINFORMATICS

2019

Shared heritability and functional enrichment across six solid cancers

Xia JiangHilary K FinucaneFredrick R SchumacherStephanie L SchmitJonathan P TyrerYounghun HanKyriaki MichailidouCorina LesseurKaroline B KuchenbaeckerJoe Dennis et al.

A1 Journal Article in NATURE COMMUNICATIONS

2018

A new approach for modeling patient overall radiosensitivity and predicting multiple toxicity endpoints for breast cancer patients

Chamberlain MbahKim De RuyckSilke De SchrijverCharlotte De SutterKimberly SchiettecatteChristel MontenLeen PaelinckWilfried De NeveHubert ThierensCatharine West et al.

A1 Journal Article in ACTA ONCOLOGICA

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

Fredrick R. SchumacherAli Amin Al OlamaSonja I. BerndtSara BenllochMahbubl AhmedEdward J. SaundersTokhir DadaevDaniel LeongamornlertEzequiel AnokianClara Cieza-Borrella et al.

A1 Journal Article in NATURE GENETICS

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

Tokhir DadaevEdward J. SaundersPaul J. NewcombeEzequiel AnokianDaniel A. LeongamornlertMark N. BrookClara Cieza-BorrellaMartina MijuskovicSarah WakerellAli Amin Al Olama et al.

A1 Journal Article in NATURE COMMUNICATIONS

2016

Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients

Christian Nicolaj AndreassenBarry S RosensteinSarah L KernsHarry OstrerDirk De RuysscherJamie A CesarettiGillian C BarnettAlison M DunningLeila DorlingCatharine ML West et al.

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

2015

Focus on 16p13.3 Locus in colon cancer

Evi MampaeyAnnelies FieuwThalia Van LaethemLiesbeth FerdinandeKathleen ClaesWim CeelenYves Van NieuwenhovePiet PattynMarc De ManKim De Ruyck et al.

A1 Journal Article in PLOS ONE

2014

A let-7 microRNA polymorphism in the KRAS 3'-UTR is prognostic in oropharyngeal cancer

Kim De RuyckFréderic DuprezLiesbeth FerdinandeChamberlain MbahEmmanuel Rios-VelazquezFrank HoebersMarleen PraetPhilippe DeronKatrien BonteErnst-Jan Speel et al.

A1 Journal Article in CANCER EPIDEMIOLOGY

Factors modifying the risk for developing acute skin toxicity after whole-breast intensity modulated radiotherapy

Sofie De LangheThomas MulliezLiv VeldemanVincent RemouchampsAnnick van GrevelingMonique GilsoulELINE DE SCHEPPERKim De RuyckWilfried De NeveHubert Thierens

A1 Journal Article in BMC CANCER

Integrated models for the prediction of late genitourinary complaints after high-dose intensity modulated radiotherapy for prostate cancer: making informed decisions

Sofie De LangheGert De MeerleerKim De RuyckPiet OstValérie FonteyneWilfried De NeveHubert Thierens

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Radiogenomics: radiobiology enters the era of big data and team science

Barry S RosensteinCatherine M WestSøren M BentzenJan AlsnerChristian Nicolaj AndreassenDavid AzriaGillian C BarnettMichael BaumannNeil BurnetJenny Chang-Claude et al.

Editorial material

Study of genomic alterations in colon carcinoma by array comparative genomic hybridization

Evi MampaeyAnnelies FieuwThalia Van LaethemNadine Van RoyLiesbeth FerdinandeWim CeelenPiet PattynYves Van NieuwenhoveKim De RuyckKaren Geboes et al.

2013

A predictive model for dysphagia following IMRT for head and neck cancer: introduction of the EMLasso technique

Kim De RuyckFréderic DuprezJoke WerbrouckNick SabbeSofie De LangheTom BoterbergIndira MadaniOlivier ThasWilfried De NeveHubert Thierens

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Acute radiation-induced nocturia in prostate cancer patients is associated with pretreatment symptoms, radical prostatectomy, and genetic markers in the TGFβ1 gene

Sofie De LangheKim De RuyckPiet OstValérie FonteyneJoke WerbrouckGert De MeerleerWilfried De NeveHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Characterisation of genome-wide copy number aberrations in colon cancer

Evi MampaeyNadine Van RoyKim De RuyckLiesbeth FerdinandeWim CeelenYves Van NieuwenhovePiet PattynKaren GeboesStéphanie Laurent

Predicting esophagitis after chemoradiation therapy for non-small cell lung cancer: an individual patient data meta-analysis

David A PalmaSuresh SenanCary OberijeJose BelderbosNúria Rodríguez de DiosJeffrey D BradleyR Bryan BarrigerMarta Moreno-JiménezTae Hyun KimSara Ramella et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Quantification of radiation-induced lung damage with CT scans: the possible benefit for radiogenomics

Dirk De RuysscherHoda SharifiGilles DefraeneSarah L KernsKim De RuyckStephanie PeetersJohan VansteenkisteRobert JerajFrank Van den HeuvelWouter Van Elmpt

2012

Epigenetic changes in lymphocytes of solvent-exposed individuals

Lode GodderisKarel De RaedtAli M TabishKatrien PoelsNathalie MaertensKim De RuyckSimon BulterysHubert ThierensMaria K Viaene

A1 Journal Article in EPIGENOMICS

No association between TGF-β1 polymorphisms and radiation-induced lung toxicity in a European cohort of lung cancer patients

An M VoetsCary OberijeRobin B StruijkBart ReymenKim De RuyckHubert ThierensKatrien VandecasteeleWilfried De NeveRuud HoubenDirk De Ruysscher et al.

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

2011

Development of a multicomponent prediction model for acute esophagitis in lung cancer patients receiving chemoradiotherapy

Kim De RuyckNick SabbeCary OberijeKatrien VandecasteeleOlivier ThasDirk De RuysscherPhillipe LambinJan Van MeerbeeckWilfried De NeveHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

2010

Association of TGFβ1 polymorphisms involved in radiation toxicity with TGFβ1 secretion in vitro

Kim De RuyckLaurence BeelsJan Van MeerbeeckWilfried De NeveHubert Thierens

A1 Journal Article in CYTOKINE

Establishment of a radiogenomics consortium

Catharine WestBarry S. RosensteinJan AlsnerDavid AzriaGillian BarnettAdrian BeggSoren BentzenNeil BurnetJenny Chang-ClaudeEric Chuang et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Genetic susceptibility in solvent induced neurobehavioral effects

Lode GodderisN MaertensVirginie de GelderA De LamperKim De RuyckM VernimmenS BulterysG MoensHubert ThierensMK Viaene

A1 Journal Article in NEUROTOXICITY RESEARCH

Genetic variation in three candidate genes and nicotine dependence, withdrawal and smoking cessation in hospitalized patients

Kim De RuyckKristiaan NackaertsLaurence BeelsJoke WerbrouckAnnick De VolderMarc MeysmanBihiyga SalhiJan Van MeerbeeckHubert Thierens

A1 Journal Article in PHARMACOGENOMICS

Prediction of late normal tissue complications in RT treated gynaecological cancer patients: potential of the γ-H2AX foci assay and association with chromosomal radiosensitivity

Joke WerbrouckKim De RuyckLaurence BeelsAnne VralMarc Van EijkerenWilfried De NeveHubert Thierens

A1 Journal Article in ONCOLOGY REPORTS

2009

A polymorphism in the promoter region of Ku70/XRCC6, associated with breast cancer risk and oestrogen exposure

Petra WillemsKim De RuyckRudy Van den BroeckeAmin MakarGianpaolo PerlettiHubert ThierensAnne Vral

A1 Journal Article in JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose and association with genetic polymorphisms in DNA DSB repair genes

Joke WerbrouckKim De RuyckFréderic DuprezLiv VeldemanKathleen ClaesMarc Van EijkerenTom BoterbergPetra WillemsAnne VralWilfried De Neve et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Association of TGFβ1 polymorphisms involved in radiation toxicity with TGFβ1 secretion in vitro

Kim De RuyckLaurence BeelsJan Van MeerbeeckWilfried De NeveHubert Thierens

2008

Chromosomal radiosensitivity in head and neck cancer patients: evidence for genetic predisposition?

