Research Explorer

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Researcher

Jonatan Linus Gabre

Awards & Distinctions

6 Results

2024

ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition

Marcus BorenäsGanesh UmapathyDan E. LindWei-Yun LaiJikui GuanJoel JohanssonEva JennischeAlexander SchmidtYeshwant KurheJonatan Linus Gabre et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational approaches to facilitate the identification of novel therapeutic targets in neuroblastoma and other ALK-driven cancers

Jonatan Linus GabreJimmy Van den EyndenRuth Palmer

Preclinical exploration of the DNA damage response pathway using the interactive neuroblastoma cell line explorer CLEAN

Jonatan Linus GabrePeter MerseburgerArne ClaeysJoachim SiawSarah-Lee BekaertFranki SpelemanBengt HallbergRuth H PalmerJimmy Van den Eynden

A2 Journal Article in NAR CANCER

2023

ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression

Tzu-Po ChuangWei-Yun LaiJonatan Linus GabreDan E. LindGanesh UmapathyAbdulmalik A. BokhariBengt BergmanLinnea KristensonFredrik B. ThorénAnh Le et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2021

ATR inhibition enables complete tumour regression in ALK-driven NB mouse models

Joanna SzydzikDan E. LindBadrul ArefinYeshwant KurheGanesh UmapathyJoachim Tetteh SiawArne ClaeysJonatan Linus GabreJimmy Van den EyndenBengt Hallberg et al.

A1 Journal Article in NATURE COMMUNICATIONS

Loss of RET promotes mesenchymal identity in neuroblastoma cells

Joachim T. SiawJonatan Linus GabreEzgi UçkunMarc VignyWancun ZhangJimmy Van den EyndenBengt HallbergRuth H. PalmerJikui Guan

A1 Journal Article in CANCERS