Research Explorer

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Researcher

Jasin Taelman

Awards & Distinctions

19 Results

2021

Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells

Swati MishraJasin TaelmanMina PopovicLaurentijn TillemanEvi DuthooMargot Van der JeughtDieter DeforceFilip Van NieuwerburghBjörn MentenPetra De Sutter et al.

A1 Journal Article in STEM CELLS

Sex-specific isolation and propagation of human premeiotic fetal germ cells and germ cell-like cells

Swati MishraJasin TaelmanYolanda W. ChangAnnekatrien BoelPetra De SutterBjörn HeindryckxSusana Marina Chuva de Sousa Lopes

A1 Journal Article in CELLS

2020

Navigating pluripotency : resetting the primed state and exploring histone modification dynamics in human embryonic stem cells

Jasin TaelmanPetra De SutterDieter Deforce

2019

Human blastocyst outgrowths recapitulate primordial germ cell specification events

Mina PopovicMonika BialeckaMaria Gomes FernandesJasin TaelmanMargot Van der JeughtPetra De SutterBjörn HeindryckxSusana Marina Chuva de Sousa Lopes

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Increased primordial germ cell (PGC) specification from human embryonic stem cells (hESC) derived in Activin A

Swati MishraMargot Van der JeughtMina PopovicJasin TaelmanEvi DuthooKatarzyna Joanna Szymańska-VandendriesschePetra De SutterLaurentijn TillemanFilip Van NieuwerburghAnnekatrien Boel et al.

Untargeted histone profiling during naive conversion uncovers conserved modification markers between mouse and human

Laura De ClerckJasin TaelmanMina PopovicSander WillemsMargot Van der JeughtBjörn HeindryckxPetra De SutterHendrik MarksDieter DeforceMaarten Dhaenens

A1 Journal Article in SCIENTIFIC REPORTS

WNT inhibition and increased fibroblast growth factor signaling promotes derivation of less heterogeneous primed human embryonic stem cells, compatible with differentiation

Jasin TaelmanMina PopovicMonika BialeckaLaurentijn TillemanSharat WarrierMargot Van der JeughtBjörn MentenDieter DeforcePetra De SutterFilip Van Nieuwerburgh et al.

A1 Journal Article in STEM CELLS AND DEVELOPMENT

2018

Chromosomal mosaicism in human blastocysts : the ultimate challenge of preimplantation genetic testing?

Mina PopovicAnnelies DheedeneCHRISTODOULOS CHRISTODOULOUJasin TaelmanLien DhaenensFilip Van NieuwerburghDieter DeforceEtienne Van den AbbeelPetra De SutterBjörn Menten et al.

A1 Journal Article in HUMAN REPRODUCTION

Impact of pluripotency state and Activin A supplementation on derivation of primordial germ cell-like cells from human

Swati MishraMargot Van der JeughtJasin TaelmanMina PopovicKatarzyna Joanna Szymańska-VandendriesscheDieter DeforcePetra De SutterSusana Marina Chuva de Sousa LopesBjörn Heindryckx

Stem cell-derived spermatozoa

Jasin TaelmanSwati MishraMargot Van der JeughtBjörn Heindryckx

Bookchapter in Reproductomics : the -omics revolution and its impact on human reproductive medicine

Transcriptional landscape changes during human embryonic stem cell derivation

Sharat WarrierJasin TaelmanLaurentijn TillemanMargot Van der JeughtGalbha DuggalSylvie LiermanMina PopovicAnn Van SoomLuc PeelmanFilip Van Nieuwerburgh et al.

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Unravelling the molecular pathways responsible for sex determination in humans

Jasin TaelmanMina PopovicLaurentijn TillemanMargot Van der JeughtDieter DeforcePetra De SutterFilip Van NieuwerburghBjörn HeindryckxS Chuva De Sousa Lopes

2017

Direct comparison of distinct naive pluripotent states in human embryonic stem cells

Sharat WarrierMargot Van der JeughtGalbha DuggalLaurentijn TillemanElla SutherlandJasin TaelmanMina PopovicSylvie LiermanSusana Marina Chuva de Sousa LopesAnn Van Soom et al.

A1 Journal Article in NATURE COMMUNICATIONS

Origins of human embryonic stem cell fate : role of the post inner cell mass intermediate

Sharat WarrierMina PopovicJasin TaelmanLaurentijn TillemanSylvie LiermanMinerva Ferrer BuitragoS. Chuva De Sousa LopesAnn Van SoomLuc PeelmanFilip Van Nieuwerburgh et al.

Wnt inhibition during hESC culture provides an improved pluripotent state starting point for directed differentiation

Jasin TaelmanLaurentijn TillemanFilip Van NieuwerburghSharat WarrierMina PopovicMargot Van der JeughtDieter DeforcePetra De SutterBjörn HeindryckxSusana Marina Chuva de Sousa Lopes

2016

Uncovering the novel role of mTORC2 subunit of the PI3K/AKT/mTORC pathway in establishing naive pluripotency in human embryonic stem cells

Sharat WarrierMargot Van der JeughtGalbha DuggalJasin TaelmanSylvie LiermanSusana Marina Chuva de Sousa LopesAnn Van SoomLuc PeelmanFilip Van NieuwerburghDieter De Coninck et al.

2015

Application of small molecules favoring naive pluripotency during human embryonic stem cell derivation

Margot Van der JeughtJasin TaelmanGalbha DuggalSabitri GhimireSylvie LiermanSusana Marina Chuva de Sousa LopesDieter DeforceTom DerooPetra De SutterBjörn Heindryckx

A1 Journal Article in CELLULAR REPROGRAMMING

Comparative analysis of different culture conditions inducing naive pluripotency in human embryonic stem cells

Sharat WarrierGalbha DuggalJasin TaelmanSylvie LiermanS Chuva de Sousa LopesAnn Van SoomLuc PeelmanFilip Van NieuwerburghDieter De ConinckBjörn Menten et al.

Exogenous supplementation of Activin A enhances germ cell differentiation of human embryonic stem cells

Galbha DuggalBjörn HeindryckxSharat WarrierJasin TaelmanMargot Van der JeughtDieter DeforceSusana Marina Chuva de Sousa LopesPetra De Sutter

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION