Research Explorer

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Researcher

Jozefien Declercq

Publications & Research Data

Awards & Distinctions

24 Results

2026

Chitin Is a Potent Inducer of Type 2 Airway Inflammation Independent of Endogenous Chitinolytic Activity

Jozefien DeclercqHelena Catharine AegerterUrsula SmoleKarel Van DammeEllen KetelaereInés LammensCaroline De WolfKarl VergoteManon VanheerswynghelsSofie De Prijck et al.

U Journal Article in ALLERGY

2025

Respiratory immunity at the intersection of infection, vaccination and allergy : mechanisms and modulation of type 1 and type 2 inflammation in the upper and lower airways

Jozefien DeclercqBart LambrechtPhilippe GevaertStijn Vanhee

2024

Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection

Astrid MarchalElizabeth T. CirulliIva NeveuxEvangelos BellosRyan S. ThwaitesKelly M. Schiabor BarrettYu ZhangIvana Nemes-BokunMariya KalinovaAndrew Catchpole et al.

A2 Journal Article in HUMAN GENETICS AND GENOMICS ADVANCES

Repeated COVID-19 mRNA-based vaccination contributes to SARS-CoV-2 neutralizing antibody responses in the mucosa

Jozefien DeclercqSarah GerloSharon Van NevelNatalie De RuyckGabriële HoltappelsLiesbeth DelesieEls TobbackInés LammensNikita GerebtsovKoen Sedeyn et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

2023

A Complement Atlas identifies interleukin 6 dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Karel Van DammeLevi HosteJozefien DeclercqElisabeth De LeeuwBastiaan MaesLiesbet MartensRoos ColmanRobin BrowaeysCedric BosteelsStijn Verwaerde et al.

A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Karel Van DammeLevi HosteJozefien DeclercqElisabeth De LeeuwBastiaan MaesLiesbet MartensRoos ColmanRobin BrowaeysCedric BosteelsStijn Verwaerde et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

Chitinases and chitinase-like proteins in asthma

Jozefien DeclercqHamida HammadBart LambrechtUrsula Smole

A1 Journal Article in SEMINARS IN IMMUNOLOGY

Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice

Karel Van DammePieter HertensArne MartensElisabeth GilisDario PriemInge BruggemanAmelie FossoulJozefien DeclercqHelena Catharine AegerterAndy Wullaert et al.

A1 Journal Article in SCIENTIFIC REPORTS

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

Daniela MatuozzoEstelle TalouarnAstrid MarchalPeng ZhangJeremy ManryYoann SeeleuthnerYu ZhangAlexandre BolzeMatthieu ChaldebasBaptiste Milisavljevic et al.

A1 Journal Article in GENOME MEDICINE

RNA viruses alter house dust mite physiology and allergen production with no detected consequences for allergenicity

José Cristian Vidal‐QuistJozefien DeclercqStijn VanheeBart LambrechtJosé Gómez‐RialCarmen VidalEylem Aydogdu LohausStephane RombautsPedro Hernández‐Crespo

A1 Journal Article in INSECT MOLECULAR BIOLOGY

2022

COVID‐19 vaccination with BNT162b2 and ChAdOx1 vaccines has the potential to induce nasal neutralizing antibodies

Jozefien DeclercqEls TobbackStijn VanheeNatalie De RuyckSarah GerloPhilippe GevaertLinos Vandekerckhove

A1 Journal Article in ALLERGY

Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19 : an open-label randomized controlled trial

Elisabeth De LeeuwKarel Van DammeJozefien DeclercqCedric BosteelsBastiaan MaesSimon TavernierLaurent DetalleTrevor SmartSophie GlattNincy Debeuf et al.

A1 Journal Article in RESPIRATORY RESEARCH

Granulocyte colony-stimulating factor : missing link for stratification of type 2-high and type 2-low chronic rhinosinusitis patients

Sharon Van NevelJozefien DeclercqGabriële HoltappelsBart LambrechtClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inflammasomes and IL-1 family cytokines in SARS-CoV-2 infection : from prognostic marker to therapeutic agent

Jozefien DeclercqElisabeth De LeeuwBart Lambrecht

A1 Journal Article in CYTOKINE

Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment

Cedric BosteelsKarel Van DammeElisabeth De LeeuwJozefien DeclercqBastiaan MaesVictor BosteelsLevi HosteLeslie NaesensNincy DebeufJulie Deckers et al.

A1 Journal Article in CELL REPORTS MEDICINE

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Levi HosteLisa RoelsLeslie NaesensVictor BosteelsStijn VanheeSam DupontCedric BosteelsRobin BrowaeysNiels VandammeKevin Verstaen et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2021

Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19 : a meta-analysis

[missing] The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working GroupIsabel MurGracia María MateoMaria del Mar GutierrezVirginia PomarNatividad de BenitoNoemí CorbachoSilvia HerreraLucia MillanJessica Muñoz et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID) : a factorial, randomised, controlled trial

Jozefien DeclercqKarel Van DammeElisabeth De LeeuwBastiaan MaesCedric BosteelsSimon TavernierStefanie De BuyserRoos ColmanMaya HitesGil Verschelden et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

2020

Case report : convalescent plasma, a targeted therapy for patients with CVID and severe COVID-19

Karel Van DammeSimon TavernierNele Van RoyElisabeth De LeeuwJozefien DeclercqCedric BosteelsBastiaan MaesMarieke De BruyneDelfien BogaertVictor Bosteels et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC) : a structured summary of a study protocol for a randomised controlled trial

Cedric BosteelsBastiaan MaesKarel Van DammeElisabeth De LeeuwJozefien DeclercqANJA DELPORTEBENEDICTE DEMEYEREStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

A1 Journal Article in TRIALS

Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC) : a structured summary of a study protocol for a randomised controlled trial (vol 21, 491, 2020)

Cedric BosteelsBastiaan MaesKarel Van DammeElisabeth De LeeuwJozefien DeclercqAnja DelporteBenedicte DemeyereStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID) : a structured summary of a study protocol for a randomised controlled trial

Bastiaan MaesCedric BosteelsElisabeth De LeeuwJozefien DeclercqKarel Van DammeANJA DELPORTEBENEDICTE DEMEYEREStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

A1 Journal Article in TRIALS

Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID) : a structured summary of a study protocol for a randomised controlled trial (vol 21, 468, 2020)

Bastiaan MaesCedric BosteelsElisabeth De LeeuwJozefien DeclercqKarel Van DammeAnja DelporteBenedicte DemeyereStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV) : a structured summary of a study protocol for a randomised controlled trial

Jozefien DeclercqCedric BosteelsKarel Van DammeElisabeth De LeeuwBastiaan MaesAns VandecauterStefanie VermeerschAnja DelporteBénédicte DemeyereMarnik Vuylsteke et al.

A1 Journal Article in TRIALS