Research Explorer

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Researcher

Kensaku Matsunami

Awards & Distinctions

21 Results

2025

Comparative analysis of tablet dissolution behavior : batch vs. continuous direct compression

Kensaku MatsunamiAlexander RyckaertHanne VerrecasAna Filipa Tavares da SilvaAndrew AndersonHåkan WikströmMelanie DumareyJames MannThomas De BeerValérie Vanhoorne et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Mathematical models of dissolution testing : challenges and opportunities toward real-time release testing

Kensaku MatsunamiAlexander RyckaertValérie VanhoorneAshish Kumar

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Mechanistic modelling in pharmaceutical product and process development : a review of distributed and discrete approaches

Kensaku MatsunamiPedro Martin SalvadorLuz Naranjo GómezGaia Sofia ComoliIsar CharmchiAshish Kumar

A2 Journal Article in CHEMICAL ENGINEERING RESEARCH & DESIGN

2024

Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation

Michiel PeetersAna Alejandra Barrera JiménezKensaku MatsunamiMichael GhijsEduardo dos Santos SchultzMina RoudgarTamas VighFanny StaufferIngmar NopensThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Hybrid modeling of T-shaped partial least squares regression and transfer learning for formulation and manufacturing process development of new drug products

Keita YaginumaKensaku MatsunamiLaure DescampsAlexander RyckaertThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Investigating screw-agitator speed ratio impact on feeding performance in pharmaceutical manufacturing using discrete element method

Luz Naranjo GómezKensaku MatsunamiPaul Van LiedekerkeThomas De BeerAshish Kumar

A1 Journal Article in SCIENTIFIC REPORTS

Scenario analysis of vaccine supply for COVID-19 in Japan using mathematical models of infectious diseases

Junu KimKensaku MatsunamiYusuke IchidaKozue OkamuraSara BadrHirokazu Sugiyama

A1 Journal Article in JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

2023

Development of concentration prediction models for personalized tablet manufacturing using near-infrared spectroscopy

Yusuke HayashiSaho OkazakiKensaku MatsunamiKazuya TanabeTakuya NagatoHirokazu Sugiyama

A1 Journal Article in CHEMICAL ENGINEERING RESEARCH & DESIGN

Evaluation of the influence of material properties and process parameters on granule porosity in twin-screw wet granulation

Michiel PeetersAna Alejandra Barrera JiménezKensaku MatsunamiFanny StaufferIngmar NopensThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Exploring the effect of raw material properties on continuous twin-screw wet granulation manufacturability

Michiel PeetersAna Alejandra Barrera JiménezKensaku MatsunamiDaan Van HauwermeirenFanny StaufferLærke ArnfastTamas VighIngmar NopensThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Linking material properties to 1D-PBM parameters towards a generic model for twin-screw wet granulation

Ana Alejandra Barrera JiménezKensaku MatsunamiDaan Van HauwermeirenMichiel PeetersFanny StaufferEduardo dos Santos SchultzAshish KumarThomas De BeerIngmar Nopens

A1 Journal Article in CHEMICAL ENGINEERING RESEARCH & DESIGN

Model development and calibration of two-dimensional population balance model for twin-screw wet granulation based on particle size distribution and porosity

Ana Alejandra Barrera JiménezKensaku MatsunamiMichael GhijsDaan Van HauwermeirenMichiel PeetersFanny StaufferThomas De BeerIngmar Nopens

A1 Journal Article in POWDER TECHNOLOGY

Partial least squares regression to calculate population balance model parameters from material properties in continuous twin-screw wet granulation

Ana Alejandra Barrera JiménezKensaku MatsunamiDaan Van HauwermeirenMichiel PeetersFanny StaufferEduardo dos Santos SchultzAshish KumarThomas De BeerIngmar Nopens

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes

Kensaku MatsunamiTomohiro MiuraKeita YaginumaShuichi TanabeSara BadrHirokazu Sugiyama

A1 Journal Article in COMPUTERS & CHEMICAL ENGINEERING

T-shaped partial least squares for high-dosed new active pharmaceutical ingredients in continuous twin-screw wet granulation : granule size prediction with limited material information

Kensaku MatsunamiJonathan MeyerMartin RowlandNeil DawsonThomas De BeerDaan Van Hauwermeiren

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Validation of model-based design of experiments for continuous wet granulation and drying

Kensaku MatsunamiTuur VandeputteAna Alejandra Barrera JiménezMichiel PeetersMichael GhijsDaan Van HauwermeirenFanny StaufferEduardo dos Santos SchultzIngmar NopensThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

2022

In-depth analysis of the impacts of material properties on size distributions in continuous twin-screw wet granulation to construct a generic 1D population balance model

Kensaku MatsunamiAna Alejandra Barrera JiménezMichiel PeetersDaan Van HauwermeirenThomas De BeerIngmar Nopens

Model-based design of experiments in drug product development in continuous manufacturing

Tuur VandeputteAna Alejandra Barrera JiménezKensaku MatsunamiMichiel PeetersMichael GhijsDaan Van HauwermeirenIngmar NopensThomas De Beer

Towards a generic population balance model for twin-screw wet granulation : from material properties to particle size distribution

Ana Alejandra Barrera JiménezDaan Van HauwermeirenKensaku MatsunamiMichiel PeetersThomas De BeerIngmar Nopens

Two-dimensional population balance model for twin-screw wet granulation : model development and calibration based on particle size distribution and porosity

Kensaku MatsunamiAna Alejandra Barrera JiménezMichiel PeetersMichael GhijsDaan Van HauwermeirenThomas De BeerIngmar Nopens

2021

Analysis of the effects of process parameters on start-up operation in continuous wet granulation

Kensaku MatsunamiAlexander RyckaertMichiel PeetersSara BadrHirokazu SugiyamaIngmar NopensThomas De Beer

A1 Journal Article in PROCESSES