Research Explorer

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Researcher

Joline Goossens

Awards & Distinctions

38 Results

2013

Chronic exposure to the mycotoxin T-2 promotes oral absorption of chlortetracycline in pigs

Joline GoossensMathias DevreeseFrank PasmansAnn OsselaereSiegrid De BaereElin VerbruggheFreddy HaesebrouckPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Influence of deoxynivalenol and T-2 toxin on the oral bioavailability of antibiotics in pigs

Joline GoossensSiska CroubelsFrank PasmansPatrick De Backer

The mycotoxin T-2 inhibits hepatic cytochrome P4503A activity in pigs

Joline GoossensLies De BockAnn OsselaereElin VerbruggheMathias DevreeseKoen BousseryJan Van BocxlaerPatrick De BackerSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Toxic effects of dietary exposure to T-2 toxin on intestinal and hepatic biotransformation enzymes and drug transporter systems in broiler chickens

Ann OsselaereShaoji LiLies De BockMathias DevreeseJoline GoossensVirginie VandenbrouckeJan Van BocxlaerKoen BousseryFrank PasmansAn Martel et al.

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Toxicokinetic study and absolute oral bioavailability of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens

Ann OsselaereMathias DevreeseJoline GoossensVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

2012

A modified glucomannan mycotoxin-adsorbing agent counteracts the reduced weight gain and diminishes cecal colonization of Salmonella Typhimurium in T-2 toxin exposed pigs

Elin VerbruggheSiska CroubelsVirginie VandenbrouckeJoline GoossensPatrick De BackerMia EeckhoutSarah De SaegerFilip BoyenBregje LeymanAlexander Van Parys et al.

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

Effect of T-2 toxin and a yeast-extract feed additive on the oral bioavailability of chlortetracycline in pigs

Joline GoossensFrank PasmansVirginie VandenbrouckeElin VerbruggheMathias DevreeseAnn OsselaereSiegrid De BaereFreddy HaesebrouckPatrick De BackerSiska Croubels

Efficacy and safety testing of mycotocoxin-detoxifying agents in broilers following the European Food Safety Authority guidelines

Ann OsselaereMathias DevreeseAnneleen WatteynVirginie VandenbrouckeJoline GoossensVeerle HautekietMia EeckhoutSarah De SaegerSiegrid De BaerePatrick De Backer et al.

A1 Journal Article in POULTRY SCIENCE

In vitro and in vivo safety testing of mycotoxin detoxifying agents

Mathias DevreeseJoline GoossensAnn OsselaereVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

Influence of mycotoxins and a mycotoxin adsorbing agent on the oral bioavailability of commonly used antibiotics in pigs

Joline GoossensVirginie VandenbrouckeFrank PasmansSiegrid De BaereMathias DevreeseAnn OsselaereElin VerbruggheFreddy HaesebrouckSarah De SaegerMia Eeckhout et al.

A1 Journal Article in TOXINS

Interaction between tylosin and bentonite clay from a pharmacokinetic perspective

Mathias DevreeseAnn OsselaereJoline GoossensVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in VETERINARY JOURNAL

Interaction between tylosin and bentonite clay from a pharmacokinetic perspective

Mathias DevreeseAnn OsselaereJoline GoossensSiegrid De BaerePatrick De BackerSiska Croubels

New bolus models for in vivo efficacy testing of mycotoxin detoxifying agents in relation to EFSA guidelines, assessed using deoxynivalenol in broiler chickens

Mathias DevreeseAnn OsselaereJoline GoossensVirginie VandenbrouckeSiegrid De BaereMia EeckhoutPatrick De BackerSiska Croubels

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

Porcine intestinal epithelial barrier disruption by the Fusarium mycotoxins deoxynivalenol and T-2 toxin promotes transepithelial passage of doxycycline and paromomycin

Joline GoossensFrank PasmansElin VerbruggheVirginie VandenbrouckeSiegrid De BaereEvelyne MeyerFreddy HaesebrouckPatrick De BackerSiska Croubels

A1 Journal Article in BMC VETERINARY RESEARCH

T-2 toxin induced Salmonella Typhimurium intoxication results in decreased Salmonella numbers in the cecum contents of pigs, despite marked effects on Salmonella-host cell interactions

Elin VerbruggheVirginie VandenbrouckeMaarten DhaenensNeil ShearerJoline GoossensSarah De SaegerMia EeckhoutKatharina D'HerdeArthur ThompsonDieter Deforce et al.

A1 Journal Article in VETERINARY RESEARCH

Toxic effects of dietary exposure to T-2 toxin on intestinal and hepatic CYP450 in broilers

Ann OsselaereShaoji LiLies De BockMathias DevreeseJoline GoossensVirginie VandenbrouckeFrank PasmansAn MartelPatrick De BackerSiska Croubels

Toxicokinetic study of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens

Ann OsselaereMathias DevreeseJoline GoossensVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

2011

Combined effects of deoxynivalenol and Salmonella Typhimurium on intestinal inflammation in the pig

Virginie VandenbrouckeFrank PasmansAn MartelElin VerbruggheJoline GoossensKim Van DeunFilip BoyenPatrick De BackerFreddy HaesebrouckSiska Croubels

Cytotoxic effects of the Fusarium mycotoxins deoxynivalenol, T2-toxin, fumonisin B1 and zearalenone on intestinal porcine epithelial cells derived from the jejunum

Joline GoossensFrank PasmansVirginie VandenbrouckeEvelyne MeyerFreddy HaesebrouckPatrick De BackerSiska Croubels

Double benefit: a modified glucomannan mycotoxin-adsorbing agent counteracts T-2 toxin related reduced weight gain and limits Salmonella Typhimurium infections in pigs

Elin VerbruggheSiska CroubelsVirginie VandenbrouckeJoline GoossensPatrick De BackerMia EeckhoutSarah De SaegerFilip BoyenBregje LeymanAlexander Van Parys et al.

