Research Explorer

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Researcher

Jonas Castelein

Publications & Research Data

Awards & Distinctions

8 Results

2026

Base barrier cells provide compartmentalization of choroid plexus, brain and CSF

Daan VerhaegeClint De NolfLore Van AckerWouter ClaeysJonas CasteleinElien Van WonterghemGriet Van ImschootPieter DujardinWard De SpiegelaereEsther Hoste et al.

A1 Journal Article in NATURE NEUROSCIENCE

2025

Gut microbiota modulates CNS barrier function in murine model for multiple sclerosis

Junhua XieMarlies BurgelmanPieter DujardinJonas CasteleinGriet Van ImschootElien Van WonterghemHannah LernoutSjoerd SchettersCharysse VandendriesscheLien Van Hoecke et al.

A1 Journal Article in FLUIDS AND BARRIERS OF THE CNS

2024

An immunological puzzle : the adaptive immune system fuels Alzheimer’s disease pathology

Lien Van HoeckeJonas CasteleinJunhua XieLore Van AckerGriet Van ImschootElien Van WonterghemIne VlaeminckDaan VerhaegeWouter ClaeysKeimpe Wierda et al.

A1 Journal Article in BRAIN BEHAVIOR AND IMMUNITY

The spreading and effects of human recombinant α-synuclein preformed fibrils in the cerebrospinal fluid of mice

Charysse VandendriesscheArnout BruggemanJoyce ForoozandehLien Van HoeckePieter DujardinJunhua XieGriet Van ImschootElien Van WonterghemJonas CasteleinCristiano Lucci et al.

A1 Journal Article in ENEURO

2023

Experimental hepatic encephalopathy causes early but sustained glial transcriptional changes

Wouter ClaeysLien Van HoeckeHannah LernoutClint De NolfGriet Van ImschootElien Van WonterghemDaan VerhaegeJonas CasteleinAnja GeertsChristophe Van Steenkiste et al.

A1 Journal Article in JOURNAL OF NEUROINFLAMMATION

2022

Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics

Marie PauwelsJunhua XieAdam CeroiSriram BalusuJonas CasteleinElien Van WonterghemGriet Van ImschootAndrew WardTrevelyan R. MenheniottOskar Gustafsson et al.

A1 Journal Article in BIOMATERIALS

2021

Anti-inflammatory mesenchymal stromal cell-derived extracellular vesicles improve pathology in Niemann-Pick type C disease

Lien Van HoeckeCaroline Van CauwenbergheVerena BoergerArnout BruggemanJonas CasteleinGriet Van ImschootElien Van WonterghemRobin DittrichWouter ClaeysJunhua Xie et al.

A1 Journal Article in BIOMEDICINES

Involvement of the choroid plexus in the pathogenesis of Niemann-Pick disease type C

Lien Van HoeckeCaroline Van CauwenbergheKristina DominkoGriet Van ImschootElien Van WonterghemJonas CasteleinJunhua XieWouter ClaeysCharysse VandendriesscheAnna Kremer et al.

A1 Journal Article in FRONTIERS IN CELLULAR NEUROSCIENCE