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Researcher
Jana De Vrieze
Profile
Projects
Publications
Activities
Awards & Distinctions
11
Results
2025
Enhancing anti-tumor immunity through intratumoral combination therapy with amphiphilic conjugates of oxaliplatin and imidazoquinoline TLR7/8 agonist
Hanne Verschuere
Sabah Kasmi
Lutz Nuhn
Senan Mickael D'Almeida
Qiwen Zhu
Zifu Zhong
Sandy Adjemian Catani
Benoit Louage
Jana De Vrieze
Haijun Yu
et al.
U
Journal Article
in
RSC ADVANCES
2025
2022
Characterization of SARS-CoV-2 spike mutations important for infection of mice and escape from human immune sera
Raveen Rathnasinghe
Sonia Jangra
Chengjin Ye
Anastasija Cupic
Gagandeep Singh
Carles Martínez-Romero
Lubbertus C. F. Mulder
Thomas Kehrer
Soner Yildiz
Angela Choi
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2022
2021
Lipid nature and alkyl length influence lymph node accumulation of lipid-polyethylene glycol amphiphiles
Jana De Vrieze
Antonio Pires da Silva Baptista
Lutz Nuhn
Simon Van Herck
Kim Deswarte
Haijun Yu
Bart Lambrecht
Bruno De Geest
A1
Journal Article
in
ADVANCED THERAPEUTICS
2021
Lipid-polymer conjugates for innate immune activation
Jana De Vrieze
Bruno De Geest
Dissertation
2021
Squaric ester-based, pH-degradable nanogels : modular nanocarriers for safe, systemic administration of toll-like receptor 7/8 agonistic immune modulators
Anne Huppertsberg
Leonard Kaps
Zifu Zhong
Sascha Schmitt
Judith Stickdorn
Kim Deswarte
Francis Combes
Christian Czysch
Jana De Vrieze
Sabah Kasmi
et al.
A1
Journal Article
in
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2021
Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine**
Sonia Jangra
Jana De Vrieze
Angela Choi
Raveen Rathnasinghe
Gabriel Laghlali
Annemiek Uvyn
Simon Van Herck
Lutz Nuhn
Kim Deswarte
Zifu Zhong
et al.
A1
Journal Article
in
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2021
2020
Control over imidazoquinoline immune stimulation by pH-degradable poly(norbornene) nanogels
Johannes Kockelmann
Judith Stickdorn
Sabah Kasmi
Jana De Vrieze
Michaela Pieszka
David Yuen W. Ng
Sunil A. David
Bruno De Geest
Lutz Nuhn
A1
Journal Article
in
BIOMACROMOLECULES
2020
Design of pH-degradable polymer-lipid amphiphiles using a ketal-functionalized RAFT chain transfer agent
Jana De Vrieze
Simon Van Herck
Lutz Nuhn
Bruno De Geest
A1
Journal Article
in
MACROMOLECULAR RAPID COMMUNICATIONS
2020
Sterilizing immunity against SARS-CoV-2 infection in mice by a single-shot and modified imidazoquinoline TLR7/8 agonist-adjuvanted recombinant spike protein vaccine
Sonia Jangra
Jana De Vrieze
Angela Choi
Raveen Rathnasinghe
Gabriel Laghlali
Annemiek Uvyn
Simon Van Herck
Lutz Nuhn
Kim Deswarte
Zifu Zhong
et al.
Preprint
2020
2019
Efficient innate immune killing of cancer cells triggered by cell-surface anchoring of multivalent antibody-recruiting polymers
Annemiek Uvyn
Ruben De Coen
Mandy Gruijs
Cees W. Tuk
Jana De Vrieze
Marjolein van Egmond
Bruno De Geest
A1
Journal Article
in
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2019
Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists
Jana De Vrieze
Benoit Louage
Kim Deswarte
Zifu Zhong
Ruben De Coen
Simon Van Herck
Lutz Nuhn
Camilla Kaas Frich
Alexander N Zelikin
Stefan Lienenklaus
et al.
A1
Journal Article
in
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2019