Double trouble: the interaction between the mycotoxin deoxynivalenol and salmonellosis in the pig

Virginie VandenbrouckeSiska CroubelsElin VerbruggheJoline GoossensFreddy HaesebrouckPatrick De BackerFrank Pasmans

Een gewijzigde glucomannaan mycotoxine binder en T2-toxine in het voeder verminderen de kolonisatie van Salmonella Typhimurium in varkens

Elin VerbruggheSiska CroubelsVirginie VandenbrouckeMia EeckhoutSarah De SaegerJoline GoossensPatrick De BackerBregje LeymanAlexander Van ParysFilip Boyen et al.

Effects of the mycotoxins deoxynivalenol and T-2 toxin on the pathogenesis of a Salmonella TYphimurium infection in pigs

Virginie VandenbrouckeElin VerbruggheSiska CroubelsAn MartelJoline GoossensKim Van DeunFilip BoyenArthur ThompsonNeil ShearerSarah De Saeger et al.

Influence of mycotoxin detoxifying agents on the plasma pharmacokinetics and tissue residues of amoxicillin and oxytetracycline in poultry

Ann OsselaereJoline GoossensSiegrid De BaereSarah De SaegerMia EeckhoutPatrick De BackerSiska Croubels

Nieuwe Europese (EFSA) richtlijnen om de efficaciteit van mycotoxine binders en modifiers aan te tonen

Mathias DevreeseAnn OsselaereJoline GoossensSiegrid De BaerePatrick De BackerSiska Croubels

Quantitative determination of T-2 toxin, HT-2 toxin, deoxynivalenol and deepoxy-deoxynivalenol in animal body fluids using LC-MS/MS detection

Siegrid De BaereJoline GoossensAnn OsselaereMathias DevreeseVirginie VandenbrouckePatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

T-2 toxin alters host-pathogen interactions of Salmonella Typhimurium in pigs

Elin VerbruggheSiska CroubelsVirginie VandenbrouckeMia EeckhoutSarah De SaegerJoline GoossensPatrick De BackerArthur ThompsonNeil ShearerFilip Boyen et al.

T-2 toxin causes decreased intestinal colonization of Salmonella Typhimurium in pigs associated with altered gene expression

Elin VerbruggheVirginie VandenbrouckeSiska CroubelsMia EeckhoutSarah De SaegerJoline GoossensPatrick De BackerArthur ThompsonNeil ShearerBregje Leyman et al.

The mycotoxin deoxynivalenol potentiates intestinal inflammation by Salmonella Typhimurium in porcine ileal loops

Virginie VandenbrouckeSiska CroubelsAn MartelElin VerbruggheJoline GoossensKim Van DeunFilip BoyenArthur ThompsonNeil ShearerPatrick De Backer et al.

A1 Journal Article in PLOS ONE

2010

Deoxynivalenol alters the interactions of Salmonella Typhimurium with porcine intestinal epithelial cells and macrophages

Virginie VandenbrouckeFrank PasmansElin VerbruggheJoline GoossensFreddy HaesebrouckPatrick De BackerSiska Croubels

Development of a quantitative method for the determination of Fusarium mycotoxins in pig plasma using liquid chromatography tandem mass spectrometry

Siegrid De BaereJoline GoossensVirginie VandenbrouckeAnn OsselaerePatrick De BackerSiska Croubels

Quantitative determination of deoxynivalenol and related compounds in animal plasma using LC-MS/MS as part of a toxicokinetic study

Siegrid De BaereAnn OsselaereMathias DevreeseJoline GoossensVirginie VandenbrouckePatrick De BackerSiska Croubels

2009

Deoxynivalenol (DON) induces increased invasion of Salmonella Typhimurium in alveolar pig macrophages by activation of extracellular regulated kinase (ERK)

Elin VerbruggheVirginie VandenbrouckeSiska CroubelsJoline GoossensPatrick De BackerFilip BoyenFreddy HaesebrouckFrank Pasmans

Influence of Fusarium toxins on intestinal epithelial cell permeability

Joline GoossensFrank PasmansVirginie VandenbrouckeElin VerbruggheFreddy HaesebrouckPatrick De BackerSiska Croubels

Mycotoxins in pig feed: influence on the gut and interaction with Salmonella Typhimurium infections

Elin VerbruggheVirginie VandenbrouckeFrank PasmansJoline GoossensFreddy HaesebrouckPatrick De BackerSiska Croubels

Reduced expression of intestinal P-glycoprotein following ingestion of deoxynivalenol (DON) contaminated feed in pigs

Sara Van der HeydenJoline GoossensVirginie VandenbrouckeGriet VercauterenKoen ChiersFrank PasmansFreddy HaesebrouckPatrick De BackerSiska CroubelsRichard Ducatelle

Reduced expression of intestinal P-glycoprotein following ingestion of deoxynivalenol (DON) contaminated feed in pigs

Joline GoossensVirginie VandenbrouckeSara Van der HeydenRichard DucatelleFrank PasmansFreddy HaesebrouckPatrick De BackerSiska Croubels

Reduced expression of intestinal P-glycoprotein following ingestion of deoxynivalenol (DON) contaminated feed in pigs

Sara Van der HeydenJoline GoossensVirginie VandenbrouckeGriet VercauterenKoen ChiersFrank PasmansFreddy HaesebrouckPatrick De BackerSiska CroubelsRichard Ducatelle