Research Explorer

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Researcher

Kevin Buyens

Awards & Distinctions

14 Results

2012

Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design

Kevin BuyensStefaan De SmedtKevin BraeckmansJo DemeesterLiesbeth PeetersLeo A van GrunsvenXavier de Mollerat du JeuRupa SawantVladimir TorchilinKatarina Farkasova et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2011

An in vitro assay based on surface plasmon resonance to predict the in vivo circulation kinetics of liposomes

BJ CrielaardA YousefiJP SchillemansC VermehrenKevin BuyensKevin BraeckmansTwan LammersG Storm

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Fluorescence single particle tracking for sizing of nanoparticles in undiluted biological fluids

Kevin BraeckmansKevin BuyensWim Bouquet-GeerardynChris VervaetPhilippe JoyeFilip De VosLaurent PlawinskiLoïc DoeuvreEduardo Angles-CanoNiek Sanders et al.

2010

Advanced fluorescence microscopy methods illuminate the transfection pathway of nucleic acid nanoparticles

Kevin BraeckmansKevin BuyensBroes NaeyeDries VercauterenHendrik DeschoutKoen RaemdonckKatrien RemautNiek SandersJo DemeesterStefaan De Smedt

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy

Kevin BuyensMartin MeyerErnst WagnerJo DemeesterStefaan De SmedtNiek Sanders

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Optimizing siRNA-nanocarriers for systemic delivery by monitoring their behavior in blood

Kevin BuyensStefaan De SmedtNiek Sanders

Sizing nanomatter in biological fluids by fluorescence single particle tracking

Kevin BraeckmansKevin BuyensWim Bouquet-GeerardynChris VervaetPhilippe JoyeFilip De VosLaurent PlawinskiLoic DoeuvreEduardo Angles-CanoNiek Sanders et al.

A1 Journal Article in NANO LETTERS

Synergistic effects between natural histone mixtures and polyethylenimine in non-viral gene delivery in vitro

Anne SchneeweissKevin BuyensMatthias GieseNiek SandersSebastian Ulbert

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

siRNA containing nanoparticles: stability of encapsulation and particle size

Kevin BuyensKevin BraeckmansJo DemeesterStefaan De SmedtNiek Sanders

2009

Biodegradable Dextran Nanogels for RNA Interference: Focusing on Endosomal Escape and Intracellular siRNA Delivery

Koen RaemdonckBroes NaeyeKevin BuyensRoosmarijn VandenbrouckeA HogsetJo DemeesterStefaan De Smedt

A1 Journal Article in Advanced Functional Materials

Elucidating the Encapsulation of Short Interfering RNA in PEGylated Cationic Liposomes

Kevin BuyensJo DemeesterStefaan De SmedtNiek Sanders

A1 Journal Article in Langmuir

Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging

OM MerkelD LibrizziA PfestroffT SchurratKevin BuyensNiek SandersStefaan De SmedtM BeheT Kissel

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Ultradeformable cationic liposomes for delivery of small interfering RNA (siRNA) into human primary melanocytes

Barbara GeusensJo LambertStefaan De SmedtKevin BuyensNiek SandersMireille Van Gele

A1 Journal Article in Journal of Controlled Release

2008

A fast and sensitive method for measuring the integrity of siRNA-carrier complexes in full human serum

Kevin BuyensBart LucasKoen RaemdonckKevin BraeckmansJ VERCAMMENJ HENDRIXY ENGELBORGHSStefaan De SmedtNiek Sanders

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE