Research Explorer

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Researcher

Joyca De Temmerman

Awards & Distinctions

8 Results

2023

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Tineke VanderhaeghenSteven TimmermansMelanie EggermontDeepika WattsJolien VandewalleCharlotte WallaeysLouise NuyttensJoyca De TemmermanTino HochepiedSylviane Dewaele et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2021

Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs

Zifu ZhongSéan Mc CaffertyLisa OpsomerHaixiu WangHanne HuysmansJoyca De TemmermanStefan LienenklausJoão Portela CataniFrancis CombesNiek Sanders

A1 Journal Article in MOLECULAR THERAPY

In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation

Séan Mc CaffertyJoyca De TemmermanTasuku KitadaJacob R. BecraftRon WeissDarrell J. IrvineMathias DevreeseSiegrid De BaereFrancis CombesNiek Sanders

A1 Journal Article in MOLECULAR THERAPY

2019

Expression kinetics and innate immune response after electroporation and LNP-mediated delivery of a self-amplifying mRNA in the skin

Hanne HuysmansZifu ZhongJoyca De TemmermanBarbara L MuiYing K TamSéan Mc CaffertyArlieke GitselsDaisy VanrompayNiek Sanders

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

Improving the repeatability and efficacy of intradermal electroporated self-replicating mRNA

Hanne HuysmansJoyca De TemmermanZifu ZhongSéan Mc CaffertyFrancis CombesFreddy HaesebrouckNiek Sanders

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

Mononuclear but not polymorphonuclear phagocyte depletion increases circulation times and improves mammary tumor-homing efficiency of donor bone marrow-derived monocytes

Francis CombesAlexandros Marios SofiasSéan Mc CaffertyHanne HuysmansJoyca De TemmermanSjoerd HakEvelyne MeyerNiek Sanders

A1 Journal Article in CANCERS

2018

mRNA therapeutics deliver a hopeful message

Zifu ZhongSéan Mc CaffertyFrancis CombesHanne HuysmansJoyca De TemmermanArlieke GitselsDaisy VanrompayJoão Portela CataniNiek Sanders

A1 Journal Article in NANO TODAY

2017

Evaluation of a xenogeneic vascular endothelial growth factor-2 vaccine in two preclinical metastatic tumor models in mice

Sofie DeniesBregje LeymanHanne HuysmansFrancis CombesSéan Mc CaffertyLaetitia CiccheleroMarjan SteppeJoyca De TemmermanNiek Sanders

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY