Research Explorer

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Researcher

Julie Deckers

Awards & Distinctions

22 Results

2024

Amplification of Protein Expression by Self-Amplifying mRNA Delivered in Lipid Nanoparticles Containing a β-Aminoester Ionizable Lipid Correlates with Reduced Innate Immune Activation

Emily De LombaerdeXiaole CuiYong ChenZifu ZhongJulie DeckersGiulia MencarelliLisa OpsomerHaixiu WangJamie De BaereStefan Lienenklaus et al.

U Journal Article in ACS NANO

Combinatorial screening of biscarbamate ionizable lipids identifies a low reactogenicity lipid for lipid nanoparticle mRNA delivery

Emily De LombaerdeYong ChenTingting YeJulie DeckersGiulia MencarelliKim DeswarteHeleen LauwersRuben De CoenSabah KasmiSanne Bevers et al.

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Inhaled GM-CSF administered during ongoing pneumovirus infection alters myeloid and CD8 T cell immunity without affecting disease outcome

Nincy DebeufJulie DeckersSahine LameireCedric BosteelsHamida HammadBart Lambrecht

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

TCR transgenic clone selection guided by immune receptor analysis and single-cell RNA expression of polyclonal responders

Nincy DebeufSahine LameireManon VanheerswynghelsJulie DeckersCaroline De WolfWendy ToussaintRein VerbekeKevin VerstaenHamida HammadStijn Vanhee et al.

A2 Journal Article in ELIFE

2023

A Complement Atlas identifies interleukin 6 dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Karel Van DammeLevi HosteJozefien DeclercqElisabeth De LeeuwBastiaan MaesLiesbet MartensRoos ColmanRobin BrowaeysCedric BosteelsStijn Verwaerde et al.

A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Karel Van DammeLevi HosteJozefien DeclercqElisabeth De LeeuwBastiaan MaesLiesbet MartensRoos ColmanRobin BrowaeysCedric BosteelsStijn Verwaerde et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

2022

Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19 : an open-label randomized controlled trial

Elisabeth De LeeuwKarel Van DammeJozefien DeclercqCedric BosteelsBastiaan MaesSimon TavernierLaurent DetalleTrevor SmartSophie GlattNincy Debeuf et al.

A1 Journal Article in RESPIRATORY RESEARCH

Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment

Cedric BosteelsKarel Van DammeElisabeth De LeeuwJozefien DeclercqBastiaan MaesVictor BosteelsLevi HosteLeslie NaesensNincy DebeufJulie Deckers et al.

A1 Journal Article in CELL REPORTS MEDICINE

2021

Protection against allergies : microbes, immunity, and the farming effect

Julie DeckersBenjamin J. MarslandErika von Mutius

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

2019

How a farming environment protects from atopy

Julie DeckersBart LambrechtHamida Hammad

A1 Journal Article in CURRENT OPINION IN IMMUNOLOGY

Keratinocyte-intrinsic MHCII expression controls microbiota-induced Th1 cell responses

Samira TamoutounourSeong-Ji HanJulie DeckersMichael G. ConstantinidesCharlotte HurabielleOliver J. HarrisonNicolas BouladouxJonathan L. LinehanVerena M. LinkIvan Vujkovic-Cvijin et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2018

Co-activation of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ in murine skin prevents worsening of atopic march

Julie DeckersNadia BougarneViacheslav MylkaSofie DesmetAstrid LuypaertMichael DevosGiel TangheJustine Van MoorleghemManon VanheerswynghelsLode De Cauwer et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Langerhans cells : sensing the environment in health and disease

Julie DeckersHamida HammadEsther Hoste

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Molecular actions of PPARα in lipid metabolism and inflammation

Nadia BougarneBasiel WeyersSofie DesmetJulie DeckersDavid W RayBart StaelsKarolien De Bosscher

A1 Journal Article in ENDOCRINE REVIEWS

The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages

Viacheslav MylkaJulie DeckersDariusz RatmanLode De CauwerJonathan ThommisRiet De RyckeFrancis ImpensClaude LibertJan TavernierWim Vanden Berghe et al.

A1 Journal Article in AUTOPHAGY

2017

Epicutaneous sensitization to house dust mite allergen requires interferon regulatory factor 4-dependent dermal dendritic cells

Julie DeckersDorine SichienMaud PlantingaJustine Van MoorleghemManon VanheerswynghelsEsther HosteBernard MalissenDavid DombrowiczMartin GuilliamsKarolien De Bosscher et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Interplay between barrier epithelial cells and dendritic cells in allergic sensitization through the lung and the skin

Julie DeckersKarolien De BosscherBart LambrechtHamida Hammad

A1 Journal Article in IMMUNOLOGICAL REVIEWS

The skin as a central player in house dust mite allergy

Julie DeckersKarolien De BosscherHamida Hammad

2016

GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A

Andres E Barcala TabarrozziLuz AndreoneJulie DeckersCarla N CastroMaría L GimenoLaura AriolfoPaula M BerguerMaría Antunica-NoguerolAna C LibermanSabine Vettorazzi et al.

A1 Journal Article in SCIENTIFIC REPORTS

Overexpression of glucocorticoid-induced leucine zipper (GILZ) increases susceptibility to imiquimod-induced psoriasis and involves cutaneous activation of TGF-β1

Elena CarcellerMarlies BallegeerJulie DeckersCarlo RiccardiStefano BruscoliTino HochepiedClaude LibertPaloma Perez

A1 Journal Article in SCIENTIFIC REPORTS

2014

The increasing complexity of glucocorticoid receptor signaling and regulation

Sofie DesmetIlse BeckNadia BougarneDorien ClarisseJulie DeckersDariusz RatmanJan TavernierKarolien De Bosscher

A2 Journal Article in PROCEEDINGS OF THE BELGIAN ROYAL ACADEMIES OF MEDICINE

2013

Innate immune cells in asthma

Julie DeckersFilipe Branco MadeiraHamida Hammad

A1 Journal Article in TRENDS IN IMMUNOLOGY