Research Explorer

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Researcher

Jana Desloovere

Awards & Distinctions

24 Results

2023

Chemogenetic seizure suppression in a mouse model for temporal lobe epilepsy : 'pumping up the jam'?

Tjip HuysmansRobrecht RaedtJana Desloovere

2022

Chemogenetic seizure control with clozapine and the novel ligand JHU37160 outperforms the effects of Levetiracetam in the intrahippocampal kainic acid mouse model

Jana DeslooverePaul BoonLars Emil LarsenMarie-Gabrielle GoossensJean DelbekeEvelien CarretteWytse WadmanKristl VonckRobrecht Raedt

A1 Journal Article in NEUROTHERAPEUTICS

Chemogenetic seizure control with clozapine and the novel ligand JHU37160 outperforms the effects of levetiracetam in the intrahippocampal kainic acid mouse model

Jana DeslooverePaul BoonLars Emil LarsenMarie-Gabrielle GoossensJean DelbekeEvelien CarretteWytse WadmanKristl VonckRobrecht Raedt

A1 Journal Article in NEUROTHERAPEUTICS

Preclinical evaluation of chemogenetics as a new treatment for drug-resistant epilepsy

Jana DeslooverePaul BoonRobrecht Raedt

2021

Level of hM4D(Gi) DREADD expression determines inhibitory and neurotoxic effects in the hippocampus

Marie-Gabrielle GoossensLars Emil LarsenMarijke VergaelenWytse WadmanChris Van den HauteWayra BrackxSilke ProesmansJana DesloovereEmma ChristiaenErine Craey et al.

A1 Journal Article in ENEURO

Long‐term chemogenetic suppression of seizures in a multifocal rat model of temporal lobe epilepsy

Marie-Gabrielle GoossensPaul BoonWytse WadmanChris Van den HauteVeerle BaekelandtAlain VerstraeteKristl VonckLars Emil LarsenMathieu SprengersEvelien Carrette et al.

A1 Journal Article in EPILEPSIA

Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission

Anna KreisJana DesloovereNuria SuelvesNathalie PierrotXavier YernaFarah IssaOlivier SchakmanRoberta GualdaniMarie de ClippeleNicolas Tajeddine et al.

A1 Journal Article in SCIENTIFIC REPORTS

2020

Ambulatory electrocardiographic monitoring and ectopic beat detection in conscious mice

Felke SteijnsMáté István TóthAnthony DemolderLars Emil LarsenJana DesloovereMarjolijn RenardRobrecht RaedtPatrick SegersJulie De BackerPatrick Sips

A1 Journal Article in SENSORS

Spontaneous right ventricular pseudoaneurysms and increased arrhythmogenicity in a mouse model of Marfan syndrome

Felke SteijnsMarjolijn RenardMarine VanhomwegenPetra VermassenJana DesloovereRobrecht RaedtLars Emil LarsenMáté István TóthJulie De BackerPatrick Sips

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2019

Chemogenetic suppression of spontaneous seizures in a rat model for temporal lobe epilepsy

Marie-Gabrielle GoossensEmma ChristiaenPaul BoonKristl VonckEvelien CarretteJana DesloovereChris Van Den HauteVeerle BaekelandtWytse WadmanChristian Vanhove et al.

Chemogenetic suppression of spontaneous seizures in a rat model for temporal lobe epilepsy

Marie-Gabrielle GoossensEmma ChristiaenPaul BoonKristl VonckEvelien CarretteJana DesloovereChris Van Den HauteVeerle BaekelandtWytse WadmanChristian Vanhove et al.

Chemogenetic suppression of spontaneous seizures in a rat model for temporal lobe epilepsy

Marie-Gabrielle GoossensEmma ChristiaenPaul BoonKristl VonckEvelien CarretteJana DesloovereChris Van Den HauteVeerle BaekelandtWytse WadmanChristian Vanhove et al.

