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Researcher
Jelle De Medts
Profile
Projects
Publications
Activities
Awards & Distinctions
9
Results
2020
Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development
Anne-Catherine Dolens
Kaat Durinck
Marieke Lavaert
Joni Van der Meulen
Imke Velghe
Jelle De Medts
Karin Weening
Juliette Roels
Katrien De Mulder
Pieter-Jan Volders
et al.
A1
Journal Article
in
EMBO REPORTS
2020
2019
ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms
Steven Goossens
Jueqiong Wang
Cedric Tremblay
Jelle De Medts
Sara T'Sas
Thao Nguyen
Jesslyn Saw
Katharina Haigh
David J Curtis
Pieter Van Vlierberghe
et al.
A1
Journal Article
in
HAEMATOLOGICA
2019
2016
GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate
Inge Van de Walle
Anne-Catherine Dolens
Kaat Durinck
Katrien De Mulder
Wouter Van Loocke
Sagar Damle
Els Waegemans
Jelle De Medts
Imke Velghe
Magda De Smedt
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2016
2015
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling
Steven Goossens
Enrico Radaelli
Odile Blanchet
Kaat Durinck
Joni Van der Meulen
Sofie Peirs
Tom Taghon
Cedric S Tremblay
Magdaline Costa
Morvarid Farhang Ghahremani
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2015
2014
Notch3 activation is sufficient but not required for inducing human T-lineage specification
Els Waegemans
Inge Van de Walle
Jelle De Medts
Magda De Smedt
Tessa Kerre
Bart Vandekerckhove
Georges Leclercq
Tao Wang
Jean Plum
Tom Taghon
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2014
2013
Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength
Inge Van de Walle
Els Waegemans
Jelle De Medts
Greet De Smet
Magda De Smedt
Sylvia Snauwaert
Bart Vandekerckhove
Tessa Kerre
Georges Leclercq
Jean Plum
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2013
2012
Notch ligands control the human alpha beta/gamma delta lineage choice through receptor-specific induction of differential Notch signal strength
Tom Taghon
Inge Van de Walle
Els Waegemans
Jelle De Medts
Greet De Smet
Magda De Smedt
Bart Vandekerckhove
Tessa Kerre
Georges Leclercq
Tao Wang
et al.
C3
Conference
2012
2011
Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern
Seppe Vander Beken
Juma'a R Al Dulayymi
Thomas Naessens
Gani Koza
Max Maza-Iglesias
Richard Rowles
Cornelia Theunissen
Jelle De Medts
Ellen Lanckacker
Mark S Baird
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF IMMUNOLOGY
2011
cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)
Mathieu Bertrand
Saskia Lippens
An Staes
Barbara Gilbert
Ria Roelandt
Jelle De Medts
Kris Gevaert
Wim Declercq
Peter Vandenabeele
A1
Journal Article
in
PLOS ONE
2011