Kim De RuyckVirginie de GelderMarc Van EijkerenTom BoterbergWilfried De NeveAnne VralHubert Thierens

A1 Journal Article in BRITISH JOURNAL OF CANCER

Polymorphisms in nonhomologous end-joining genes associated with breast cancer risk and chromosomal radiosensitivity

Petra WillemsKathleen ClaesAns BaeyensVeerle VandersickelJoke WerbrouckKim De RuyckBruce PoppeRudy Van den BroeckeAmin MakarEmanuela Marras et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Single-nucleotide polymorphisms in DNA double-strand break repair genes: Association with head and neck cancer and interaction with tobacco use and alcohol consumption

Joke WerbrouckKim De RuyckFréderic DuprezMarc Van EijkerenErnst RietzschelSofie BekaertAnne VralWilfried De NeveHubert Thierens

A1 Journal Article in MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

mBAND analysis of chromosome aberrations in lymphocytes exposed invitro to alpha-particles and gamma-rays

E JANETCA WHITEHOUSED HOLDSWORTHKim De RuyckKatia VandenbulckeHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

2007

Polymorphisms in base-excision repair and nucleotide-excision repair genes in relation to lung cancer risk

Kim De RuyckMarcin SzaumkesselIsabelle De RudderANNELORE DEHOORNEAnne VralKathleen ClaesAnja VelgheJan Van MeerbeeckHubert Thierens

A1 Journal Article in MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Predicting risk of radiation-induced lung injury

Indira MadaniKim De RuyckH GOEMINNEWilfried De NeveHubert ThierensJan Van Meerbeeck

A1 Journal Article in JOURNAL OF THORACIC ONCOLOGY

Radiogenomics in gynecological cancer patients

Kim De RuyckH Thierens

The characterization and transmissibility of chromosome aberrations induced in peripheral blood lymphocytes by in vitro alpha-particle radiation

EJ TAWNCA WHITEHOUSEKim De RuyckL HODGSONKatia VandenbulckeHubert Thierens

A1 Journal Article in RADIATION RESEARCH

2006

TGF beta 1 polymorphisms and late clinical radiosensitivity in patients treated for gynecologic tumors

Kim De RuyckMarc Van EijkerenKathleen ClaesKlaus BacherAnne VralWilfried De NeveHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

2005

Chromosomal radio sensitivity of breast cancer with a CHEK2 mutation

Ans BaeyensKathleen ClaesPetra WillemsKim De RuyckHubert ThierensAnne Vral

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

Cytogenetic biodosimetry of an accidental exposure of a radiological worker using multiple assays

Hubert ThierensKim De RuyckAnne VralVirginie de GelderCA WHITEHOUSEFJ TAWNI BOESMAN

A1 Journal Article in RADIATION PROTECTION DOSIMETRY

Microsatellite polymorphisms in DNA repair genes XRCC1, XRCC3 and XRCC5 in patients with gynecological tumors: Association with late clinical radiosensitivity and cancer incidence

Kim De RuyckCS WILDINGMarc Van EijkerenR MORTHIEREJ TAWNHubert Thierens

A1 Journal Article in RADIATION RESEARCH

Radiation-induced damage to normal tissues after radiotherapy in patients treated for gynecologic tumors: Association with single nucleotide polymorphisms in XRCC1, XRCC3, and OGG1 genes and in vitro chromosomal radiosensitivity in lymphocytes

Kim De RuyckMarc Van EijkerenKathleen ClaesR MORTHIERAnne De PaepeAnne VralLeo De RidderHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

2004

Biologic dosimetry of Re-188-HDD/lipiodol versus I-131-lipiodol therapy in patients with hepatocellular carcinoma

Kim De RuyckBieke LambertKlaus BacherF GEMMELFILIP DE VOSAnne VralLeo De RidderRudi DierckxHubert Thierens

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE