Research Explorer

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Researcher

Johan Van der Eycken

Awards & Distinctions

136 Results

2024

Pelophen B is a non-taxoid binding microtubule-stabilizing agent with promising preclinical anticancer properties

Stephanie VermeulenSam ErnstEva BlondeelZihan XiaPekka RappuJyrki HeinoSandor DedeyneHannelore DenysGwen SysStefanie Gijsels et al.

A1 Journal Article in SCIENTIFIC REPORTS

2023

D-Quinic acid-derived cyclitol-α-amino acids as building blocks for novel hydrophilic foldamers, aminocyclitols and spiro-1,4-benzodiazepines with potential biological activity

Bo Van de MoortelJohan Van der Eycken

Molecular mechanisms of nemorosone-induced ferroptosis in cancer cells

Roberto Fernández-AcostaBehrouz HassanniaJurgen CaroenBartosz WiernickiDaniel Alvarez-AlminaqueBruno VerstraetenJohan Van der EyckenPeter VandenabeeleTom Vanden BergheGilberto L. Pardo-Andreu

A1 Journal Article in CELLS

Trehalose-6-phosphate signaling regulates lateral root formation in Arabidopsis thaliana

Stefania MoralesJoris JourquinFrederic CoppéLorena Lopez GalvisTom De SmetAlaeddine SafiMaria NjoCara A. GriffithsJohn D. SiddaJames S. O. Mccullagh et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2022

Late-stage diversification of peptidomimetics and oligopeptides via gold-catalyzed post-Ugi cyclization

Liangliang SongChao LiuGuilong TianLuc Van MeerveltJohan Van der EyckenErik V. Van der Eycken

A1 Journal Article in MOLECULAR CATALYSIS

Pd-catalyzed ring restructuring of oxazolidines with alkenes leading to fused polycyclic indolizines

Xianjun XuHuangdi FengXiaoyong ZhangLiangliang SongLuc Van MeerveltJohan Van der EyckenJeremy N. HarveyErik V. Van der Eycken

A1 Journal Article in ORGANIC LETTERS

Sweet biotechnology : enzymatic production and digestibility screening of novel kojibiose and nigerose analogues

Shari DhaeneAmar Daniël Emanuel Van LaarMarc De DonckerEmma De BeulKoen BeerensCharlotte GrootaertJurgen CaroenJohan Van der EyckenJohn Van CampTom Desmet

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

2021

Chemoselective peptide backbone diversification and bioorthogonal ligation by ruthenium-catalyzed C-H activation/annulation

Liangliang SongGerardo M. Ojeda-CarraleroDivyaakshar ParmarDavid A. Gonzalez-MartinezLuc Van MeerveltJohan Van der EyckenJan GoemanDaniel G. RiveraErik V. Van der Eycken

A1 Journal Article in ADVANCED SYNTHESIS & CATALYSIS

Synthesis and testing of novel chiral biferrocene-based ligands for asymmetric transition metal catalysis

Wim KimpeJohan Van der EyckenTimothy Noël

2020

Ruthenium-catalyzed cascade C-H activation/annulation of N-alkoxybenzamides : reaction development and mechanistic insight

Liangliang SongXiaoyong ZhangXiao TangLuc Van MeerveltJohan Van der EyckenJeremy N. HarveyErik V. Van der Eycken

A1 Journal Article in CHEMICAL SCIENCE

Synthesis, trehalase hydrolytic resistance and inhibition properties of 4-and 6-substituted trehalose derivatives

Shari DhaeneJohan Van der EyckenKoen BeerensJorick FranceusTom DesmetJurgen Caroen

A1 Journal Article in JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

2019

4''-O-Alkylated α-galactosylceramide analogues as iNKT-cell antigens : synthetic, biological, and structural studies

Jonas JanssensAruna BitraJing WangTine DecruyKoen VenkenJohan Van der EyckenDirk ElewautDirk ZajoncSerge Van Calenbergh

A1 Journal Article in CHEMMEDCHEM

Ceramide-templated macrolactams : total synthesis and biological evaluation of macrocyclic α-galactosylceramide analogues and their aglycons

Jonas JanssensJohan Van der EyckenSerge Van Calenbergh

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Intramolecular cascade annulation triggered by rhodium(III)-catalyzed sequential C(sp²) H activation and C(sp³)-H amination

Liangliang SongGuilong TianJohan Van der EyckenErik V Van der Eycken

A1 Journal Article in BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY

New fluoroethyl phenylalanine analogues as potential LAT1-targeting PET tracers for glioblastoma

Jeroen VerhoevenFabian HulpiaKen KersemansJulie BolcaenStef De LombaerdeJan GoemanBenedicte DescampsGiorgio HallaertCaroline Van den BroeckeKarel Deblaere et al.

A1 Journal Article in SCIENTIFIC REPORTS

Novel biferrocene-based phosphoramidite ligands : the combination of a rather unexplored chiral backbone and a privileged ligand scaffold

Wim KimpePieter JanssensKatrien BertSam WackensJan GoemanJohan Van der Eycken

A1 Journal Article in TETRAHEDRON

Rational design of an improved transglucosylase for production of the rare sugar nigerose

Jorick FranceusShari DhaeneHannes DecadtJudith VandepitteJurgen CaroenJohan Van der EyckenKoen BeerensTom Desmet

A1 Journal Article in CHEMICAL COMMUNICATIONS

α-Galactosylceramide analogues as iNKT-cell antigens : synthesis, biological evaluation and structural analysis

Jonas JanssensJohan Van der EyckenSerge Van Calenbergh

2018

4"-O-alkylated α-galactosylceramide analogues as iNKT cell antigens : synthetic, biological and structural studies

Jonas JanssensJing WangAruna BitraTine DecruyKoen VenkenJohan Van der EyckenDirk ElewautDirk ZajoncSerge Van Calenbergh

One-pot synthesis and photophysical studies of dihydropyrimidinone-based dyes : novel violet-blue light emitting fluorophores

Akanksha MattaMohit GuptaYogesh KumarToshiaki TaniikeJohan Van der EyckenBrajendra K Singh

A1 Journal Article in CHEMISTRYSELECT

Regioselective ring opening of 1,3-dioxane-type acetals in carbohydrates

Jonas JanssensMartijn RisseeuwJohan Van der EyckenSerge Van Calenbergh

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

2017

Daucane esters from laserwort (Laserpitium latifolium L.) inhibit cytokine and chemokine production in human lung epithelial cells

Visnja PopovicJan GoemanJonathan ThommisArne HeyerickJurgen CaroenJohan Van der EyckenKarolien De Bosscher

A1 Journal Article in PHYTOMEDICINE

Efficient divergent synthesis of new immunostimulant 4″-modified α-galactosylceramide analogues

Jonas JanssensTine DecruyKoen VenkenToshiyuki SekiSimon KrolsJohan Van der EyckenMoriya TsujiDirk ElewautSerge Van Calenbergh

A1 Journal Article in ACS MEDICINAL CHEMISTRY LETTERS

Involvement of the glucocorticoid receptor in pro-inflammatory transcription factor inhibition by daucane esters from Laserpitium zernyi

Visnja PopovicJan GoemanNadia BougarneSven EyckermanArne HeyerickKarolien De BosscherJohan Van der Eycken

A1 Journal Article in JOURNAL OF NATURAL PRODUCTS

Solid-phase synthesis of compound libraries around the 1,5-benzodiazocine-2,6-dione privileged structure-like scaffold

Heba ElmetwallyJohan Van der Eycken

Synthesis and evaluation of imidate-based ligands for asymmetric transition metal catalysis

Pieter JanssensJohan Van der Eycken

Synthesis, characterisation and photophysical studies of oxadiazolyl coumarin : a new class of blue light emitting fluorescent dyes

Akanksha MattaVijay BahadurToshiaki TaniikeJohan Van der EyckenBrajendra K Singh

A1 Journal Article in DYES AND PIGMENTS

Towards the synthesis of analogs of (+)-peloruside A, a natural product with promising biological properties

Dries Van den BosscheJohan Van der Eycken

2016

A PMB-protecting group strategy for the divergent synthesis of 4”-modified alpha-galactosylceramide analogues

Jonas JanssensJohan Van der EyckenSerge Van Calenbergh

A practical approach to the synthesis of new 4”-modified α-galactosylceramide analogues

Jonas JanssensJohan Van der EyckenSerge Van Calenbergh

Atomic layer deposition of Pt nanoparticles within the cages of MIL-101 : a mild and recyclable hydrogenation catalyst

Karen LeusJolien DendoovenNorini TahirRanjith Karuparambil RamachandranMaria MeledinaStuart TurnerGustaaf Van TendelooJan GoemanJohan Van der EyckenChristophe Detavernier et al.

A1 Journal Article in NANOMATERIALS

Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents

Lijun SongMartijn RisseeuwMatheus FroeyenIzet KaralicJan GoemanDavie CappoenJohan Van der EyckenPaul CosHélène Munier-LehmannSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Mimicking 1,5-benzodiazepine-2,4-diones, a modular approach on solid-phase

Fréderique BackaertJohan Van der Eycken

Solid phase synthesis of structurally diverse 1,2,5-benzothiadiazepin-4-one-1,1-dioxides, 1,2,5-thiadiazepin-4-one-1,1-dioxides and 1,2,6-benzothiadiazocin-5-one-1,1-dioxides

Karel-Simon SlockJohan Van der Eycken

Solid-phase synthesis of 6,7-cycloalkane-fused 1,4-diazepane-2,5-diones via a cyclization/release strategy

Jurgen CaroenAn ClemmenJudit KámánFréderique BackaertJan GoemanFerenc FülöpJohan Van der Eycken

A1 Journal Article in TETRAHEDRON

Synthesis and biological evaluation of phytosphingosine modified α-GalCer analogues as potential immunomodulating agents

Jonas JanssensJohan Van der EyckenSerge Van Calenbergh

2015

Gold- and silver-catalyzed 7-endo-dig cyclizations for the synthesis of oxazepines

Anatoly A PeshkovAnton A NechaevOlga P PereshivkoJan L GoemanJohan Van der EyckenVsevolod A PeshkovErik V Van der Eycken

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

In vitro prediction of human intestinal absorption and blood-brain barrier partitioning: development of a lipid analog for micellar liquid chromatography

Mike De VriezePieter JanssensRoman SzucsJohan Van der EyckenFrederic Lynen

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Novel anti-inflammatory daucane esters from Laserpitium zernyi Hayek (Apiaceae)

Visnja PopovicJan GoemanNadia BougarneArne HeyerickKarolien De BosscherJohan Van der Eycken

Study of the chemoselectivity of multicomponent heterocyclizations involving 3-amino-1,2,4-triazole and pyruvic acids as key reagents, and biological activity of the reaction products

Maryna V MurlykinaYana I SakhnoSergey M DesenkoSvetlana V ShishkinaOleg V ShishkinDmytro O SysoievMaryna N KornetDominique ScholsJan GoemanJohan Van der Eycken et al.

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Supported gold nanoparticles as efficient and reusable heterogeneous catalyst for cycloisomerization reactions

Felix SchröderManuel OjedaNico ErdmannJeroen JacobsRafael LuqueTimothy NoëlLuc Van MeerveltJohan Van der EyckenErik V Van der Eycken

A1 Journal Article in GREEN CHEMISTRY

Synthese en valorisatie van imidaatgebaseerde liganden voor transitiemetaalkatalyse

Katrien BertJohan Van der Eycken

Synthesis of a phosphocholine based lipid for improved micellar LC based in vitro predictions of human intestinal absorption and blood-brain barrier partitioning

Mike De VriezePieter JanssensRoman SzucsJohan Van der EyckenFrederic Lynen

Towards the total synthesis of peloruside A and side‐chain analogues

Sam PietersJohan Van der Eycken

2014

Cyclitol-alpha-amino acids as building blocks in new hydrophilic foldamers

Bo Van de MoortelT MaesJurgen CaroenJan GoemanJohan Van der Eycken

Sesquiterpenes from selected Laserpitium L. species as antimicrobial agents

Visnja PopovicDejan StojkovicMilos NikolicNadia BougarneJan GoemanArne HeyerickKarolien De BosscherMarina SokovicJohan Van der Eycken

2013

Ferrocene-derived P,N ligands : synthesis and application in enantioselective catalysis

Timothy NoëlJohan Van der Eycken

A1 Journal Article in GREEN PROCESSING AND SYNTHESIS

Synthesis of the natural product building block 5-(3-bromophenyl)-4-hydroxy-5-methylhexan-2-one and its chiral characterization by using chiroptical spectroscopy

Ewoud De GussemJelle CornelusSam PietersDries Van den BosscheJohan Van der EyckenWouter HerreboutPatrick Bultinck

A1 Journal Article in CHEMPHYSCHEM

2012

Chiral imidate ligands : synthesis and applications in asymmetric catalysis

Timothy NoëlKatrien BertPieter JanssensJohan Van der Eycken

Bookchapter in Innovative catalysis in organic synthesis : oxidation, hydrogenation, and C-X bond forming reactions

Chiral imidate-ferrocenylphosphanes: synthesis and application as P,N-ligands in iridium(I)-catalyzed hydrogenation of unfunctionalized and poorly functionalized olefins

Katrien BertTimothy NoëlWim KimpeJan GoemanJohan Van der Eycken

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

Deposition of photocatalytically active TiO2 films by inkjet printing of TiO2 nanoparticle suspensions obtained from microwave-assisted hydrothermal synthesis

Melis ArinPetra LommensSimon C HopkinsGlenn PollefeytJohan Van der EyckenSusagna RicartXavier GranadosBartek A GlowackiIsabel Van Driessche

A1 Journal Article in NANOTECHNOLOGY

Novel method for simultaneous determination of p-cresylsulphate and p-cresylglucuronide: clinical data and pathophysiological implications

Natalie MeertEva SchepersGriet GlorieuxMaria Van LandschootJan GoemanMARIA WATERLOOSAnnemieke DhondtJohan Van der EyckenRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential

Simone EspositoKoen DeventerJan GoemanJohan Van der EyckenPeter Van Eenoo

A1 Journal Article in DRUG TESTING AND ANALYSIS

Synthesis of a novel C2-symmetric bis-oxazoline (_bis[4,5-dihydrooxazole]) and its application as chiral ligand in asymmetric transition metal catalysis

Yaşar GökJohan Van der Eycken

A1 Journal Article in HELVETICA CHIMICA ACTA

2011

De enantioselectieve Heck-reactie: valorisatie van huisbereide liganden en de vergelijking met enkele 'vaste waarden'

Simon CogenJohan Van der Eycken

Synthese van aza-gemodificeerde analogen van simmondsine met potentiële anti-angiogenese-activiteit

Ine De VilderJohan Van der Eycken

2010

A novel C2-symmetric bisphosphane ligand with a chiral cyclopropane backbone: synthesis and application in the Rh(I)-catalyzed asymmetric 1,4-addition of arylboronic acids

Yasar GökTimothy NoëlJohan Van der Eycken

A1 Journal Article in TETRAHEDRON-ASYMMETRY

Imidate-phosphanes as highly versatile N,P ligands and their application in palladium-catalyzed asymmetric allylic alkylation reactions

Timothy NoëlKatrien BertErik Van der EyckenJohan Van der Eycken

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Novel C2-symmetric bisoxazolines with a chiral trans-(2R,3R)-diphenylcyclopropane backbone: preparation and application in several enantioselective catalytic reactions

Yasar GökTimothy NoëlJohan Van der Eycken

A1 Journal Article in TETRAHEDRON-ASYMMETRY

Rhodium/olefin-catalyzed reaction of arylboronic acids with an α-acetamido acrylic ester: Mizoroki-Heck-type reaction versus asymmetric conjugate addition

Timothy NoëlYasar GökJohan Van der Eycken

A1 Journal Article in TETRAHEDRON-ASYMMETRY

trans-(2R,3R)-2,3-Diphenylcyclopropane-1,1-dimethanol: a pivotal diol for the synthesis of novel C(2)-symmetric ligands for asymmetric transition metal catalysis

Elias VerveckenMichel Van OverscheldeTimothy NoëlYasar GökSusana Alvárez RodríguezSimon CogenJohan Van der Eycken

A1 Journal Article in TETRAHEDRON-ASYMMETRY

2009

A sensitive and practical colorimetric test for polymer-supported hydroxyl and thiol groups

Jurgen CaroenJohan Van der Eycken

A1 Journal Article in TETRAHEDRON LETTERS

An asymmetric approach towards (-)-aphanorphine and its analogues

Pavel A DonetsJan GoemanJohan Van der EyckenKoen RobeynsLuc Van MeerveltErik V Van der Eycken

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Catalyst-free alcoholysis of phosphane-boranes: a smooth, cheap, and efficient deprotection procedure

Michel Van OverscheldeElias VerveckenSachin G ModhaSimon CogenErik Van der EyckenJohan Van der Eycken

A1 Journal Article in TETRAHEDRON

Chiral imidates as a new class of nitrogen-based chiral ligands: synthesis and catalytic activity in asymmetric aziridinations and diethylzinc additions

Timothy NoëlKoen VandyckKoen RobeynsLuc Van MeerveltJohan Van der Eycken

A1 Journal Article in Tetrahedron

Efficient one-step synthesis of chiral bidentate oxazoline-alcohol ligands

Timothy NoëlKoen RobeynsLuc Van MeerveltErik Van der EyckenJohan Van der Eycken

A1 Journal Article in Tetrahedron: Asymmetry

Synthesis and application of chiral dienes and chiral imidates as ligands for transition metal catalysis

Timothy NoëlJohan Van der Eycken

2008

Synthesis of isofagomine and a new C-6 pyrrolidine azasugar with potential biological activity

Pieter EspeelKathleen PiensNico CallewaertJohan Van der Eycken

A1 Journal Article in SYNLETT

2007

A DFT conformational analysis and VCD study on methyl tetrahydrofuran-2-carboxylate

Tom KuppensKoen VandyckJohan Van der EyckenW HERREBOUTBert Van der VekenPatrick Bultinck

A1 Journal Article in SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Carbohydrate-based macrolides prepared via a convergent ring closing metathesis approach: In search for novel antibiotics

Bart RuttensP BLOMSteven Van HoofIdzi HubrechtJohan Van der Eycken

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Divergent strategy for the synthesis of α-aryl-substituted fosmidomycin analogues

Vincent DevreuxJochen WiesnerHassan JomaaJef RozenskiJohan Van der EyckenSerge Van Calenbergh

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

P-cresylsulphate, the main in vivo metabolite of p-cresol, activates leucocyte free radical production

Eva SchepersNatalie MeertGriet GlorieuxJan GoemanJohan Van der EyckenRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Some new C-2-symmetric bicyclo[2.2.1]heptadiene ligands: synthesis and catalytic activity in rhodium(I)-catalyzed asymmetric 1,4-and 1,2-additions

Timothy NoëlKoen VandyckJohan Van der Eycken

A1 Journal Article in TETRAHEDRON

Synthesis and evaluation of α,β-unsaturated α-aryl-substituted fosmidomycin analogues as DXR inhibitors

Vincent DevreuxJochen WiesnerHassan JomaaJohan Van der EyckenSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Transition metal-catalyzed orthogonal solid-phase decoration of the 2(1H)-pyrazinone scaffold using a sulfur linker

N KAVALBK SINGHDS ERMOLAT'EVS CLAERHOUTVS PARMARJohan Van der EyckenE VAN DER EYCKEN

A1 Journal Article in JOURNAL OF COMBINATORIAL CHEMISTRY

2006

Rhodium-catalyzed asymmetric conjugate additions of boronic acids to enones using DIPHONANE: A novel chiral bisphosphine ligand

Koen VandyckBavo MatthysM WILLENK ROBEYNSL VAN MEERVELTJohan Van der Eycken

A1 Journal Article in ORGANIC LETTERS

Synthesis and biological evaluation of cyclopropyl analogues of fosmidomycin as potent Plasmodium falciparum growth inhibitors

Vincent DevreuxJochen WiesnerJan GoemanJohan Van der EyckenHassan JomaaSerge Van Calenbergh

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and screening of bicyclic carbohydrate-based compounds: A novel type of antivirals

Steven Van HoofBart RuttensIdzi HubrechtGert SmansP BLOMBenedikt SasJ VAN HEMELJ VANDENKERCKHOVEJohan Van der Eycken

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Vibrational circular dichroism DFT study on bicyclo[3.3.0]octane derivatives

Elke DebieTom KuppensKoen VandyckJohan Van der EyckenBert Van der VekenW HERREBOUTPatrick Bultinck

A1 Journal Article in TETRAHEDRON-ASYMMETRY

2005

A convergent ring-closing metathesis approach to carbohydrate-based macrolides with potential antibiotic activity

P BLOMBart RuttensSteven Van HoofIdzi HubrechtJohan Van der EyckenBenedikt SasJ VAN HEMELJ VANDENKERCKHOVE

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

An efficient microwave-assisted solvent-free synthesis of pyrido-fused ring systems applying the tert-amino effect

N KAVALB HALASZ-DAJKAG VO-THANHW DEHAENJohan Van der EyckenP MATYUSA LOUPYE VAN DER EYCKEN

A1 Journal Article in TETRAHEDRON

Determination of the absolute configuration of three as-hydrindacene compounds by vibrational circular dichroism

Tom KuppensKoen VandyckJohan Van der EyckenW HERREBOUTBJ VAN DER VEKENPatrick Bultinck

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Synthesis and absolute configuration of (1S,8S)-as-hydrindacene-1,8-diol as determined by the circular dichroism exciton chirality method

K VANDYCKBavo MatthysJohan Van der Eycken

A1 Journal Article in TETRAHEDRON LETTERS

Synthesis of new 3,3-dimethoxyazetidine-2-carboxylic acid derivatives

Sven MangelinckxMarc BoeykensM VLIEGENJohan Van der EyckenNorbert De Kimpe

A1 Journal Article in TETRAHEDRON LETTERS

2004

Distribution of soy-derived phytoestrogens in human breast tissue and biological fluids

J MAUBACHHerman DepypereJan GoemanJohan Van der EyckenArne Heyerickmarc brackePhillip BlondeelDenis De Keukeleire

A1 Journal Article in OBSTETRICS AND GYNECOLOGY

Generation of a small library of highly electron-rich 2-(Hetero)aryl-substituted phenethylamines by the Suzuki-Miyaura reaction: A short synthesis of an apogalanthamine analogue

P APPUKKUTTANAB ORTSRP CHANDRANJan GoemanJohan Van der EyckenW D'EHAENE VAN DER EYCKEN

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Phenolic profiling of caffeic acid O-methyltransferase-deficient poplar reveals novel benzodioxane oligolignols

Kris MorreelJohn RalphFachuang Lu LuGeert GoeminneRoger BussonPiet HerdewijnJan GoemanJohan Van der EyckenWout BoerjanEric Messens

A1 Journal Article in PLANT PHYSIOLOGY

Synthesis of alicyclic beta-lactams via the ugi reaction on a solid support

S GEDEYJohan Van der EyckenF FULOP

A1 Journal Article in LETTERS IN ORGANIC CHEMISTRY

2003

An exploratory study on microwave-assisted solid-phase Diels-Alder reactions of 2(1H)-pyrazinones: the elaboration of a new tailor-made acid-labile linker

N KAVALJohan Van der EyckenJurgen CaroenW DEHAENGA STROHMEIERCO KAPPEE VAN DER EYCKEN

A1 Journal Article in JOURNAL OF COMBINATORIAL CHEMISTRY

2002

D-Isomannide in synthesis: asymmetric Diels-Alder reactions with novel homochiral bis-imine Cu2+-catalysts.

Gert De CosterK VANDYCKE VAN DER EYCKENJohan Van der EyckenM ELSEVIERSH ROPER

A1 Journal Article in TETRAHEDRON-ASYMMETRY

Liquid-phase combinatorial synthesis of alicyclic beta-lactams via Ugi four-component reaction.

S GEDEYJohan Van der EyckenF FULOP

A1 Journal Article in ORGANIC LETTERS

Solid-phase synthesis of a new class of oligosaccharide analogues based on azasugars.

Bart RuttensJohan Van der Eycken

A1 Journal Article in TETRAHEDRON LETTERS

2001

Alkyl-lysophospholipid 1-O-octadecyl-2-O-methyl-glycerophosphocholine induces invasion through epislalin-mediated neutralization of E-cadherin in human mammary MCF-7 cells in vitro.

Wim SteelantJL GOEMANJan PhilippéL OOMENJ HILKENSMA KRZEWINSKI-RECCHIG HUETJohan Van der EyckenP DELANNOYErik Bruyneel et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Enzymatic resolution of bicyclic 1,3-amino alcohols in organic media.

Judit KamanJohan Van der EyckenA PETERF FULOP

A1 Journal Article in TETRAHEDRON-ASYMMETRY

High-performance liquid chromatographic enantioseparation of bicyclic 1,3-amino alcohols.

A PETERJudit KamanF FULOPJohan Van der EyckenDW ARMSTRONG

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Synthesis of (1S)-1-amino-2,2-dimethylcyclopropane-1-carboxylic acid via PLE mediated hydrolysis of bis (2,2,2-trifluoroethyl) 2,2-dimethylcyclopropane-1,1-dicarboxylate.

A SALGADOTom HuybrechtsA EECKHAUTJohan Van der EyckenZ SZAKONYIF FULOPA TKACHEVNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Synthesis of C-11-labelled acamprosate for PET studies

Jan CourtynPatrick GoethalsJohan Van der EyckenRichard Dams

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

2000

Applicability of the alkylation chemistry for chemical C-terminal protein sequence analysis.

Bart SamynKlaas HardemanJohan Van der EyckenJozef Van Beeumen

A1 Journal Article in ANALYTICAL CHEMISTRY

Sudan-β-D-glucuronides and their use for the histochemical localization of β-glucuronidase activity in transgenic plants

Erik Van der EyckenNancy TerrynJL GoemanGunter CarlensWim NerinckxMarc ClaeyssensJohan Van der EyckenMarc Van MontaguM Brito-AriasGilbert Engler

A1 Journal Article in PLANT CELL REPORTS

Synthesis of 6a-Carba-alpha- and 6a-Carba-beta-d-fructopyranose from an enzymatically resolved cyclohexanetriol building block.

Idzi HubrechtE VAN DER EYCKENJohan Van der Eycken

A1 Journal Article in SYNLETT

1999

Chiral discrimination of cyclic 1,3-amino alcohol enantiomers.

M PETERG BERNATHF FULOPJohan Van der Eycken

A1 Journal Article in MAGYAR KEMIAI FOLYOIRAT

1998

An improved chemical approach toward the C-terminal sequence analysis of proteins containing all natural amino acids

Klaas HardemanBart SamynJohan Van der EyckenJozef Van Beeumen

A1 Journal Article in PROTEIN SCIENCE

Enzymatic resolution of alicyclic 1,3-amino alcohols in organic media.

M PETERJohan Van der EyckenG BERNATHF FULOP

A1 Journal Article in TETRAHEDRON-ASYMMETRY

High-performance liquid chromatographic separation of enantiomers of cyclic 1,3-amino alcohol derivatives

Maria PeterAntal PeterJohan Van der EyckenPeter CsomosGabor BernathFerenc Fulop

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Sodium tetra(n-propyl)borate : a novel aqueous in situ derivatization reagent for the simultaneous determination of organomercury, -lead and -tin compounds with capillary gas chromatography inductively coupled plasma mass spectrometry

Tom De SmaeleLuc MoensRichard DamsPatrick SandraJohan Van der EyckenJos Vandyck

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Synthesis of L-xylo-hexos-2-ulose (L-sorbosone) and its characterisation by chromatographic and spectroscopic techniques

Erik Van der EyckenGunter CarlensJ MessensYining ZhaoGuy BauwJohan Van der EyckenPatrick SandraMarc Van Montagu

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

1995

Stereochemical features of meta photocycloadducts derived from 3-alkyl-4-phenoxybut-1-enes

Erik Van der EyckenDenis De KeukeleireAndré De BruynJohan Van der EyckenA Gilbert

A1 Journal Article in RECUEIL DES TRAVAUX CHIMIQUES DES PAYS-BAS-JOURNAL OF THE ROYAL NETHERLANDS CHEMICAL SOCIETY

1994

Enantioselective separations by capillary GC on derivatized cyclodextrins : 2. Determination of the enantiomeric excess of some racemic 2,3-isopropylidene-1,2,3-cyclohexanetriol derivatives on permethyl α-, β-, and γ-cyclodextrins

Kristian JaquesW BudaL DumortierJohan Van der EyckenArnold VenemaPatrick Sandra

A1 Journal Article in HRC-JOURNAL OF HIGH RESOLUTION CHROMATOGRAPHY

Enantioselective separations by capillary GC on derivatized cyclodextrins : part 1 : separation of some racemic 2,2-dialkyl-4-alkoxycarbonyl-1,3-dioxolane derivatives on permethylated α-, β- and γ-cyclodextrins

Kristian JaquesW. BudaMieke PottieJohan Van der EyckenMaurits VandewalleArnold VenemaPatrick Sandra

1993

Enantioselective separation by capillary GC on derivatized cyclodextrins : Part 2. Determination of the enantiomeric excess of some racemic 2,3-isopropylidene-1,2,3-cyclohexanetriol derivatives on permethyl a-, ß- and -y-cyclodextrins

Kristian JaquesW BudaL DumortierJohan Van der EyckenArnold VenemaPatrick Sandra

1992

Capillary GC enantioselective separations on a-, ß- and y-cyclodextrins : part 1 : separation of some racemic 2,3-isopropylidene-l,2,3-cyclohexanetriol derivatives

Kristian JaquesW BudaJohan Van der EyckenMaurits VandewallePatrick SandraArnold Venema

Capillary GC enantioselective separations on a-, ß- and y-cyclodextrins : part 2 : separation of some racemic 2,2-dimethyl-4-N-butoxycarbonyl-l,3-dioxane derivatives

Kristian JaquesW BudaJohan Van der EyckenMaurits VandewallePatrick SandraArnold Venema

SYNTHESIS OF (C-11)-SUBSTITUTED ANALOGS OF 1-ALPHA,25-DIHYDROXYVITAMIN-D3.

