Research Explorer

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Researcher

Jeroen Vierstraete

Awards & Distinctions

25 Results

2023

Atm deficient zebrafish model reveals conservation of the tumour suppressor function and a role in fertility

Jeroen VierstraeteCharlotte FieuwsDavid CreytensJo Van DorpeAndy WillaertAnne VralKathleen Claes

Editorial material

2021

Zebrafish as an in vivo screening tool to establish PARP inhibitor efficacy

Jeroen VierstraeteCharlotte FieuwsAndy WillaertAnne VralKathleen Claes

A1 Journal Article in DNA REPAIR

2020

Association of genomic domains in BRCA1 and BRCA2 with prostate cancer risk and aggressiveness

Vivek L. PatelEvan L. BuschTara M. FriebelAngel CroninGoska LeslieLesley McGuffogJulian AdlardSimona AgataBjarni A. AgnarssonMunaza Ahmed et al.

A1 Journal Article in CANCER RESEARCH

Atm deficient zebrafish model reveals conservation of the tumour suppressor function

Jeroen VierstraeteCharlotte FieuwsDavid CreytensJo Van DorpeAndy WillaertAnne VralKathleen Claes

Characterization of the cancer spectrum in men with germline BRCA1 and BRCA2 pathogenic variants : results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Valentina SilvestriGoska LeslieDaniel R. BarnesBjarni A. AgnarssonKristiina AittomäkiElisa AlducciIrene L. AndrulisRosa B. BarkardottirAlicia BarrosoDaniel Barrowdale et al.

A1 Journal Article in JAMA ONCOLOGY

Decreased DNA double‑strand break repair and enhanced chromosomal radiosensitivity in irradiated non‑tumorigenic human breast epithelial cells with a partial BRCA1 or BRCA2 knockdown

Annelot BaertMaria PalermoMattias Van HeetveldeBram VerstraeteJulie DepuydtJeroen VierstraeteJan PhilippéAnna SablinaGianpaolo PerlettiKathleen Claes et al.

A2 Journal Article in WORLD ACADEMY OF SCIENCES JOURNAL

Isolation and engraftment of circulating tumor cells into zebrafish embryos to predict tumor response of ovarian cancer patients

Charlotte FieuwsJeroen VierstraeteKoen Van de VijverHannelore DenysKathleen Claes

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

Daniel R. BarnesMatti A. RookusLesley McGuffogGoska LeslieThea M. MooijJoe DennisNasim MavaddatJulian AdlardMunaza AhmedKristiina Aittomäki et al.

A1 Journal Article in GENETICS IN MEDICINE

Zebrafish as a model to study DNA repair and developmental defects following loss of Brca2 or Atm

Jeroen VierstraeteKathleen ClaesAnne Vral

2019

Faithfully recapitulating PARP inhibitor efficacy in zebrafish

Jeroen VierstraeteCharlotte FieuwsAndy WillaertAnne VralKathleen Claes

Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers

Frank QianMatti A RookusGoska LeslieHarvey A RischMark H GreeneCora M AalfsMuriel A AdankJulian AdlardBjarni A AgnarssonMunaza Ahmed et al.

A1 Journal Article in BRITISH JOURNAL OF CANCER

The zebrafish as an emerging model to study DNA damage in aging, cancer and other diseases

Maria Luisa CayuelaKathleen ClaesMiguel Godinho FerreiraCatarina Martins HenriquesFredericus van EedenMáté VargaJeroen VierstraeteMaria Caterina Mione

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

2018

Uncovering the role of atm in zebrafish

Jeroen VierstraeteAnne VralPaul CouckeAndy WillaertKathleen Claes

Uncovering the role of zebrafish in atm

Jeroen VierstraeteAndy WillaertPaul CouckeAnne VralKathleen Claes

Uncovering the role of zebrafish in atm

Jeroen VierstraeteAndy WillaertPaul CouckeAnne VralKathleen Claes

2017

Accurate Quantification of Homologous Recombination in Zebrafish: brca2 deficiency as a paradigm

Jeroen VierstraeteAndy WillaertPetra VermassenLeen PietersAnne VralKathleen Claes

Accurate quantification of homologous recombination : a zebrafish BRCA2-/- model

Jeroen VierstraeteAndy WillaertPetra VermassenLeen PietersPaul CouckeAnne VralKathleen Claes

Accurate quantification of homologous recombination : a zebrafish brca2-/- model

Jeroen VierstraeteAndy WillaertPetra VermassenLeen PietersPaul CouckeAnne VralKathleen Claes

Accurate quantification of homologous recombination in zebrafish : brca2 deficiency as a paradigm

Jeroen VierstraeteAndy WillaertPetra VermassenPaul CouckeAnne VralKathleen Claes

A1 Journal Article in SCIENTIFIC REPORTS

Study of homologous recombination repair in BRCA2 knockout zebrafish embryos

Jeroen VierstraeteAndy WillaertPaul CouckeAnne VralKathleen Claes

Study of homologous recombination repair in BRCA2 knockout zebrafish embryos

Jeroen VierstraeteAndy WillaertPaul CouckeAnne VralKathleen Claes

2016

Studying the functionality of the homologous repair pathway in zebrafish embryos : heading for an in vivo functional test to evaluate the pathogenicity of BRCA2 variants

Jeroen VierstraeteAndy WillaertKris VleminckxPetra VermassenLeen PietersPaul CouckeAnne VralKathleen Claes

Studying the functionality of the homologous repair pathway in zebrafish embryos : heading for an in vivo functional test to evaluate the pathogenicity of BRCA2 variants identified in breast/ovarian cancer patients

Jeroen VierstraeteAndy WillaertPetra VermassenLeen PietersPaul CouckeAnne VralKathleen Claes

Studying the functionality of the homologous repair pathway in zebrafish embryos : heading for an in vivo functional test to evaluate the pathogenicity of BRCA2 variants identified in breast/ovarian cancer patients

Jeroen VierstraeteAndy WillaertPetra VermassenLeen PietersPaul CouckeAnne VralKathleen Claes

Studying the functionality of the homologous repair pathway in zebrafish embryos : heading for an in vivo functional test to evaluate the pathogenicity of BRCA2 variants identified in breast/ovarian cancer patients

Jeroen VierstraeteAndy WillaertPetra VermassenLeen PietersPaul CouckeAnne VralKathleen Claes