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Researcher
Jorick Franceus
Profile
Projects
Publications
Activities
Awards & Distinctions
23
Results
2022
Building mutational bridges between carbohydrate-active enzymes
Jorick Franceus
Jolien Lormans
Tom Desmet
A1
Journal Article
in
CURRENT OPINION IN BIOTECHNOLOGY
2022
Identification of mercaptoacetamide-based HDAC6 inhibitors via a lean inhibitor strategy : screening, synthesis, and biological evaluation
Silke Geurs
Dorien Clarisse
Freya Baele
Jorick Franceus
Tom Desmet
Karolien De Bosscher
Matthias D'hooghe
A1
Journal Article
in
CHEMICAL COMMUNICATIONS
2022
Insertions and deletions in protein evolution and engineering
Simone Savino
Tom Desmet
Jorick Franceus
A1
Journal Article
in
BIOTECHNOLOGY ADVANCES
2022
2021
Discovery of a kojibiose hydrolase by analysis of specificity-determining correlated positions in Glycoside Hydrolase Family 65
Emma De Beul
Alana Jongbloet
Jorick Franceus
Tom Desmet
A1
Journal Article
in
MOLECULES
2021
Engineering of a thermostable biocatalyst for the synthesis of 2-O-glucosylglycerol
Jorick Franceus
Zorica Ubiparip
Koen Beerens
Tom Desmet
A1
Journal Article
in
CHEMBIOCHEM
2021
Evolution of phosphorylases from N-acetylglucosaminide hydrolases in family GH3
Jorick Franceus
Jolien Lormans
Lore Cools
Matthias D'hooghe
Tom Desmet
A1
Journal Article
in
ACS CATALYSIS
2021
Exploration of GH94 sequence space for enzyme discovery reveals a novel glucosylgalactose phosphorylase specificity
Marc De Doncker
Chloé De Graeve
Jorick Franceus
Koen Beerens
Vladimír Křen
Helena Pelantová
Ronny Vercauteren
Tom Desmet
A1
Journal Article
in
CHEMBIOCHEM
2021
β-Glucan phosphorylases in carbohydrate synthesis
Zorica Ubiparip
Marc De Doncker
Koen Beerens
Jorick Franceus
Tom Desmet
A1
Journal Article
in
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
2021
2020
Sucrose phosphorylase and related enzymes in glycoside hydrolase family 13 : discovery, application and engineering
Jorick Franceus
Tom Desmet
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
Synthesis, trehalase hydrolytic resistance and inhibition properties of 4-and 6-substituted trehalose derivatives
Shari Dhaene
Johan Van der Eycken
Koen Beerens
Jorick Franceus
Tom Desmet
Jurgen Caroen
A1
Journal Article
in
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2020
2019
Discovery of novel cellodextrin phosphorylases : where bioinformatics meets biochemistry
Zorica Ubiparip
Jorick Franceus
Nídia Martins
Koen Beerens
Tom Desmet
C3
Conference
2019
Exploring and engineering the functional diversity of glycoside phosphorylases
Jorick Franceus
Tom Desmet
Dissertation
2019
Rational design of an improved transglucosylase for production of the rare sugar nigerose
Jorick Franceus
Shari Dhaene
Hannes Decadt
Judith Vandepitte
Jurgen Caroen
Johan Van der Eycken
Koen Beerens
Tom Desmet
A1
Journal Article
in
CHEMICAL COMMUNICATIONS
2019
Structural comparison of a promiscuous and a highly specific sucrose 6F-phosphate phosphorylase
Jorick Franceus
Nikolas Capra
Tom Desmet
Andy-Mark W.H. Thunnissen
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2019
Synthesis of indoline‐based benzhydroxamic acids as potential HDAC6 inhibitors
Yves Depetter
Silke Geurs
Jorick Franceus
Damijan Knez
Tom Desmet
Karolien De Bosscher
Olivier De Wever
Stanislav Gobec
Matthias D'hooghe
A1
Journal Article
in
CHEMISTRYSELECT
2019
2018
Assessment of the trifluoromethyl ketone functionality as an alternative zinc-binding group for selective HDAC6 inhibition
Yves Depetter
Silke Geurs
Flore Vanden Bussche
Rob De Vreese
Jorick Franceus
Tom Desmet
Olivier De Wever
Matthias D'hooghe
A1
Journal Article
in
MEDCHEMCOMM
2018
Chemoenzymatic approach toward the synthesis of 3-O-(α/β)-glucosylated 3-hydroxy-β-lactams
Lena Decuyper
Jorick Franceus
Shari Dhaene
Maarten Debruyne
Kevin Vandoorne
Nicola Piens
Griet Dewitte
Tom Desmet
Matthias D'hooghe
A1
Journal Article
in
ACS OMEGA
2018
Exploring the sequence diversity in glycoside hydrolase family 13_18 reveals a novel glucosylglycerol phosphorylase
Jorick Franceus
Lena Decuyper
Matthias D'hooghe
Tom Desmet
A1
Journal Article
in
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
2018
Thermostable alpha-glucan phosphorylases : characteristics and industrial applications
Zorica Ubiparip
Koen Beerens
Jorick Franceus
Ronny Vercauteren
Tom Desmet
A1
Journal Article
in
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
2018
2017
Correlated positions in protein evolution and engineering
Jorick Franceus
Tom Verhaeghe
Tom Desmet
A1
Journal Article
in
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
2017
Glucosylglycerate phosphorylase, an enzyme with novel specificity involved in compatible solute metabolism
Jorick Franceus
Denise Pinel
Tom Desmet
A1
Journal Article
in
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
2017
Synthesis of potent and selective HDAC6 inhibitors bearing a cyclohexane- or cycloheptane-annulated 1,5-benzothiazepine scaffold
Rob De Vreese
Lisa Galle
Yves Depetter
Jorick Franceus
Tom Desmet
Kristof Van Hecke
Veronick Benoy
Ludo Van Den Bosch
Matthias D'hooghe
A1
Journal Article
in
CHEMISTRY-A EUROPEAN JOURNAL
2017
2016
Diastereoselective synthesis of 3-acetoxy-4-(3-aryloxiran-2-yl)azetidin-2-ones and their transformation into 3,4-oxolane-fused bicyclic β-lactams
Nicola Piens
Sven De Craene
Jorick Franceus
Karen Mollet
Kristof Van Hecke
Tom Desmet
Matthias D'hooghe
A1
Journal Article
in
ORGANIC & BIOMOLECULAR CHEMISTRY
2016