Research Explorer

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Researcher

Jeroen Spanoghe

Publications & Research Data

Awards & Distinctions

15 Results

2026

Feedback control of excitability and high K+ induced epileptiform bursts in male rat hippocampal slices with a photocaged adenosine A1 receptor agonist

Erine CraeyMarijke VergaelenSerge Van CalenberghJeroen SpanogheEvelien CarretteKristl VonckPaul BoonWytse WadmanRobrecht Raedt

A1 Journal Article in BRITISH JOURNAL OF PHARMACOLOGY

2025

Effects of intracerebroventricular administration of dimethyl sulfoxide on hippocampal electrophysiology in mice

Jeroen SpanogheArne Van AckerEvelien CarretteKristl VonckPaul BoonRobrecht Raedt

A2 Journal Article in IBRO NEUROSCIENCE REPORTS

Embedded system for responsive optogenetic control of spontaneous seizures in a preclinical temporal lobe epilepsy model

Sofie LasureLien De SchaepmeesterSielke CaesteckerJeroen SpanogheMarijke VergaelenRik VerplanckeJohannes VierockRobrecht RaedtPieter Bauwens

Photopharmacological activation of adenosine A1 receptor signaling suppresses seizures in a mouse model for temporal lobe epilepsy

Jeroen SpanogheEvelien WynendaeleMarijke VergaelenMaren De ColvenaerTina MarimanKristl VonckEvelien CarretteWytse WadmanErine CraeyLars Emil Larsen et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Photopharmacological adenosine A1 receptor modulation for the suppression of epileptic seizures : a proof of concept

Jeroen SpanoghePaul BoonRobrecht Raedt

2024

Embedded system for responsive optogenetic control of spontaneous seizures in temporal lobe epilepsy

Sofie LasureJeroen SpanogheMarijke VergaelenRik VerplanckePieter BauwensRobrecht Raedt

Increased dentate gyrus excitability in the intrahippocampal kainic acid mouse model for temporal lobe epilepsy

Marijke VergaelenSimona ManzellaKristl VonckErine CraeyJeroen SpanogheMathieu SprengersEvelien CarretteWytse Jan WadmanJean DelbekePaul Boon et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Photopharmacology in the spotlight : spatially selective adenosinergic modulation of hippocampal excitability in the pursuit of therapeutic innovation in temporal lobe epilepsy

Marijke VergaelenJeroen SpanogheJeroen MissinneSerge Van CalenberghPaul BoonKristl VonckRobrecht Raedt

Towards therapeutic innovation in temporal lobe epilepsy : focal adenosinergic modulation of hippocampal excitability

Marijke VergaelenJeroen SpanogheJeroen MissinneSerge Van CalenberghKristl VonckPaul BoonRobrecht Raedt

2023

Focal adenosine A1 receptor activation through photopharmacology as a potential treatment for drug-resistant epilepsy

Jeroen SpanogheLars Emil LarsenErine CraeySimona ManzellaKristl VonckSerge Van CalenberghPaul BoonR. Raedt

Investigating the effect of photopharmacological interventions on cortical seizures using organic perforated multielectrode arrays

Sofia DrakopoulouLinta SohailJeroen SpanogheDina K CRobrecht RaedtGeorge D. Spyropoulos

Soft, flexible, and biocompatible technologies for optical sensing and stimulation in biomedical applications

Jeroen MissinneXavier De BeckerFederico PazzagliaWouter Van LysebettensAnastasiia BabychJeroen SpanogheMarijke VergaelenRobrecht RaedtPieter BauwensSandra Van Vlierberghe et al.

2022

Ex vivo feedback control of neurotransmission using a photocaged adenosine A1 receptor agonist

Erine CraeyFabian HulpiaJeroen SpanogheSimona ManzellaLars Emil LarsenMathieu SprengersDimitri De BundelIlse SmoldersEvelien CarretteJean Delbeke et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2021

Feedback control of CA1 excitability in hippocampal slices with a photoactive adenosine A1 receptor agonist

Erine CraeyJeroen SpanogheSerge Van CalenberghLars Emil LarsenEvelien CarretteJean DelbekeKristl VonckPaul BoonWytse WadmanRobrecht Raedt

The signaling pathways involved in the anticonvulsive effects of the adenosine A1 receptor

Jeroen SpanogheLars Emil LarsenErine CraeySimona ManzellaAnnelies Van DyckePaul BoonRobrecht Raedt

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES