Research Explorer

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Researcher

Karl Vandepoele

Awards & Distinctions

37 Results

2022

Ferroportin Q248H mutation was not found to be protective against malaria and anemia in children under 5 years living in South Kivu/Democratic Republic of Congo, an endemic area of Plasmodium infection

Yvette Lufungulo BahatiJoris DelangheGhislain Bisimwa BalalukaKarl VandepoeleJustin Cikomola CirhuzaAntoine Sadiki KishabongoJan Philippé

U Journal Article in Heliyon

2021

Deciphering molecular heterogeneity in pediatric AML using a cancer vs. normal transcriptomic approach

Barbara DepreterBarbara De MoerlooseKarl VandepoeleAnne UyttebroeckAn Van DammeEva TerrasBarbara DenysLaurence DedekenMarie-Francoise DresseJutte Van der Werff Ten Bosch et al.

A1 Journal Article in PEDIATRIC RESEARCH

Development of chronic myeloid leukemia in a patient previously diagnosed with a JAK2-positive myeloproliferative neoplasm

Sander De BruyneEVA STEELMarjan PetrickBarbara DenysKarl VandepoeleNadine Van RoySimon DegandtTimothy GhysHenk Louagie

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

2020

Clinical significance of TARP expression in pediatric acute myeloid leukemia

B. DepreterBarbara De MoerlooseKarl VandepoeleA. UyttebroeckA. Van DammeB. DenysL. DedekenM. -F. DresseJ. Van der Werff Ten BoschM. Hofmans et al.

Clinical significance of TARP expression in pediatric acute myeloid leukemia

Barbara DepreterBarbara De MoerlooseKarl VandepoeleAnne UyttebroeckAn Van DammeBarbara DenysLaurence DedekenMarie-Françoise DresseJutte Van Der Werff Ten BoschMattias Hofmans et al.

A1 Journal Article in HEMASPHERE

TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Barbara DepreterKarin WeeningKarl VandepoeleMagnus EssandBarbara De MoerlooseMaria ThemeliJacqueline CloosDiana HanekampIne MoorsINGE D'HONT et al.

A1 Journal Article in HAEMATOLOGICA

2019

A case report of acute panmyelosis with myelofibRosis (APMF) with a distinct molecular pattern

Emilie De MaertelaereKarl VandepoeleJoni Van der MeulenIne MoorsWillem DaneelsAnke DelieJan PhilippéCarolien BonroyKatrien DevreeseNadine Van Roy et al.

Clinical implications of measurable residual disease in AML : review of current evidence

Ine MoorsKarl VandepoeleJan PhilippéDries DeerenDominik SelleslagDimitri BreemsNicole StraetmansTessa KerreBarbara Denys

A1 Journal Article in CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Barbara DepreterMattias HofmansEva TerrasAnne UyttebroeckAn Van DammeAlina FersterJutte Van der Werff Ten BoschMarie-Françoise DresseKarl VandepoeleBarbara De Moerloose et al.

Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Barbara DepreterMattias HofmansEva TerrasAnne UyttebroeckAn Van DammeAlina FersterJutte van der Werff ten BoschMarie-Françoise DresseKarl VandepoeleBarbara De Moerloose et al.

Pinpointing a potential role for CLEC12B in cancer predisposition through familial exome sequencing

Charlotte DerpoorterKarl VandepoeleAraceli Diez FraileKatrien VandemeulebroeckeBram De WildeFranki SpelemanNadine Van RoyTim LammensGenevieve Laureys

A1 Journal Article in PEDIATRIC BLOOD & CANCER

Standardization of somatic variant classifications in solid and haematological tumours by a two-Level approach of biological and clinical classes : an Initiative of the Belgian ComPerMed Expert Panel

Guy FroyenMarie Le MercierEls LiermanKarl VandepoeleFriedel NolletElke BooneJoni Van der MeulenKoen JacobsSuzan LambinSara Vander Borght et al.

A1 Journal Article in CANCERS

TARP as immunotherapeutic target in AML expressed in the LSC compartment

Barbara DepreterKarin WeeningKarl VandepoeleM EssandBarbara De MoerlooseM ThemeliJ CloosD HanekampIne MoorsINGE D'HONT et al.

2018

A case of chronic eosinophilic leukemia with secondary transformation to acute myeloid leukemia

Mattias HofmansAnke DelieKarl VandepoeleNadine Van RoyJoni Van der MeulenJan PhilippéIne Moors

A2 Journal Article in LEUKEMIA RESEARCH REPORTS

Cancer-related mRNA expression analysis using a novel flow cytometry-based assay

Barbara DepreterJan PhilippéMAGALI MEULBarbara DenysKarl VandepoeleBarbara De MoerlooseTim Lammens

A1 Journal Article in CYTOMETRY PART B-CLINICAL CYTOMETRY

RNA-based FLT3-ITD allelic ratio is associated with outcome and ex vivo response to FLT3 inhibitors in pediatric AML

David G. J. CucchiBarbara DenysGertjan J. L. KaspersJeroen J. W. M. JanssenGert J. OssenkoppeleValerie de HaasC. Michel ZwaanMarry M. van den Heuvel-EibrinkJan PhilippéTamas Csikos et al.

A1 Journal Article in BLOOD

The NF1 hotspot in acute myeloid leukemia : what’s in a name?

