Research Explorer

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Researcher

Karel Miettinen

Awards & Distinctions

8 Results

2021

An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara

Lemeng DongAldo AlmeidaJacob PollierBekzod KhakimovJean-Etienne BassardKarel MiettinenDan StærkRahimi MehranCarl Erik OlsenMohammed Saddik Motawia et al.

A1 Journal Article in MOLECULAR BIOLOGY AND EVOLUTION

2019

Integrated metabolomics identifies CYP72A67 and CYP72A68 oxidases in the biosynthesis of Medicago truncatula oleanate sapogenins

Vered TzinJohn H SnyderDong Sik YangDavid V HuhmanBonnie S WatsonStacy N AllenYuhong TangKarel MiettinenPhilipp ArendtJacob Pollier et al.

A1 Journal Article in METABOLOMICS

2018

The TriForC database : a comprehensive up-to-date resource of plant triterpene biosynthesis

Karel MiettinenSabrina IñigoLukasz KreftJacob PollierChristof De BoAlexander BotzkiFrederik CoppensSoren BakAlain Goossens

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2017

A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules

James ReedMichael J StephensonKarel MiettinenBastiaan BrouwerAymeric LeveauPaul BrettRebecca JM GossAlain GoossensMaria A O'ConnellAnne Osbourn

A1 Journal Article in METABOLIC ENGINEERING

An endoplasmic reticulum-engineered yeast platform for overproduction of triterpenoids

Philipp ArendtKarel MiettinenJacob PollierRiet De RyckeNico CallewaertAlain Goossens

A1 Journal Article in METABOLIC ENGINEERING

The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis

Karel MiettinenJacob PollierDieter BuystPhilipp ArendtRené CsukSven SommerwerkTessa MosesJan MertensPrashant D SonawaneLaurens Pauwels et al.

A1 Journal Article in NATURE COMMUNICATIONS

2016

The basic helix-loop-helix transcription factor BIS2 is essential for monoterpenoid indole alkaloid production in the medicinal plant Catharanthus roseus

Alex Van MoerkerckePriscille SteensmaIvo GariboldiJaviera EspozPurin C PurnamaFabian SchweizerKarel MiettinenRobin Vanden BosscheRebecca De ClercqJohan Memelink et al.

A1 Journal Article in PLANT JOURNAL

2015

The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus

Alex Van MoerkerckePriscille SteensmaFabian SchweizerJacob PollierIvo GariboldiRichard PayneRobin Vanden BosscheKarel MiettinenJaviera EspozPurin Candra Purnama et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA