Research Explorer

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Researcher

Jolanda van Hengel

Awards & Distinctions

118 Results

2025

Exploring aneuploidies in two-center isolated bovine embryonic stem cell lines : implications for cultured meat production

Chloë DeelkensElly De VlieghereMario Van PouckeMasaki KinoshitaJeffrey AaldersLieven ThorrezBert DevriendtAnn Van SoomLuc PeelmanBjörn Menten et al.

A2 Journal Article in FUTURE FOODS

Human stem cell models for Marfan syndrome : a brief overview of the rising star in disease modelling

Jeffrey AaldersLaura Muiño MosqueraJolanda van Hengel

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Nattokinase as a novel food-grade enzyme for long term cell subculture

Maria OlenicChloë DeelkensJolanda van HengelCatharina De SchauwerLieven Thorrez

A1 Journal Article in FOOD RESEARCH INTERNATIONAL

Review : livestock cell types with myogenic differentiation potential : considerations for the development of cultured meat

Maria OlenicChloë DeelkensEmma HeymanElly De VlieghereX. ZhengJolanda van HengelCatharina De SchauwerBert DevriendtStefaan De SmetLieven Thorrez

A1 Journal Article in ANIMAL

2024

Combinatorial effects of surface plasma-treating and aligning PCL/chitosan nanofibers on the behavior of stem cell-derived cardiomyocytes for cardiac tissue engineering

Laurens LégerSheida AliakbarshiraziPegah ZahedifarJeffrey AaldersPascal Van Der VoortNathalie De GeyterRino MorentJolanda van HengelRouba Ghobeira

A1 Journal Article in APPLIED SURFACE SCIENCE

Generation of a human induced pluripotent stem cell line UGENTi002-A from an arrhythmogenic cardiomyopathy patient carrying the c.817C>T DSP heterozygous variant and isogenic control using CRISPR/Cas9 editing

Laurens LégerJeffrey AaldersNina HeymansKiara Van Acker-VerbercktLéa De BleeckerePaul CouckeBjörn MentenBarbara BauceLibero VitielloAlessandra Rampazzo et al.

A1 Journal Article in STEM CELL RESEARCH

Improving cardiac differentiation of human pluripotent stem cells by targeting ferroptosis

Jeffrey AaldersLaurens LégerBehrouz HassanniaVera GoossensTom Vanden BergheJolanda van Hengel

A1 Journal Article in REGENERATIVE THERAPY

Indirect correlative light and electron microscopy (iCLEM) : a novel pipeline for multiscale quantification of structure from molecules to organs

Heather L StruckmanNicolae MoiseBieke VanslembrouckNathan RothackerZhenhui ChenJolanda van HengelSeth H WeinbergRengasayee Veeraraghavan

A1 Journal Article in MICROSCOPY AND MICROANALYSIS

One cell type, infinite possibilities : utilizing human pluripotent stem cells for modeling arrhythmogenic cardiomyopathy and cardiac tissue engineering

Laurens LégerJolanda van HengelMartina Calore

Photoporation-mediated spatial intracellular delivery of stem cell-derived cardiomyocytes

Laurens LégerChloë De ClercqJeffrey AaldersKiara Van Acker-VerbercktKevin BraeckmansJolanda van Hengel

A2 Journal Article in METHODSX

Three-dimensional co-culturing of stem cell-derived cardiomyocytes and cardiac fibroblasts reveals a role for both cell types in Marfan-related cardiomyopathy

Jeffrey AaldersLaurens LégerLouis Van der MeerenSanjay SinhaAndre SkirtachJulie De BackerJolanda van Hengel

A1 Journal Article in MATRIX BIOLOGY

2023

Generation of human induced pluripotent stem cell line UGENTi001-A from a patient with Marfan syndrome carrying a heterozygous c.7754 T > C variant in FBN1 and the isogenic control UGENT001-A-1 using CRISPR/Cas9 editing

Jeffrey AaldersLaurens LégerAnthony DemolderLaura Muiño MosqueraPaul CouckeBjörn MentenJulie De BackerJolanda van Hengel

A1 Journal Article in STEM CELL RESEARCH

Modelling Marfan-related cardiomyopathy in vitro using human induced pluripotent stem cells

Jeffrey AaldersJolanda van HengelJulie De Backer

2022

A20 controls RANK-dependent osteoclast formation and bone physiology

Arne MartensPieter HertensDario PriemVagelis RinotasTheodore MeletakosMeropi GennadiLisette Van HoveEls LouagieJulie CoudenysAmélie De Muynck et al.

