Research Explorer

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Researcher

Jonathan Thommis

Awards & Distinctions

15 Results

2024

Selective modulation of the human glucocorticoid receptor compromises GR chromatin occupancy and recruitment of p300/CBP and the Mediator complex

Laura Van MoortelAnnick VerheeJonathan ThommisRené HoutmanDiana MelchersLouis DelhayeChloé Van LeeneMadeleine HellemansKris GevaertSven Eyckerman et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

2023

Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells

Dorien ClarisseStefan PrekovicPhilip VlummensEleni StaessensKarlien Van WesemaelJonathan ThommisDaria FijalkowskaGuillaume AckeWilbert ZwartIlse M. Beck et al.

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

2022

Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets

Laura Van MoortelJonathan ThommisBrecht MaertensAn StaesDorien ClarisseDelphine De SutterClaude LibertOnno C. MeijerSven EyckermanKris Gevaert et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

2019

Mechanisms underlying the functional cooperation between PPARα and GRα to attenuate inflammatory responses

Nadia BougarneViacheslav MylkaDariusz RatmanIlse BeckJonathan ThommisLode De CauwerJan TavernierBart StaelsClaude LibertKarolien De Bosscher

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2018

Co-activation of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ in murine skin prevents worsening of atopic march

Julie DeckersNadia BougarneViacheslav MylkaSofie DesmetAstrid LuypaertMichael DevosGiel TangheJustine Van MoorleghemManon VanheerswynghelsLode De Cauwer et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages

Viacheslav MylkaJulie DeckersDariusz RatmanLode De CauwerJonathan ThommisRiet De RyckeFrancis ImpensClaude LibertJan TavernierWim Vanden Berghe et al.

A1 Journal Article in AUTOPHAGY

2017

Compound A influences gene regulation of the dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment

Sofie DesmetNadia BougarneLaura Van MoortelLode De CauwerJonathan ThommisM VuylstekeDariusz RatmanR HoutmanJan TavernierKarolien De Bosscher

A1 Journal Article in SCIENTIFIC REPORTS

Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies

Dorien ClarisseJonathan ThommisKarlien Van WesemaelRene HoutmanDariusz RatmanJan TavernierFritz OffnerIlse BeckKarolien De Bosscher

A1 Journal Article in ONCOTARGET

Daucane esters from laserwort (Laserpitium latifolium L.) inhibit cytokine and chemokine production in human lung epithelial cells

Visnja PopovicJan GoemanJonathan ThommisArne HeyerickJurgen CaroenJohan Van der EyckenKarolien De Bosscher

A1 Journal Article in PHYTOMEDICINE

Glucocorticoid receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

Ioanna PettaNadia BougarneJolien VandewalleLien DejagerSofie VandevyverMarlies BallegeerSofie DesmetJonathan ThommisLode De CauwerSam Lievens et al.

A1 Journal Article in SCIENTIFIC REPORTS

Plasmodium berghei NK65 in combination with IFN-γ induces endothelial glucocorticoid resistance via sustained activation of p38 and JNK

Karolina A. ZielińskaLode De CauwerSofie KnoopsKristof Van der MolenAlexander SneyersJonathan ThommisJ. Brian De SouzaGhislain OpdenakkerKarolien De BosscherPhilippe E. Van den Steen

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2016

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα

Dariusz RatmanViacheslav MylkaNadia BougarneMichal PawlakSandrine CaronNathalie HennuyerRéjane PaumelleLode De CauwerJonathan ThommisMark H Rider et al.

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2014

Cofactor profiling of the glucocorticoid receptor from a cellular environment

Sofie DesmetLien DejagerDorien ClarisseJonathan ThommisDiana MelchersNiek BastiaensenRob RuijtenbeekIlse BeckClaude LibertRenée Houtman et al.

Bookchapter in Steroid receptors : methods and protocols

Determining the cofactor profile of the glucocorticoid receptor in lymphoid malignancies using MARCoNI

Dorien ClarisseSofie DesmetJonathan ThommisIlse BeckKarolien De Bosscher

Determining the coregulator profile of the endogenous glucocorticoid receptor in lymphoid malignancies using MARCoNI

Dorien ClarisseDariusz RatmanSofie DesmetJonathan ThommisRené HoutmanKarolien De BosscherIlse Beck