Chemogenetic therapy strongly suppresses hippocampal excitability and spontaneous seizures in a rat model for temporal lobe epilepsy

Marie-Gabrielle GoossensPaul BoonEmma ChristiaenKristl VonckEvelien CarretteJana DesloovereChris Van den HauteVeerle BaekelandtWytse WadmanChristian Vanhove et al.

Effect of chemogenetic modulation of hippocampal neurons on depression and spatial memory impairment in a rat model for temporal lobe epilepsy

Erine CraeyMarie-Gabrielle GoossensJana DesloovereCaroline MerckxChris Van Den HauteVeerle BaekelandtDimitri De BundelIlse SmoldersKristl VonckPaul Boon et al.

Effect of chemogenetic modulation of hippocampal neurons on depression and spatial memory impairment in a rat model for temporal lobe epilepsy

Erine CraeyMarie-Gabrielle GoossensJana DesloovereCaroline MerckxChris Van Den HauteVeerle BaekelandtDimitri De BundelIlse SmoldersKristl VonckPaul Boon et al.

Long-term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy.

Jana DeslooverePaul BoonLars Emil LarsenCaroline MerckxMarie-Gabrielle GoossensC Van den HauteV BaekelandtD De BundelEvelien CarretteJean Delbeke et al.

A1 Journal Article in EPILEPSIA

2018

Chemogenetic silencing of excitatory hippocampal neurons prevents spontaneous seizures in a mouse model for temporal lobe epilepsy

Jana DesloovereMarie-Gabrielle GoossensChris Van den HauteVeerle BaeckelandtJean DelbekeEvelien CarretteKristl VonckAlfred MeursWytse WadmanPaul Boon et al.

Chemogenetic silencing of excitatory hippocampal neurons prevents spontaneous seizures in a mouse model for temporal lobe epilepsy

Jana DesloovereMarie-Gabrielle GoossensChris Van den HauteVeerle BaeckelandtJean DelbekeEvelien CarretteKristl VonckAlfred MeursWytse WadmanPaul Boon et al.

Chemogenetic silencing of excitatory hippocampal neurons prevents spontaneous seizures in a mouse model for temporal lobe epilepsy

Jana DesloovereMarie-Gabrielle GoossensChris Van den HauteVeerle BaeckelandtJean DelbekeEvelien CarretteKristl VonckAlfred MeursWytse WadmanPaul Boon et al.

Chemogenetic silencing of excitatory hippocampal neurons prevents spontaneous seizures in a mouse model for temporal lobe epilepsy

Jana DesloovereMarie-Gabrielle GoossensChris Van den HauteVeerle BaeckelandtJean DelbekeEvelien CarretteKristl VonckAlfred MeursWytse WadmanPaul Boon et al.

Chemogenetic silencing of excitatory hippocampal neurons prevents spontaneous seizures in a mouse model for temporal lobe epilepsy

Jana DesloovereMarie-Gabrielle GoossensChris Van den HauteVeerle BaekelandtJean DelbekeEvelien CarretteKristl VonckAlfred MeursWytse WadmanPaul Boon et al.

The effect of chemogenetic inhibition of excitatory neurons on hippocampal excitability and seizure frequency in a rat model

Marie-Gabrielle GoossensJana DesloovereEmma ChristiaenWouter Van LysebettensErine CraeyAnirudh AcharyaPaul BoonKristl VonckChris Van Den HauteVeerle Baekelandt et al.

The effect of chemogenetic inhibition of excitatory neurons on hippocampal excitability and seizure frequency in a rat model

Marie-Gabrielle GoossensJana DesloovereEmma ChristiaenWouter Van LysebettensErine CraeyAnirudh AcharyaPaul BoonKristl VonckChris Van Den HauteVeerle Baekelandt et al.

The effect of chemogenetic inhibition of excitatory neurons on hippocampal excitability and seizure frequency in a rat model

Marie-Gabrielle GoossensJana DesloovereEmma ChristiaenWouter Van LysebettensErine CraeyAnirudh AcharyaPaul BoonKristl VonckChris Van Den HauteVeerle Baekelandt et al.