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Researcher
Junhua Xie
Profile
Projects
Publications
Activities
Awards & Distinctions
15
Results
2024
An immunological puzzle : the adaptive immune system fuels Alzheimer’s disease pathology
Lien Van Hoecke
Jonas Castelein
Junhua Xie
Lore Van Acker
Griet Van Imschoot
Elien Van Wonterghem
Ine Vlaeminck
Daan Verhaege
Wouter Claeys
Keimpe Wierda
et al.
A1
Journal Article
in
BRAIN BEHAVIOR AND IMMUNITY
2024
The phytohormone abscisic acid enhances remyelination in mouse models of multiple sclerosis
Femke Van Gaever
Fleur Mingneau
Sam Vanherle
Yasmine Driege
Mira Haegman
Elien Van Wonterghem
Junhua Xie
Roosmarijn Vandenbroucke
Jerome J. A. Hendriks
Rudi Beyaert
et al.
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2024
The spreading and effects of human recombinant α-synuclein preformed fibrils in the cerebrospinal fluid of mice
Charysse Vandendriessche
Arnout Bruggeman
Joyce Foroozandeh
Lien Van Hoecke
Pieter Dujardin
Junhua Xie
Griet Van Imschoot
Elien Van Wonterghem
Jonas Castelein
Cristiano Lucci
et al.
A1
Journal Article
in
ENEURO
2024
2023
Bacterial extracellular vesicles : an emerging avenue to tackle diseases
Junhua Xie
Freddy Haesebrouck
Lien Van Hoecke
Roosmarijn Vandenbroucke
A1
Journal Article
in
TRENDS IN MICROBIOLOGY
2023
Gut microbiota regulates blood-cerebrospinal fluid barrier function and Aβ pathology
Junhua Xie
Arnout Bruggeman
Clint De Nolf
Charysse Vandendriessche
Griet Van Imschoot
Elien Van Wonterghem
Lars Vereecke
Roosmarijn Vandenbroucke
A1
Journal Article
in
EMBO JOURNAL
2023
Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling
Junhua Xie
Lien Cools
Griet Van Imschoot
Elien Van Wonterghem
Marie Pauwels
Ine Vlaeminck
Chloë De Witte
Samir EL Andaloussi
Keimpe Wierda
Lies De Groef
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2023
2022
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation
Lidia Yshii
Emanuela Pasciuto
Pascal Bielefeld
Loriana Mascali
Pierre Lemaitre
Marika Marino
James Dooley
Lubna Kouser
Stijn Verschoren
Vasiliki Lagou
et al.
A1
Journal Article
in
NATURE IMMUNOLOGY
2022
Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics
Marie Pauwels
Junhua Xie
Adam Ceroi
Sriram Balusu
Jonas Castelein
Elien Van Wonterghem
Griet Van Imschoot
Andrew Ward
Trevelyan R. Menheniott
Oskar Gustafsson
et al.
A1
Journal Article
in
BIOMATERIALS
2022
Studying the impact of the gastrointestinal bacteria on the brain, focusing on the blood-cerebrospinal fluid barrier and Alzheimer's disease
Junhua Xie
Roosmarijn Vandenbroucke
Freddy Haesebrouck
Lien Van Hoecke
Dissertation
2022
The impact of systemic inflammation on Alzheimer's disease pathology
Junhua Xie
Lien Van Hoecke
Roosmarijn Vandenbroucke
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2022
The tremendous biomedical potential of bacterial extracellular vesicles
Junhua Xie
Qiqiong Li
Freddy Haesebrouck
Lien Van Hoecke
Roosmarijn Vandenbroucke
A1
Journal Article
in
TRENDS IN BIOTECHNOLOGY
2022
2021
Anti-inflammatory mesenchymal stromal cell-derived extracellular vesicles improve pathology in Niemann-Pick type C disease
Lien Van Hoecke
Caroline Van Cauwenberghe
Verena Boerger
Arnout Bruggeman
Jonas Castelein
Griet Van Imschoot
Elien Van Wonterghem
Robin Dittrich
Wouter Claeys
Junhua Xie
et al.
A1
Journal Article
in
BIOMEDICINES
2021
Gastric Helicobacter suis infection partially protects against neurotoxicity in A 6-OHDA Parkinson’s disease mouse model
Helena Berlamont
Arnout Bruggeman
Eva Bauwens
Charysse Vandendriessche
Elien Clarebout
Junhua Xie
Sofie De Bruyckere
Griet Van Imschoot
Elien Van Wonterghem
Richard Ducatelle
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021
Involvement of the choroid plexus in the pathogenesis of Niemann-Pick disease type C
Lien Van Hoecke
Caroline Van Cauwenberghe
Kristina Dominko
Griet Van Imschoot
Elien Van Wonterghem
Jonas Castelein
Junhua Xie
Wouter Claeys
Charysse Vandendriessche
Anna Kremer
et al.
A1
Journal Article
in
FRONTIERS IN CELLULAR NEUROSCIENCE
2021
Low-grade peripheral inflammation affects brain pathology in the App(NL-G-F)mouse model of Alzheimer's disease
Junhua Xie
Nina Gorlé
Charysse Vandendriessche
Griet Van Imschoot
Elien Van Wonterghem
Caroline Van Cauwenberghe
Eef Parthoens
Evelien Van Hamme
Saskia Lippens
Lien Van Hoecke
et al.
A1
Journal Article
in
ACTA NEUROPATHOLOGICA COMMUNICATIONS
2021