A1 Journal Article in EMBO REPORTS

Bovine embryonic stem cells : a challenging approach for the development of cultured meat

Chloë DeelkensPetra Van DammeCatharina De SchauwerBert DevriendtLieven ThorrezJolanda van Hengel

Bovine pluripotent stem cells : a challenging approach for the development of cultured meat

Chloë DeelkensPetra Van DammeAnn Van SoomCatharina De SchauwerBert DevriendtLieven ThorrezJolanda van Hengel

Dielectric barrier discharge-treated aligned electrospun chitosan/polycaprolactone nanofibers for cardiac tissue engineering

Laurens LégerSheida AliakbarshiraziPegah ZahedifarNathalie De GeyterJeffrey AaldersRino MorentJolanda van HengelRouba Ghobeira

In vitro modelling of Marfan-related cardiomyopathy points to abnormalities in mechanobiology of the heart muscle cells

Jeffrey AaldersLaurens LégerLouis Van der MeerenPatrick SipsLaura Muiño MosqueraAndre SkirtachSanjay SinhaJulie De BackerJolanda van Hengel

In vitro modelling of Marfan-related cardiomyopathy points to abnormalities in mechanobiology of the heart muscle cells

Jeffrey AaldersLaurens LégerLouis Van der MeerenPatrick SipsLaura Muiño MosqueraAndre SkirtachSanjay SinhaJulie De BackerJolanda van Hengel

Microscopic visualization of cell-cell adhesion complexes at micro and nanoscale

Bieke VanslembrouckJian-hua ChenCarolyn LarabellJolanda van Hengel

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Plakophilin3 loss leads to increased adenoma formation and rectal prolapse in APCmin mice

Rahul RaghavanNavami KoyandeRohit BeherNeha ChetlangiaMukda RamadwarShital PawadeRahul ThoratJolanda van HengelTetyana SklyarovaFrans Van Roy et al.

A1 Journal Article in BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

2021

Bovine pluripotent stem cells : a challenging approach for the development of cultured meat

Chloë DeelkensMaria OlenicPetra Van DammeCatharina De SchauwerBert DevriendtLieven ThorrezJolanda van Hengel

Effects of fibrillin mutations on the behaviour of heart muscle cells in Marfan syndrome

Jeffrey AaldersLaurens LégerLouis Van der MeerenNatasja Van den VrekenAndre SkirtachSanjay SinhaJulie De BackerJolanda van Hengel

In vitro modelling of Marfan related cardiomyopathy points to abnormalities in mechanobiology of the heart muscle cells

Jeffrey AaldersLaurens LégerLouis Van der MeerenNatasja Van den VrekenAndre SkirtachSanjay SinhaJulie De BackerJolanda van Hengel

Liquid marbles : a cost-effective platform to generate cardiospheres from co-cultured cardiomyocytes and cardiac fibroblast for disease modelling

Jeffrey AaldersLaurens LégerSergio LeddaJolanda van Hengel

Myofibers in a 3D environment hold the future for human food security

Chloë DeelkensMaria OlenicBert DevriendtCatharina De SchauwerLieven ThorrezJolanda van Hengel

Photothermal nanofibres enable safe engineering of therapeutic cells

Ranhua XiongDawei HuaJelter Van HoeckDominika BerdeckaLaurens LégerStijn De MunterJuan FraireLaurens RaesAranit HarizajFélix Sauvage et al.

A1 Journal Article in NATURE NANOTECHNOLOGY

Use of transparent liquid marble : microbioreactor to culture cardiospheres

Jeffrey AaldersLaurens LégerDavide PirasJolanda van HengelSergio Ledda

Bookchapter in Next generation culture platforms for reliable in vitro models

2020

Effects of fibrillin mutations on the behavior of heart muscle cells in Marfan syndrome

Jeffrey AaldersLaurens LégerLouis Van der MeerenNatasja Van den VrekenAndre SkirtachSanjay SinhaJulie De BackerJolanda van Hengel

A1 Journal Article in SCIENTIFIC REPORTS

Exploring the three-dimensional organization of the murine intercalated disc and unraveling the connection between the intercalated disc and the cytoskeleton of cardiac myocytes

Bieke VanslembrouckJolanda van HengelMarjolijn Rijnard

Liquid marble technology to create cost-effective 3D cardiospheres as a platform for in vitro drug testing and disease modelling

Jeffrey AaldersLaurens LégerTim TuerlingsSergio LeddaJolanda van Hengel

A2 Journal Article in METHODSX

Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice

Tim PietersEllen SandersHuiyu TianJolanda van HengelFrans Van Roy

A1 Journal Article in BMC DEVELOPMENTAL BIOLOGY

Time for rethinking the different β‐actin transgenic mouse models?

Bieke VanslembrouckChristophe AmpeJolanda van Hengel

A1 Journal Article in CYTOSKELETON

Unraveling the ultrastructural details of αT‐catenin‐deficient cell‐cell contacts between heart muscle cells by the use of FIB‐SEM

Bieke VanslembrouckAnna KremerFrans Van RoySaskia LippensJolanda van Hengel

A1 Journal Article in JOURNAL OF MICROSCOPY

2019

Armc8 is a evolutionarily conserved armadillo protein involved in cell-cell adhesion complexes through multiple molecular interactions

Ismail Sahin GülPaco HulpiauEllen SandersFrans Van RoyJolanda van Hengel

A1 Journal Article in BIOSCIENCE REPORTS

Cell communication in cardiac muscle cells

Jolanda van HengelJeffrey AaldersNatasja Van den VrekenMarleen De GrooteBieke Vanslembrouck

Closer look at heart cell connectors

Bieke VanslembrouckAnna KremerSaskia LippensJolanda van Hengel

Deletion of mucosa-associated lymphoid tissue lymphoma translocation protein 1 in mouse T cells protects against development of autoimmune arthritis but leads to spontaneous osteoporosis

Elisabeth GilisDjoere GaublommeJens StaalKoen VenkenMaarten DhaenensStijn LambrechtJulie CoudenysTine DecruyNadia SchryversYasmine Driege et al.

A1 Journal Article in ARTHRITIS & RHEUMATOLOGY

In vitro characterization of stem cell derived Marfan syndrome cardiomyocytes

Jeffrey AaldersLaurens LégerNatasja Van den VrekenSanjay SinhaJulie De BackerJolanda van Hengel

In vitro modelling of Marfan syndrome using stem cell derived cardiomyocytes

Jeffrey AaldersLaurens LégerNatasja Van den VrekenJulie De BackerJolanda van Hengel

Intercalated discs : specialized cytoskeletal anchors in cardiac muscle

Jolanda van HengelMaarten De SmetAnna KremerSaskia LippensMarjolijn RenardChristophe AmpeBieke Vanslembrouck

Modelling Marfan syndrome in vitro using human stem cell derived cardiomyocytes and fibroblasts

Jeffrey AaldersLaurens LégerNatasja Van den VrekenJulie De BackerJolanda van Hengel

Optimized protocol for the three-dimensional visualization and reconstruction of intercellular junctions in cardiac muscle using SBF-SEM and FIB-SEM

Bieke VanslembrouckAnna KremerBenjamin PavieFrans Van RoySaskia LippensJolanda van Hengel

Robust protocol for feeder-free adaptation of cryopreserved human pluripotent stem cells

Jeffrey AaldersNatasja Van den VrekenMina PopovicSwati MishraBjörn HeindryckxJolanda van Hengel

A1 Journal Article in IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Visualizing murine cardiac intercellular junctions and their links in 3D

Bieke VanslembrouckAnna KremerSaskia LippensJolanda van Hengel

2018

3-D reconstructions of intercellular junctions of the intercalated disc and their connection to complexes of the excitation-contraction coupling unit of cardiomyocytes

Bieke VanslembrouckAnna KremerBenjamin PavieFrans Van RoySaskia LippensJolanda van Hengel

A heart for fibrillin : spatial arrangement in adult wild-type murine myocardial tissue

Felke SteijnsJolanda van HengelPatrick SipsJulie De BackerMarjolijn Renard

A1 Journal Article in HISTOCHEMISTRY AND CELL BIOLOGY

Functional measurements of stem cell derived cardiomyocytes to model Marfan syndrome in vitro

Jeffrey AaldersNatasja Van den VrekenFelipe SerranoSanjay SinhaJulie De BackerJolanda van Hengel

Interactions between stem cell derived cardiomyocytes and extra cellular matrix to model Marfan syndrome in vitro

Jeffrey AaldersNatasja Van den VrekenJulie De BackerJolanda van Hengel

RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism

Alberto García-MariscalKarine PeyrollierAstrid BasseEsben PedersenRalph RühlJolanda van HengelCord Brakebusch

A2 Journal Article in SMALL GTPASES

Robust protocol for feeder-free adaptation of frozen pluripotent stem cells using StemFlex

Jeffrey AaldersNatasja Van den VrekenBjörn HeindryckxJolanda van Hengel

Stem cell derived cardiomyocytes extra cellular matrix to model Marfan syndrome in vitro

Jeffrey AaldersNatasja Van den VrekenJulie De BackerJolanda van Hengel

Stem cell derived cardiomyocytes to model Marfan syndrome in vitro

Jeffrey AaldersNatasja Van den VrekenJulie De BackerJolanda van Hengel

Three-dimensional reconstruction of the intercalated disc including the intercellular junctions by applying volume scanning electron microscopy

Bieke VanslembrouckAnna KremerBenjamin PavieFrans Van RoySaskia LippensJolanda van Hengel

Three-dimensional reconstruction of the intercalated disc including the intercellular junctions by applying volume scanning electron microscopy

Bieke VanslembrouckAnna KremerBenjamin PavieFrans Van RoySaskia LippensJolanda van Hengel

A1 Journal Article in HISTOCHEMISTRY AND CELL BIOLOGY

2017

Cardiomyocyte cell junctions : unraveling the mechanobiology with 3-D volume electron microscopy

Bieke VanslembrouckMarjolijn RenardSaskia LippensAnna KremerJolanda van Hengel

FIB-SEM and SBF-SEM to unravel the cardiomyocyte cell junctions

Bieke VanslembrouckAnna KremerSaskia LippensMarjolijn RenardJolanda van Hengel

From pluripotent stem cells to cardiomyocytes

Jeffrey AaldersNatasja Van den VrekenJolanda van Hengel

Maturation of human pluripotent stem cell-derived cardiomyocytes

Jolanda van HengelNatasja Van den VrekenJeffrey Aalders

Structure-function studies in mouse embryonic stem cells using recombinase-mediated cassette exchange

Tim PietersLieven HaenebalckeKenneth BruneelNiels VandammeTino HochepiedJolanda van HengelDagmar WirthGeert BerxJody J HaighFrans Van Roy et al.

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

Ultra structure of the intercalated disc in murine cardiomyocard revealed by volume electron microscopy

Jolanda van HengelAnna KremerSaskia LippensBieke Vanslembrouck

2016

Beta-catenin and plakoglobin expression during zebrafish tooth development and replacement

Barbara VerstraetenJolanda van HengelAnn Huysseune

A1 Journal Article in PLOS ONE

Inactivation of p120 catenin in mice disturbs intrahepatic bile duct development and aggravates liver carcinogenesis

Jolanda van HengelCeline Van den BroekeTim PietersLouis LibbrechtIlse HofmannFrans Van Roy

A1 Journal Article in EUROPEAN JOURNAL OF CELL BIOLOGY

Molecular evolution of the armadillo repeat superfamily and characterization of representative members in key model organisms

Ismail Sahin GülFrans Van RoyJolanda van Hengel

Ultra structure of the intercalated disc in murine cardiomyocard revealed by volume electron microscopy

Bieke VanslembrouckSteven Van WoenselAnna KremerSaskia LippensJolanda van Hengel

p120 Catenin-mediated stabilization of E-cadherin is essential for primitive endoderm specification

Tim PietersSteven GoossensLieven HaenebalckeVanessa AndriesAgata StryjewskaRiet De RyckeKelly LemeireTino HochepiedDanny HuylebroeckGeert Berx et al.

A1 Journal Article in PLOS GENETICS

αT-catenin in restricted brain cell types and its potential connection to autism

Stephen Sai FolmsbeeDouglas R WilcoxKoen TybergheinPieter De BleserWarren G TourtellotteJolanda van HengelFrans Van RoyCara J Gottardi

A2 Journal Article in JOURNAL OF MOLECULAR PSYCHIATRY

2015

Hematopoietic plakophilin-3 regulates acute tissue-specific and systemic inflammation in mice

Tatyana SklyarovaJolanda van HengelElien Van WonterghemClaude LibertFrans Van RoyRoosmarijn Vandenbroucke

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Mechanotransduction in cardiomyopathies : role of- and interaction between the areae compositae and extracellular matrix

Jolanda van HengelMarjolijn RenardJulie De Backer

The cardiac protein αT-catenin contributes to chemical-induced asthma

Stephen Sal FolmsbeeLuisa Morales-NebredaJolanda van HengelKoen TybergheinFrans Van RoyGR Scott BudingerPaul J BryceCara J Gottardi

A1 Journal Article in AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

2014

Alpha-catenins: protein replacement as a strategy against cancer invasion and metastasis?

Koen TybergheinFrans Van RoyJolanda van Hengel

Intercalated discs and arrhythmogenic cardiomyopathy

Alessandra RampazzoMartina CaloreJolanda van HengelFrans Van Roy

A1 Journal Article in CIRCULATION-CARDIOVASCULAR GENETICS

2013

Mutations in the area composita protein T-catenin are associated with arrhythmogenic right ventricular cardiomyopathy

Jolanda van HengelMartina CaloreBarbara BauceEmanuela DazzoElisa MazzottiMarzia De BortoliAlessandra LorenzonIlena EA Li MuraGiorgia BeffagnaIlaria Rigato et al.

A1 Journal Article in EUROPEAN HEART JOURNAL

N-cadherin is required for cytodifferentiation during zebrafish odontogenesis

Barbara VerstraetenJolanda van HengelEllen SandersFrans Van RoyAnn Huysseune

A1 Journal Article in JOURNAL OF DENTAL RESEARCH

2012

A radial glia-specific role of RhoA in double cortex formation

Silvia CappelloChristian RJ BöhringerMatteo BergamiKarl-Klaus ConzelmannAlexander GhanemGiulio Srubek TomassyPaola ArlottaMarco MainardiManuela AllegraMatteo Caleo et al.

A1 Journal Article in NEURON

Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells

Tim PietersLieven HaenebalckeTino HochepiedJinke D'HontJody HaighFrans Van RoyJolanda van Hengel

A1 Journal Article in STEM CELL REVIEWS AND REPORTS

Functions of p120ctn in development and disease

Tim PietersJolanda van HengelFrans Van Roy

A1 Journal Article in FRONTIERS IN BIOSCIENCE-LANDMARK

Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling

Tim PietersFrans Van RoyJolanda van Hengel

A1 Journal Article in FRONTIERS IN BIOSCIENCE-LANDMARK

Interaction of α-catulin with dystrobrevin contributes to integrity of dystrophin complex in muscle

Hyun J OhLinu S AbrahamJolanda van HengelChristophe StoveTomasz J ProszynskiKris GevaertJoseph X DiMarioJoshua R SanesFrans Van RoyHongkyun Kim

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia

Jifen LiSteven GoossensJolanda van HengelErhe GaoLan ChengKoen TybergheinXiying ShangRiet De RyckeFrans Van RoyGlenn L Radice

A1 Journal Article in JOURNAL OF CELL SCIENCE

Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis

Irina PleinesIna HagedornShuchi GuptaFrauke MayLidija ChakarovaJolanda van HengelStefan OffermannsGeorg KrohneChristoph KleinschnitzCord Brakebusch et al.

A1 Journal Article in BLOOD

Ocular anterior segment dysgenesis upon ablation of p120 catenin in neural crest cells

Huiyu TianEllen SandersAlbert ReynoldsFrans Van RoyJolanda van Hengel

A1 Journal Article in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

The cadherin-catenin complex during development and replacement of teeth in the zebrafish (Danio rerio)

Barbara VerstraetenAnn HuysseuneJolanda van Hengel

Tissue-wide overexpression of alpha-T-catenin results in aberrant trophoblast invasion but does not cause embryonic mortality in mice

Koen TybergheinSteven GoossensJody HaighFrans Van RoyJolanda van Hengel

A1 Journal Article in PLACENTA

2011

Effects of p120ctm knockout in Wnt1 expressing cells on skull growth in mouse

Emilie DescampsEllen SandersHuiyu TianJolanda van HengelFrans Van RoyDominique Adriaens

Functional analysis of mice harboring a knockout or knockin of the alternatively spliced exon C of p120ctn

Tim PietersFrans Van RoyJolanda van Hengel

RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

Ben JacksonKarine PeyrollierEsben PedersenAstrid BasseRichard KarlssonZhipeng WangTine LefeverAlexandra M OchsenbeinGudula SchmidtKlaus Aktories et al.

A1 Journal Article in MOLECULAR BIOLOGY OF THE CELL

The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool

Dominik HerzogPirmin LoetscherJolanda van HengelSebastian KnüselCord BrakebuschVerdon TaylorUeli SuterJoão B Relvas

A1 Journal Article in JOURNAL OF NEUROSCIENCE

2010

Expression pattern of E-cadherin during development of the first tooth in zebrafish (Danio rerio)

Barbara VerstraetenEllen SandersJolanda van HengelAnn Huysseune

A1 Journal Article in JOURNAL OF APPLIED ICHTHYOLOGY

Perturbations in the E-cadherin/catenin junctional complex in mouse embryos resulting in exencephaly

Emilie DescampsH TianEllen SandersJolanda van HengelFrans Van RoyDominique Adriaens

The cadherin-catenin complex and its importance in the development of brain and skull in mouse embryos

Emilie DescampsH TianE SandersJolanda van HengelFrans Van RoyDominique Adriaens

The transcriptional repressor Kaiso localizes at the mitotic spindle and is a constituent of the pericentriolar material

Adelheid SoubryKatrien StaesEef ParthoensSamuel NoppenChristophe StovePieter BogaertJolanda van HengelFrans Van Roy

A1 Journal Article in PLOS ONE

Zebrafish teeth as a model for repetitive epithelial morphogenesis: dynamics of E-cadherin expression

Barbara VerstraetenEllen SandersJolanda van HengelAnn Huysseune

A1 Journal Article in BMC DEVELOPMENTAL BIOLOGY

2009

Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes

J Van den BosschePieter BogaertJolanda van HengelChris GuerinGeert BerxK MovahediR Van den BerghA Pereira-FernandesJMC GeunsH Pircher et al.

A1 Journal Article in BLOOD

Exencephalic phenotype related to defects in the E-cadherin/catening complex in mouse embryos

Emilie DescampsHuiyu TianJolanda van HengelFrans Van RoyDominique Adriaens

2008

Continuous cell injury promotes hepatic tumorigenesis in Cdc42-deficient mouse liver

Jolanda van HengelPetra D'HoogeBart HoogheXunwei WuLouis LibbrechtRita De VosFabio QuondamatteoMartina KlemptCord BrakebuschFrans Van Roy

A1 Journal Article in GASTROENTEROLOGY

Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation

Tatyana SklyarovaStefan BonnéPetra D'HoogeGeertrui DeneckerSteven GoossensRiet De RyckeGaetan BorgonieMichael BöslFrans Van RoyJolanda van Hengel

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

alpha-Catulin, a Rho signalling component, can regulate NF-kappa B through binding to IKK-beta, and confers resistance to apoptosis

C WIESNERG WINSAUERU RESCHM HOETHJA SCHMIDJolanda van HengelFrans Van RoyBR BINDERR DE MARTIN

A1 Journal Article in ONCOGENE

2007

A unique and specific interaction between alpha T-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs

Steven GoossensBarbara JanssensStefan BonnéRiet De RyckeFilip BraetJolanda van HengelFrans Van Roy

A1 Journal Article in JOURNAL OF CELL SCIENCE

Diverse functions of p 20ctn in tumors

Jolanda van HengelFrans Van Roy

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

2005

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells

A CZUCHRAXW WUH MEYERJolanda van HengelT SCHROEDERR GEFFERSK ROTTNERC BRAKEBUSCH

A1 Journal Article in MOLECULAR BIOLOGY OF THE CELL

Expression and nuclear location of the transcriptional repressor kaiso is regulated by the tumor microenvironment

Adelheid SoubryJolanda van HengelEef ParthoensC COLPAERTE VAN MARCKD WALTREGNYAB REYNOLDSFrans Van Roy

A1 Journal Article in CANCER RESEARCH

Nuclear translocation of alpha N-catenin by the novel zinc finger transcriptional repressor ZASC1

Sven BogaertsAnn VanlandschootJolanda van HengelFrans Van Roy

A1 Journal Article in EXPERIMENTAL CELL RESEARCH

2004

Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness

Larissa KotelevetsJolanda van HengelErik BruyneelMarcus MareelFrans Van RoyE CHASTRE

A1 Journal Article in FASEB JOURNAL

alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease

V BUSBYSteven GoossensP NOWOTNYG HAMILTONS SMEMOD HAROLDD TURICL JEHUA MYERSM WOMICK et al.

A1 Journal Article in NEUROMOLECULAR MEDICINE

2003

Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy

Barbara JanssensB MOHAPATRAM VATTASteven GoossensGriet VanpouckePatrick KoolsTony MontoyeJolanda van HengelNE BOWLESFrans Van Roy et al.

A1 Journal Article in HUMAN GENETICS

2002

A novel role for p120 catenin in E-cadherin function.

RC IRETONMA DAVISJolanda van HengelDJ MARINERK BARNESMA THORESONPZ ANASTASIADISL MATRISIANLM BUNDYL SEALY et al.

A1 Journal Article in JOURNAL OF CELL BIOLOGY

Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells.

N MULLERA REINACHER-SCHICKS BALDUSJolanda van HengelGeert BerxA BAARFrans Van RoyW SCHMIEGELI SCHWARTE-WALDHOFF

A1 Journal Article in ONCOGENE

2001

The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness.

Larissa KotelevetsJolanda van HengelErik BruyneelMarcus MareelFrans Van RoyE CHASTRE

A1 Journal Article in JOURNAL OF CELL BIOLOGY

alpha T-Catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.

Barbara JanssensSteven GoossensK STAESB GILBERTJolanda van HengelC COLPAERTErik BruyneelMarcus MareelFrans Van Roy

A1 Journal Article in JOURNAL OF CELL SCIENCE

2000

Assignment of the plakophilin-9 gene (PKP2) and a plakophilin-2 pseudogene (PKP2P1) to human chromosome bands 12p11 and 12p13, respectively, by in situ hybridization.

Stefan BonnéJolanda van HengelFrans Van Roy

A1 Journal Article in CYTOGENETICS AND CELL GENETICS

The protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates p120 catenin.

H KEILHACKU HELLMANJolanda van HengelFrans Van RoyJ GODOVAC-ZIMMERMANNFD BOHMER

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

1999

Nuclear localization of the p120ctn Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression

Jolanda van HengelPeter VanhoenackerKatrien StaesFrans Van Roy

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plakophilin-3, a novel Armadillo-like protein present in nuclei and desmosomes of epithelial cells.

Stefan BonnéJolanda van HengelFriedel NolletPatrick KoolsFrans Van Roy

A1 Journal Article in JOURNAL OF CELL SCIENCE

1998

Chromosomal mapping of human armadillo genes belonging to the p120(ctn)/plakophilin subfamily.

Stefan BonnéJolanda van HengelFrans Van Roy

A1 Journal Article in GENOMICS

Cytoplasmic redistribution of E-cadherin-catenin adhesion complex is associated with down-regulated tyrosine phosphorylation of E-cadherin in human bronchopulmonary carcinomas.

B NAWROCKIM POLETTEJolanda van HengelJM TOURNIERFrans Van RoyP BIREMBAUT

A1 Journal Article in AMERICAN JOURNAL OF PATHOLOGY

Moleculaire analyse van intercellulaire juncties: studie van humane catenines en tumor-geassocieerde defecten

Jolanda van HengelF. Van Roy

Molecular cloning of the human p120(ctn) catenin gene (CTNND1): Expression of multiple alternatively spliced isoforms.

Annick KeirsebilckStefan BonnéK STAESJolanda van HengelFriedel NolletA REYNOLDSFrans Van Roy

A1 Journal Article in GENOMICS