Research Explorer

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Researcher

Jordy De Coninck

Awards & Distinctions

6 Results

2025

Development and validation of a high-throughput screening pipeline of compound libraries to target EMT

Sven JonckheereJoachim TaminauJamie AdamsJef HaerinckJordy De ConinckJeroen VerstappeKato De ClercqEvelien PeetersAlexander GheldofEva De Smedt et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2024

ZEB2 drives intra-tumor heterogeneity and skin squamous cell carcinoma formation with distinct EMP transition states

Jeroen VerstappeNicolas SkrypekJordy De ConinckBieke SoenJoachim TaminauMarianthi TatariKenneth BruneelNele LoretKato De ClercqCaroline Van den Broecke et al.

A1 Journal Article in ISCIENCE

2022

Distinct transcriptional programs in ascitic and solid cancer cells induce different responses to chemotherapy in high-grade serous ovarian cancer

Nele LoretNiels VandammeJordy De ConinckJoachim TaminauKato De ClercqGillian BlanckeSven JonckheereSteven GoossensKelly LemeireSofie De Prijck et al.

A1 Journal Article in MOLECULAR CANCER RESEARCH

Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state

Farzaneh GhazaviJelle HuysentruytJordy De ConinckStephanie KourulaSofie MartensBehrouz HassanniaTim WartewigTatyana DivertRia RoelandtBastian Popper et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2021

XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells

Adam WahidaMadeleine MuellerAndreas HiergeistBastian PopperKatja SteigerCaterina BrancaMarkus TschurtschenthalerThomas EngleitnerSainitin DonakondaJordy De Coninck et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

2020

The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype

Niels VandammeGeertrui DeneckerKenneth BruneelGillian BlanckeOzden AkayJoachim TaminauJordy De ConinckEva De SmedtNicolas SkrypekWouter Van Loocke et al.

A1 Journal Article in CANCER RESEARCH