Research Explorer

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Researcher

Ken Kersemans

Publications & Research Data

Awards & Distinctions

46 Results

2026

Investigating phloem transport dynamics in Arabidopsis through compartmental modelling of positron emission tomography data

Jens MinckeKaren J. KlothSarah VerbekeKen KersemansStefaan VandenbergheChristian VanhoveKathy Steppe

A1 Journal Article in PLANT METHODS

2025

Fractionated versus single-dose PSMA-targeted radioligand therapy as adjuvant therapy in a murine model for oral squamous cell carcinoma treated with immune checkpoint inhibitors

Michaël HenrotteDavid CreytensFilip De VosBenedicte DescampsLindsey DevisscherGabriële HoltappelsWouter HuvenneKen KersemansAmber MeskensSara Neyt et al.

Non-tumour-specific PSMA-targeted radionuclide therapy enhances immune checkpoint inhibition in a syngeneic oral cancer model

Michaël HenrotteDavid CreytensFilip De VosBenedicte DescampsLindsey DevisscherWouter HuvenneKen KersemansAmber MeskensChristian VanhoveJens Debacker

Prostate-specific membrane antigen-targeted radionuclide therapy as adjunct to Immune checkpoint Inhibition in an immunocompetent murine model for oral squamous cell carcinoma

Michaël HenrotteDavid CreytensFilip De VosBenedicte DescampsLindsey DevisscherWouter HuvenneKen KersemansSara NeytSylvie RotteyMichael Saerens et al.

2024

Prostate-specific membrane antigen as a potential theranostic target in a syngeneic immunocompetent murine model for oral squamous cell carcinoma

Michaël HenrotteDavid CreytensHilde De CockFilip De VosBenedicte DescampsLindsey DevisscherWouter HuvenneKen KersemansLieselotte MoermanChristian Vanhove et al.

Prostate-specific membrane antigen-targeted radionuclide therapy as a novel therapeutic approach in a syngeneic immunocompetent murine model for oral squamous cell carcinoma

Michaël HenrotteDavid CreytensFilip De VosBenedicte DescampsLindsey DevisscherWouter HuvenneKen KersemansSara NeytChristian VanhoveJens Debacker

2022

18F-PSMA-11 Versus 68Ga-PSMA-11 positron emission tomography/computed tomography for staging and biochemical recurrence of prostate cancer : a prospective double-blind randomised cross-over trial

Kathia De ManNick Van LaekenVanessa SchelfhoutWolfgang P. FendlerBieke LambertKen KersemansSarah PironNicolaas LumenKarel DecaesteckerValerie Fonteyne et al.

A1 Journal Article in EUROPEAN UROLOGY

Impact of 18F-PSMA-11 PET/CT on management of biochemical recurrence and high-risk prostate cancer staging 18F-PSMA-11 PET/CT and impact on prostate cancer management

Kathia De ManSarah PironNick Van LaekenLouke DelrueValerie FonteyneNicolaas LumenBliede Van den BroeckKen KersemansPiet OstVanessa Schelfhout

A1 Journal Article in MOLECULAR IMAGING AND BIOLOGY

Preclinical comparative study of [18F]AlF-PSMA-11 and [18F]PSMA-1007 in varying PSMA expressing tumors

Sarah PironJeroen VerhoevenJan CourtynKen KersemansBenedicte DescampsLeen PietersAnne VralChristian VanhoveFilip De Vos

A1 Journal Article in SCIENTIFIC REPORTS

2021

Impact of the molar activity and PSMA expression level on [18F]AlF-PSMA-11 uptake in prostate cancer

Sarah PironJeroen VerhoevenEmma De CosterBenedicte DescampsKen KersemansLeen PietersAnne VralChristian VanhoveFilip De Vos

A1 Journal Article in SCIENTIFIC REPORTS

2020

Intra-individual dynamic comparison of 18F-PSMA-11 and 68Ga-PSMA-11 in LNCaP xenograft bearing mice

Sarah PironJeroen VerhoevenBenedicte DescampsKen KersemansKathia De ManNick Van LaekenLeen PietersAnne VralChristian VanhoveFilip De Vos

A1 Journal Article in SCIENTIFIC REPORTS

Optimization of PET protocol and interrater reliability of 18F-PSMA-11 imaging of prostate cancer

Sarah PironKathia De ManVanessa SchelfhoutNick Van LaekenKen KersemansEric AchtenFilip De VosPiet Ost

A1 Journal Article in EJNMMI RESEARCH

2019

Biomimetic strategy towards gelatin coatings on PET : effect of protocol on coating stability and cell-interactive properties

Elena Diana GiolSandra Van VlierbergheRonald E UngerKen KersemansFilip De VosCharles James KirkpatrickPeter Dubruel

A1 Journal Article in JOURNAL OF MATERIALS CHEMISTRY B

New fluoroethyl phenylalanine analogues as potential LAT1-targeting PET tracers for glioblastoma

Jeroen VerhoevenFabian HulpiaKen KersemansJulie BolcaenStef De LombaerdeJan GoemanBenedicte DescampsGiorgio HallaertCaroline Van den BroeckeKarel Deblaere et al.