Christiaan D'HalleweynDirk Van HaverJohan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of (C-11)-substituted analogues of 1α,25-dihydroxyvitamin D3

Christiaan D'HalleweynDirk Van HaverJohan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The total synthesis of (+)-palitantin

Xavier DeruyttereLoïc DumortierJohan Van der EyckenMaurits Vandewalle

A1 Journal Article in SYNLETT

1991

Enantioselective total synthesis of (-)-epipodophyllotoxin and (-)-podophyllotoxin

R. Van SpeybroeckH. GuoJohan Van der EyckenMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Revision of the enantiotoposelective PLE-catalyzed hydrolysis of cis-5-substituted-1,3-diacyloxycyclohexanes

Loïc DumortierMiguel CardaJohan Van der EyckenG. SnatzkeMaurits Vandewalle

A1 Journal Article in TETRAHEDRON-ASYMMETRY

The synthesis of optically-active derivatives of erythritol

Mieke PottieJohan Van der EyckenMaurits VandewalleH. Röper

A1 Journal Article in TETRAHEDRON-ASYMMETRY

1990

Enantiotoposelective PLE-catalyzed hydrolysis of cis-5-substituted-1,3-diacyloxycyclohexanes : preparation of some useful chiral building blocks

M CardaJohan Van der EyckenMaurits Vandewalle

A1 Journal Article in TETRAHEDRON-ASYMMETRY

1989

Enzymatic enantioselective hydrolysis of 2,2-dimethyl-1,3-dioxolane-4-cardboxylic esters

Mieke PottieJohan Van der EyckenMaurits VandewalleJM DewanckeleH Röper

A1 Journal Article in TETRAHEDRON LETTERS

Enzymatic preparation of optically active bicyclo (2.2.1)heptene derivatives, building blocks for terpenoid natural products : an attractive alternative to enantioselective Diels-Alder syntheses

Johan Van der EyckenMaurits VandewalleG HeinemannK LaumenMP SchneiderJ KredelJ Sauer

A1 Journal Article in JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS

Synthesis of chiral non-racemic building blocks derive from 1, 2, 3- and 1, 3, 5-cyclohexanetriols by enzymatic differentiation

L. DumortierM. CardaJohan Van der EyckenMaurits Vandewalle

The synthesis of 2-azapodophyllotoxins

Jean-Paul BosmansJohan Van der EyckenMaurits VandewalleA HulkenbergR VanhesW Veerman

A1 Journal Article in TETRAHEDRON LETTERS

The synthesis of 4 desoxy-2-azapodophyllotoxins

Johan Van der EyckenJean-Paul BosmansDirk Van HaverMaurits VandewalleA HulkenbergW VeermanR Nieuwenhuizen

A1 Journal Article in TETRAHEDRON LETTERS

The synthesis of chiral isopropylidene derivatives of 1,2,3-cyclohexanetriols by enzymatic differentiation

Loïc DumortierJohan Van der EyckenMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

1987

Total synthesis of cyclopentanoid natural products

M. VandewallePablo CallantErik Van der EyckenJohan Van der EyckenL. QuaghebeurD. De Keukeleire

1986

24(R), 25-Dihydroxycholesterol : an attempt for side-chain stereocontrol via iodolactonization

Johan Van der EyckenL Van WabeekeMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

De totaalsynthese van popophyllotoxin en epipopophyllotoxin

Johan Van der EyckenM. Vandewalle

Iridoids : enantioselective synthesis of loganin via an asymmetric diels-alder reaction

Maurits VandewalleJohan Van der EyckenW OppolzerC Vullioud

A1 Journal Article in TETRAHEDRON

Iridoids : the structure elucidation of specionin based on chemical evidence and 1H NMR analysis

Erik Van der EyckenAndré De BruynJohan Van der EyckenP CallantMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Total synthesis of (±)-podophyllotoxin and (±)-epipodophyllotoxin

Johan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Total synthesis of podophyllum lignans : an exploratory study

Johan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

1985

Iridoids : the revised structure of specionin

Erik Van der EyckenJohan Van der EyckenMaurits Vandewalle

A1 Journal Article in JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS

Total synthesis of (±)-podophyllotoxin and (±)-epipodophyllotoxin

Johan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

1984

X-ray diffraction study of (±)-5α- [2′-hydroxy-1'-methoxycarbonyl-2'-(3″,4″,5″-trimethoxyphenyl) ethyl)-4α-(3″'-4″'-methylenedioxyphenyl)-2α-phenyl-1,3-dioxane

C Piccinni-LeopardiJP DeclercqG GermainM van MeersscheJohan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Chemo-enzymatic total synthesis of some conduritols, carbasugars and (+)-fortamine. Book Carbohydrate Mimics, concepts and methods, Ed. by Yves Chapleur. Carbohydrate Mimics, 1998,209-221.

L DUMORTIERP LIUJohan Van der EyckenMaurits Vandewalle