Karl VandepoeleJoni Van der MeulenBarbara Denys

A1 Journal Article in LEUKEMIA

2017

A case report of a paediatric early T-cell precursor lymphoblastic leukemia

ANNE-SOPHIE DE KONINCKCatharina DhoogeBarbara DenysKarl VandepoeleNadine Van RoyMattias HofmansJan Philippé

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

A simple colorimetric assay for measuring fructosamine 3 kinase activity

Justin C CikomolaAntoine S KishabongoKarl VandepoeleMARIEKE DE MULDERPhilippe B KatchungaBram LaukensLoes van SchieHendrik GrootaertNico CallewaertMarijn Speeckaert et al.

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Exome sequencing to identify novel neuroblastoma predisposition genes

Charlotte DerpoorterKarl VandepoeleAraceli Diez FraileKatrien VandemeulebroeckeNadine Van RoyBram De WildeTim LammensGenevieve Laureys

In-house developed 15-gene sequencing panel for acute myeloid leukemia and myelodysplasia allows robust detection of genetic defects including FLT3-ITD and CEBPA mutations

Joni Van der MeulenBarbara DenysElien De LatterSteve LefeverToon RosseelWouter SteyaertGRETA VAN DER CRUYSSENIsabelle RottiersDavid CreytensJo Van Dorpe et al.

In-house developed 15-gene sequencing panel for acute myeloid leukemia and myelodysplasia allows robust detection of genetic defects including FLT3-ITD and CEBPA mutations

Joni Van der MeulenBarbara DenysElien De LatterSteve LefeverToon RosseelWouter SteyaertGRETA VAN DER CRUYSSENIsabelle RottiersDavid CreytensJo Van Dorpe et al.

Whole blood Fe isotopic signature in a sub-Saharan African population

Justin C CikomolaMaria del Rosario Florez GarciaMarta Costas RodriguezYulia AnoshkinaKarl VandepoelePhilippe B KatchungaAntoine S KishabongoMarijn SpeeckaertFrank VanhaeckeJoris Delanghe

A1 Journal Article in METALLOMICS

2016

Protocadherin-1 localization and cell-adhesion function in airway epithelial cells in asthma

Grissel Faura TellezBrigitte WM WillemseUilke BrouwerSusan Nijboer-BrinksmaKarl VandepoeleJacobien A NoordhoekIrene HeijinkMaaike de VriesNatalie P SmithersDirkje S Postma et al.

A1 Journal Article in PLOS ONE

The association between fructosamine-3 kinase 900C/G polymorphism, transferrin polymorphism and human herpesvirus-8 infection in diabetics living in South Kivu

Cirhuza Justin CikomolaKarl VandepoelePhilippe B KatchungaAntoine S KishabongoElizaveta PadalkoMarijn SpeeckaertJoris Delanghe

A1 Journal Article in ACTA TROPICA

2015

NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest

Vanessa AndriesKarl VandepoeleKatrien StaesGeert BerxPieter BogaertGert Van IsterdaelDaisy GinnebergeEef ParthoensJonathan VandenbusscheKris Gevaert et al.

A1 Journal Article in BMC CANCER

Protocadherin-1 binds to SMAD3 and suppresses TGF-β1-induced gene transcription

Grissel Faura TellezKarl VandepoeleUilke BrouwerHenk KoningRobin M EldermanTillie-Louise HackettBrigitte WM WillemseJohn HollowayFrans Van RoyGerard H Koppelman et al.

A1 Journal Article in AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The YPEL5-PPP1CB fusion transcript is detected in different hematological malignancies and in normal samples

Karl VandepoeleJan PhilippéBarbara Denys

A2 Journal Article in LEUKEMIA RESEARCH REPORTS

2013

Delta-protocadherins in health and disease

Irene KahrKarl VandepoeleFrans Van Roy

A1 Journal Article in Progress in Molecular Biology and Translational Science

2012

Functional analysis of the NBPF1 gene in cancer

Vanessa AndriesFrans Van RoyKarl Vandepoele

The NBPF gene family

Vanessa AndriesKarl VandepoeleFrans Van Roy

Bookchapter in Neuroblastoma : present and future

2010

Chibby interacts with NBPF1 and clusterin, two candidate tumor suppressors linked to neuroblastoma

Karl VandepoeleKatrien StaesVanessa AndriesFrans Van Roy

A1 Journal Article in EXPERIMENTAL CELL RESEARCH

2009

The NBPF1 Promoter Has Been Recruited from the Unrelated EVI5 Gene Before Simian Radiation

Karl VandepoeleVanessa AndriesFrans Van Roy

A1 Journal Article in MOLECULAR BIOLOGY AND EVOLUTION

2008

A constitutional translocation T(1;17)(P36.2;Q11.2) in a neuroblastoma patient disrupts NBPF1, a novel putative tumor suppressor gene

Vanessa AndriesKarl VandepoeleKatrien StaesFrans Van Roy

A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes

Karl VandepoeleVanessa AndriesNadine Van RoyKatrien StaesJo VandesompeleGenevieve LaureysEls De SmetGeert BerxFranki SpelemanFrans Van Roy

A1 Journal Article in PLOS ONE

2007

Insertion of an HERV(K) LTR in the intron of NBPF3 is not required for its transcriptional activity

Karl VandepoeleFrans Van Roy

A1 Journal Article in VIROLOGY

2005

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution

Karl VandepoeleNadine Van RoyKatrien StaesFranki SpelemanFrans Van Roy

A1 Journal Article in MOLECULAR BIOLOGY AND EVOLUTION