A1 Journal Article in SCIENTIFIC REPORTS

Radiation dosimetry and biodistribution of 18F-PSMA-11 for PET imaging of prostate cancer

Sarah PironKathia De ManNick Van LaekenYves D'AsselerKlaus BacherKen KersemansPiet OstKarel DecaesteckerPieter DeseyneValerie Fonteyne et al.

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Technical feasibility of [18F]FET and [18F]FAZA PET guided radiotherapy in a F98 glioblastoma rat model

Jeroen VerhoevenJulie BolcaenValerie De MeulenaereKen KersemansBenedicte DescampsSam DoncheCaroline Van den BroeckeTom BoterbergJean-Pierre Kalala OkitoKarel Deblaere et al.

A1 Journal Article in RADIATION ONCOLOGY

2018

[18F]-FET and [18F]-FAZA PET guided irradiation of glioblastoma in rats

Jeroen VerhoevenJulie BolcaenBenedicte DescampsTristan BaguetGiorgio HallaertKen KersemansTom BoterbergKarel DeblaereChristian VanhoveFilip De Vos et al.

Automated radiosynthesis of Al[18F]PSMA-11 for large scale routine use.

Ken KersemansKathia De ManJan CourtynTessa Van RoyenSarah PironLieselotte MoermanBoudewijn BransFilip De Vos

A1 Journal Article in APPLIED RADIATION AND ISOTOPES

Evaluating hepatobiliary transport with 18F labeled bile acids : the effect of radiolabel position and bile acid backbone on radiosynthesis, in vitro and in vivo performance

Stef De LombaerdeKen KersemansSara NeytJeroen VerhoevenChristian VanhoveFilip De Vos

Evaluating hepatobiliary transport with 18F-labeled bile acids : the effect of radiolabel position and bile acid structure on radiosynthesis and in vitro and in vivo performance

Stef De LombaerdeKen KersemansSara NeytJeroen VerhoevenChristian VanhoveFilip De Vos

A1 Journal Article in CONTRAST MEDIA & MOLECULAR IMAGING

Evaluation and preliminary radiation dosimetry of [18F]PSMA-11 for PET imaging of prostate cancer

Sarah PironKathia De ManNick Van LaekenYves D'AsselerKen KersemansPiet OstKarel DecaesteckerPieter DeseyneValerie FonteyneNicolaas Lumen et al.

Hypoxia imaging with 18F-FAZA PET/CT predicts radiotherapy response in esophageal adenocarcinoma xenografts

Elodie MelsensElly De VlieghereBenedicte DescampsChristian VanhoveKen KersemansFilip De VosIngeborg GoethalsBoudewijn BransOlivier De WeverWim Ceelen et al.

A1 Journal Article in RADIATION ONCOLOGY

The signature of the serotonin system in the chronic corticosterone depression mode : a study with (18F)MPPF, (18F)altaserin and (11C)DASB

Glenn PauwelynNick Van LaekenRobrecht DockxJeroen VerhoevenBenedicte DescampsKen KersemansKathelijne PeremansChris BaekenIngeborg GoethalsChristian Vanhove et al.

The signature of the serotonin system in the chronic corticosterone depression model : a study with [18F]MPPF, [18F]altanserin and [11C]DASB

Glenn PauwelynNick Van LaekenJeroen VerhoevenFilip De VosKathelijne PeremansRobrecht DockxChris BaekenBenedicte DescampsChristian VanhoveKen Kersemans et al.

A2 Journal Article in NEUROPSYCHIATRY

2017

In vitro and in vivo evaluation of the LAT1 PET tracer 2-[18F]FELP in comparison to [18F]FET and [18F]FDG

Jeroen VerhoevenJulie BolcaenKen KersemansValerie De MeulenaereBenedicte DescampsJean-Pierre Kalala OkitoCaroline Van den BroeckeKarel DeblaereChristian VanhoveIngeborg Goethals et al.

In vitro characterization of the amino acid PET tracer 2-[18F]FELP and in vivo comparison to [18F]FET and [18F]FDG in a F98 glioblastoma rat model

Jeroen VerhoevenTristan BaguetJulie BolcaenKen KersemansCaroline DumolynStef De LombaerdeJean-Pierre Kalala OkitoCaroline Van den BroeckeKarel DeblaereChristian Vanhove et al.

Synthesis, in vitro and in vivo evaluation of 3β-[18F]fluorocholic acid for the detection of drug-induced cholestasis in mice

Stef De LombaerdeSara NeytKen KersemansJeroen VerhoevenLindsey DevisscherHans Van VlierbergheChristian VanhoveFilip De Vos

A1 Journal Article in PLOS ONE

Synthesis, in vitro and in vivo evaluation of 3β-[18F]fluorocholic acid, a radiolabeled bile acid to detect drug-induced cholestasis in preclinical drug development

Stef De LombaerdeSara NeytKen KersemansJeroen VerhoevenLindsey DevisscherHans Van VlierbergheChristian VanhoveFilip De Vos

The effect of repeated corticosterone injections on the 5HT1a & 5HT2a receptor density and depression-like behaviour in male rats

Glenn PauwelynNick Van LaekenJeroen VerhoevenKen KersemansBenedicte DescampsChris BaekenChristian VanhoveFilip De Vos

2016

Evaluation of the LAT1 selective amino acid PET tracer 2-[18F]FELP in comparison to [18F]FET and [18F]FDG in a F98 glioblastoma rat model

Jeroen VerhoevenJulie BolcaenKen KersemansStef De LombaerdeBenedicte DescampsJean-Pierre Kalala OkitoCaroline Van den BroeckeKarel DeblaereChristian VanhoveIngeborg Goethals et al.

Gelatin- and starch-based hydrogels, part A : hydrogel development, characterization and coating

Ine Van NieuwenhoveAchim SalamonKirsten PetersGeert-Jan GraulusJosé MartinsDaniel FrankelKen KersemansFilip De VosSandra Van VlierberghePeter Dubruel

A1 Journal Article in CARBOHYDRATE POLYMERS

In vivo evaluation of blood based and reference tissue based PET quantifications of [11C]DASB in the canine brain

Nick Van LaekenOlivia TaylorIngeborgh PolisSara NeytKen KersemansAndre DobbeleirJimmy SaundersIngeborg GoethalsKathelijne PeremansFilip De Vos

A1 Journal Article in PLOS ONE

Synthesis, in vitro and in vivo small-animal SPECT evaluation of novel technetium labeled bile acid analogues to study (altered) hepatic transporter function

Sara NeytMaarten VliegenBjorn VerreetStef De LombaerdeKim BraeckmanChristian VanhoveMaarten Thomas HuismanCaroline DumolynKen KersemansFabian Hulpia et al.

A1 Journal Article in NUCLEAR MEDICINE AND BIOLOGY

The effect of repeated corticsterone injections on 5HT2a receptor density, cerebral glucose consumption and depression-like behaviour in rat brain : a pilot study

Glenn PauwelynNick Van LaekenMarlies VanthornoutKen KersemansBenedicte DescampsChris BaekenChristian VanhoveFilip De Vos

2015

Bio-inspired surface modification of PET for cardiovascular applications: case study of gelatin

Elena Diana GiolDavid SchaubroeckKen KersemansFilip De VosSandra Van VlierberghePeter Dubruel

A1 Journal Article in COLLOIDS AND SURFACES B-BIOINTERFACES

First step toward near-infrared continuous glucose monitoring: in vivo evaluation of antibody coupled biomaterials

Karolien GellynckValérie KodeckElke Van De WalleKen KersemansFilip De VosHeidi DeclercqPeter DubruelLieven VlaminckMaria Cornelissen

A1 Journal Article in EXPERIMENTAL BIOLOGY AND MEDICINE

2014

Evaluation of the PET-radioligand 11C DASB in dogs

Nick Van LaekenOlivia TaylorAndré DobbeleireIngeborgh PolisEva VandermeulenTim BosmansSara NeytKen KersemansIngeborg GoethalsKathelijne Peremans et al.

F-18 fluoromethylcholine (F-18 FCho) PET for the prediction of response according to the RANO criteria in glioblastoma patients

Julie BolcaenMarjan AcouTom BoterbergFilip De VosKen KersemansJean-Pierre Kalala OkitoGiorgio HallaertJacques CaemaertCaroline Van den BroeckeRoel Van Holen et al.

2013

Improved HPLC purification strategy for [11C]raclopride and [11C]DASB leading to high radiochemical yields and more practical high quality radiopharmaceutical formulations

Nick Van LaekenKen KersemansDieter De MeestereIngeborg GoethalsFilip De Vos

A1 Journal Article in APPLIED RADIATION AND ISOTOPES

PMMA based implant materials as a versatile technology platform for biomedical applications

Elke Van De WalleKarolien GellynckKen KersemansSandra Van VlierbergheFilip De VosMaria CornelissenPeter Dubruel

PMMA based implant materials: tailoring the bulk and surface properties

Elke Van De WalleKarolien GellynckKen KersemansSandra Van VlierbergheFilip De VosMaria CornelissenPeter Dubruel

Radiochemistry devoted to the production of monoamine oxidase (MAO-A and MAO-B) ligands for brain imaging with positron emission tomography

Ken KersemansNick Van LaekenFilip De Vos

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

2012

Enhanced vascularization surrounding an implantable continuous glucose sensor

Karolien GellynckValérie KodeckElke Van De WalleHeidi DeclercqKen KersemansLieven VlaminckPeter DubruelMaria Cornelissen

PMMA and PDMS surface modification to enhance sensor-associated vascularization

Karolien GellynckValerie KodekElke Van De WalleHeidi DeclercqKen KersemansLieven VlaminckPeter DubruelMaria Cornelissen

Radiolabeled gelatin type B analogues can be used for non-invasive visualisation and quantification of protein coatings on 3D porous implants

Ken KersemansTim DesmetChristian VanhovePeter DubruelFilip De Vos

A1 Journal Article in JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Simplified analytical HPLC purification of [11C]-raclopride

Nick Van LaekenKen KersemansFilip De Vos