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Researcher
Justine Van Moorleghem
Profile
Projects
Publications
Activities
Awards & Distinctions
16
Results
2024
Interleukin-2 family cytokines IL-9 and IL-21 differentially regulate innate and adaptive type 2 immunity in asthma
Fabian Bick
Claudia Mariela Brenis Gómez
Inés Lammens
Justine Van Moorleghem
Caroline De Wolf
Sam Dupont
Laure Dumoutier
Neal P. Smith
Alexandra-Chloé Villani
Robin Browaeys
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2024
Interleukin-33-activated basophils promote asthma by regulating Th2 cell entry into lung tissue
Martijn Schuijs
Claudia Mariela Brenis Gómez
Fabian Bick
Justine Van Moorleghem
Manon Vanheerswynghels
Geert van Loo
Rudi Beyaert
David Voehringer
Richard M. Locksley
Hamida Hammad
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2024
2023
Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection
Jessica Vetters
Mary van Helden
Clint De Nolf
Sofie Rennen
Eva Cloots
Evelien Van De Velde
Farzaneh Fayazpour
Justine Van Moorleghem
Manon Vanheerswynghels
Karl Vergote
et al.
A1
Journal Article
in
ISCIENCE
2023
STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity
Bastiaan Maes
Farzaneh Fayazpour
Leen Catrysse
Guillaume Lornet
Evelien Van De Velde
Caroline De Wolf
Sofie De Prijck
Justine Van Moorleghem
Manon Vanheerswynghels
Kim Deswarte
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2023
2022
The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice
Bastiaan Maes
Ursula Smole
Matthias Vanderkerken
Kim Deswarte
Justine Van Moorleghem
Karl Vergote
Manon Vanheerswynghels
Caroline De Wolf
Sofie De Prijck
Nincy Debeuf
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2022
2021
CCR2-and Flt3-dependent inflammatory conventional type 2 dendritic cells are necessary for the induction of adaptive immunity by the human vaccine adjuvant system AS01
Cédric Bosteels
Kaat Fierens
Sofie De Prijck
Justine Van Moorleghem
Manon Vanheerswynghels
Caroline De Wolf
Aurelie Chalon
Catherine Collignon
Hamida Hammad
Arnaud M. Didierlaurent
et al.
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2021
2019
Prophylactic allergen immunotherapy with Der p 2 prevents murine asthma by regulating lung GM-CSF
Eline Haspeslagh
Manon Vanheerswynghels
Kim Deswarte
Justine Van Moorleghem
Alain Jacquet
Bart Lambrecht
Hamida Hammad
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2019
The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice
Nincy Debeuf
Assem Zhakupova
Regula Steiner
Sofie Van Gassen
Kim Deswarte
Farzaneh Fayazpour
Justine Van Moorleghem
Karl Vergote
Benjamin Pavie
Kelly Lemeire
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2019
The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF
Jessica Vetters
Mary van Helden
Sigrid Wahlen
Simon Tavernier
Arne Martens
Farzaneh Fayazpour
Karl Vergote
Manon Vanheerswynghels
Kim Deswarte
Justine Van Moorleghem
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2019
2018
Co-activation of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ in murine skin prevents worsening of atopic march
Julie Deckers
Nadia Bougarne
Viacheslav Mylka
Sofie Desmet
Astrid Luypaert
Michael Devos
Giel Tanghe
Justine Van Moorleghem
Manon Vanheerswynghels
Lode De Cauwer
et al.
A1
Journal Article
in
JOURNAL OF INVESTIGATIVE DERMATOLOGY
2018
Role of NKp46⁺ natural killer cells in house dust mite-driven asthma
Eline Haspeslagh
Mary van Helden
Kim Deswarte
Sofie De Prijck
Justine Van Moorleghem
Louis Boon
Hamida Hammad
Eric Vivier
Bart Lambrecht
A1
Journal Article
in
EMBO MOLECULAR MEDICINE
2018
2017
Airway epithelial cells are crucial targets of glucocorticoids in a mouse model of allergic asthma
Carina Klassen
Anna Karabinskaya
Lien Dejager
Sabine Vettorazzi
Justine Van Moorleghem
Fred Luehder
Sebastiaan H Meijsing
Jan P Tuckermann
Hanibal Bohnenberger
Claude Libert
et al.
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2017
Epicutaneous sensitization to house dust mite allergen requires interferon regulatory factor 4-dependent dermal dendritic cells
Julie Deckers
Dorine Sichien
Maud Plantinga
Justine Van Moorleghem
Manon Vanheerswynghels
Esther Hoste
Bernard Malissen
David Dombrowicz
Martin Guilliams
Karolien De Bosscher
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2017
House dust mite-driven asthma and allergen-specific T cells depend on B cells when the amount of inhaled allergen is limiting
Melissa Dullaers
Martijn Schuijs
Monique Willart
Kaat Fierens
Justine Van Moorleghem
Hamida Hammad
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2017
Myocardial infarction primes autoreactive T cells through activation of dendritic cells
Katrien Van Der Borght
Charlotte Scott
Veronika Nindl
Ann Bouché
Liesbet Martens
Dorine Sichien
Justine Van Moorleghem
Manon Vanheerswynghels
Sofie De Prijck
Yvan Saeys
et al.
A1
Journal Article
in
CELL REPORTS
2017
2016
Perinatal activation of the interleukin-33 pathway promotes type 2 immunity in the developing lung
Ismé De Kleer
Mirjam Kool
Marjolein JW de Bruijn
Monique Willart
Justine Van Moorleghem
Martijn Schuijs
Maud Plantinga
Rudi Beyaert
Emily Hams
Padraic G Fallon
et al.
A1
Journal Article
in
IMMUNITY
2016