Research Explorer

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Researcher

Joris Lammens

Awards & Distinctions

15 Results

2023

Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids

Alexander LamootJoris LammensEmily De LombaerdeZifu ZhongMark GontsarikYong ChenThomas De BeerBruno De Geest

A1 Journal Article in BIOMATERIALS SCIENCE

2022

Development and characterisation of a continuous freeze-drying technology for unit doses

Joris LammensChris VervaetThomas De Beer

2021

A NIR-based study of desorption kinetics during continuous spin freeze-drying

Laurens LeysGust NuyttenJoris LammensPieter-Jan Van BockstalJos CorverChris VervaetThomas De Beer

A1 Journal Article in PHARMACEUTICS

Development and application of a mechanistic cooling and freezing model of the spin freezing step within the framework of continuous freeze-drying

Gust NuyttenSusan Ríos RevattaPieter-Jan Van BockstalAshish KumarJoris LammensLaurens LeysBrecht VanbillemontJos CorverChris VervaetThomas De Beer

A1 Journal Article in PHARMACEUTICS

Increasing angiogenesis factors in hypoxic diabetic wound conditions by siRNA delivery : additive effect of LbL-gold nanocarriers and desloratadine-induced lysosomal escape

Elnaz Shaabani SichaniMaryam SharifiaghdamJoris LammensHerlinde De KeersmaeckerChris VervaetThomas De BeerElahe MotevaseliMohammad Hossein GhahremaniParvin MansouriStefaan De Smedt et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Spin freezing and its impact on pore size, tortuosity and solid state

Joris LammensNiloofar Moazami GoudarziLaurens LeysGust NuyttenPieter-Jan Van BockstalChris VervaetMatthieu BooneThomas De Beer

A1 Journal Article in PHARMACEUTICS

2020

4D micro-computed X-ray tomography as a tool to determine critical process and product information of spin freeze-dried unit doses

Brecht VanbillemontJoris LammensWannes GoethalsChris VervaetMatthieu BooneThomas De Beer

A1 Journal Article in PHARMACEUTICS

A primary drying model-based comparison of conventional batch freeze-drying to continuous spin-freeze-drying for unit doses

Laurens LeysBrecht VanbillemontPieter-Jan Van BockstalJoris LammensGust NuyttenJos CorverChris VervaetThomas De Beer

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

In-situ X-ray imaging of sublimating spin-frozen solutions

Wannes GoethalsBrecht VanbillemontJoris LammensThomas De BeerChris VervaetMatthieu Boone

A1 Journal Article in MATERIALS

Lyophilization and nebulization of pulmonary surfactant-coated nanogels for siRNA inhalation therapy

Pieterjan MerckxJoris LammensGust NuyttenBram BogaertRoberta GuagliardoTania MaesChris VervaetThomas De BeerStefaan De SmedtKoen Raemdonck

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

2019

Dry amorphisation of mangiferin, a poorly water-soluble compound, using mesoporous silica

Adrienn BaánPeter AdriaensensJoris LammensRené Delgado HernandezWim Vanden BergheLuc PietersChris VervaetFilip Kiekens

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Dual chamber cartridges in a continuous pharmaceutical freeze-drying concept : determination of the optimal dynamic infrared heater temperature during primary drying

Laurens De MeyerJoris LammensBrecht VanbillemontPieter-Jan Van BockstalJos CorverChris VervaetWolfgang FriessThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

2018

Potential of near-infrared chemical imaging as process analytical technology tool for continuous freeze-drying

Davinia BrouckaertLaurens De MeyerBrecht VanbillemontPieter-Jan Van BockstalJoris LammensSéverine MortierJos CorverChris VervaetIngmar NopensThomas De Beer

A1 Journal Article in ANALYTICAL CHEMISTRY

The relevance of shear, sedimentation and diffusion during spin freezing, as potential first step of a continuous freeze-drying process for unit doses

Joris LammensSéverine MortierLaurens De MeyerBrecht VanbillemontPieter-Jan Van BockstalSimon Van HerckJos CorverIngmar NopensValérie VanhoorneBruno De Geest et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

2017

Modelling the primary drying step for the determination of the optimal dynamic heating pad temperature in a continuous pharmaceutical freeze-drying process for unit doses

Laurens De MeyerJoris LammensSéverine MortierBrecht VanbillemontPieter-Jan Van BockstalJos CorverIngmar NopensChris VervaetThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS