Research Explorer

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Researcher

Jolanda van Hengel

101 Results

2022

Dielectric barrier discharge-treated aligned electrospun chitosan/polycaprolactone nanofibers for cardiac tissue engineering

Laurens LégerSheida AliakbarshiraziPegah ZahedifarNathalie De GeyterJeffrey AaldersRino MorentJolanda van HengelRouba Ghobeira

In vitro modelling of Marfan-related cardiomyopathy points to abnormalities in mechanobiology of the heart muscle cells

Jeffrey AaldersLaurens LégerLouis Van der MeerenPatrick SipsLaura Muiño MosqueraAndre SkirtachJulie De BackerJolanda van Hengel

In vitro modelling of Marfan-related cardiomyopathy points to abnormalities in mechanobiology of the heart muscle cells

Jeffrey AaldersLaurens LégerLouis Van der MeerenPatrick SipsLaura Muiño MosqueraAndre SkirtachJulie De BackerJolanda van Hengel

Microscopic visualization of cell-cell adhesion complexes at micro and nanoscale

Jolanda van Hengel

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Plakophilin3 loss leads to increased adenoma formation and rectal prolapse in APCmin mice

Jolanda van HengelFrans Van Roy

A1 Journal Article in BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

2021

Effects of fibrillin mutations on the behaviour of heart muscle cells in Marfan syndrome

Jeffrey AaldersLaurens LégerLouis Van der MeerenNatasja Van den VrekenAndre SkirtachJulie De BackerJolanda van Hengel

In vitro modelling of Marfan related cardiomyopathy points to abnormalities in mechanobiology of the heart muscle cells

Jeffrey AaldersLaurens LégerLouis Van der MeerenNatasja Van den VrekenAndre SkirtachJulie De BackerJolanda van Hengel

Liquid marbles: a cost-effective platform to generate cardiospheres from co-cultured cardiomyocytes and cardiac fibroblast for disease modelling

Jeffrey AaldersLaurens LégerJolanda van Hengel

Photothermal nanofibres enable safe engineering of therapeutic cells

Ranhua XiongDawei HuaJelter Van HoeckDominika BerdeckaLaurens LégerStijn De MunterJuan FraireLaurens RaesAranit HarizajFélix SauvageGlenn GoetgelukMelissa PilleJeffrey AaldersJoke BelzaThibaut Van AckerEduardo Bolea FernandezFrank VanhaeckeBart VandekerckhoveJolanda van HengelKoen RaemdonckStefaan De SmedtKevin Braeckmans

A1 Journal Article in NATURE NANOTECHNOLOGY

Use of transparent liquid marble : microbioreactor to culture cardiospheres

Jeffrey AaldersLaurens LégerJolanda van Hengel

Bookchapter in Next generation culture platforms for reliable in vitro models

2020

Effects of fibrillin mutations on the behavior of heart muscle cells in Marfan syndrome

Jeffrey AaldersLaurens LégerLouis Van der MeerenNatasja Van den VrekenAndre SkirtachJulie De BackerJolanda van Hengel

A1 Journal Article in SCIENTIFIC REPORTS

Exploring the three-dimensional organization of the murine intercalated disc and unraveling the connection between the intercalated disc and the cytoskeleton of cardiac myocytes

Bieke VanslembrouckJolanda van Hengel

Liquid marble technology to create cost-effective 3D cardiospheres as a platform for in vitro drug testing and disease modelling

Jeffrey AaldersLaurens LégerTim TuerlingsJolanda van Hengel

A2 Journal Article in METHODSX

Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice

Tim PietersEllen SandersHuiyu TianJolanda van HengelFrans Van Roy

A1 Journal Article in BMC DEVELOPMENTAL BIOLOGY

Time for rethinking the different β‐actin transgenic mouse models?

Bieke VanslembrouckChristophe AmpeJolanda van Hengel

A1 Journal Article in CYTOSKELETON

Unraveling the ultrastructural details of αT‐catenin‐deficient cell‐cell contacts between heart muscle cells by the use of FIB‐SEM

Bieke VanslembrouckAnna KremerFrans Van RoySaskia LippensJolanda van Hengel

A1 Journal Article in JOURNAL OF MICROSCOPY

2019

Armc8 is a evolutionarily conserved armadillo protein involved in cell-cell adhesion complexes through multiple molecular interactions

Ismail Sahin GülPaco HulpiauEllen SandersFrans Van RoyJolanda van Hengel

A1 Journal Article in BIOSCIENCE REPORTS

Cell communication in cardiac muscle cells

Jolanda van HengelJeffrey AaldersNatasja Van den VrekenMarleen De GrooteBieke Vanslembrouck

Closer look at heart cell connectors

Bieke VanslembrouckAnna KremerSaskia LippensJolanda van Hengel

Deletion of mucosa-associated lymphoid tissue lymphoma translocation protein 1 in mouse T cells protects against development of autoimmune arthritis but leads to spontaneous osteoporosis

Elisabeth GilisDjoere GaublommeJens StaalKoen VenkenMaarten DhaenensStijn LambrechtJulie CoudenysTine DecruyNadia SchryversYasmine DriegeEmilie DumasAnnelies DemeyerAmélie De MuynckJolanda van HengelLuc Van HoorebekeDieter DeforceRudi BeyaertDirk Elewaut

A1 Journal Article in ARTHRITIS & RHEUMATOLOGY

In vitro characterization of stem cell derived Marfan syndrome cardiomyocytes

Jeffrey AaldersLaurens LégerNatasja Van den VrekenJulie De BackerJolanda van Hengel

In vitro characterization of stem cell derived Marfan syndrome cardiomyocytes

Jeffrey AaldersLaurens LégerNatasja Van den VrekenJulie De BackerJolanda van Hengel

In vitro modelling of Marfan syndrome using stem cell derived cardiomyocytes

Jeffrey AaldersLaurens LégerNatasja Van den VrekenJulie De BackerJolanda van Hengel

Intercalated discs : specialized cytoskeletal anchors in cardiac muscle

Jolanda van HengelMaarten De SmetAnna KremerSaskia LippensMarjolijn RenardChristophe AmpeBieke Vanslembrouck

Modelling Marfan syndrome in vitro using human stem cell derived cardiomyocytes and fibroblasts

Jeffrey AaldersLaurens LégerNatasja Van den VrekenJulie De BackerJolanda van Hengel

Optimized protocol for the three-dimensional visualization and reconstruction of intercellular junctions in cardiac muscle using SBF-SEM and FIB-SEM

Bieke VanslembrouckAnna KremerBenjamin PavieFrans Van RoySaskia LippensJolanda van Hengel

Robust protocol for feeder-free adaptation of cryopreserved human pluripotent stem cells

Jeffrey AaldersNatasja Van den VrekenMina PopovicSwati MishraBjörn HeindryckxJolanda van Hengel

A1 Journal Article in IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Visualizing murine cardiac intercellular junctions and their links in 3D

Bieke VanslembrouckAnna KremerSaskia LippensJolanda van Hengel

2018

3-D reconstructions of intercellular junctions of the intercalated disc and their connection to complexes of the excitation-contraction coupling unit of cardiomyocytes

Bieke VanslembrouckAnna KremerBenjamin PavieFrans Van RoySaskia LippensJolanda van Hengel

A heart for fibrillin : spatial arrangement in adult wild-type murine myocardial tissue

Felke SteijnsJolanda van HengelPatrick SipsJulie De BackerMarjolijn Renard

A1 Journal Article in HISTOCHEMISTRY AND CELL BIOLOGY

Functional measurements of stem cell derived cardiomyocytes to model Marfan syndrome in vitro

Jeffrey AaldersNatasja Van den VrekenJulie De BackerJolanda van Hengel

Interactions between stem cell derived cardiomyocytes and extra cellular matrix to model Marfan syndrome in vitro

Jeffrey AaldersNatasja Van den VrekenJulie De BackerJolanda van Hengel

RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism

Jolanda van Hengel

A2 Journal Article in SMALL GTPASES

Robust protocol for feeder-free adaptation of frozen pluripotent stem cells using StemFlex

Jeffrey AaldersNatasja Van den VrekenBjörn HeindryckxJolanda van Hengel

Stem cell derived cardiomyocytes extra cellular matrix to model Marfan syndrome in vitro

Jeffrey AaldersNatasja Van den VrekenJulie De BackerJolanda van Hengel

Stem cell derived cardiomyocytes to model Marfan syndrome in vitro

Jeffrey AaldersNatasja Van den VrekenJulie De BackerJolanda van Hengel

Three-dimensional reconstruction of the intercalated disc including the intercellular junctions by applying volume scanning electron microscopy

Bieke VanslembrouckAnna KremerBenjamin PavieFrans Van RoySaskia LippensJolanda van Hengel

Three-dimensional reconstruction of the intercalated disc including the intercellular junctions by applying volume scanning electron microscopy

Bieke VanslembrouckAnna KremerFrans Van RoySaskia LippensJolanda van Hengel

A1 Journal Article in HISTOCHEMISTRY AND CELL BIOLOGY

2017

Cardiomyocyte cell junctions : unraveling the mechanobiology with 3-D volume electron microscopy

Bieke VanslembrouckMarjolijn RenardSaskia LippensAnna KremerJolanda van Hengel

FIB-SEM and SBF-SEM to unravel the cardiomyocyte cell junctions

Bieke VanslembrouckAnna KremerSaskia LippensMarjolijn RenardJolanda van Hengel

From pluripotent stem cells to cardiomyocytes

Jeffrey AaldersNatasja Van den VrekenJolanda van Hengel

Maturation of human pluripotent stem cell-derived cardiomyocytes

Jolanda van HengelNatasja Van den VrekenJeffrey Aalders

Structure-function studies in mouse embryonic stem cells using recombinase-mediated cassette exchange

Tim PietersLieven HaenebalckeKenneth BruneelNiels VandammeTino HochepiedJolanda van HengelGeert BerxFrans Van RoySteven Goossens

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

Ultra structure of the intercalated disc in murine cardiomyocard revealed by volume electron microscopy

Jolanda van HengelAnna KremerSaskia LippensBieke Vanslembrouck

2016

Beta-catenin and plakoglobin expression during zebrafish tooth development and replacement

Barbara VerstraetenJolanda van HengelAnn Huysseune

A1 Journal Article in PLOS ONE

Inactivation of p120 catenin in mice disturbs intrahepatic bile duct development and aggravates liver carcinogenesis

Jolanda van HengelCeline Van den BroekeTim PietersLouis LibbrechtFrans Van Roy

A1 Journal Article in EUROPEAN JOURNAL OF CELL BIOLOGY

Molecular evolution of the armadillo repeat superfamily and characterization of representative members in key model organisms

Ismail Sahin GülFrans Van RoyJolanda van Hengel

Ultra structure of the intercalated disc in murine cardiomyocard revealed by volume electron microscopy

Bieke VanslembrouckSteven Van WoenselAnna KremerSaskia LippensJolanda van Hengel

p120 Catenin-mediated stabilization of E-cadherin is essential for primitive endoderm specification

Tim PietersSteven GoossensLieven HaenebalckeVanessa AndriesRiet De RyckeKelly LemeireTino HochepiedGeert BerxJody HaighJolanda van HengelFrans Van Roy

A1 Journal Article in PLOS GENETICS

αT-catenin in restricted brain cell types and its potential connection to autism

Koen TybergheinPieter De BleserJolanda van HengelFrans Van Roy

A2 Journal Article in JOURNAL OF MOLECULAR PSYCHIATRY

2015

Hematopoietic plakophilin-3 regulates acute tissue-specific and systemic inflammation in mice

Tatyana SklyarovaJolanda van HengelElien Van WonterghemClaude LibertFrans Van RoyRoosmarijn Vandenbroucke

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Mechanotransduction in cardiomyopathies : role of- and interaction between the areae compositae and extracellular matrix

Jolanda van HengelMarjolijn RenardJulie De Backer

The cardiac protein αT-catenin contributes to chemical-induced asthma

Jolanda van HengelKoen TybergheinFrans Van Roy

A1 Journal Article in AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

2014

Alpha-catenins: protein replacement as a strategy against cancer invasion and metastasis?

Koen TybergheinFrans Van RoyJolanda van Hengel

Intercalated discs and arrhythmogenic cardiomyopathy

Jolanda van HengelFrans Van Roy

A1 Journal Article in CIRCULATION-CARDIOVASCULAR GENETICS

2013

Mutations in the area composita protein T-catenin are associated with arrhythmogenic right ventricular cardiomyopathy

Jolanda van HengelMara VleeschouwersKoen TybergheinPaco HulpiauEvelien Van HammeFrans Van Roy

A1 Journal Article in EUROPEAN HEART JOURNAL

N-cadherin is required for cytodifferentiation during zebrafish odontogenesis

Barbara VerstraetenJolanda van HengelEllen SandersFrans Van RoyAnn Huysseune

A1 Journal Article in JOURNAL OF DENTAL RESEARCH

2012

A radial glia-specific role of RhoA in double cortex formation

Jolanda van Hengel

A1 Journal Article in NEURON

Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells

Tim PietersLieven HaenebalckeTino HochepiedJinke D'HontJody HaighFrans Van RoyJolanda van Hengel

A1 Journal Article in STEM CELL REVIEWS AND REPORTS

Functions of p120ctn in development and disease

Tim PietersJolanda van HengelFrans Van Roy

A1 Journal Article in FRONTIERS IN BIOSCIENCE-LANDMARK

Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling

Tim PietersFrans Van RoyJolanda van Hengel

A1 Journal Article in FRONTIERS IN BIOSCIENCE-LANDMARK

Interaction of α-catulin with dystrobrevin contributes to integrity of dystrophin complex in muscle

Jolanda van HengelChristophe StoveKris GevaertFrans Van Roy

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia

Steven GoossensJolanda van HengelKoen TybergheinRiet De RyckeFrans Van Roy

A1 Journal Article in JOURNAL OF CELL SCIENCE

Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis

Jolanda van Hengel

A1 Journal Article in BLOOD

Ocular anterior segment dysgenesis upon ablation of p120 catenin in neural crest cells

Huiyu TianEllen SandersFrans Van RoyJolanda van Hengel

A1 Journal Article in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

The cadherin-catenin complex during development and replacement of teeth in the zebrafish (Danio rerio)

Barbara VerstraetenAnn HuysseuneJolanda van Hengel

Tissue-wide overexpression of alpha-T-catenin results in aberrant trophoblast invasion but does not cause embryonic mortality in mice

Koen TybergheinSteven GoossensJody HaighFrans Van RoyJolanda van Hengel

A1 Journal Article in PLACENTA

2011

Effects of p120ctm knockout in Wnt1 expressing cells on skull growth in mouse

Emilie DescampsEllen SandersHuiyu TianJolanda van HengelFrans Van RoyDominique Adriaens

Functional analysis of mice harboring a knockout or knockin of the alternatively spliced exon C of p120ctn

Tim PietersFrans Van RoyJolanda van Hengel

RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

Jolanda van Hengel

A1 Journal Article in MOLECULAR BIOLOGY OF THE CELL

The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool

Jolanda van Hengel

A1 Journal Article in JOURNAL OF NEUROSCIENCE

2010

Expression pattern of E-cadherin during development of the first tooth in zebrafish (Danio rerio)

Barbara VerstraetenEllen SandersJolanda van HengelAnn Huysseune

A1 Journal Article in JOURNAL OF APPLIED ICHTHYOLOGY

Perturbations in the E-cadherin/catenin junctional complex in mouse embryos resulting in exencephaly

Emilie DescampsEllen SandersJolanda van HengelFrans Van RoyDominique Adriaens

The cadherin-catenin complex and its importance in the development of brain and skull in mouse embryos

Emilie DescampsJolanda van HengelFrans Van RoyDominique Adriaens

The transcriptional repressor Kaiso localizes at the mitotic spindle and is a constituent of the pericentriolar material

Katrien StaesEef ParthoensSamuel NoppenChristophe StovePieter BogaertJolanda van HengelFrans Van Roy

A1 Journal Article in PLOS ONE

Zebrafish teeth as a model for repetitive epithelial morphogenesis: dynamics of E-cadherin expression

Barbara VerstraetenEllen SandersJolanda van HengelAnn Huysseune

A1 Journal Article in BMC DEVELOPMENTAL BIOLOGY

2009

Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes

Pieter BogaertJolanda van HengelChris GuerinGeert BerxJohan Grooten

A1 Journal Article in BLOOD

Exencephalic phenotype related to defects in the E-cadherin/catening complex in mouse embryos

Emilie DescampsHuiyu TianJolanda van HengelFrans Van RoyDominique Adriaens

2008

Continuous cell injury promotes hepatic tumorigenesis in Cdc42-deficient mouse liver

Jolanda van HengelPetra D'HoogeBart HoogheLouis LibbrechtFrans Van Roy

A1 Journal Article in GASTROENTEROLOGY

Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation

Tatyana SklyarovaStefan BonnéSteven GoossensRiet De RyckeGaetan BorgonieFrans Van RoyJolanda van Hengel

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

alpha-Catulin, a Rho signalling component, can regulate NF-kappa B through binding to IKK-beta, and confers resistance to apoptosis

Jolanda van HengelFrans Van Roy

A1 Journal Article in ONCOGENE

2007

A unique and specific interaction between alpha T-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs

Steven GoossensBarbara JanssensStefan BonnéRiet De RyckeFilip BraetJolanda van HengelFrans Van Roy

A1 Journal Article in JOURNAL OF CELL SCIENCE

Diverse functions of p 20ctn in tumors

Jolanda van HengelFrans Van Roy

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

2005

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells

Jolanda van Hengel

A1 Journal Article in MOLECULAR BIOLOGY OF THE CELL

Expression and nuclear location of the transcriptional repressor kaiso is regulated by the tumor microenvironment

Adelheid SoubryJolanda van HengelEef ParthoensFrans Van Roy

A1 Journal Article in CANCER RESEARCH

Nuclear translocation of alpha N-catenin by the novel zinc finger transcriptional repressor ZASC1

Sven BogaertsAnn VanlandschootJolanda van HengelFrans Van Roy

A1 Journal Article in EXPERIMENTAL CELL RESEARCH

2004

Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness

Larissa KotelevetsJolanda van HengelErik BruyneelMarcus MareelFrans Van Roy

A1 Journal Article in FASEB JOURNAL

alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease

Steven GoossensBarbara JanssensJolanda van HengelFrans Van Roy

A1 Journal Article in NEUROMOLECULAR MEDICINE

2003

Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy

Barbara JanssensSteven GoossensGriet VanpouckePatrick KoolsTony MontoyeJolanda van HengelFrans Van Roy

A1 Journal Article in HUMAN GENETICS

2002

A novel role for p120 catenin in E-cadherin function.

Jolanda van HengelFrans Van Roy

A1 Journal Article in JOURNAL OF CELL BIOLOGY

Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells.

Jolanda van HengelGeert BerxFrans Van Roy

A1 Journal Article in ONCOGENE

2001

The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness.

Larissa KotelevetsJolanda van HengelErik BruyneelMarcus MareelFrans Van Roy

A1 Journal Article in JOURNAL OF CELL BIOLOGY

alpha T-Catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.

Barbara JanssensSteven GoossensJolanda van HengelErik BruyneelMarcus MareelFrans Van Roy

A1 Journal Article in JOURNAL OF CELL SCIENCE

2000

Assignment of the plakophilin-9 gene (PKP2) and a plakophilin-2 pseudogene (PKP2P1) to human chromosome bands 12p11 and 12p13, respectively, by in situ hybridization.

Stefan BonnéJolanda van HengelFrans Van Roy

A1 Journal Article in CYTOGENETICS AND CELL GENETICS

The protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates p120 catenin.

Jolanda van HengelFrans Van Roy

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

1999

Nuclear localization of the p120ctn Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression

Jolanda van HengelPeter VanhoenackerKatrien StaesFrans Van Roy

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plakophilin-3, a novel Armadillo-like protein present in nuclei and desmosomes of epithelial cells.

Stefan BonnéJolanda van HengelFriedel NolletPatrick KoolsFrans Van Roy

A1 Journal Article in JOURNAL OF CELL SCIENCE

1998

Chromosomal mapping of human armadillo genes belonging to the p120(ctn)/plakophilin subfamily.

Stefan BonnéJolanda van HengelFrans Van Roy

A1 Journal Article in GENOMICS

Cytoplasmic redistribution of E-cadherin-catenin adhesion complex is associated with down-regulated tyrosine phosphorylation of E-cadherin in human bronchopulmonary carcinomas.

Jolanda van HengelFrans Van Roy

A1 Journal Article in AMERICAN JOURNAL OF PATHOLOGY

Moleculaire analyse van intercellulaire juncties: studie van humane catenines en tumor-geassocieerde defecten

Jolanda van Hengel

Molecular cloning of the human p120(ctn) catenin gene (CTNND1): Expression of multiple alternatively spliced isoforms.

Annick KeirsebilckStefan BonnéJolanda van HengelFriedel NolletFrans Van Roy

A1 Journal Article in GENOMICS