Research Explorer

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Researcher

Jonathan Elegheert

Awards & Distinctions

13 Results

2020

Structure and assembly mechanism of the signaling complex mediated by human CSF-1 (vol 23, pg 1621, 2015)

Jan FélixSteven De MunckKenneth VerstraeteLeander MeurisNico CallewaertJonathan ElegheertSavvas Savvides

2017

Structural dissection of Shewanella oneidensis old yellow enzyme 4 bound to a Meisenheimer complex and (nitro)phenolic ligands

Jonathan ElegheertAnn BrigeJozef Van BeeumenSavvas Savvides

A1 Journal Article in FEBS LETTERS

2015

Structure and assembly mechanism of the signaling complex mediated by human CSF-1

Jan FélixSteven De MunckKenneth VerstraeteLeander MeurisNico CallewaertJonathan ElegheertSavvas Savvides

A1 Journal Article in STRUCTURE

2014

The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence

Yurong WenEster BehielsJan FélixJonathan ElegheertBjorn VergauwenBart DevreeseSavvas Savvides

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2013

Human IL-34 and CSF-1 establish structurally similar extracellular assemblies with their common hematopoietic receptor

Jan FélixJonathan ElegheertIrina GutscheAlexander ShkumatovYurong WenNathalie BrackeErwin PannecouckeIsabel VandenbergheBart DevreeseDmitri Svergun et al.

A1 Journal Article in STRUCTURE

2012

Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1

Jonathan ElegheertNathalie BrackePhilippe PouliotIrina GutscheAlexander V ShkumatovNicolas TarbouriechKenneth VerstraeteAnaïs BekaertWim P BurmeisterDmitri I Svergun et al.

A1 Journal Article in NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural biology of Colony-Stimulating Factor 1 (CSF-1) signaling and decoy complexes

Jonathan ElegheertSavvas Savvides

2011

Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles

Jonathan ElegheertAmbroise DesfossesAlexander V ShkumatovXiongwu WuNathalie BrackeKenneth VerstraeteKathleen Van CraenenbroeckBernard R BrooksDmitri I SvergunBjorn Vergauwen et al.

A1 Journal Article in STRUCTURE

Inducible production of recombinant human Flt3 ectodomain variants in mammalian cells and preliminary crystallographic analysis of Flt3 ligand-receptor complexes

Kenneth VerstraeteBert RemmerieJonathan ElegheertBéatrice LintermansGuy HaegemanPeter VanhoenackerKathleen Van CraenenbroeckSavvas Savvides

A1 Journal Article in ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS

Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex

Kenneth VerstraeteGonzalez VandriesscheMariska JanuarJonathan ElegheertAlexander V ShkumatovAmbroise DesfossesKathleen Van CraenenbroeckDmitri I SvergunIrina GutscheBjorn Vergauwen et al.

A1 Journal Article in BLOOD

2010

Glutathione import in Haemophilus influenzae Rd is primed by the periplasmic heme-binding protein HbpA

Bjorn VergauwenJonathan ElegheertAnn DansercoerBart DevreeseSavvas Savvides

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards structural studies of the old yellow enzyme homologue SYE4 from Shewanella oneidensis and its complexes at atomic resolution

Jonathan ElegheertDebbie van den HemelIna DixJan StoutJozef Van BeeumenAnn BrigéSavvas Savvides

A1 Journal Article in ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS

2008

Towards a better understanding of extracellular cytokine receptor biology: the initial characterization of a lectin/R complex

Bert RemmerieKoenraad VerstraeteJonathan ElegheertBjorn VergauwenSavvas Savvides