Research Explorer

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Researcher

Jolien Souffriau

Awards & Distinctions

11 Results

2020

Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system

Kelly Van LooverenSteven TimmermansTineke VanderhaeghenCharlotte WallaeysMarlies BallegeerJolien SouffriauMelanie EggermontJolien VandewalleLise Van WyngeneKarolien De Bosscher et al.

A1 Journal Article in EMBO REPORTS

Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis

Lise Van WyngeneTineke VanderhaeghenSteven TimmermansJolien VandewalleKelly Van LooverenJolien SouffriauCharlotte WallaeysMelanie EggermontSam ErnstEvelien Van Hamme et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium

Jolien SouffriauSteven TimmermansTineke VanderhaeghenCharlotte WallaeysKelly Van LooverenLindsy AelbrechtSylviane DewaeleJolien VandewalleEvy GoossensSerge Verbanck et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

2019

A general introduction to glucocorticoid biology

Steven TimmermansJolien SouffriauClaude Libert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

Karen DendonckerSteven TimmermansJolien VandewalleMelanie EggermontJoanna LempiäinenVille PaakinahoEvelien Van HammeSylviane DewaeleSofie VandevyverMarlies Ballegeer et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2018

A screening assay for Selective Dimerizing Glucocorticoid Receptor Agonists and Modulators (SEDIGRAM) that are effective against acute inflammation

Jolien SouffriauMelanie EggermontSara Van RyckeghemKelly Van LooverenLise Van WyngeneEvelien Van HammeMarnik VuylstekeRudi BeyaertKarolien De BosscherClaude Libert

A1 Journal Article in SCIENTIFIC REPORTS

Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice

Marlies BallegeerKelly Van LooverenSteven TimmermansMelanie EggermontSofie VandevyverFabien Henri TheryKaren DendonckerJolien SouffriauJolien VandewalleLise Van Wyngene et al.

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

Mechanistic insights into the protective impact of zinc on sepsis

Jolien SouffriauClaude Libert

A1 Journal Article in CYTOKINE & GROWTH FACTOR REVIEWS

Targeting TNF-induced acute inflammation by making use of SEDIGRAM or zinc

Jolien SouffriauClaude Libert

Using the inbred mouse strain SPRET/EiJ to provide novel insights in inflammation and infection research

Steven TimmermansJolien SouffriauJolien VandewalleLise Van WyngeneKelly Van LooverenTineke VanderhaeghenClaude Libert

A1 Journal Article in MAMMALIAN GENOME

2015

Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation

Lien DejagerKaren DendonckerMelanie EggermontJolien SouffriauFilip Van HauwermeirenMonique WillartElien Van WonterghemThomas NaessensMarlies BallegeerSofie Vandevyver et al.

A1 Journal Article in MUCOSAL IMMUNOLOGY