Research Explorer

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Researcher

Jef Willems

Publications & Research Data

Awards & Distinctions

30 Results

2026

Developing tailored dosing recommendations for ciprofloxacin in critically ill children using a population approach based on total and unbound concentrations

Pieter-Jan De SutterEvelyn DhontDaphne VensPeter De PaepeJef WillemsPetra SchelstraeteJan Van BocxlaerAn VermeulenPieter De Cock

A1 Journal Article in CLINICAL MICROBIOLOGY AND INFECTION

2025

Developing evidence-based dosing recommendations for intravenous ciprofloxacin in critically ill children: a population pharmacokinetic study using total and unbound concentrations

Pieter-Jan De SutterEvelyn DhontDaphné VensPeter De PaepeJef WillemsPetra SchelstraeteJan Van BocxlaerAn VermeulenPieter De Cock

2024

Predictors of augmented renal clearance based on iohexol plasma clearance in critically ill children

Evelyn DhontTatjana Van Der HeggenEvelien SnauwaertJef WillemsSiska CroubelsJoris DelangheJan De WaeleRoos ColmanJohan Vande WallePeter De Paepe et al.

A1 Journal Article in PEDIATRIC NEPHROLOGY

The hyperPed-COVID international registry : impact of age of onset, disease presentation and geographical distribution on the final outcome of MIS-C

Roberta CaorsiAlessandro ConsolaroCamilla SpezianiBetul SozeriKadir UluEnrique Faugier-FuentesHector Menchaca-AguayoSeza OzenSeher SenerShahana Akhter Rahman et al.

A1 Journal Article in JOURNAL OF AUTOIMMUNITY

The use of information technology to improve interdisciplinary communication during infectious diseases ward rounds on the paediatric intensive care unit

Jef WillemsAdeline HeyndrickxPetra SchelstraeteBram GadeynePieter De CockStien VandendriesschePieter Depuydt

A1 Journal Article in SCIENTIFIC REPORTS

2023

Anterior and posterior tracheopexy for severe tracheomalacia

Thomas MartensHeidi SchaballieJulie WillekensPetra SchelstraeteJef WillemsNagarajan MuthialuLiesbeth Desender

A2 Journal Article in JTCVS TECHNIQUES

Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes : an international multicentre retrospective study

Roelie M. Wosten-van AsperenHannah M. la Roi-TeeuwRombout B. E. van AmstelLieuwe D. J. BosWim J. E. TissingIolanda JordanChristian Dohna-SchwakeGabriella BottariJohn PappachanRoman Crazzolara et al.

A1 Journal Article in ECLINICALMEDICINE

Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children : a propensity-weighted cohort study

Samuel Channon-WellsOrtensia VitoAndrew J McArdleEleanor G SeabyPriyen ShahEkaterina PazukhinaClare WilsonClaire BroderickGiselle D'SouzaIlana Keren et al.

A1 Journal Article in LANCET RHEUMATOLOGY

2022

Organizational characteristics of European pediatric onco-critical care : an international cross-sectional survey

Jeppe S. A. NielsenRachel AgbekoJessica BateIolanda JordanChristian Dohna-SchwakeJenny PotratzAndrea MoscatelliGabriella BottariJohn PappachanVolker Witt et al.

A1 Journal Article in FRONTIERS IN PEDIATRICS

Risk factors of augmented renal clearance in critically ill children using iohexol clearance for renal function assessment

Evelyn DhontTatjana Van Der HeggenEvelien SnauwaertJef WillemsSiska CroubelsJoris DelangheJohan Vande WallePeter De PaepePieter De Cock

Role of extracorporeal membrane oxygenation in pediatric cancer patients : a systematic review and meta-analysis of observational studies

Valerie SlooffRianne HoogendoornJeppe Sylvest Angaard NielsenJohn PappachanAngela AmigoniFabio CaramelliOmer AzizEnno WildschutSascha VerbruggenRoman Crazzolara et al.

A1 Journal Article in ANNALS OF INTENSIVE CARE

Sensitivity and specificity of 14 SARS-CoV-2 serological assays and their diagnostic potential in RT-PCR negative COVID-19 infections

Eveline Van HonackerLiselotte CoorevitsJerina BoelensBruno VerhasseltEva Van BraeckelFre BautersLiesbet De BusPetra SchelstraeteJef WillemsStien Vandendriessche et al.

A1 Journal Article in ACTA CLINICA BELGICA

Suboptimal beta-lactam therapy in critically ill children : risk factors and outcome

Tatjana Van Der HeggenEvelyn DhontJef WillemsINGRID HERCKJoris DelangheVeronique StoveAlain VerstraeteSophie VanhaesebrouckPeter De PaepePieter De Cock

A1 Journal Article in PEDIATRIC CRITICAL CARE MEDICINE

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Levi HosteLisa RoelsLeslie NaesensVictor BosteelsStijn VanheeSam DupontCedric BosteelsRobin BrowaeysNiels VandammeKevin Verstaen et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Whole blood tcr vβ21.3 staining as a diagnostic test for multisystem inflammatory syndrome in children : a proof-of-concept study

Levi HosteJef WillemsEvelyn DhontPetra SchelstraeteJo DehoorneKristof VandekerckhoveAlexandre BelotBrigitte Bader-MeunierChristophe MalcusSimon Tavernier et al.

2021

Optimizing the use of antibiotic agents in the pediatric intensive care unit : a narrative review

Jef WillemsEline HermansPetra SchelstraetePieter DepuydtPieter De Cock

A1 Journal Article in PEDIATRIC DRUGS

Purpura fulminans : how varicella zoster can result in acquired protein S deficiency

Frederick VerbekeBram De WildeJef WillemsKatrien Devreese

Editorial material

2019

Accuracy of renal function estimating equations compared to iohexol clearance in critically ill children

Evelyn DhontCharlotte WindelsTatjana Van Der HeggenANNIK DE JAEGERJef WillemsSiska CroubelsSiegrid De BaereJohan Vande WallePeter De PaepePieter De Cock

Comparison of renal function estimation methods in critically ill children : a pilot study

Evelyn DhontTatjana Van Der HeggenANNIK DE JAEGERJef WillemsSiska CroubelsSiegrid De BaereJohan Vande WallePeter De PaepePieter De Cock

PICU mortality of children with cancer admitted to pediatric intensive care unit : a systematic review and meta-analysis

Roelie M Wösten-van AsperenJosephus PJ van GestelMartine van GrotelEva TschiedelChristian Dohna-SchwakeFrédéric V VallaJef WillemsJeppe S Angaard NielsenMartin F KrauseJenny Potratz et al.

A1 Journal Article in CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Research priorities in pediatric onco-critical care : an international Delphi consensus study

Marijn SoetemanJenny PotratzJeppe S. Angaard NielsenJef WillemsFrédéric V VallaJoe BrierleyRoelie M Wösten-van Asperen

A1 Journal Article in INTENSIVE CARE MEDICINE

2018

Assessment of renal function in the critically ill child : focus on augmented renal clearance

Evelyn DhontJef WillemsAnn VerrijcktANNIK DE JAEGERJohan Vande WallePeter De PaepePieter De Cock

A2 Journal Article in BELGIAN JOURNAL OF PAEDIATRICS

Severe anaphylactic reaction following anti-thymocyte globulin administration in a pediatric stem cell transplantation patient

Tieneke BautersMaria Bordon Cueto De BraemJef WillemsBram De WildeGenevieve Laureys

A1 Journal Article in JOURNAL OF ONCOLOGY PHARMACY PRACTICE

Subtherapeutic antimicrobial plasma concentrations with standard amoxicillin-clavulanate dosing regimens in paediatric cardiac surgery patients

Evelyn DhontJef WillemsWim VandenbergheMieke CarlierAlain VerstraeteJohan Vande WallePeter De PaepePieter De Cock

2017

Dose optimization of piperacillin/tazobactam in critically ill children

Pieter De CockSven C van DijkmanANNIK DE JAEGERJef WillemsMieke CarlierAlain VerstraeteJoris DelangheHugo RobaysJohan Vande WalleOscar E Della Pasqua et al.

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

2016

Piperacollin-tazobactam pharmacokinetis- pharmacodynamics implies a need for higher dosing in critically ill children

Pieter De CockSven Van DijckmanAnnick De JaegerJef WillemsMieke CarlierAlain VerstraeteJoris DelangheHugo RobaysJohan Vande WalleOscar Della Pasqua et al.

2013

Expanding the spectrum of MERS type 2 lesions, a particular form of encephalitis

ANNELEEN NOTEBAERTJef WillemsLine CouckeRudy Van CosterHelene Verhelst

A1 Journal Article in PEDIATRIC NEUROLOGY

2010

Anesthesia and perioperative management for a patient with Ullrich syndrome undergoing surgery for scoliosis

Wim VandenbergheTOM JACOBSFrank PlasschaertJef WillemsNADIA DEN BLAUWENHUGO VEREECKEPatrick Wouters

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

2009

A potentially life-treatening complication after a blood transfusion : the importance of clinical awareness

Pauline De BruyneInge Van HauteANNIK DE JAEGERJef Willems

2004

Ergotamine as a possible cause of Mobius sequence: Additional clinical observation

Koenraad SmetsAleksandra ZecicJef Willems

A1 Journal Article in JOURNAL OF CHILD NEUROLOGY