Research Explorer

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Researcher

Jonas Janssens

Awards & Distinctions

13 Results

2020

Radiosynthesis, in vitro and preliminary biological evaluation of [F-18]2-amino-4-((2-((3-fluorobenzyl)oxy)benzyl)(2-((3-(fluoromethyl)benzyl)oxy)benzyl)amino) butanoic acid, a novel alanine serine cysteine transporter 2 inhibitor-based positron emission tomography tracer

Tristan BaguetJakob BoutonJonas JanssensGlenn PauwelynJeroen VerhoevenBenedicte DescampsSerge Van CalenberghChristian VanhoveFilip De Vos

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

2019

4''-O-Alkylated α-galactosylceramide analogues as iNKT-cell antigens : synthetic, biological, and structural studies

Jonas JanssensAruna BitraJing WangTine DecruyKoen VenkenJohan Van der EyckenDirk ElewautDirk ZajoncSerge Van Calenbergh

A1 Journal Article in CHEMMEDCHEM

A molecular switch in mouse CD1d modulates natural killer T cell activation by α-galactosylsphingamides

Jing WangJoren GuillaumeJonas JanssensSoumya G. RemeshGe YingAruna BitraSerge Van CalenberghDirk Zajonc

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Broadening the message : a nanovaccine co-loaded with messenger RNA and α-GalCer induces antitumor immunity through conventional and natural killer T cells

Rein VerbekeIne LentackerKarine BreckpotJonas JanssensSerge Van CalenberghStefaan De SmedtHeleen Dewitte

A1 Journal Article in ACS NANO

Ceramide-templated macrolactams : total synthesis and biological evaluation of macrocyclic α-galactosylceramide analogues and their aglycons

Jonas JanssensJohan Van der EyckenSerge Van Calenbergh

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

α-Galactosylceramide analogues as iNKT-cell antigens : synthesis, biological evaluation and structural analysis

Jonas JanssensJohan Van der EyckenSerge Van Calenbergh

2018

4"-O-alkylated α-galactosylceramide analogues as iNKT cell antigens : synthetic, biological and structural studies

Jonas JanssensJing WangAruna BitraTine DecruyKoen VenkenJohan Van der EyckenDirk ElewautDirk ZajoncSerge Van Calenbergh

Regioselective ring opening of 1,3-dioxane-type acetals in carbohydrates

Jonas JanssensMartijn RisseeuwJohan Van der EyckenSerge Van Calenbergh

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

2017

Efficient divergent synthesis of new immunostimulant 4″-modified α-galactosylceramide analogues

Jonas JanssensTine DecruyKoen VenkenToshiyuki SekiSimon KrolsJohan Van der EyckenMoriya TsujiDirk ElewautSerge Van Calenbergh

A1 Journal Article in ACS MEDICINAL CHEMISTRY LETTERS

Galactosylsphingamides : new α-GalCer analogues to probe the F’-pocket of CD1d

Joren GuillaumeJing WangJonas JanssensSoumya G RemeshMartijn RisseeuwTine DecruyMathy FroeyenDirk ElewautDirk M ZajoncSerge Van Calenbergh

A1 Journal Article in SCIENTIFIC REPORTS

2016

A PMB-protecting group strategy for the divergent synthesis of 4”-modified alpha-galactosylceramide analogues

Jonas JanssensJohan Van der EyckenSerge Van Calenbergh

A practical approach to the synthesis of new 4”-modified α-galactosylceramide analogues

Jonas JanssensJohan Van der EyckenSerge Van Calenbergh

Synthesis and biological evaluation of phytosphingosine modified α-GalCer analogues as potential immunomodulating agents

Jonas JanssensJohan Van der EyckenSerge Van Calenbergh